-
1دورية أكاديميةSmall molecule ISRIB suppresses the integrated stress response within a defined window of activation
المؤلفون: Rabouw, Huib H, Langereis, Martijn A, Anand, Aditya A, Visser, Linda J, de Groot, Raoul J, Walter, Peter, van Kuppeveld, Frank JM
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(6)
مصطلحات موضوعية: 2.1 Biological and endogenous factors, Aetiology, Acetamides, Animals, Arsenites, Cell Line, Cyclohexylamines, Eukaryotic Initiation Factor-2, Humans, Phosphorylation, Picornaviridae, Picornaviridae Infections, Poly I-C, Stress, Physiological, integrated stress response, ISRIB, P-eIF2, eIF2B
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/3ft0d5c5Test
-
2دورية أكاديمية
المؤلفون: Aloise, Chiara, Schipper, Jelle G, van Vliet, Arno, Oymans, Judith, Donselaar, Tim, Hurdiss, Daniel L, de Groot, Raoul J, van Kuppeveld, Frank J M
المساهمون: Virologie
مصطلحات موضوعية: COVID-19, DNA Helicases, Encephalomyocarditis virus, Humans, Poly-ADP-Ribose Binding Proteins, RNA Helicases, RNA Recognition Motif Proteins/genetics, RNA-Binding Motifs, SARS-CoV-2/genetics
وصف الملف: application/pdf
-
3دورية أكاديمية
المؤلفون: Wang, Chunyan, Hesketh, Emma L, Shamorkina, Tatiana M, Li, Wentao, Franken, Peter J, Drabek, Dubravka, van Haperen, Rien, Townend, Sarah, van Kuppeveld, Frank J M, Grosveld, Frank, Ranson, Neil A, Snijder, Joost, de Groot, Raoul J, Hurdiss, Daniel L, Bosch, Berend-Jan
المساهمون: Virologie, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research, Dep Biomolecular Health Sciences
مصطلحات موضوعية: Antibodies, Monoclonal, Neutralizing, Viral, COVID-19, Coronavirus OC43, Human/metabolism, Epitopes, Humans, SARS-CoV-2, Spike Glycoprotein, Coronavirus
وصف الملف: application/pdf
-
4دورية أكاديمية
المؤلفون: Langereis, Martijn A, Bakkers, Mark JG, Deng, Lingquan, Padler-Karavani, Vered, Vervoort, Stephin J, Hulswit, Ruben JG, van Vliet, Arno LW, Gerwig, Gerrit J, de Poot, Stefanie AH, Boot, Willemijn, van Ederen, Anne Marie, Heesters, Balthasar A, van der Loos, Chris M, van Kuppeveld, Frank JM, Yu, Hai, Huizinga, Eric G, Chen, Xi, Varki, Ajit, Kamerling, Johannis P, de Groot, Raoul J
المصدر: Cell reports. 11(12)
مصطلحات موضوعية: Animals, Mammals, Humans, Nidovirales, Sialic Acids, N-Acetylneuraminic Acid, Acetylesterase, Lipids, Proteins, Viral Fusion Proteins, Hemagglutinins, Viral, Species Specificity, Gene Expression Regulation, Acetylation, Genome, Hemagglutinins, Viral, Biochemistry and Cell Biology, Medical Physiology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/8bm4x5dhTest
-
5
المؤلفون: Rabouw, Huib H, Visser, Linda J, Passchier, Tim C, Langereis, Martijn A, Liu, Fan, Giansanti, Piero, van Vliet, Arno L W, Dekker, José G, van der Grein, Susanne G, Saucedo, Jesús G, Anand, Aditya A, Trellet, Mikael E, Bonvin, Alexandre M J J, Walter, Peter, Heck, Albert J R, de Groot, Raoul J, van Kuppeveld, Frank J M, LS Virologie, dI&I I&I-1, Sub Biomol.Mass Spectrometry & Proteom., Virologie, dB&C I&I, Sub NMR Spectroscopy, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
المصدر: Nature Microbiology, 5, 1361. Nature Publishing Group
مصطلحات موضوعية: Microbiology (medical), Eukaryotic Initiation Factor-2, Immunology, Picornaviridae, Applied Microbiology and Biotechnology, Microbiology, Gene Knockout Techniques, Viral Proteins, 03 medical and health sciences, Eukaryotic translation, Stress, Physiological, Chlorocebus aethiops, Taverne, Genetics, Animals, Humans, Integrated stress response, Phosphorylation, Vero Cells, 030304 developmental biology, 0303 health sciences, eIF2, Binding Sites, biology, 030306 microbiology, Chemistry, Translation (biology), Cell Biology, Cell biology, Eukaryotic Initiation Factor-2B, Eukaryotic Cells, HEK293 Cells, eIF2B, biology.protein, Guanine nucleotide exchange factor, HeLa Cells, Protein Binding
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec28f7888dda71773841197274d03773Test
https://doi.org/10.1038/s41564-020-0759-0Test -
6
المؤلفون: Li, Zeshi, Lang, Yifei, Liu, Lin, Bunyatov, Mehman I, Sarmiento, Angelic Isaza, de Groot, Raoul J, Boons, Geert-Jan, Afd Chemical Biology and Drug Discovery, Virologie, dI&I I&I-1, Sub Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
المساهمون: Afd Chemical Biology and Drug Discovery, Virologie, dI&I I&I-1, Sub Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
المصدر: Nature Chemistry, 13(5), 496. Nature Publishing Group
مصطلحات موضوعية: Chemistry(all), General Chemical Engineering, Cell, Transfection, 010402 general chemistry, Immunofluorescence, 01 natural sciences, chemistry.chemical_compound, medicine, Humans, Receptor, Respiratory Tract Infections, Ganglioside, medicine.diagnostic_test, 010405 organic chemistry, Chemistry, Transmission (medicine), General Chemistry, Virology, N-Acetylneuraminic Acid, 0104 chemical sciences, Sialic acid, medicine.anatomical_structure, Viruses, Chemical Engineering(all), N-Acetylneuraminic acid
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1043b5a8ec4dca2e1127c21b82183ddTest
https://dspace.library.uu.nl/handle/1874/417432Test -
7
المؤلفون: Hurdiss, Daniel L, Drulyte, Ieva, Lang, Yifei, Shamorkina, Tatiana M, Pronker, Matti F, van Kuppeveld, Frank J M, Snijder, Joost, de Groot, Raoul J, Virologie, dI&I I&I-1, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
المساهمون: Virologie, dI&I I&I-1, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics
المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications, 11(1), 1. Nature Publishing Group
bioRxivمصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Glycosylation, viruses, General Physics and Astronomy, medicine.disease_cause, Esterase, Mass Spectrometry, chemistry.chemical_compound, 0302 clinical medicine, Catalytic Domain, Lectins, lcsh:Science, Coronavirus, 0303 health sciences, Multidisciplinary, biology, Virus structures, 3. Good health, Cell biology, Coronavirus Infections, Glycan, Science, Protein domain, Hemagglutinins, Viral, Context (language use), Sialic acid binding, Article, General Biochemistry, Genetics and Molecular Biology, Betacoronavirus, 03 medical and health sciences, Protein Domains, stomatognathic system, Polysaccharides, medicine, Humans, Binding site, Viral evolution, 030304 developmental biology, Binding Sites, Cryoelectron Microscopy, Lectin, Lipid bilayer fusion, General Chemistry, N-Acetylneuraminic Acid, Sialic acid, HEK293 Cells, 030104 developmental biology, chemistry, biology.protein, lcsh:Q, Viral Fusion Proteins, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3fe7fa457b04b1263a929c24fcd6a31Test
https://doi.org/10.1038/s41467-020-18440-6Test -
8دورية أكاديمية
المؤلفون: de Vries, Robert P, de Vries, Erik, Bosch, Berend Jan, de Groot, Raoul J, Rottier, Peter J M, de Haan, Cornelis A M
المساهمون: LS Virologie, Sub Medicinal Chemistry & Chemical biol.
مصطلحات موضوعية: Animals, Cell Line, Glycosylation, Hemagglutinins, Humans, Influenza A virus, Insects, Protein Binding, Protein Processing, Virus Attachment, Post-Translational
وصف الملف: image/pdf
-
9
المؤلفون: Li, Wentao, Hulswit, Ruben J G, Widjaja, Ivy, Raj, V Stalin, McBride, Ryan, Peng, Wenjie, Widagdo, W, Tortorici, M Alejandra, van Dieren, Brenda, Lang, Yifei, van Lent, Jan W M, Paulson, James C, de Haan, Cornelis A M, de Groot, Raoul J, van Kuppeveld, Frank J M, Haagmans, Bart L, Bosch, Berend-Jan, dI&I I&I-1, LS Virologie
المساهمون: dI&I I&I-1, LS Virologie, Utrecht University [Utrecht], Erasmus University Medical Center [Rotterdam] (Erasmus MC), The Scripps Research Institute [La Jolla], University of California [San Diego] (UC San Diego), University of California-University of California, Virologie Structurale - Structural Virology, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Wageningen University and Research [Wageningen] (WUR), This study is supported by TOP Project Grant 40-00812-98-13066 (to B.L.H., F.J.M.v.K., and B.-J.B.), which is funded by ZonMw (Dutch Organization for Health Research and Innovation). Research was performed as part of the Zoonoses Anticipation and Preparedness Initiative [IMI (Innovative Medicines Initiative) Grant Agreement 115760], with the assistance and financial support of the IMI and European Commission, and in-kind contributions from EFPIA (European Federation of Pharmaceutical Industries and Associations) partners. The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication., We thank Herman Egberink and Floor van der Vegt for technical assistance. We thank Monique Spronken and Debby van Riel (Department of Viroscience, Erasmus Medical Center) for providing influenza virus strain and human nose and lung tissues, respectively, The Scripps Research Institute [La Jolla, San Diego], Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Virology
المصدر: Proceedings of the National Academy of Sciences of the United States of America 114 (2017) 40
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (40), pp.E8508-E8517. ⟨10.1073/pnas.1712592114⟩
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (40), pp.E8508-E8517. ⟨10.1073/pnas.1712592114⟩
Proceedings of the National Academy of Sciences of the United States of America, 114(40), E8508. National Academy of Sciences
Proceedings of the National Academy of Sciences of the U.S.A., 114(40), E8508-E8517. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 114(40), E8508-E8517مصطلحات موضوعية: 0301 basic medicine, Camelus, Middle East respiratory syndrome coronavirus, Dipeptidyl Peptidase 4, Protein subunit, [SDV]Life Sciences [q-bio], receptor, viruses, Coronacrisis-Taverne, Laboratory of Virology, Virus Attachment, Attachment, Spike, Sialic acid binding, medicine.disease_cause, Laboratorium voor Virologie, 03 medical and health sciences, chemistry.chemical_compound, MERS-CoV, Polysaccharides, medicine, Animals, Humans, chemistry.chemical_classification, Hemagglutination assay, Multidisciplinary, biology, Mucins, spike, Virology, Sialic acid, Cell biology, 030104 developmental biology, PNAS Plus, chemistry, sialic acid, Spike Glycoprotein, Coronavirus, Middle East Respiratory Syndrome Coronavirus, Sialic Acids, biology.protein, Tissue tropism, Receptors, Virus, EPS, Coronavirus Infections, Glycoprotein, Neuraminidase, Receptor
وصف الملف: image/pdf; application/pdf; application/octet-stream
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612f258e8ced6f5a3e358c8a76d1a127Test
https://doi.org/10.1073/pnas.1712592114Test -
10
المؤلفون: Alejandra Tortorici, M, Walls, Alexandra C, Lang, Yifei, Wang, Chunyan, Li, Zeshi, Koerhuis, Danielle, Boons, Geert-Jan, Bosch, Berend-Jan, Rey, Félix A, de Groot, Raoul J, Veesler, David, LS Virologie, dI&I I&I-1, Sub Chemical Biology and Drug Discovery, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
المساهمون: Virologie Structurale - Structural Virology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Department of Biochemistry [Washington ], University of Washington [Seattle], Utrecht University [Utrecht], University of Georgia [USA], Research reported in this publication was supported by the National Institute of General Medical Sciences (R01GM120553 to D.V.), a Pew Biomedical Scholars Award (D.V.) and an Investigators in the Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund (D.V.), the Zoonoses Anticipation and Preparedness Initiative (IMI115760, F.A.R. and B.-J.B.), the Pasteur Institute (M.A.T. and F.A.R.), the Centre National de la Recherche Scientifique (F.A.R.), the LabEx Integrative Biology of Emerging Infectious Diseases (F.A.R.), the Netherlands Organization for Scientific Research (NWO TOP-PUNT 718.015.003, G.-J.B.) and CSC grant 2014-03250042 (Y.L.). This work was also partly supported by the Arnold and Mabel Beckman cryo-EM center and the Proteomics Resource (UWPR95794) at the University of Washington, and the Electron Imaging Center for NanoMachines supported by the NIH (1U24GM116792, 1S10RR23057 and 1S10OD018111), NSF (DBI-1338135) and CNSI at UCLA, We thank Y. Matsuura (Osaka University, Japan) for provision of the VSV-G pseudotyped VSVΔG/Fluc plasmids., ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), LS Virologie, dI&I I&I-1, Sub Chemical Biology and Drug Discovery, Afd Chemical Biology and Drug Discovery, Chemical Biology and Drug Discovery
المصدر: Nature structural & molecular biology
Nature Structural and Molecular Biology, 26(6), 481. Nature Publishing Group
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2019, 26 (6), pp.481-489. ⟨10.1038/s41594-019-0233-y⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (6), pp.481-489. ⟨10.1038/s41594-019-0233-y⟩
Nature Structural & Molecular Biologyمصطلحات موضوعية: Models, Molecular, MESH: Coronavirus Infections, MESH: Virus Internalization, [SDV]Life Sciences [q-bio], viruses, MESH: Spike Glycoprotein, Coronavirus, medicine.disease_cause, Coronavirus OC43, Human, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, Influenza virus C, MESH: Coronavirus OC43, Human, Coronavirus, MESH: Receptors, Cell Surface, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, MESH: Protein Multimerization, virus diseases, Transmembrane protein, 3. Good health, MESH: HEK293 Cells, Spike Glycoprotein, Coronavirus, MESH: Cryoelectron Microscopy, MESH: N-Acetylneuraminic Acid, Coronavirus Infections, MESH: Models, Molecular, Viral protein, Coronacrisis-Taverne, Hemagglutinin (influenza), Receptors, Cell Surface, Article, 03 medical and health sciences, Viral entry, medicine, Humans, Molecular Biology, 030304 developmental biology, MESH: Humans, Cryoelectron Microscopy, Virus Internalization, Virology, N-Acetylneuraminic Acid, Sialic acid, HEK293 Cells, biology.protein, Protein Multimerization, Glycoprotein, 030217 neurology & neurosurgery
وصف الملف: image/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b98687f21198f50e0d888b82868e58bTest
https://pubmed.ncbi.nlm.nih.gov/31160783Test
النص الكامل