المؤلفون: Jashelle Caga, Glenda M. Halliday, Åsa Petersén, Matthew C. Kiernan, Rebekah M. Ahmed, Sanaz Gabery

المصدر: Neuropathology and Applied Neurobiology. 47:979-989

مصطلحات موضوعية: Male, 0301 basic medicine, endocrine system, Vasopressin, medicine.medical_specialty, Histology, Neurology, Hypothalamus, Oxytocin, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, Atrophy, Physiology (medical), Internal medicine, medicine, Humans, Amyotrophic lateral sclerosis, Aged, Aged, 80 and over, Neurons, Orexins, business.industry, Amyotrophic Lateral Sclerosis, digestive, oral, and skin physiology, Fornix, Middle Aged, medicine.disease, Orexin, 030104 developmental biology, Endocrinology, nervous system, Female, Neurology (clinical), Sleep, business, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eedb0dca27e4229456cd28be082f107Test
https://doi.org/10.1111/nan.12709Test

المؤلفون: Mohammad Bsharat, Gleb Filippov, Jocelyn Y. Cheng, Gary Zammit, Nancy Hall, Margaret Moline

المصدر: Clinical Drug Investigation. 41:449-457

مصطلحات موضوعية: Adult, Male, Pyridines, 030204 cardiovascular system & hematology, Placebo, 030226 pharmacology & pharmacy, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Sleep Initiation and Maintenance Disorders, Insomnia, medicine, Humans, Pharmacology (medical), Aged, Aged, 80 and over, Sleep disorder, Cross-Over Studies, Shallow breathing, business.industry, General Medicine, Middle Aged, medicine.disease, Crossover study, Confidence interval, Pyrimidines, Pharmacodynamics, Anesthesia, Breathing, Female, Orexin Receptor Antagonists, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec32709117731d8c3a57e229a722d801Test
https://doi.org/10.1007/s40261-021-01018-5Test

المؤلفون: Anne-Laure Morel, Silvia Melzi, Roland S. Liblau, Céline Scoté-Blachon, Yves Dauvilliers, Christelle Peyron

المساهمون: Centre de recherche en neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut des Neurosciences de Montpellier - Déficits sensoriels et moteurs (INM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), CHU Montpellier, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Peyron, Christelle, APPEL À PROJETS GÉNÉRIQUE 2018 - Physiopathologie de la narcolepsie de type 1 - - NARCO-T12018 - ANR-18-CE17-0014 - AAPG2018 - VALID, Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut des Neurosciences de Montpellier (INM), ANR-18-CE17-0014,NARCO-T1,Physiopathologie de la narcolepsie de type 1(2018)

المصدر: Brain Pathology
Brain Pathology, Wiley, 2021, ⟨10.1111/bpa.13027⟩
Brain Pathology, 2022, 32 (2), pp.e13027. ⟨10.1111/bpa.13027⟩

مصطلحات موضوعية: MESH: Histamine* / metabolism, [SDV]Life Sciences [q-bio], MESH: Histidine Decarboxylase / genetics, Histidine Decarboxylase, Mixed Function Oxygenases, Mice, chemistry.chemical_compound, MESH: Narcolepsy* / genetics, 0302 clinical medicine, MESH: Orexins / metabolism, MESH: Animals, hypothalamus, 0303 health sciences, Microglia, General Neuroscience, MESH: Mixed Function Oxygenases, [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Hypothalamus, [SDV.IMM]Life Sciences [q-bio]/Immunology, Histamine, medicine.medical_specialty, [SDV.IMM] Life Sciences [q-bio]/Immunology, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, RNA, Messenger, sleep, MESH: Mice, Neuroinflammation, MESH: RNA, Messenger, Narcolepsy, 030304 developmental biology, MESH: Narcolepsy* / metabolism, Orexins, MESH: Humans, Histaminergic, medicine.disease, Pons, Orexin, Endocrinology, orexin, nervous system, chemistry, Neurology (clinical), hypocretin, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4490e3482708d0b4df213bb72bef01faTest
https://doi.org/10.1111/bpa.13027Test

المؤلفون: Manish K. Jha

المصدر: International Journal of Neuropsychopharmacology

مصطلحات موضوعية: Adult, AcademicSubjects/MED00415, Orexin hypocretin, Bioinformatics, Placebo, Regular Research Articles, mental disorders, orexin-2, medicine, Insomnia, Humans, Pharmacology (medical), Pyrroles, Adjunctive therapy, Depression (differential diagnoses), Pharmacology, Depressive Disorder, Major, major depressive disorder, business.industry, AcademicSubjects/SCI01870, Orexin Receptor Antagonists, Triazoles, medicine.disease, Orexin, Psychiatry and Mental health, Pyrimidines, Antidepressant, Major depressive disorder, seltorexant, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b678e2f68fa36898e91be01bb6bad97Test
https://pubmed.ncbi.nlm.nih.gov/34324636Test

المؤلفون: Mike Ufer, Kerri A. Schoedel, Debra Kelsh, Jasper Dingemanse

المصدر: Sleep. 45

مصطلحات موضوعية: Zolpidem, Pyrrolidines, Lemborexant, Pharmacology, Placebo, Drug Users, Double-Blind Method, Pharmacokinetics, Physiology (medical), Humans, Hypnotics and Sedatives, Medicine, Cross-Over Studies, business.industry, Suvorexant, Imidazoles, Azepines, Triazoles, Crossover study, Orexin receptor, Pharmacodynamics, Orexin Receptor Antagonists, Neurology (clinical), business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36aad227cd4f79d02ddddcabe0f64e8Test
https://doi.org/10.1093/sleep/zsab224Test

المؤلفون: Tingting Mou, Rolf Fronczek, Dick F. Swaab, Kangyu Jin, Jinfeng Duan, Haimei Li, Weijuan Xu, Ai-Min Bao, Jing Lu, Jin-Hui Li, Manli Huang

المساهمون: Netherlands Institute for Neuroscience (NIN)

المصدر: Schizophrenia bulletin, 47, 1310-1319. Oxford University Press
Schizophr Bull
Schizophrenia Bulletin, 47(5), 1310-1319. OXFORD UNIV PRESS

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Prefrontal Cortex, superior frontal gyrus, Neurotransmission, cerebrospinal fluid, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Sex Factors, Orexin Receptors, Internal medicine, mental disorders, medicine, Humans, hypothalamus, Receptor, orexin, hypocretin receptor, plasma, Orexins, hypocretin receptor, business.industry, Middle Aged, medicine.disease, 030227 psychiatry, Orexin, schizophrenia, Psychiatry and Mental health, Endocrinology, Superior frontal gyrus, orexin, nervous system, Schizophrenia, Hypothalamus, Female, Autopsy, hypocretin, business, 030217 neurology & neurosurgery, psychological phenomena and processes, Hypocretin orexin, Regular Articles

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7365773eafaeccb2f576b7012f99e5ffTest
https://hdl.handle.net/1887/3248773Test

المؤلفون: Yuxiu Shi, Dan Han, Fang Han

المصدر: The Journal of comparative neurologyREFERENCES. 530(3)

مصطلحات موضوعية: Male, medicine.medical_specialty, Elevated plus maze, Prefrontal Cortex, Biology, Anxiety, behavioral disciplines and activities, Open field, Stress Disorders, Post-Traumatic, Orexin-A, Orexin Receptors, Internal medicine, mental disorders, medicine, Animals, Humans, Rats, Wistar, Orexins, Depression, General Neuroscience, digestive, oral, and skin physiology, Traumatic stress, Anhedonia, Orexin receptor, Orexin, Rats, Disease Models, Animal, Endocrinology, nervous system, medicine.symptom, psychological phenomena and processes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288aef9f75e096b14c9beecca1106b49Test
https://pubmed.ncbi.nlm.nih.gov/34387361Test

المؤلفون: Tetsuya Shiga, Yusuke Osakabe, Sho Horikoshi, Hiroshi Hoshino, Hirooki Yabe, Kazuko Kanno, Itaru Miura, Haruka Ochiai

المصدر: Journal of psychopharmacology (Oxford, England). 35(12)

مصطلحات موضوعية: Adult, Male, Side effect, medicine.drug_class, Mismatch negativity, Pharmacology, Lorazepam, 03 medical and health sciences, Benzodiazepines, Young Adult, 0302 clinical medicine, Discrimination, Psychological, Medicine, Humans, Pharmacology (medical), Cognitive Dysfunction, 030212 general & internal medicine, Cognitive decline, Benzodiazepine, business.industry, Suvorexant, Antagonist, Electroencephalography, Azepines, Triazoles, Event-Related Potentials, P300, Orexin receptor, Psychiatry and Mental health, Tolerability, Auditory Perception, Evoked Potentials, Auditory, Female, Orexin Receptor Antagonists, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67dee48dc49baa60fe2b41d5127f1512Test
https://pubmed.ncbi.nlm.nih.gov/34330170Test

المؤلفون: Fabio Arturo Iannotti, Fabiana Piscitelli, Pietro Amodeo, Rosa Maria Vitale, Vincenzo Di Marzo, Ranjev Savopoulos, Luigia Cristino, Aniello Schiano Moriello, Royston A. Gray, Luciano De Petrocellis, Lea Tunisi

المصدر: Biomolecules, Vol 11, Iss 1134, p 1134 (2021)
Biomolecules
Volume 11
Issue 8
Biomolecules 11 (2021). doi:10.3390/biom11081134
info:cnr-pdr/source/autori:Vitale R.M.; Iannotti F.A.; Moriello A.S.; Tunisi L.; Piscitelli F.; Savopoulos R.; Cristino L.; De Petrocellis L.; Amodeo P.; Gray R.; Di Marzo V./titolo:Identification and characterization of cannabidiol as an ox1r antagonist by computational and in vitro functional validation/doi:10.3390%2Fbiom11081134/rivista:Biomolecules/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11

مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Gene Expression, Pharmacology, Biochemistry, Radioligand Assay, cannabidiol, 0302 clinical medicine, Transgenes, Receptor, media_common, Chemistry, calcium mobilization assay, Ligand (biochemistry), calcium influx assay, Orexin receptor, QR1-502, Molecular Imaging, Molecular Docking Simulation, calcium imaging, Anticonvulsants, Orexin Receptor Antagonists, Protein Binding, medicine.drug, Drug, orexin receptors, OX1R, media_common.quotation_subject, CHO Cells, Microbiology, Article, 03 medical and health sciences, Cricetulus, medicine, Animals, Humans, Protein Interaction Domains and Motifs, Molecular Biology, Orexins, Binding Sites, Antagonist, antagonist, molecular docking, In vitro, molecular dynamics, Orexin, Kinetics, 030104 developmental biology, Anti-Anxiety Agents, Calcium, Protein Conformation, beta-Strand, Cannabidiol, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774e5847c77075e8bf23ab08f2e5ffadTest
https://www.mdpi.com/2218-273X/11/8/1134Test

المؤلفون: William Stoops, Justin C. Strickland, Kevin W. Hatton, Lon R. Hays, Abner O. Rayapati, Joshua A. Lile, Craig R. Rush

المصدر: Pharmacology Biochemistry and Behavior. 220:173466

مصطلحات موضوعية: Pharmacology, History, Orexins, Polymers and Plastics, Clinical Biochemistry, Azepines, Triazoles, Toxicology, Biochemistry, Industrial and Manufacturing Engineering, Behavioral Neuroscience, Cocaine, Orexin Receptors, Animals, Humans, Orexin Receptor Antagonists, Business and International Management, Biological Psychiatry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c0b1724bdf9a32e3407294960b420eTest
https://doi.org/10.1016/j.pbb.2022.173466Test