نتائج البحث - "Joerg Reinders"

1

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

المصدر: Journal of Hepatology
Journal of hepatology, 77(1):71-83
JOURNAL OF HEPATOLOGY

مصطلحات موضوعية: Bile Acids and Salts, Mice, Inbred C57BL, Mice, Liver, Hepatology, Hepatocytes, Animals, Humans, APAP, tight junctions, intravital imaging, acute liver failure, blood-bile barrier, Chemical and Drug Induced Liver Injury, Drug Overdose, Acetaminophen, Acetylcysteine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e451d5db326137d2572330d5e61c583cTest

2

Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice

المؤلفون: Andreas Steudter, Joerg Heeren, Ahmed Ghallab, Joerg Reinders, Johannes Herkel, Björn Wieschendorf, Antonella Carambia, Christoph Schramm, Dorothee Schwinge, Sebastian Zuehlke, Ansgar W. Lohse, Christoph Lommetz, Fenja Amrei Schuran

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, 11(2):371-388

مصطلحات موضوعية: 0301 basic medicine, Male, Indoles, Ahr, AST, aspartate aminotransferase, Pharmacology, Mice, 0302 clinical medicine, APAP, Acute Liver Failure, Cyp1a2, Basic Helix-Loop-Helix Transcription Factors, GSH, glutathione, TUNEL, terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling, Original Research, Liver injury, Mice, Knockout, biology, Chemistry, digestive, oral, and skin physiology, Gastroenterology, respiratory system, HSC, hepatic stellate cell, medicine.anatomical_structure, Liver, Ahr, aryl hydrocarbon receptor, Hepatocyte, Knockout mouse, 030211 gastroenterology & hepatology, Female, Chemical and Drug Induced Liver Injury, medicine.drug, APAP, acetaminophen, 03 medical and health sciences, ALT, alanine aminotransferase, medicine, Animals, Humans, Transcription factor, Aryl hydrocarbon receptor activity, Acetaminophen, Hepatology, CYP1A2, Liver Failure, Acute, Aryl hydrocarbon receptor, medicine.disease, Disease Models, Animal, Thiazoles, 030104 developmental biology, Receptors, Aryl Hydrocarbon, biology.protein, Hepatocytes, H&E, hematoxylin and eosin, NPC, nonparenchymal cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b042fbf1a6202ae6e40d984dc3eeab5Test
https://pubmed.ncbi.nlm.nih.gov/32932016Test

3

Glycine amidinotransferase (GATM), renal Fanconi syndrome, and kidney failure

المؤلفون: Mahim Jain, Daniela Iancu, Joana Raquel Martins, Robert J. Unwin, Kathrin Renner, Naomi Issler, Chi-Un Choe, Hannes Doellerer, Ralph Witzgall, Stephen B. Walsh, Sulochana Devi, Monika Mozere, Robert Kleta, Johann M.B Simbuerger, Kevin O'Brien, Anne Kesselheim, Markus Reichold, Paldeep S. Atwal, Michael Kasgharian, Uta Lichter-Konecki, William A. Gahl, Carlos Ferreira, Julia Wiesner, Vaksha Patel, Horia Stanescu, Peter J. Oefner, Graciana Jaureguiberry, Christopher W. Pugh, Mario Milani, Joerg Reinders, Christina Sterner, Detlef Bockenhauer, Sue Povey, Simona Dumitriu, Chris Laing, Ben Davies, Carsten Broeker, David S. Konecki, Roland Schmitt, Alexander Hammers, Richard Sandford, Enriko Klootwijk, Dirk Isbrandt, Richard Warth, Daniel P. Gale, Andrew M. Hall, Alberto Cebrian-Serrano, Alexander J. Howie, Weibin Zhou, Geoffrey Charles-Edwards, Ines Tegtmeier, Edgar A. Otto, Mehmet Tekman, Katja Dettmer

المصدر: Journal of the American Society of Nephrology 29(7), 1849-1858 (2018). doi:10.1681/ASN.2017111179
Journal of the American Society of Nephrology 29 (2018): 1849–1858. doi:10.1681/ASN.2017111179
info:cnr-pdr/source/autori:Reichold M, Klootwijk ED, Reinders J, Otto EA, Milani M, Broeker C, Laing C, Wiesner J, Devi S, Zhou W, Schmitt R, Tegtmeier I, Sterner C, Doellerer H, Renner K, Oefner PJ, Dettmer K, Simbuerger JM, Witzgall R, Stanescu HC, Dumitriu S, Iancu D, Patel V, Mozere M, Tekman M, Jaureguiberry G, Issler N, Kesselheim A, Walsh SB, Gale DP, Howie AJ, Martins JR, Hall AM, Kasgharian M, O'Brien K, Ferreira CR, Atwal PS, Jain M, Hammers A, Charles-Edwards G, Choe CU, Isbrandt D, Cebrian-Serrano A, Davies B, Sandford RN, Pugh C, Konecki DS, Povey S, Bockenhauer D, Lichter-Konecki U, Gahl WA, Unwin RJ, Warth R, Kleta R/titolo:Glycine Amidinotransferase (GATM), Renal Fanconi Syndrome, and Kidney Failure/doi:10.1681%2FASN.2017111179/rivista:Journal of the American Society of Nephrology/anno:2018/pagina_da:1849/pagina_a:1858/intervallo_pagine:1849–1858/volume:29

مصطلحات موضوعية: complications [Fanconi Syndrome], Male, 0301 basic medicine, Nephrology, metabolism [Amidinotransferases], Amidinotransferases, metabolism [Kidney Failure, Chronic], Inflammasomes, Molecular Conformation, 030232 urology & nephrology, Mitochondrion, pathology [Mitochondria], Mice, chemistry.chemical_compound, pathology [Fanconi Syndrome], 0302 clinical medicine, Missense mutation, metabolism [Reactive Oxygen Species], Mice, Knockout, Kidney, metabolism [Fanconi Syndrome], Genetic disorder, General Medicine, etiology [Kidney Failure, Chronic], Mitochondria, Pedigree, Editorial, medicine.anatomical_structure, Knockout mouse, genetics [Amidinotransferases], Female, Heterozygote, medicine.medical_specialty, Mutation, Missense, Biology, Creatine, genetics [Kidney Failure, Chronic], Young Adult, 03 medical and health sciences, genetic diseases, Tubulopathy, Internal medicine, genetics [Fanconi Syndrome], glycine amidinotransferase, medicine, Animals, Humans, Computer Simulation, ddc:610, Aged, Infant, Sequence Analysis, DNA, Fanconi Syndrome, metabolism [Mitochondria], medicine.disease, 030104 developmental biology, chemistry, Mutation, Cancer research, Kidney Failure, Chronic, pathology [Kidney Failure, Chronic], Reactive Oxygen Species, metabolism [Inflammasomes]