المؤلفون: Robyn Fong, Tiffany K Koyano, Trieu Nguyen, Manabu Nagao, Ramen Kundu, Robert C. Wirka, Milos Pjanic, John A. Coller, Rui Chang, Y. Joseph Woo, Stephen B. Montgomery, Juyong Brian Kim, Michelle D. Tallquist, Clint L. Miller, Boxiang Liu, Joseph C. Wu, Kuixi Zhu, Melissa Alamprese, David T. Paik, Thomas Quertermous, Dhananjay Wagh

المصدر: Nature medicine

مصطلحات موضوعية: 0301 basic medicine, Vascular smooth muscle, Myocytes, Smooth Muscle, Cell, Coronary Artery Disease, Biology, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, Transcriptome, Mice, 03 medical and health sciences, 0302 clinical medicine, Single-cell analysis, Basic Helix-Loop-Helix Transcription Factors, medicine, Animals, Humans, Myocyte, Macrophage, Cells, Cultured, Sequence Analysis, RNA, Fibrous cap, Osteoprotegerin, General Medicine, Phenotype, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, cardiovascular system, Single-Cell Analysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202720aa41b867815d5ba710b13098eaTest
https://doi.org/10.1038/s41591-019-0512-5Test

المؤلفون: Dharini Iyer, Hunter B. Fraser, Paul Cheng, Michael Dacre, Quanyi Zhao, Milos Pjanic, Trieu Nguyen, Boxiang Liu, Thomas Quertermous, Juyong Brian Kim, Robert C. Wirka

المصدر: Genome Biology, Vol 21, Iss 1, Pp 1-23 (2020)
Genome Biology

مصطلحات موضوعية: Quantitative trait locus, lcsh:QH426-470, Myocytes, Smooth Muscle, Primary Cell Culture, Quantitative Trait Loci, Coronary Disease, Genome-wide association study, Computational biology, Biology, Coronary artery disease, Muscle, Smooth, Vascular, Epigenesis, Genetic, Transforming Growth Factor beta1, Genome editing, Basic Helix-Loop-Helix Transcription Factors, Humans, Smad3 Protein, Epigenetics, lcsh:QH301-705.5, Gene, Transcription factor, TCF21, Chromosomal looping, Chromatin accessibility, Research, Coronary Vessels, Human genetics, Fibronectins, Chromatin, lcsh:Genetics, Smooth muscle cells, lcsh:Biology (General)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a024b64fd4585cc08c45769818aeecfcTest
https://doi.org/10.1186/s13059-020-02049-5Test

المؤلفون: Stanislao Travisano, Paul Cheng, Thomas Quertermous, Ramendra K. Kundu, Trieu Nguyen, Robert C. Wirka, Milos Pjanic, Quanyi Zhao, Juyong Brian Kim, Manabu Nagao

المصدر: Circulation
Circulation, vol 142, iss 6

مصطلحات موضوعية: Aging, muscle, Cellular differentiation, Cardiorespiratory Medicine and Haematology, Inbred C57BL, Cardiovascular, Mice, 0302 clinical medicine, vascular, Smooth muscle, Smooth Muscle, Receptors, 2.1 Biological and endogenous factors, Medicine, animal, Cells, Cultured, Plaque, Atherosclerotic, Mice, Knockout, 0303 health sciences, Cultured, biology, Cell Differentiation, musculoskeletal system, Coronary Vessels, Plaque, Atherosclerotic, Cell biology, Heart Disease, Aryl Hydrocarbon, vascular calcification, Public Health and Health Services, cardiovascular system, Cardiology and Cardiovascular Medicine, Chondrogenesis, smooth, Cells, Knockout, Clinical Sciences, Myocytes, Smooth Muscle, Article, models, 03 medical and health sciences, Physiology (medical), Genetics, Animals, Humans, Vascular calcification, Transcription factor, Collagen Type II, Heart Disease - Coronary Heart Disease, 030304 developmental biology, Cell Proliferation, Myocytes, business.industry, Environmental Exposure, Atherosclerosis, Aryl hydrocarbon receptor, Alkaline Phosphatase, Mice, Inbred C57BL, Cardiovascular System & Hematology, Receptors, Aryl Hydrocarbon, biology.protein, genetic, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96018cfd10cd2479ec913932267ffda5Test
https://europepmc.org/articles/PMC8066499Test/

المؤلفون: Sanjay Sinha, Felipe Serrano, Marie A Guerraty, Thomas Quertermous, Yi-An Ko, Milos Pjanic, Wei Zhao, Scott Norton, Yoseph Barash, Daniel J. Rader, Ulf Hedin, John Pluta, Robert C. Wirka, Christopher D. Brown, Trieu Nguyen, Sylvia T. Nurnberg, Ljubica Perisic, Stephanie Testa, Ting Wang, Susannah Elwyn, H. Shanker Rao, YoSon Park

المساهمون: Nurnberg, Sylvia T. [0000-0002-0869-484X], Guerraty, Marie A. [0000-0002-0766-1253], Wirka, Robert C. [0000-0001-9131-9508], Rao, H. Shanker [0000-0001-6827-1470], Norton, Scott [0000-0002-1366-0628], Pluta, John [0000-0002-8941-6242], Zhao, Wei [0000-0002-8301-9297], Park, YoSon [0000-0002-0465-4744], Nguyen, Trieu [0000-0001-5647-1301], Hedin, Ulf [0000-0001-9212-3945], Barash, Yoseph [0000-0003-3005-5048], Brown, Christopher D. [0000-0002-3785-5008], Quertermous, Thomas [0000-0002-7645-9067], Rader, Daniel J. [0000-0002-9245-9876], Apollo - University of Cambridge Repository, Nurnberg, Sylvia T [0000-0002-0869-484X], Guerraty, Marie A [0000-0002-0766-1253], Wirka, Robert C [0000-0001-9131-9508], Rao, H Shanker [0000-0001-6827-1470], Brown, Christopher D [0000-0002-3785-5008], Rader, Daniel J [0000-0002-9245-9876]

المصدر: PLoS Genetics
PLoS Genetics, Vol 16, Iss 1, p e1008538 (2020)

مصطلحات موضوعية: Cancer Research, Gene Expression, Genome-wide association study, QH426-470, Smooth Muscle Cells, Vascular Medicine, Coronary artery disease, 0302 clinical medicine, Animal Cells, Medicine and Health Sciences, Coronary Heart Disease, Genetics (clinical), Coronary Arteries, Cells, Cultured, 0303 health sciences, Nuclear Proteins, Genomics, Arteries, Coronary Vessels, medicine.anatomical_structure, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Anatomy, Cellular Types, Research Article, Protein Binding, animal structures, Myocytes, Smooth Muscle, Cardiology, Muscle Tissue, Locus (genetics), Single-nucleotide polymorphism, Biology, Quantitative trait locus, Polymorphism, Single Nucleotide, 03 medical and health sciences, medicine, Genome-Wide Association Studies, Genetics, Humans, Vascular Diseases, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Muscle Cells, RBPJ, Twist-Related Protein 1, Colocalization, Biology and Life Sciences, Computational Biology, Endothelial Cells, Human Genetics, Cell Biology, medicine.disease, Genome Analysis, Coronary arteries, Biological Tissue, Genetic Loci, Cancer research, Cardiovascular Anatomy, Blood Vessels, Endothelium, Vascular, Transcriptome, 030217 neurology & neurosurgery

وصف الملف: text/xml; application/zip; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a09ef6a67d3e70f2be758fa302b511Test
http://europepmc.org/articles/PMC6975560Test

المؤلفون: Manabu, Nagao, Qing, Lyu, Quanyi, Zhao, Robert C, Wirka, Joetsaroop, Bagga, Trieu, Nguyen, Paul, Cheng, Juyong Brian, Kim, Milos, Pjanic, Joseph M, Miano, Thomas, Quertermous

المصدر: Circ Res

مصطلحات موضوعية: Serum Response Factor, Binding Sites, Base Sequence, Myocytes, Smooth Muscle, Nuclear Proteins, Cell Differentiation, Coronary Artery Disease, Article, HEK293 Cells, Gene Expression Regulation, Basic Helix-Loop-Helix Transcription Factors, Trans-Activators, Humans, Genetic Predisposition to Disease, Promoter Regions, Genetic, Cells, Cultured, Protein Binding, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::e1ae4228410655f44a27e4560bf132b1Test
https://pubmed.ncbi.nlm.nih.gov/32078454Test

المؤلفون: Erik Ingelsson, Casimiro Castillejo-López, Abhiram Rao, Joshua W. Knowles, Naomi L. Cook, Susanne Hetty, Milos Pjanic, Andrew G. Emmerich, Thomas Quertermous

المصدر: BMC Endocrine Disorders
BMC Endocrine Disorders, Vol 19, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: SPRY2, 0301 basic medicine, endocrine system, Cell- och molekylärbiologi, Endocrinology, Diabetes and Metabolism, Glucose uptake, Endocrinology and Diabetes, lcsh:Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, 0302 clinical medicine, Insulin resistance, Downregulation and upregulation, Lipid droplet, Type 2 diabetes mellitus, Humans, Medicine, Obesity, Phosphorylation, Protein kinase A, Protein kinase B, Glucose metabolism, lcsh:RC648-665, Kinase, business.industry, Gene Expression Profiling, Lipogenesis, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Lipid metabolism, Hep G2 Cells, Lipid Droplets, General Medicine, medicine.disease, Cell biology, Glucose, 030104 developmental biology, 030220 oncology & carcinogenesis, Endokrinologi och diabetes, Hepatocytes, CRISPR-Cas Systems, CRISPR-Cas9, business, Cell and Molecular Biology, Signal Transduction, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a7319345e45d8d03e4d9c74a997dcaTest
https://doi.org/10.1186/s12902-019-0442-8Test

المؤلفون: Manabu Nagao, Quanyi Zhao, Trieu Nguyen, Paul Cheng, Thomas Quertermous, Juyong Brian Kim, Clint L. Miller, Milos Pjanic, Robert C. Wirka

المصدر: Genome medicine, vol 11, iss 1
Genome Medicine
Genome Medicine, Vol 11, Iss 1, Pp 1-18 (2019)

مصطلحات موضوعية: 0301 basic medicine, Epigenomics, lcsh:Medicine, Coronary Artery Disease, Cardiovascular, Epigenesis, Genetic, 0302 clinical medicine, Transcription (biology), Gene expression, Basic Helix-Loop-Helix Transcription Factors, 2.1 Biological and endogenous factors, Aetiology, Genetics (clinical), Cells, Cultured, Genetics, Cultured, Chromatin, Histone, Heart Disease, 030220 oncology & carcinogenesis, Molecular Medicine, Histone acetyltransferase, Transcription, lcsh:QH426-470, Cells, Clinical Sciences, Biology, Chromatin remodeling, 03 medical and health sciences, Genetic, Humans, Epigenetics, Smad3 Protein, Molecular Biology, Gene, Transcription factor, Heart Disease - Coronary Heart Disease, Cyclin-Dependent Kinase Inhibitor p15, TCF21, Research, lcsh:R, Human Genome, Chromatin Assembly and Disassembly, AP-1, Atherosclerosis, Transcription Factor AP-1, Deacetylase, lcsh:Genetics, 030104 developmental biology, HEK293 Cells, biology.protein, Generic health relevance, Epigenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b989ab20add3eeddf2662f3848633381Test
https://escholarship.org/uc/item/5x1301sxTest

المؤلفون: Ting Wang, Michael Snyder, Thomas Quertermous, Trieu Nguyen, Stephen B. Montgomery, Ulf Hedin, Oscar Franzén, Arno Ruusalepp, Vivek Nanda, Eric E. Schadt, Johan Björkegren, Milos Pjanic, Lijiang Ma, Boxiang Liu, Simon Koplev, Clint L. Miller, Nicholas J. Leeper, Ljubica Perisic Matic

المصدر: PLoS Genetics
PLoS Genetics, Vol 14, Iss 11, p e1007755 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Linkage disequilibrium, Becaplermin, Gene Expression, Muscle Proteins, Genome-wide association study, Coronary Artery Disease, QH426-470, Vascular Medicine, Biochemistry, Autoantigens, Linkage Disequilibrium, Mice, Risk Factors, Medicine and Health Sciences, Coronary Heart Disease, Small interfering RNAs, Genetics (clinical), Cells, Cultured, Epigenomics, Genetics, Chromosome Biology, Forkhead Box Protein O3, Models, Cardiovascular, Chromosome Mapping, Genomics, Arteries, Phenotype, Coronary Vessels, Chromatin, 3. Good health, Nucleic acids, Gene Knockdown Techniques, Epigenetics, Anatomy, Research Article, Protein Binding, Myocytes, Smooth Muscle, Quantitative Trait Loci, Cardiology, Locus (genetics), Mice, Transgenic, Biology, Molecular Genetics, 03 medical and health sciences, Genome-Wide Association Studies, Animals, Humans, Allele, Non-coding RNA, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Alleles, Binding Sites, 030102 biochemistry & molecular biology, Biology and Life Sciences, Computational Biology, Human Genetics, Cell Biology, Genome Analysis, Gene regulation, Cytoskeletal Proteins, Disease Models, Animal, 030104 developmental biology, Genetic Loci, Expression quantitative trait loci, Cardiovascular Anatomy, Blood Vessels, RNA, Chromatin immunoprecipitation, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fed058ccde82957480120873b6ac84Test
http://europepmc.org/articles/PMC6268002Test

المؤلفون: Ameay Naravane, Dharini Iyer, Boxiang Liu, Quanyi Zhao, Paul Cheng, Trieu Nguyen, Juyong Brian Kim, Clint L. Miller, Milos Pjanic, Manabu Nagao, Robert C. Wirka, Thomas Quertermous

المصدر: PLoS Genetics, Vol 14, Iss 10, p e1007681 (2018)
PLoS Genetics

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cell signaling, Gene Expression, Coronary Artery Disease, Signal transduction, Vascular Medicine, Biochemistry, Muscle, Smooth, Vascular, Transforming Growth Factor beta, Gene expression, Basic Helix-Loop-Helix Transcription Factors, Medicine and Health Sciences, Coronary Heart Disease, Small interfering RNAs, Genetics (clinical), Regulation of gene expression, Signaling cascades, Cell Differentiation, Genomics, Phenotype, 3. Good health, Cell biology, Chromatin, Nucleic acids, Research Article, lcsh:QH426-470, Smooth muscle cell differentiation, SMAD signaling, Primary Cell Culture, Cardiology, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, Genetics, Genome-Wide Association Studies, Humans, Genetic Predisposition to Disease, Smad3 Protein, Non-coding RNA, Molecular Biology, Transcription factor, Gene, Ecology, Evolution, Behavior and Systematics, Reporter gene, Binding Sites, Biology and Life Sciences, Computational Biology, Epistasis, Genetic, Human Genetics, Genome Analysis, Gene regulation, lcsh:Genetics, 030104 developmental biology, TGF-beta signaling cascade, Genetic Loci, RNA, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4227ad9301a851f066824899f6ccc19eTest
http://europepmc.org/articles/PMC6198989?pdf=renderTest

المؤلفون: Stephen B. Montgomery, Ting Wang, Michael J. Gloudemans, Susannah Elwyn, Sylvia T. Nurnberg, Trieu Nguyen, Daniel J. Rader, Clint L. Miller, Boxiang Liu, Victor G. Castano, Erik Ingelsson, Abhiram Rao, Milos Pjanic, Thomas Quertermous

مصطلحات موضوعية: 0301 basic medicine, Risk, Myocytes, Smooth Muscle, Quantitative Trait Loci, Genomics, Genome-wide association study, Coronary Artery Disease, Computational biology, PDGFRA, 030204 cardiovascular system & hematology, Biology, Genome, Polymorphism, Single Nucleotide, Article, Cell Line, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, Genetic Predisposition to Disease, Epigenetics, Genetics (clinical), 030304 developmental biology, Epigenomics, Genetic association, 0303 health sciences, Coronary Vessels, 3. Good health, 030104 developmental biology, Gene Expression Regulation, Expression quantitative trait loci, 030217 neurology & neurosurgery, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d772ed7e88dbb5b5db1e662be3ddb331Test
https://doi.org/10.1101/309559Test