المؤلفون: Alves, Raquel, Pires, Ana, Jorge, Joana, Balça-Silva, Joana, Gonçalves, Ana Cristina, Sarmento-Ribeiro, Ana Bela

مصطلحات موضوعية: acute leukemia, apoptosis, batimastat (BB-94), matrix metalloproteinase, multiple myeloma, myelodysplasia, Humans, Cell Line, Tumor, Cell Survival, Antineoplastic Agents, Cytostatic Agents, Cell Proliferation, Hydroxamic Acids, HL-60 Cells, Matrix Metalloproteinase Inhibitors, Cell Cycle Checkpoints, MAP Kinase Signaling System, Leukemia, Myeloid, Acute, Phenylalanine, Hematologic Neoplasms, Thiophenes

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB/04539/2020/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP/04539/2020/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/LA/P/0058/2020/PT; https://www.mdpi.com/1422-0067/25/8/4554Test; https://hdl.handle.net/10316/115122Test

الإتاحة: https://doi.org/10.3390/ijms25084554Test
https://hdl.handle.net/10316/115122Test

المؤلفون: Owyong, Mark, Chou, Jonathan, van den Bijgaart, Renske JE, Kong, Niwen, Efe, Gizem, Maynard, Carrie, Talmi-Frank, Dalit, Solomonov, Inna, Koopman, Charlotte, Hadler-Olsen, Elin, Headley, Mark, Lin, Charlene, Wang, Chih-Yang, Sagi, Irit, Werb, Zena, Plaks, Vicki

المصدر: Life Science Alliance. 2(6)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Biotechnology, Lung, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research, Cancer, Breast Cancer, Prevention, Animals, Antibodies, Breast Neoplasms, CD8-Positive T-Lymphocytes, Carcinogenesis, Cell Line, Tumor, Female, HEK293 Cells, Humans, Lung Neoplasms, Mammary Neoplasms, Experimental, Matrix Metalloproteinase 9, Matrix Metalloproteinase Inhibitors, Mice, Mice, Inbred Strains, Neoplasm Invasiveness, Neoplasm Metastasis, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3339f30kTest

المؤلفون: Raeeszadeh-Sarmazdeh, Maryam, Greene, Kerrie A, Sankaran, Banumathi, Downey, Gregory P, Radisky, Derek C, Radisky, Evette S

المصدر: Journal of Biological Chemistry. 294(24)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 2.1 Biological and endogenous factors, Aetiology, Amino Acid Sequence, Binding Sites, Catalytic Domain, Crystallography, X-Ray, Directed Molecular Evolution, Humans, Matrix Metalloproteinase 3, Matrix Metalloproteinase Inhibitors, Mutation, Protein Binding, Protein Conformation, Protein Domains, Tissue Inhibitor of Metalloproteinase-1, Two-Hybrid System Techniques, crystal structure, directed evolution, matrix metalloproteinase, metalloprotease, protease inhibitor, protein domain, protein engineering, protein structure, protein-protein interaction, tissue inhibitor of metalloproteinase, yeast surface display, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0vs384t9Test

المؤلفون: Ateia, Islam M, Sutthiboonyapan, Pimchanok, Kamarajan, Pachiyappan, Jin, Taocong, Godovikova, Valentina, Kapila, Yvonne L, Fenno, J Christopher

المصدر: Cellular Microbiology. 20(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Dental/Oral and Craniofacial Disease, Genetics, Biotechnology, Cells, Cultured, Epigenesis, Genetic, Histone Code, Humans, Matrix Metalloproteinase 2, Matrix Metalloproteinase Inhibitors, Periodontal Ligament, Treponema denticola, Microbiology, Medical Microbiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/55m202qvTest

المؤلفون: Klymenko, Y, Kim, O, Loughran, E, Yang, J, Lombard, R, Alber, M, Stack, MS

المصدر: Oncogene. 36(42)

مصطلحات موضوعية: Ovarian Cancer, Rare Diseases, Cancer, Aetiology, 2.1 Biological and endogenous factors, Animals, Cadherins, Carcinoma, Ovarian Epithelial, Cell Adhesion, Cell Aggregation, Cell Line, Tumor, Dipeptides, Disease Models, Animal, Female, Gene Expression Regulation, Neoplastic, Humans, Matrix Metalloproteinase 14, Matrix Metalloproteinase Inhibitors, Mesoderm, Mice, Mice, Inbred C57BL, Neoplasm Invasiveness, Neoplasms, Glandular and Epithelial, Organ Culture Techniques, Ovarian Neoplasms, Peritoneal Neoplasms, Clinical Sciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1515d5mvTest

المؤلفون: Remacle, Albert G, Cieplak, Piotr, Nam, Dong Hyun, Shiryaev, Sergey A, Ge, Xin, Strongin, Alex Y

المصدر: Oncotarget. 5

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Animals, Antibodies, Blocking, Antineoplastic Agents, Immunological, Binding, Competitive, Catalytic Domain, Cell Line, Tumor, Cell Movement, Cell Survival, Collagen, Disease Models, Animal, Enzyme Activation, Female, Heterografts, Humans, Immunoglobulin Fab Fragments, Matrix Metalloproteinase 14, Matrix Metalloproteinase Inhibitors, Mice, Models, Molecular, Molecular Conformation, Neoplasm Metastasis, Neoplasm Staging, Neoplasms, Protein Binding, Proteolysis, Recombinant Proteins, metastasis, cancer, MT1-MMP, antibody, proteinase, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/70t398kcTest

المؤلفون: Nam, Dong Hyun, Rodriguez, Carlos, Remacle, Albert G, Strongin, Alex Y, Ge, Xin

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(52)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Prevention, Cancer, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Amino Acid Motifs, Animals, Antibodies, Binding Sites, Antibody, Camelus, Catalytic Domain, Complementarity Determining Regions, Escherichia coli, Humans, Immunoglobulin Fab Fragments, Inhibitory Concentration 50, Matrix Metalloproteinase 14, Matrix Metalloproteinase Inhibitors, Mice, Molecular Conformation, Peptide Library, Surface Plasmon Resonance, inhibitory antibody, long CDR, synthetic library, convex paratope, MMP

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1mr7d9svTest

المؤلفون: Abd-Elaziz, Khalid, Voors-Pette, Christine, Wang, Kang Ling, Pan, Sandy, Lee, Yisheng, Mao, John, Li, Yuhua, Chien, Benjamin, Lau, David, Diamant, Zuzana

المصدر: Abd-Elaziz , K , Voors-Pette , C , Wang , K L , Pan , S , Lee , Y , Mao , J , Li , Y , Chien , B , Lau , D & Diamant , Z 2021 , ' First-in-Man Safety, Tolerability, and Pharmacokinetics of a Novel and Highly Selective Inhibitor of Matrix Metalloproteinase-12, FP-025 : Results from Two Randomized Studies in Healthy Subjects ' , Clinical Drug investigation , vol. 41 , pp. 65-76 . https://doi.org/10.1007/s40261-020-00981-9Test

مصطلحات موضوعية: Adult, Area Under Curve, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Male, Matrix Metalloproteinase 12/drug effects, Matrix Metalloproteinase Inhibitors/administration & dosage, Young Adult

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/cd450430-dfe3-4226-bdea-e797b8b23e84Test

الإتاحة: https://doi.org/10.1007/s40261-020-00981-9Test
https://hdl.handle.net/11370/cd450430-dfe3-4226-bdea-e797b8b23e84Test
https://research.rug.nl/en/publications/cd450430-dfe3-4226-bdea-e797b8b23e84Test
https://pure.rug.nl/ws/files/632784246/s40261_020_00981_9.pdfTest
http://www.scopus.com/inward/record.url?scp=85097679660&partnerID=8YFLogxKTest

المؤلفون: Abd-Elaziz, Khalid, Jesenak, Milos, Vasakova, Martina, Diamant, Zuzana

المصدر: Abd-Elaziz , K , Jesenak , M , Vasakova , M & Diamant , Z 2021 , ' Revisiting matrix metalloproteinase 12 : its role in pathophysiology of asthma and related pulmonary diseases ' , Current Opinion in Pulmonary Medicine , vol. 27 , no. 1 , pp. 54-60 . https://doi.org/10.1097/MCP.0000000000000743Test

مصطلحات موضوعية: Animals, Asthma/drug therapy, Biomarkers/metabolism, COVID-19/enzymology, Humans, Idiopathic Pulmonary Fibrosis/drug therapy, Matrix Metalloproteinase 12/metabolism, Matrix Metalloproteinase Inhibitors/therapeutic use, Pulmonary Disease, Chronic Obstructive/drug therapy, COVID-19 Drug Treatment

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/239194cb-0935-4860-a9b5-cfe7b24c9a4aTest

الإتاحة: https://doi.org/10.1097/MCP.0000000000000743Test
https://hdl.handle.net/11370/239194cb-0935-4860-a9b5-cfe7b24c9a4aTest
https://research.rug.nl/en/publications/239194cb-0935-4860-a9b5-cfe7b24c9a4aTest
https://pure.rug.nl/ws/files/192308869/Revisiting_matrix_metalloproteinase_12_its_role.10.pdfTest

المؤلفون: Zhibiao, Qing, Wuxiong, Yuan, Jiansong, Wang, Wei, Song, Jianjun, Luo, Xuecheng, Wu, Qiang, Lu, Yuanwei, Li, Mingqiang, Zeng

المصدر: International Urology and Nephrology. 54:2855-2866

مصطلحات موضوعية: STAT3 Transcription Factor, Tissue Inhibitor of Metalloproteinase-1, Proto-Oncogene Proteins c-jun, Urology, Constriction, Pathologic, Fibroblasts, Matrix Metalloproteinase Inhibitors, Calcium Channel Blockers, Collagen Type I, Transforming Growth Factor beta1, Collagen Type III, Verapamil, Nephrology, Transforming Growth Factors, Humans, RNA, Collagen, RNA, Messenger, Smad3 Protein, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Luciferases, Signal Transduction, Ureteral Obstruction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73fa7f49e73eba8ecb7a27b7783d77f1Test
https://doi.org/10.1007/s11255-022-03284-4Test