المؤلفون: Dixon-Zegeye, Miriam, Shaw, Rachel, Collins, Linda, Perez-Smith, Kendra, Ooms, Alexander, Qiao, Maggie, Pantziarka, Pan, Izatt, Louise, Tischkowitz, Marc, Harrison, Rachel E, George, Angela, Woodward, Emma R, Lord, Simon, Hawkes, Lara, Evans, D Gareth, Franklin, James, Hanson, Helen, Blagden, Sarah P

مصطلحات موضوعية: Cancer, Chemoprevention, LFS, Li-Fraumeni syndrome, Metformin, Precision-Prevention, TP53, p53, Adult, Humans, Mice, Animals, Quality of Life, Germ-Line Mutation, Magnetic Resonance Imaging, Genetic Predisposition to Disease, Randomized Controlled Trials as Topic, Clinical Trials, Phase II as Topic

وصف الملف: application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/366650Test

الإتاحة: https://www.repository.cam.ac.uk/handle/1810/366650Test

المؤلفون: Muskens, Ivo S, de Smith, Adam J, Zhang, Chenan, Hansen, Helen M, Morimoto, Libby, Metayer, Catherine, Ma, Xiaomei, Walsh, Kyle M, Wiemels, Joseph L

المصدر: Neuro-Oncology. 22(6)

مصطلحات موضوعية: Rare Diseases, Brain Disorders, Genetic Testing, Pediatric Cancer, Neurosciences, Prevention, Brain Cancer, Cancer, Biotechnology, Human Genome, Genetics, Clinical Research, Pediatric, 2.1 Biological and endogenous factors, Aetiology, California, Child, Genetic Predisposition to Disease, Germ-Line Mutation, Glioma, Humans, pediatric glioma, Li-Fraumeni syndrome, glioblastoma, germline variant, exome sequencing, Li–Fraumeni syndrome, Oncology and Carcinogenesis, Oncology & Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/40b525bbTest

المؤلفون: Fortuno, Cristina, Lee, Kristy, Olivier, Magali, Pesaran, Tina, Mai, Phuong L, Andrade, Kelvin C, Attardi, Laura D, Crowley, Stephanie, Evans, D Gareth, Feng, Bing‐Jian, Foreman, Ann KM, Frone, Megan N, Huether, Robert, James, Paul A, McGoldrick, Kelly, Mester, Jessica, Seifert, Bryce A, Slavin, Thomas P, Witkowski, Leora, Zhang, Liying, Plon, Sharon E, Spurdle, Amanda B, Savage, Sharon A, Panel, the ClinGen TP53 Variant Curation Expert

المصدر: Human Mutation. 42(3)

مصطلحات موضوعية: Human Genome, Prevention, Genetics, Cancer, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Genetic Testing, Genetic Variation, Germ Cells, Humans, Li-Fraumeni Syndrome, Tumor Suppressor Protein p53, United States, cancer, pathogenic variant, TP53, variant curation, ClinGen TP53 Variant Curation Expert Panel, Clinical Sciences, Genetics & Heredity

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6r4715qgTest

المؤلفون: Sloan, Emily A, Hilz, Stephanie, Gupta, Rohit, Cadwell, Cathryn, Ramani, Biswarathan, Hofmann, Jeffrey, Kline, Cassie N, Banerjee, Anu, Reddy, Alyssa, Oberheim Bush, Nancy Ann, Chang, Susan, Braunstein, Steve, Chang, Edward F, Raffel, Corey, Gupta, Nalin, Sun, Peter P, Kim, John YH, Moes, Gregory, Alva, Elizabeth, Li, Rong, Bruggers, Carol S, Alashari, Mouied, Wetmore, Cynthia, Garg, Shipra, Dishop, Megan, Van Ziffle, Jessica, Onodera, Courtney, Devine, Patrick, Grenert, James P, Lee, Julieann C, Phillips, Joanna J, Pekmezci, Melike, Tihan, Tarik, Bollen, Andrew W, Berger, Mitchel S, Costello, Joseph F, Perry, Arie, Solomon, David A

المصدر: Acta Neuropathologica. 139(5)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Adolescent, Adult, Child, Child, Preschool, Female, Genetic Predisposition to Disease, Germ-Line Mutation, Glioma, Humans, Li-Fraumeni Syndrome, Male, Tumor Suppressor Protein p53, Young Adult, Clinical Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6d89g89fTest

المؤلفون: Light, Nicholas, Layeghifard, Mehdi, Attery, Ayush, Subasri, Vallijah, Zatzman, Matthew, Anderson, Nathaniel D, Hatkar, Rupal, Blay, Sasha, Chen, David, Novokmet, Ana, Fuligni, Fabio, Tran, James, de Borja, Richard, Agarwal, Himanshi, Waldman, Larissa, Abegglen, Lisa M, Albertson, Daniel, Finlay, Jonathan L, Hansford, Jordan R, Behjati, Sam, Villani, Anita, Gerstung, Moritz, Alexandrov, Ludmil B, Somers, Gino R, Schiffman, Joshua D, Rotter, Varda, Malkin, David, Shlien, Adam

المصدر: nlmid: 101528555 ; essn: 2041-1723

مصطلحات موضوعية: Humans, Tumor Suppressor Protein p53, Genetic Predisposition to Disease, DNA Copy Number Variations, Phosphatidylinositol 3-Kinases, Phylogeny, Li-Fraumeni Syndrome, Germ-Line Mutation, Mutation, Neoplastic Syndromes, Hereditary

وصف الملف: application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/346286Test

الإتاحة: https://doi.org/10.17863/CAM.93707Test
https://www.repository.cam.ac.uk/handle/1810/346286Test

المؤلفون: Dixon-Zegeye, M., Shaw, R., Collins, L., Perez-Smith, K., Ooms, A., Qiao, M., Pantziarka, P., Izatt, L., Tischkowitz, M., Harrison, R. E., George, A., Woodward, E. R., Lord, S., Hawkes, L., Evans, D. G., Franklin, J., Hanson, H., Blagden, S. P.

مصطلحات موضوعية: Adult, Humans, Mice, Animals, Li-Fraumeni Syndrome/diagnostic imaging/genetics/prevention & control, Metformin/adverse effects, Quality of Life, Germ-Line Mutation, Magnetic Resonance Imaging, Genetic Predisposition to Disease, Randomized Controlled Trials as Topic, Clinical Trials, Phase II as Topic, Cancer, Chemoprevention, Lfs, Li-Fraumeni syndrome, Metformin, Precision-Prevention

العلاقة: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/38308321Test/; Dixon-Zegeye M, Shaw R, Collins L, Perez-Smith K, Ooms A, Qiao M, et al. Cancer Precision-Prevention trial of Metformin in adults with Li Fraumeni syndrome (MILI) undergoing yearly MRI surveillance: a randomised controlled trial protocol. Trials. 2024;25(1):103.; Trials; PMC10837926; https://hdl.handle.net/11287/623225Test

الإتاحة: https://doi.org/10.1186/s13063-024-07929-wTest
https://hdl.handle.net/11287/623225Test

المؤلفون: Martínez, Paula, Sánchez-Vázquez, Raúl, Ferrara-Romeo, Iole, Serrano, Rosa, Flores, Juana M, Blasco, MA

المساهمون: Agencia Estatal de Investigación (España), Comunidad de Madrid (España), Ministerio de Ciencia e Innovación (España), Unión Europea. Comisión Europea. European Research Council (ERC), Fundación Banco Santander

مصطلحات موضوعية: Hemangiosarcoma, Telomerase, Animals, Endothelial Cells, Fibroblasts, Humans, Li-Fraumeni Syndrome, Mice, Mutation, Shelterin Complex, Telomere, Telomere-Binding Proteins

العلاقة: https://doi.org/10.1371/journal.pgen.1010260Test.; info:eu-repo/grantAgreement/EC/H2020/882385/EU; info:eu-repo/grantAgreement/ES/SAF2017-82623-R; info:eu-repo/grantAgreement/ES/SAF201572455-EXP; PLoS Genet . 2022 ;18(6):e1010260; http://hdl.handle.net/20.500.12105/18980Test; PLoS genetics

الإتاحة: https://doi.org/20.500.12105/18980Test
https://doi.org/10.1371/journal.pgen.1010260Test
https://hdl.handle.net/20.500.12105/18980Test

المؤلفون: Castiaux, Julie, Vandernoot, Isabelle, Dallemagne, Julie, Bruneau, Marie, Delaunoy, Melanie, Peyrassol, Xavier, Heimann, Pierre, De Wilde, Virginie, Wolfromm, Alice

المصدر: Clinical lymphoma, myeloma & leukemia, 21 (8

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Adult, Antineoplastic Combined Chemotherapy Protocols -- therapeutic use, Female, Germ-Line Mutation, Humans, Li-Fraumeni Syndrome -- drug therapy -- genetics, Multiple Myeloma -- drug therapy -- genetics, Thyroid Neoplasms -- drug therapy -- genetics, Treatment Outcome, Tumor Suppressor Protein p53 -- genetics, Li-Fraumeni syndrome, Multiple myeloma, Mutational load, Prognosis, Thyroid carcinoma, Treatment

وصف الملف: 2 full-text file(s): application/pdf | application/pdf

العلاقة: uri/info:doi/10.1016/j.clml.2020.10.001; uri/info:pii/S2152-2650(20)30552-8; uri/info:pmid/34049842; uri/info:scp/85106661434; https://dipot.ulb.ac.be/dspace/bitstream/2013/355097/5/1-s2.0-S2152265020305528-main.pdfTest; https://dipot.ulb.ac.be/dspace/bitstream/2013/355097/1/elsevier_338741.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/355097Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/355097Test
https://dipot.ulb.ac.be/dspace/bitstream/2013/355097/5/1-s2.0-S2152265020305528-main.pdfTest
https://dipot.ulb.ac.be/dspace/bitstream/2013/355097/1/elsevier_338741.pdfTest

المؤلفون: Juliane Nees, Senta Kiermeier, Farina Struewe, Myriam Keymling, Imad Maatouk, Christian P. Kratz, Sarah Schott

المصدر: Current Oncology; Volume 29; Issue 10; Pages: 7768-7778

مصطلحات موضوعية: Adult, Male, Li-Fraumeni Syndrome, Health Behavior, Quality of Life, pathogenic TP53 germline variant, Li-Fraumeni syndrome, cancer prevention, physical activity, cancer predisposition, SF-12, MEDAS, Humans, Female, Genetic Predisposition to Disease, Tumor Suppressor Protein p53, Germ-Line Mutation

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb7375324e9cedc51f8f81fd360fde9Test
https://doi.org/10.3390/curroncol29100614Test

المؤلفون: Kratz, CP, Freycon, C, Maxwell, KN, Nichols, KE, Schiffman, JD, Evans, DG, Achatz, MI, Savage, SA, Weitzel, JN, Garber, JE, Hainaut, P, Malkin, D

المصدر: Kratz , CP , Freycon , C , Maxwell , KN , Nichols , KE , Schiffman , JD , Evans , DG , Achatz , MI , Savage , SA , Weitzel , JN , Garber , JE , Hainaut , P & Malkin , D 2021 , ' Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis. ' , JAMA oncology , vol. 7 , no. 12 , pp. 1800-1805 . https://doi.org/10.1001/jamaoncol.2021.4398Test

مصطلحات موضوعية: Cohort Studies, Genetic Predisposition to Disease, Germ Cells, Germ-Line Mutation, Humans, International Agencies, Li-Fraumeni Syndrome/epidemiology, Tumor Suppressor Protein p53/genetics

الإتاحة: https://doi.org/10.1001/jamaoncol.2021.4398Test
https://research.manchester.ac.uk/en/publications/2c2ee5b0-1578-4e8d-8bd6-00b9d16217e2Test