المؤلفون: Maeda, Shoji, Koehl, Antoine, Matile, Hugues, Hu, Hongli, Hilger, Daniel, Schertler, Gebhard FX, Manglik, Aashish, Skiniotis, Georgios, Dawson, Roger JP, Kobilka, Brian K

المصدر: Nature communications. 9(1)

مصطلحات موضوعية: Humans, Macromolecular Substances, GTP-Binding Proteins, Nucleotides, Rhodopsin, Immunoglobulin Fragments, Receptors, G-Protein-Coupled, Antibodies, Monoclonal, Cryoelectron Microscopy, Crystallography, X-Ray, Protein Engineering, Signal Transduction, Binding Sites, Protein Structure, Secondary, Protein Binding, Protein Domains, Antibodies, Monoclonal, Crystallography, X-Ray, Protein Structure, Secondary, Receptors, G-Protein-Coupled

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/49b2g3h3Test

المؤلفون: Koehl, Antoine, Hu, Hongli, Maeda, Shoji, Zhang, Yan, Qu, Qianhui, Paggi, Joseph M, Latorraca, Naomi R, Hilger, Daniel, Dawson, Roger, Matile, Hugues, Schertler, Gebhard FX, Granier, Sebastien, Weis, William I, Dror, Ron O, Manglik, Aashish, Skiniotis, Georgios, Kobilka, Brian K

المصدر: Nature. 558(7711)

مصطلحات موضوعية: Animals, Mice, Inbred BALB C, Humans, Mice, Morphinans, GTP-Binding Protein alpha Subunits, Gi-Go, GTP-Binding Protein alpha Subunits, Gs, Enkephalin, Ala(2)-MePhe(4)-Gly(5)-, Receptors, Adrenergic, beta-2, Receptors, Opioid, mu, Ligands, Cryoelectron Microscopy, Binding Sites, Substrate Specificity, Female, Protein Stability, Molecular Dynamics Simulation, Inbred BALB C, GTP-Binding Protein alpha Subunits, Gi-Go, Gs, Enkephalin, Ala(2)-MePhe(4)-Gly(5)-, Receptors, Adrenergic, beta-2, Opioid, mu, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1rb3n024Test

المؤلفون: Isaikina, Polina, Tsai, Ching-Ju, Dietz, Nikolaus, Pamula, Filip, Grahl, Anne, Goldie, Kenneth N, Guixà-González, Ramon, Ferreira Da Rocha Branco, Camila Raquel, Paolini-Bertrand, Marianne, Calo, Nicolas Virgile, Cerini, Fabrice, Schertler, Gebhard F X, Hartley, Oliver, Stahlberg, Henning, Maier, Timm, Deupi, Xavier, Grzesiek, Stephan

المصدر: ISSN: 2375-2548 ; Science advances, vol. 7, no. 25 (2021) eabg8685.

مصطلحات موضوعية: info:eu-repo/classification/ddc/616.07, Chemokine CCL5 / chemistry, Chemokine CCL5 / metabolism, Cryoelectron Microscopy, Humans, Models, Molecular, Molecular Dynamics Simulation, Protein Conformation, Receptors, CCR5 / agonists, CCR5 / chemistry, CCR5 / genetics, CCR5 / metabolism, Signal Transduction, Structure-Activity Relationship

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34134983; https://archive-ouverte.unige.ch/unige:162720Test; unige:162720

الإتاحة: https://doi.org/10.1126/sciadv.abg8685Test
https://archive-ouverte.unige.ch/unige:162720Test

المؤلفون: Karathanou, Konstantina, Lazaratos, Michalis, Bertalan, Éva, Siemers, Malte, Buzar, Krzysztof, Schertler, Gebhard F X, Del Val, Coral, Bondar, Ana-Nicoleta

مصطلحات موضوعية: ACE2, Bimolecular structure, Conformational plasticity, Dynamic hydrogen-bond clusters, Hydrogen bonding, SARS-CoV-2 protein S, Algorithms, Angiotensin-Converting Enzyme 2, Betacoronavirus, COVID-19, Computational Biology, Computer Graphics, Coronavirus Infections, Humans, Models, Molecular, Pandemics, Peptidyl-Dipeptidase A, Pneumonia, Viral, Protein Binding, Protein Interaction Domains and Motifs, Protein Interaction Mapping, Protein Interaction Maps, Protein Structure, Quaternary, Secondary, SARS-CoV-2, Spike Glycoprotein, Coronavirus

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/10668/16247Test; PMC7481144; https://doi.org/10.1016/j.jsb.2020.107617Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481144/pdfTest

الإتاحة: https://doi.org/10.1016/j.jsb.2020.107617Test
http://hdl.handle.net/10668/16247Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481144/pdfTest

المؤلفون: Spillmann, Martin, Thurner, Larissa, Romantini, Nina, Zimmermann, Mirjam, Meger, Benoit, Behe, Martin, Waldhoer, Maria, Schertler, Gebhard F. X., Berger, Philipp

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 4949, p 4949 (2020)
International Journal of Molecular Sciences

مصطلحات موضوعية: Bioluminescence Resonance Energy Transfer Techniques, Receptors, Vasopressin, Arrestins, Protein Conformation, Gene Dosage, Article, Receptors, G-Protein-Coupled, lcsh:Chemistry, GPCR, Protein Domains, Genes, Reporter, Transduction, Genetic, Catalytic Domain, Humans, Luciferases, Promoter Regions, Genetic, lcsh:QH301-705.5, arrestin, receptor activation, beta-Arrestin 2, Nucleopolyhedroviruses, Recombinant Proteins, Kinetics, HEK293 Cells, lcsh:Biology (General), lcsh:QD1-999, signaling, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d54c2060b2dc060ff67c67795dce1ebcTest
https://www.mdpi.com/1422-0067/21/14/4949Test

المؤلفون: Benoit, Roger M., Frey, Daniel, Hilbert, Manuel, Kevenaar, Josta T., Wieser, Mara M., Stirnimann, Christian U., McMillan, David, Ceska, Tom, Lebon, Florence, Jaussi, Rolf, Steinmetz, Michel O., Schertler, Gebhard F X, Hoogenraad, Casper C., Capitani, Guido, Kammerer, Richard A., Sub Cell Biology, Celbiologie

المساهمون: Sub Cell Biology, Celbiologie

المصدر: Nature, 505(7481), 108. Nature Research
NATURE

مصطلحات موضوعية: Models, Molecular, Nerve Tissue Proteins, Biology, Crystallography, X-Ray, Synaptic vesicle, Structure-Activity Relationship, medicine, Humans, Botulinum Toxins, Type A, General, Receptor, Neurons, Binding Sites, Membrane Glycoproteins, Multidisciplinary, HEK 293 cells, Transporter, Fibroblast growth factor receptor 3, Endocytosis, Peptide Fragments, 3. Good health, Cell biology, Neostriatum, Transmembrane domain, HEK293 Cells, Biochemistry, Antitoxin, Acetylcholine, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6a5ea0037589d778b3aa062d6acd8cTest
https://doi.org/10.1038/nature12732Test

المؤلفون: Standfuss, Jörg, Edwards, Patricia C., D’Antona, Aaron, Fransen, Maikel, Xie, Guifu, Oprian, Daniel D., Schertler, Gebhard F. X.

مصطلحات موضوعية: Models, Molecular, Rhodopsin, Binding Sites, Rotation, Protein Conformation, Amino Acid Motifs, Water, Hydrogen Bonding, Crystallography, X-Ray, Ligands, Article, Peptide Fragments, HEK293 Cells, Retinaldehyde, Humans, Transducin, Crystallization

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::bf4506ef1facdacdee9f9520f91c143dTest
https://europepmc.org/articles/PMC3715716Test/

المؤلفون: Rasmussen, Søren Gøgsig Faarup, Choi, Hee-Jung, Rosenbaum, Daniel M, Kobilka, Tong Sun, Thian, Foon Sun, Edwards, Patricia C, Burghammer, Manfred, Ratnala, Venkata R P, Sanishvili, Ruslan, Fischetti, Robert F, Schertler, Gebhard F X, Weis, William I, Kobilka, Brian K

المصدر: Rasmussen , S G F , Choi , H-J , Rosenbaum , D M , Kobilka , T S , Thian , F S , Edwards , P C , Burghammer , M , Ratnala , V R P , Sanishvili , R , Fischetti , R F , Schertler , G F X , Weis , W I & Kobilka , B K 2007 , ' Crystal structure of the human beta2 adrenergic G-protein-coupled receptor ' , Nature , vol. 450 , no. 7168 , pp. 383-7 . https://doi.org/10.1038/nature06325Test

مصطلحات موضوعية: Adrenergic beta-2 Receptor Antagonists, Animals, Cell Line, Crystallization, Crystallography, X-Ray, Drug Inverse Agonism, Humans, Immunoglobulin Fab Fragments, Leucine, Lipids, Models, Molecular, Protein Conformation, Receptors, Adrenergic, beta-2, Rhodopsin, Spodoptera

الإتاحة: https://doi.org/10.1038/nature06325Test
https://curis.ku.dk/portal/da/publications/crystal-structure-of-the-human-beta2-adrenergic-gproteincoupled-receptorTest(0c64e5b7-36d3-4505-8f3f-fcf4551656fd).html

المؤلفون: Isaikina, Polina, Tsai, Ching-Ju, Dietz, Nikolaus, Pamula, Filip, Grahl, Anne, Goldie, Kenneth N., Guixà-González, Ramon, Branco, Camila, Paolini-Bertrand, Marianne, Calo, Nicolas, Cerini, Fabrice, Schertler, Gebhard F. X., Hartley, Oliver, Stahlberg, Henning, Maier, Timm, Deupi, Xavier, Grzesiek, Stephan

المصدر: Science Advances
Science Advances, 7 (25)

مصطلحات موضوعية: Models, Molecular, Receptors, CCR5, Protein Conformation, Cryoelectron Microscopy, rantes, virus diseases, SciAdv r-articles, dynamics, Molecular Dynamics Simulation, inhibition, stomatognathic diseases, Structure-Activity Relationship, stomatognathic system, Structural Biology, parasitic diseases, potent, Humans, amino-terminus, recognition, human activities, Chemokine CCL5, Research Articles, Research Article, Signal Transduction

وصف الملف: application/application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301ea7bbac423c72673fd88af47f376dTest
https://infoscience.epfl.ch/record/287388Test