يعرض 1 - 10 نتائج من 22 نتيجة بحث عن '"Of - 5 – 4"', وقت الاستعلام: 0.92s تنقيح النتائج
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    المساهمون: UCL - SSS/LDRI - Louvain Drug Research Institute, Groupe de Recherche Interdiscipinaire Innovation et Optimisation Thérapeutique - EA 4481 (GRIIOT), Université de Lille, Droit et Santé, Institut pour la Recherche sur le Cancer de Lille (U837 INSERM - IRCL), Institut pour la recherche sur le cancer de Lille [Lille] (IRCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche Jean-Pierre AUBERT - Neurosciences et Cancer -JPArc [Lille], Institut de Chimie Pharmaceutique Albert Lespagnol (ICPAL), Laboratorio di Chimica Bioinorganica (LCBI), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Laboratorio di Chimica Bioinorganica, Université de Namur [Namur] (UNamur), EA 4481 Groupe de Recherche Interdiscipinaire (GRIIOT), Faculté des Sciences Pharmaceutiques et Biologiques, Università degli Studi di Firenze = University of Florence [Firenze], Université de Namur [Namur], Plasticité Cellulaire et Cancer (CPAC) - U908 (CPAC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Catholique de Louvain (UCL), Génétique moléculaire et approches thérapeutiques des hémopathies malignes, IRCL-Institut National de la Santé et de la Recherche Médicale (INSERM)

    المصدر: Bioorganic & Medicinal Chemistry
    Bioorganic & Medicinal Chemistry : the tetrahedron journal for research at the interface of chemistry and biology, Vol. 21, no. 6, p. 1451-1464 (2013)
    Bioorganic & Medicinal Chemistry; Vol 21
    Bioorganic and Medicinal Chemistry
    Bioorganic and Medicinal Chemistry, Elsevier, 2013, 21 (6), pp.1451-1464. ⟨10.1016/j.bmc.2012.10.029⟩

    مصطلحات موضوعية: 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (4 bromophenyl) 1h pyrazole, Carbonate dehydratase ix inhibitor, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (2 phenantryl) 1h pyrazole, Unclassified drug, Clinical Biochemistry, Cell, Pharmaceutical Science, Drug structure, Antiproliferative activity, 1 (3 aminosulfonylphenyl) 3 hydroxymethyl 5 phenyl 1h pyrazole, 01 natural sciences, Biochemistry, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (4 methoxyphenyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 4 hydroxymethyl 5 (2 naphthyl) 1h pyrazole, Breast cancer, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (5 bromo 6 methoxynaphtalen 2 yl) 1h pyrazole, Catalytic Domain, Drug Discovery, Cytotoxicity, Hypoxia, Carbonic Anhydrase Inhibitors, ComputingMilieux_MISCELLANEOUS, Enzyme active site, Carbonic Anhydrases, chemistry.chemical_classification, 0303 health sciences, Sulfonamides, Carbonic anhydrase, biology, Chemistry, Aryl sulfonamide inhibitors, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (2 methoxyphenyl) 1h pyrazole, Carbonate dehydratase IX, 3. Good health, 1 (3 aminosulfonylphenyl) 3 hydroxymethyl 5 (6 methoxy 2 naphthalenyl) 1h pyrazole, Molecular Docking Simulation, Enzyme inhibition, medicine.anatomical_structure, Drug screening, Drug selectivity, Molecular Medicine, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (6 methoxynaphtalen 2 yl) 1h pyrazole, Simulation, medicine.drug, 1 (4 aminosulfonylphenyl) 5 hydroxymethyl 3 phenyl 1h pyrazole, Protein Binding, 1 (3 aminosulfonylphenyl) 3 hydroxymethyl 5 naphthyl 1h pyrazole, Drug cytotoxicity, 1 (4 aminosulfonylphenyl) 5 hydroxymethyl 3 (2 naphthyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 pyridinyl 1h pyrazole, Drug binding, Sulfonamide, Article, Molecular model, 03 medical and health sciences, Drug synthesis, Structure-Activity Relationship, Drug potency, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Antigens, Neoplasm, Cell Line, Tumor, medicine, Humans, Doxorubicin, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (1 naphthyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 4 hydroxymethyl 5 phenyl 1h pyrazole, Carbonic Anhydrase IX, Molecular Biology, 1 (4 aminosulfonylphenyl) 3 hydroxyethyl 5 phenyl 1h pyrazole, 030304 developmental biology, Cell Proliferation, 1 (4 aminosulfonylphenyl) 4 hydroxymethyl 5 (6 methoxy 2 naphtalenyl) 1h pyrazole, Carbonate dehydratase inhibitor, Cell strain MDA MB 231, Binding Sites, 010405 organic chemistry, Organic Chemistry, Active site, In vitro, 0104 chemical sciences, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (2 naphthyl) 1h pyrazole, Kinetics, Enzyme, Binding kinetics, Tumor progression, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (4 tolyl) 1h pyrazole, Pyrazole, biology.protein, Pyrazoles, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 (3 methoxyphenyl) 1h pyrazole, 1 (4 aminosulfonylphenyl) 3 hydroxymethyl 5 phenyl 1h pyrazole, Cell line, 4 (5 aryl 2 hydroxymethyl pyrazol 1 yl)benzenesulfonamide

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    المصدر: Medicinal Chemistry. 4:110-115

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    المساهمون: Cazzola, M., Matera, Maria Gabriella, Rogliani, P., Page, C.

    المصدر: Trends in Pharmacological Sciences. 28:544-550

    مصطلحات موضوعية: muscle atrophy, Pathology, antioxidant, Heart disease, Phosphodiesterase Inhibitors, Settore MED/10 - Malattie dell'Apparato Respiratorio, gastrointestinal symptom, Angiotensin-Converting Enzyme Inhibitors, heart disease, oxygen therapy, systemic disease, heparin, Toxicology, Bioinformatics, Systemic inflammation, Antioxidants, PPAR agonist, hydroxymethylglutaryl coenzyme A reductase inhibitor, rosiglitazone, low drug dose, Pulmonary Disease, Chronic Obstructive, irbesartan, Adrenal Cortex Hormones, dipeptidyl carboxypeptidase inhibitor, pioglitazone, simvastatin, COPD, combination chemotherapy, beta 2 adrenergic receptor stimulating agent, Pulmonary inflammation, 4 (4 fluorophenyl) 2 (4 methylsulfinylphenyl) 5 (4 pyridyl)imidazole, 4 [4 (4 fluorophenyl) 1 (3 phenylpropyl) 5 (4 pyridinyl) 1h imidazol 2 yl] 3 butyn 1 ol, 4 [4 (4 fluorophenyl) 5 (2 methoxy 4 pyrimidinyl) 1 imidazolyl]cyclohexanol, acetylcysteine, angiotensin 2 receptor antagonist, bronchodilating agent, corticosteroid, doramapimod, enoxaparin, etanercept, glutathione derivative, glycosaminoglycan, infliximab, mevinolin, muscarinic receptor blocking agent, phosphodiesterase IV inhibitor, selenium derivative, superoxide dismutase, theophylline, antiinflammatory activity, atherosclerosis, cardiovascular risk, chronic obstructive lung disease, comorbidity, corticosteroid therapy, disease control, drug activity, drug efficacy, drug fatality, heart arrhythmia, human, nonhuman, pneumonia, priority journal, pulmonary rehabilitation, review, smoking cessation, thrombosis, Bronchodilator Agents, Drug Therapy, Combination, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Inflammation, PPAR gamma, Smoking Cessation, medicine.anatomical_structure, Combination, medicine.symptom, Chronic Obstructive, medicine.medical_specialty, chronic obstructive pulmonary disease, statins, Pulmonary Disease, Drug Therapy, ACE inhibitor, medicine, Pharmacology, Lung, Angiotensin II receptor type 1, business.industry, medicine.disease, inflammation, business

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    المساهمون: Torcia, M, De Chiara, G, Nencioni, L, Ammendola, S, Labardi, D, Lucibello, M, Rosini, P, Marlier, Ln, Bonini, P, Dello Sbarba, P, Palamara, At, Zambrano, Nicola, Russo, Tommaso, Garaci, E, Cozzolino, F.

    المصدر: 276 (2001): 39027–39036.
    info:cnr-pdr/source/autori:Torcia M., De Chiara G., Nencioni L., Ammendola S., Labardi D., Lucibello M., Rosini P., Marlier L.NJL., Bonini P., Dello Sbarba P.D., Palamara A.T., Zambrano N., Russo T., Garaci E., Cozzolino F./titolo:Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release./doi:/rivista:/anno:2001/pagina_da:39027/pagina_a:39036/intervallo_pagine:39027–39036/volume:276
    Università degli studi di Firenze-IRIS

    مصطلحات موضوعية: mitogen activated protein kinase p38, MAPK/ERK pathway, MAP Kinase Kinase 4, Pyridines, Apoptosis, animal cell, stress activated protein kinase, Biochemistry, Cytosol, mitochondrion, Enzyme Inhibitors, Cells, Cultured, serodiagnosis, Cultured, mitogen activated protein kinase, phosphorylation, Kinase, Cytochrome c, protein function, cytochrome c, priority journal, protein transport, Bioassay, Cells, Enzymes, Mutagenesis, Nerve growth factor (NGF), 4 (4 fluorophenyl) 2 (4 methylsulfinylphenyl) 5 (4 pyridyl)imidazole, Janus kinase, nerve growth factor, protein bcl 2, serine, synaptophysin, threonine, DNA fragment, enzyme inhibitor, imidazole derivative, mitogen activated protein kinase kinase, mitogen activated protein kinase kinase 4, pyridine derivative, recombinant protein, apoptosis, article, autocrine effect, B lymphocyte, cell survival, controlled study, enzyme activation, enzyme inactivation, human, human cell, immunoprecipitation, in vitro study, in vivo study, memory cell, molecular biology, nonhuman, protein phosphorylation, protein secretion, animal, cell culture, cell nucleus, chemistry, cytosol, drug antagonism, fluorescence microscopy, immunological memory, metabolism, pathology, physiology, protein binding, rat, time, Animalia, Janus, Animals, B-Lymphocytes, Cell Nucleus, Cytochrome c Group, DNA Fragmentation, Humans, Imidazoles, Immunologic Memory, JNK Mitogen-Activated Protein Kinases, Microscopy, Fluorescence, Mitochondria, Mitogen-Activated Protein Kinase Kinases, Mitogen-Activated Protein Kinases, Nerve Growth Factor, p38 Mitogen-Activated Protein Kinases, Phosphorylation, Precipitin Tests, Protein Binding, Protein Transport, Proto-Oncogene Proteins c-bcl-2, Rats, Recombinant Proteins, Serine, Threonine, Time Factors, p38 mitogen-activated protein kinases, Fluorescence, Protein kinase A, Molecular Biology, NGF, apoptosis, B lymphocytes, Microscopy, biology, Settore MED/07 - Microbiologia e Microbiologia Clinica, Autocrine signalling, Cell Biology, Molecular biology, Nerve growth factor, biology.protein

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    المساهمون: Uludağ Üniversitesi/Veterinerlik Fakültesi/Biyokimya Anabilim Dalı., Yalçın, Abdullah, ABI-4164-2020, A-5261-2016

    المصدر: Oncogene

    مصطلحات موضوعية: Cancer Research, Choline kinase, Unclassified drug, Mouse, Biochemistry & molecular biology, Signal transduction, Mitogen activated protein kinase, Steady state, Computational biology, Hela cells, chemistry.chemical_compound, Mice, 0302 clinical medicine, n (3,5 dimethylphenyl) 2 [[5 (4 ethylphenyl) 1h 1,2,4 triazol 3 yl]sulfanyl] acetamide, Computer model, Acetamides, Phosphatidic acid, Second messenger, Cancer inhibition, Enzyme activity, Phosphorylation, Mitogen-activated protein kinases, Cell proliferation, Phosphocholine, Priority journal, Phosphatidic-acid, 0303 health sciences, Extracellular signal-regulated MAP kinases, Genetics & heredity, Enzyme inhibitors, Molecular interaction, Enzyme inhibitor, 3. Good health, Cell biology, Biochemistry, Oncology, Protein conformation, 030220 oncology & carcinogenesis, Female, Models, molecular, Phosphatidylinositol 3-kinases, Choline Kinase, Phosphoethanolamine, N Acetylaspartic Acid, Xenograft model antitumor assays, Human, Prostate-cancer, Phosphorylcholine, Choline kinase alpha, Biology, Protein targeting, Article, 03 medical and health sciences, Protein kinase B, Genetics, Chemotherapy, Animals, Humans, Animal model, Animal experiment, Protein kinase A, Molecular Biology, Lung tumor, 030304 developmental biology, MAP kinase kinase kinase, Inhibitors, In silico, Phospholipase-D, Proto-oncogene proteins c-akt, Ras activation, Triazoles, Nonhuman, Raf-1, Actins, MAP kinase signaling system, Proto-oncogene proteins p21(ras), Phosphatidylcholine, Metabolism, chemistry, P-31, Human cell, Breast-cancer-cells, Protein expression, Cyclin-dependent kinase 9, Tumor xenograft, Cell membrane, Controlled study, Phosphatidylinositol 3 kinase, Growth-factors

    وصف الملف: application/pdf

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    المصدر: Lab. Invest. 2010;90(7):1049-1059
    Biblioteca Digital (UBA-FCEN)
    Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
    instacron:UBA-FCEN

    وصف الملف: application/pdf

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    المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/ İç Hastalıkları Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı., Uludağ Üniversitesi/Tıp Fakültesi/Genetik Anabilim Dalı., Ali, Rıdvan, Özkalemkaş, Fahir, Kimya, Yalçın, Köksal, Nligün, Özkocaman, Vildan, Gülten, Tuna, Yorulmaz, Hakan, Tunalı, Ahmet Semih, AAH-1854-2021, AAG-8495-2021, AAG-8393-2021