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المؤلفون: Xiaoguang Liu, Kaluvu Balaraman, Ciarán C. Lynch, Michaeline Hebron, Priya Ketankumar Shah, Shicheng Hu, Max Stevenson, Christian Wolf, Charbel Moussa
المصدر: International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8131
مصطلحات موضوعية: Organic Chemistry, Mice, Transgenic, Parkinson Disease, General Medicine, Catalysis, Computer Science Applications, Inorganic Chemistry, Mice, Inbred C57BL, Substantia Nigra, Disease Models, Animal, Mice, alpha-Synuclein, alpha-synuclein, USP13, BK50118-C, dopamine, Animals, Humans, Ubiquitin-Specific Proteases, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357dd6c2fddc2e31360bb4eadc9b37cfTest
https://pubmed.ncbi.nlm.nih.gov/35897705Test -
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المؤلفون: Yasar Torres-Yaghi, Jaeil Ahn, Clementina Ullman, Charbel Moussa, Timothy L Chiu, Michaeline Hebron, Christian Wolf, Kaluvu Balaraman, Ethan Weatherdon, Alexander A Missner, Fernando Pagan, Alan J. Fowler, Val Duka, Habtom W. Ressom, Wangke Shi, Xiaoguang Liu, Jonathan D Greenzaid
المصدر: Hum Mol Genet
مصطلحات موضوعية: Lewy Body Disease, Inflammation, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Discoidin Domain Receptor 1, Alzheimer Disease, Genetics, medicine, Animals, Humans, Receptor, Molecular Biology, Genetics (clinical), 030304 developmental biology, 0303 health sciences, DDR1, Lewy body, Autophagy, Neurodegeneration, Neurodegenerative Diseases, Parkinson Disease, General Medicine, medicine.disease, Vesicular transport protein, Disease Models, Animal, MicroRNAs, Pyrimidines, alpha-Synuclein, Cancer research, General Article, Erratum, medicine.symptom, 030217 neurology & neurosurgery, Discoidin domain
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075d71d16ec599e5424b1c5668f64defTest
https://doi.org/10.1093/hmg/ddaa177Test -
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المؤلفون: Xiaoguang Liu, Jaeil Ahn, Sanjana Mulki, Dalila Ferrante, Abigail Lawler, Wangke Shi, Xiong Jiang, Muhammad Anjum, Michaeline Hebron, Giuseppe Esposito, J. Nathan Starr, Nadia Yusuf, Yasar Torres-Yaghi, Sara Matar, Raymond Scott Turner, Elizabeth E. Mundel, Frank Berkowitz, Fernando Pagan, Charbel Moussa
المصدر: Annals of Neurology
مصطلحات موضوعية: Male, 0301 basic medicine, Drug, medicine.medical_specialty, media_common.quotation_subject, tau Proteins, Placebo, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Double-Blind Method, Pharmacokinetics, Alzheimer Disease, Internal medicine, medicine, Humans, Adverse effect, Research Articles, Aged, media_common, Amyloid beta-Peptides, business.industry, Brain, Middle Aged, Protein-Tyrosine Kinases, medicine.disease, Peptide Fragments, Leukemia, Pyrimidines, Treatment Outcome, 030104 developmental biology, Neurology, Tolerability, Nilotinib, Positron-Emission Tomography, Female, Neurology (clinical), business, Biomarkers, 030217 neurology & neurosurgery, medicine.drug, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9740998e0f9ee27ce45bf125b868cbb4Test
http://europepmc.org/articles/PMC7383852Test -
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المؤلفون: Xiaokong Gao, Alexander A Missner, Bahjat T. Kurd-Misto, Charbel Moussa, Ruchong Wang, Alan J. Fowler, Xiaoguang Liu, Michaeline Hebron
المصدر: Drugs in R&D
Drugs in R&D, Vol 19, Iss 2, Pp 149-166 (2019)مصطلحات موضوعية: Male, Mice, Transgenic, Radotinib, 030226 pharmacology & pharmacy, Hippocampus, 03 medical and health sciences, Mice, 0302 clinical medicine, Alzheimer Disease, Mesencephalon, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Animals, Humans, Original Research Article, RNA, Small Interfering, Proto-Oncogene Proteins c-abl, Discoidin Domain Receptors, Protein Kinase Inhibitors, 030203 arthritis & rheumatology, Pharmacology, DDR1, ABL, Chemistry, lcsh:RM1-950, Neurodegeneration, Parkinson Disease, medicine.disease, Rats, Disease Models, Animal, lcsh:Therapeutics. Pharmacology, src-Family Kinases, Nilotinib, Blood-Brain Barrier, Gene Knockdown Techniques, Cancer research, Tyrosine kinase, Bosutinib, Proto-oncogene tyrosine-protein kinase Src, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6bd9ce70107aba3986d2ff080e1377Test
http://europepmc.org/articles/PMC6544596Test -
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المؤلفون: Michaeline Hebron, Xiaoguang Liu, Charbel Moussa, Irina Lonskaya, Wangke Shi
المصدر: Human Molecular Genetics. 28:548-560
مصطلحات موضوعية: 0301 basic medicine, Ubiquitin-Specific Proteases, Ubiquitin-Protein Ligases, Biology, Parkin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Ubiquitin, Endopeptidases, Genetics, Humans, RNA, Small Interfering, Molecular Biology, Genetics (clinical), Alpha-synuclein, Synucleinopathies, Gene knockdown, Ubiquitination, Brain, Parkinson Disease, General Medicine, Protein ubiquitination, nervous system diseases, Cell biology, Ubiquitin ligase, Pyrimidines, 030104 developmental biology, Gene Expression Regulation, chemistry, Gene Knockdown Techniques, alpha-Synuclein, biology.protein, Autopsy, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0530cd0c2db90f4de72db361378ababTest
https://doi.org/10.1093/hmg/ddy365Test -
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المؤلفون: Charbel Moussa, Michaeline Hebron, Monica Javidnia
المصدر: Journal of the Neurological Sciences. 391:90-99
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Glutamine, Proton Magnetic Resonance Spectroscopy, Glutamic Acid, Hippocampus, Glutamate-glutamine cycle, Mice, Transgenic, tau Proteins, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Nitriles, mental disorders, Autophagy, medicine, Animals, Humans, Enzyme Inhibitors, Neurotransmitter, Aniline Compounds, Glutamate receptor, Brain, Disease Models, Animal, Neuroprotective Agents, Pyrimidines, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Tauopathies, Neurology, chemistry, Astrocytes, Forebrain, Quinolines, Female, Neurology (clinical), Brainstem, 030217 neurology & neurosurgery, Astrocyte
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7fe9b5b735c60aa3596a8253a7fc67Test
https://doi.org/10.1016/j.jns.2018.06.005Test -
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المؤلفون: Dalila Ferrante, Charbel Moussa, Michaeline Hebron, Sanjana Mulki, Sara Matar, Fernando Pagan, Yasar Torres-Yaghi, Jaeil Ahn, Barbara Wilmarth
المصدر: Movement disorders : official journal of the Movement Disorder Society. 36(3)
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Levodopa, Movement disorders, Parkinson's disease, Subgroup analysis, Antiparkinson Agents, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Internal medicine, medicine, Humans, Adverse effect, business.industry, Montreal Cognitive Assessment, Parkinson Disease, medicine.disease, 030104 developmental biology, Pyrimidines, Neurology, Nilotinib, Tolerability, Quality of Life, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bae32caedf1859fe38ffe94417a273Test
https://pubmed.ncbi.nlm.nih.gov/34543463Test -
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المؤلفون: Bahjat T. Kurd-Misto, Wangke Shi, Chen Wang, Xiaoguang Liu, Dalila Ferrante, Michaeline Hebron, Sanjana Mulki, Elizabeth Lekah, Charbel Moussa
المصدر: Journal of Alzheimer's disease : JAD. 72(2)
مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Amyloid, Mice, Transgenic, Plaque, Amyloid, tau Proteins, 03 medical and health sciences, Amyloid beta-Protein Precursor, Mice, 0302 clinical medicine, Ubiquitin, Alzheimer Disease, mental disorders, Endopeptidases, medicine, Amyloid precursor protein, Animals, Humans, RNA, Small Interfering, Brain Chemistry, Cerebral Cortex, Neurons, Gene knockdown, biology, General Neuroscience, Autophagy, Neurodegeneration, General Medicine, medicine.disease, Protein ubiquitination, Cell biology, Mice, Inbred C57BL, Psychiatry and Mental health, Clinical Psychology, 030104 developmental biology, Proteasome, Gene Knockdown Techniques, biology.protein, Ubiquitin-Specific Proteases, Geriatrics and Gerontology, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da719320afac849aa99bc9e9626b7a3Test
https://pubmed.ncbi.nlm.nih.gov/31594232Test -
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المؤلفون: Charbel Moussa, Margo Peyton, Irina Lonskaya, Ruochong Wang, Xiaokong Gao, Xiaoguang Liu, Michaeline Hebron
المصدر: Journal of Neuroimmunology. 311:1-9
مصطلحات موضوعية: Male, 0301 basic medicine, Immunology, Mice, Transgenic, Biology, Hippocampus, Amyloid beta-Protein Precursor, Mice, Neuroblastoma, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Cell Line, Tumor, medicine, Animals, Humans, Immunology and Allergy, Receptor, Discoidin Domain Receptors, DDR1, Gene knockdown, Amyloid beta-Peptides, Microglia, TREM2, Neurodegeneration, Parkinson Disease, medicine.disease, Peptide Fragments, Rats, Up-Regulation, 030104 developmental biology, medicine.anatomical_structure, Neurology, Case-Control Studies, Mutation, alpha-Synuclein, Cancer research, Cytokines, Encephalitis, Female, Neurology (clinical), Tyrosine kinase, 030217 neurology & neurosurgery, Discoidin domain
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68048c95643138b71deaf609ba6bfe5eTest
https://doi.org/10.1016/j.jneuroim.2017.07.009Test -
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المؤلفون: Margo Peyton, Jaeil Ahn, Xiaoguang Liu, Alan J. Fowler, Michaeline Hebron, Sara Matar, Joy Arellano, Nadia Yusuf, Barbara Wilmarth, Charbel Moussa, Sorell L. Schwartz, Nathan J. Starr, Helen H. Howard, Fernando Pagan, Yasar Torres-Yaghi, Elizabeth E. Mundel, Abigail Lawler
المصدر: Pharmacology Research & Perspectives
مصطلحات موضوعية: Parkinson's disease, Dopamine, Pharmacology, 030226 pharmacology & pharmacy, Tyrosine-kinase inhibitor, Cohort Studies, Placebos, chemistry.chemical_compound, 0302 clinical medicine, TREM2, Parkinson, General Pharmacology, Toxicology and Pharmaceutics, Receptors, Immunologic, Aged, 80 and over, education.field_of_study, Membrane Glycoproteins, Homovanillic acid, Brain, Parkinson Disease, Middle Aged, Protein-Tyrosine Kinases, alpha‐synuclein, Neurology, 030220 oncology & carcinogenesis, alpha-Synuclein, Original Article, medicine.drug, Adult, medicine.drug_class, Population, 03 medical and health sciences, Pharmacokinetics, Double-Blind Method, medicine, Humans, education, Protein Kinase Inhibitors, Aged, Dose-Response Relationship, Drug, business.industry, Homovanillic Acid, Drugs, Investigational, Original Articles, medicine.disease, Nilotinib, Pyrimidines, chemistry, Pharmacodynamics, 3,4-Dihydroxyphenylacetic Acid, business, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71eff89df2d80ff2d3ac18c9fbf3a382Test
https://pubmed.ncbi.nlm.nih.gov/30906562Test