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المؤلفون: David G. Schatz, Jean-Marie Buerstedde, Suhas S.P. Rao, Jukka Alinikula, Filip Šenigl, Yaakov Maman, Ravi K. Dinesh, Lubomira Pecnova, David Weisz, Jiri Hejnar, Rafael Casellas, Rashu B. Seth, Arina D. Omer, Erez Lieberman Aiden
المصدر: Cell reports
Cell Reports, Vol 29, Iss 12, Pp 3902-3915.e8 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Somatic hypermutation, RNA polymerase II, Computational biology, Genome, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), Cell Line, Tumor, Cytidine Deaminase, Activation-induced (cytidine) deaminase, Humans, Enhancer, lcsh:QH301-705.5, Gene, Transcription factor, 030304 developmental biology, 0303 health sciences, biology, Lentivirus, Chromatin, 030104 developmental biology, Enhancer Elements, Genetic, HEK293 Cells, lcsh:Biology (General), Mutation, biology.protein, RNA Polymerase II, Somatic Hypermutation, Immunoglobulin, 030217 neurology & neurosurgery, Plasmids
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a368ddd3906f056ea5c400d34747c64Test
https://doi.org/10.2139/ssrn.3383796Test -
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المؤلفون: Shikha Sharma, Julian E. Sale, Teonchit Nuamchit, Hiroshi Arakawa, Jean-Marie Buerstedde, Kathryn H. Steele, Nicholas P.J. Brindle
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Directed Evolution, Somatic hypermutation, Ligand Binding Protein, Plasma protein binding, Protein Engineering, Biochemistry, Receptor tyrosine kinase, Angiopoietin-2, 03 medical and health sciences, 0302 clinical medicine, Cell surface receptor, Humans, Molecular Biology, 030304 developmental biology, 0303 health sciences, Endothelial Cell, biology, HEK 293 cells, Cell Surface Receptor, Cell Biology, Angiopoietin receptor, Molecular biology, Receptor, TIE-2, Ligand-binding Protein, Cell biology, Protein Structure, Tertiary, HEK293 Cells, Ectodomain, 030220 oncology & carcinogenesis, Protein Structure and Folding, biology.protein, Angiogenesis, Directed Molecular Evolution, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1831936e20d8708d4a4802c0db100abTest
http://europepmc.org/articles/PMC3829167Test -
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المؤلفون: Thomas Helleday, Hiroshi Arakawa, Yoshihito Taniguchi, Weihua Zeng, Jean-Marie Buerstedde, Hirobumi Teraoka, Julian E. Sale, Akira Yasui, Yasuhiro Murakawa, Shunichi Takeda, Kyoko Yokomori, Alihossein Saberi, Dávid Szüts, Li Lan, Helfrid Hochegger
المصدر: Mol. Cell. Biol. 27, 2562-2571 (2007)
مصطلحات موضوعية: DNA Repair, Ubiquitin-Protein Ligases, Poly ADP ribose polymerase, Saccharomyces cerevisiae, Topoisomerase-I Inhibitor, Cell Line, PARP1, Postreplication repair, Animals, Humans, DNA Breaks, Double-Stranded, Ku Autoantigen, Molecular Biology, Polymerase, Recombination, Genetic, biology, fungi, Antigens, Nuclear, Articles, Cell Biology, biology.organism_classification, Molecular biology, DNA-Binding Proteins, Non-homologous end joining, enzymes and coenzymes (carbohydrates), biology.protein, Camptothecin, Poly(ADP-ribose) Polymerases, Topoisomerase I Inhibitors, Homologous recombination, Chickens
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775e4473882301a6ccf0b683651a872aTest
https://doi.org/10.1128/mcb.01243-06Test -
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المؤلفون: J. Bachl, Jean-Marie Buerstedde, Randolph B. Caldwell
المصدر: Cytogenet. Genome Res. 117, 189-194 (2007)
مصطلحات موضوعية: B-Lymphocytes, Focus (computing), business.industry, Gene Expression, Biology, Cell Line, Protein evolution, Biotechnology, Green fluorescent protein, Directed enzyme evolution, In-vitro recombination, Somatic hypermutation, Gene conversion, Phage display, Region hypermutation, Antibody diversity, Escherichia-coli, Lympocyte line, B cell line, Genes, Reporter, Mutation, Genetics, Animals, Humans, business, Chickens, Molecular Biology, Genetics (clinical), Pharmaceutical industry
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8c0db9cc2e133ab83b2b3ef573c606Test
https://doi.org/10.1159/000103179Test -
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المؤلفون: Keiko Namikoshi, Mitsuyoshi Yamazoe, Kazuhiko Yamamoto, Kazunaga Agematsu, Jean-Marie Buerstedde, Shunichi Takeda, Hiroshi Arakawa, Masamichi Ishiai, Masayo Kimura, Nobuko Matsushita, Minoru Takata
المصدر: Molecular and Cellular Biology. 24:10733-10741
مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, DNA Repair, DNA repair, DNA damage, DNA Mutational Analysis, Molecular Sequence Data, RAD51, Biology, Cell Line, Fungal Proteins, XRCC2, Cell Line, Tumor, Two-Hybrid System Techniques, Animals, Humans, Point Mutation, Amino Acid Sequence, Organic Chemicals, DNA, Fungal, Molecular Biology, Fluorescent Dyes, Cell Nucleus, Recombination, Genetic, Endodeoxyribonucleases, X-Rays, Nuclear Proteins, Cell Biology, DNA Dynamics and Chromosome Structure, Protein Inhibitors of Activated STAT, Molecular biology, Protein Structure, Tertiary, DNA-Binding Proteins, Non-homologous end joining, Cross-Linking Reagents, DNA Repair Enzymes, Exodeoxyribonucleases, Microscopy, Fluorescence, Small Ubiquitin-Related Modifier Proteins, Cisplatin, ERCC1, Homologous recombination, Chickens, HeLa Cells, Nucleotide excision repair
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bfc2d9482c1081d4e16b4edce4d2fcaTest
https://doi.org/10.1128/mcb.24.24.10733-10741.2004Test -
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المؤلفون: Noel F. Lowndes, David G. Schatz, Jean-Marie Buerstedde
المصدر: eLife
eLife, Vol 3 (2014)مصطلحات موضوعية: homologous recombination, Mice, Cytidine deamination, Genes, Reporter, Holliday junction, Activation-induced (cytidine) deaminase, AID, Crossing Over, Genetic, Biology (General), Heteroduplex formation, Sequence Deletion, Genetics, B-Lymphocytes, biology, General Neuroscience, Nucleic Acid Heteroduplexes, General Medicine, Non-homologous end joining, Medicine, Research Article, QH301-705.5, Science, chicken, Immunology, Green Fluorescent Proteins, Molecular Sequence Data, Non-allelic homologous recombination, Gene Conversion, DNA repair, General Biochemistry, Genetics and Molecular Biology, Cell Line, Cytidine Deaminase, Sequence Homology, Nucleic Acid, Animals, Humans, Gene conversion, mouse, Repetitive Sequences, Nucleic Acid, General Immunology and Microbiology, Base Sequence, Models, Genetic, Recombinational DNA Repair, Cell Biology, Molecular biology, Immunoglobulin Switch Region, Luminescent Proteins, biology.protein, Somatic Hypermutation, Immunoglobulin, Homologous recombination, Chickens
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11603bff400fd5664c2ec1f6a02dad2Test
http://europepmc.org/articles/PMC4080448Test -
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المؤلفون: David G. Schatz, Jessica J. McDonald, Jean-Marie Buerstedde, Jukka Alinikula, Hiroshi Arakawa
المصدر: PLoS Biology
PLoS Biology, Vol 12, Iss 4, p e1001831 (2014)مصطلحات موضوعية: B Cells, Transcription, Genetic, Lymphocyte Activation, Biochemistry, E-Box Elements, White Blood Cells, Gene Knockout Techniques, Mice, 0302 clinical medicine, Animal Cells, Nucleic Acids, Molecular Cell Biology, Biology (General), Immune Response, 0303 health sciences, B-Lymphocytes, Immune System Proteins, MEF2 Transcription Factors, General Neuroscience, NF-kappa B, Cytidine deaminase, 3. Good health, Enhancer Elements, Genetic, Cellular Types, General Agricultural and Biological Sciences, DNA modification, Research Article, QH301-705.5, Immune Cells, DNA transcription, Immunology, Green Fluorescent Proteins, Somatic hypermutation, Biology, General Biochemistry, Genetics and Molecular Biology, Antibodies, Cell Line, Affinity maturation, 03 medical and health sciences, Immunoglobulin kappa-Chains, Immunoglobulin lambda-Chains, Cytidine Deaminase, Genetics, Animals, Humans, Enhancer, Uracil-DNA Glycosidase, Gene, Transcription factor, 030304 developmental biology, Blood Cells, Binding Sites, General Immunology and Microbiology, Biology and life sciences, Point mutation, Proteins, DNA, Cell Biology, Molecular biology, Mutation, Gene expression, Somatic Hypermutation, Immunoglobulin, Chickens, Sequence Alignment, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a2c7f03381e457777efb988037e9aaTest
http://europepmc.org/articles/PMC3972084Test -
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المؤلفون: Jean-Marie Buerstedde, Andy Law, Paul Geroth, Dmitry Lodygin, Igor Abdrakhmanov, Hiroshi Arakawa, Jiri Plachy, Berndt Korn
المصدر: Genome Research. 10:2062-2069
مصطلحات موضوعية: animal structures, Databases, Factual, Molecular Sequence Data, Biology, computer.software_genre, Bursa of Fabricius, Gene mapping, Sequence Homology, Nucleic Acid, Gene expression, Genetics, Animals, Humans, Database search engine, Lymphocytes, Gene conversion, Gene, Genetics (clinical), Expressed Sequence Tags, Internet, Expressed sequence tag, Genes, Immunoglobulin, Database, Gene Expression Profiling, Computational Biology, Genome project, Resources, Gene expression profiling, Genes, Multigene Family, embryonic structures, Chickens, Sequence Alignment, human activities, computer, Software
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139c52c042b36e2ffb5771be1a79e419Test
https://doi.org/10.1101/gr.10.12.2062Test -
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المؤلفون: Wolf Dietrich Heyer, Roland Kanaar, Jan Huib Franssen, Albert Pastink, Jeroen Essers, Bep Smit, Jean-Marie Buerstedde, Beate Clever, Sigrid M. A. Swagemakers, Jan H.J. Hoeijmakers, Christine Troelstra, Olga Bezzubova
المصدر: Current Biology. 6:828-838
مصطلحات موضوعية: DNA, Complementary, Saccharomyces cerevisiae Proteins, DNA Repair, DNA repair, Molecular Sequence Data, Saccharomyces cerevisiae, Gene Expression, Biology, General Biochemistry, Genetics and Molecular Biology, Conserved sequence, Fungal Proteins, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Complementary DNA, medicine, Animals, Humans, Amino Acid Sequence, Gene, Conserved Sequence, 030304 developmental biology, Genetics, 0303 health sciences, Agricultural and Biological Sciences(all), Base Sequence, Sequence Homology, Amino Acid, Biochemistry, Genetics and Molecular Biology(all), Genetic Complementation Test, fungi, DNA Helicases, Chromosome Mapping, Nuclear Proteins, biology.organism_classification, DNA-Binding Proteins, DNA Repair Enzymes, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, COS Cells, General Agricultural and Biological Sciences, Homologous recombination, Germ cell, DNA, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de07137bfef88fac4da35de706fe2f4bTest
https://doi.org/10.1016/s0960-9822Test(02)00606-1 -
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المؤلفون: Jean-Marie, Buerstedde, Hiroshi, Arakawa
المصدر: Sub-cellular biochemistry. 40
مصطلحات موضوعية: Recombination, Genetic, B-Lymphocytes, Mice, Genes, Immunoglobulin, Mutation, Gene Conversion, Animals, Humans, Chickens, Cell Line
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::cd6d6beb29f274b1d988daa4beb47484Test
https://pubmed.ncbi.nlm.nih.gov/17623897Test