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المؤلفون: Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D. Smith, Francesco Forconi, Bauke V. Schomakers, Michel van Weeghel, Dean J. Bryant, Jaco A. C. van Bruggen, Fleur S. Peters, Jeffrey C. Rathmell, Gerritje J. W. van der Windt, Arnon P. Kater, Graham Packham, Eric Eldering
المساهمون: Graduate School, CCA - Cancer biology and immunology, Experimental Immunology, Laboratory Genetic Metabolic Diseases, ACS - Diabetes & metabolism, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Clinical Haematology, Hematology
المصدر: Blood, 140(6), 630-643. American Society of Hematology
Chen, Z, Simon-Molas, H, Cretenet, G, Valle-Argos, B, Smith, L D, Forconi, F, Schomakers, B V, van Weeghel, M, Bryant, D J, van Bruggen, J A C, Peters, F S, Rathmell, J C, van der Windt, G J W, Kater, A P, Packham, G & Eldering, E 2022, ' Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment ', Blood, vol. 140, no. 6, pp. 630-643 . https://doi.org/10.1182/blood.2021013990Testمصطلحات موضوعية: Glucose, Glutamine, hemic and lymphatic diseases, Immunology, Tumor Microenvironment, Humans, Receptors, Antigen, B-Cell, Lymph Nodes, Cell Biology, Hematology, CD40 Antigens, Leukemia, Lymphocytic, Chronic, B-Cell, Biochemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94178f7d4262014e777d0dddbec2e94eTest
http://www.scopus.com/inward/record.url?scp=85132192009&partnerID=8YFLogxKTest -
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المؤلفون: Andrew J. Steele, Freda K. Stevenson, Joe Taylor, Mark J. Coldwell, Graham Packham, Sarah Wilmore, Elizabeth Lemm, Alison Yeomans, Francesco Forconi, Rachel Fell, Karly-Rai Rogers-Broadway
المصدر: Cellular and Molecular Life Sciences
مصطلحات موضوعية: mRNA translation, RNA Stability, Chronic lymphocytic leukemia, B-cell receptor, Receptors, Antigen, B-Cell, MYC, Silvestrol, Proto-Oncogene Proteins c-myc, Cellular and Molecular Neuroscience, hemic and lymphatic diseases, medicine, Humans, Initiation factor, MCL1, RNA, Messenger, Molecular Biology, Cells, Cultured, Benzofurans, Pharmacology, Chemistry, breakpoint cluster region, Translation (biology), Cell Biology, MRNA stabilization, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Triterpenes, Antibodies, Anti-Idiotypic, Protein Biosynthesis, eIF4A, Eukaryotic Initiation Factor-4A, Leukocytes, Mononuclear, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Molecular Medicine, Original Article, Rocaglamide, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bb8b1f4d8bff40a8702adbd37299e5Test
https://doi.org/10.1007/s00018-021-03910-xTest -
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المؤلفون: Bradleigh Whitton, Simon J. Crabb, Graham Packham, Matthew J. J. Rose-Zerilli, Haruko Okamoto
المصدر: Mol Cancer Ther
مصطلحات موضوعية: Male, 0301 basic medicine, Vacuolar Proton-Translocating ATPases, Cancer Research, medicine.drug_class, Mutant, Transfection, Article, 03 medical and health sciences, Prostate cancer, chemistry.chemical_compound, 0302 clinical medicine, Proton transport, LNCaP, medicine, Humans, Enzalutamide, Chemistry, Androgen, medicine.disease, Androgen receptor, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, Oncology, Receptors, Androgen, 030220 oncology & carcinogenesis, Cancer research
وصف الملف: text
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2258dbd34508ac55067b95975e8e72b6Test
https://doi.org/10.1158/1535-7163.mct-20-0662Test -
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المؤلفون: Stuart A. Rushworth, Arasu Ganesan, Simon J. Crabb, Kristian M. Bowles, Maria Teresa Borrello, Graham Packham, Hanae Benelkebir, Manar S. Shafat, Sarah G. Bailey, Patrick J. Duriez, Chak Hin Tam, Adam Lee, Leon Douglas
المصدر: ChemMedChem. 16:1316-1324
مصطلحات موضوعية: animal structures, Cell Survival, medicine.drug_class, Antineoplastic Agents, Carboxamide, Pharmacology, 01 natural sciences, Biochemistry, Cell Line, Tumor, Drug Discovery, medicine, Humans, Enzyme Inhibitors, General Pharmacology, Toxicology and Pharmaceutics, Cell Proliferation, Histone Demethylases, biology, 010405 organic chemistry, Chemistry, Cell growth, Organic Chemistry, Tranylcypromine, Myeloid leukemia, KDM1A, Prodrug, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Cell culture, biology.protein, Molecular Medicine, Demethylase, Drug Screening Assays, Antitumor, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::666ccb179d2deaae73378780b6870138Test
https://doi.org/10.1002/cmdc.202000754Test -
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المؤلفون: Rachael Arthur, Alexander Wathen, Elizabeth A. Lemm, Freda K. Stevenson, Francesco Forconi, Adam J. Linley, Andrew J. Steele, Graham Packham, Beatriz Valle-Argos
المصدر: Cellular signalling. 96
مصطلحات موضوعية: Pyrimidines, Drug Resistance, Neoplasm, Phospholipase C gamma, Agammaglobulinaemia Tyrosine Kinase, Humans, Pyrazoles, Receptors, Antigen, B-Cell, Calcium, Cell Biology, Leukemia, Lymphocytic, Chronic, B-Cell, Protein Kinase Inhibitors
وصف الملف: text
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637a9ccc108d7f99db732583cec3dea1Test
https://pubmed.ncbi.nlm.nih.gov/35597428Test -
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المؤلفون: Joe Taylor, Sarah Wilmore, Sophie Marriot, Karly-Rai Rogers-Broadway, Rachel Fell, Annabel R. Minton, Tom Branch, Meg Ashton-Key, Mark Coldwell, Freda K. Stevenson, Francesco Forconi, Andrew J. Steele, Graham Packham, Alison Yeomans
المصدر: Cellular signalling. 94
مصطلحات موضوعية: Humans, RNA-Binding Proteins, Receptors, Antigen, B-Cell, Cell Biology, Mechanistic Target of Rapamycin Complex 1, Apoptosis Regulatory Proteins, Leukemia, Lymphocytic, Chronic, B-Cell, Proto-Oncogene Proteins c-akt, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d011cd9be1c649d6c8ad263a5014d5Test
https://pubmed.ncbi.nlm.nih.gov/35306137Test -
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المؤلفون: Dean Bryant, George E. Wright, James S. Blachly, Jonathan C. Strefford, Graham Packham, Carl G. Figdor, Francesco Forconi, Isla Henderson, Thomas A. Bowden, Giorgia Chiodin, Teunis B. H. Geijtenbeek, Beatriz Valle-Argos, Philip J. Rock, Enrica Antonia Martino, Patrick J. Duriez, Freda K. Stevenson, Yasunori Watanabe, Katy J. McCann, Louis M. Staudt, Max Crispin, Joel D. Allen, Richard Burack
المساهمون: AII - Cancer immunology, Experimental Immunology, Infectious diseases, CCA - Cancer biology and immunology
المصدر: Blood, 138(17), 1570-1582. American Society of Hematology
Blood, 138, 17, pp. 1570-1582
Blood, 138, 1570-1582
Bloodمصطلحات موضوعية: Glycosylation, Surface Immunoglobulin, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Immunology, Follicular lymphoma, Receptors, Antigen, B-Cell, Receptors, Cell Surface, Biology, Biochemistry, chemistry.chemical_compound, Polysaccharides, hemic and lymphatic diseases, medicine, Tumor Cells, Cultured, Humans, Lectins, C-Type, Protein Interaction Domains and Motifs, PI3K/AKT/mTOR pathway, Lymphoid Neoplasia, Binding Sites, Germinal center, Cell Biology, Hematology, medicine.disease, Complementarity Determining Regions, Tumor antigen, Lymphoma, chemistry, biology.protein, Cancer research, Lymphoma, Large B-Cell, Diffuse, Antibody, Sugars, Cell Adhesion Molecules
وصف الملف: text
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29c1bc1823f404e2a7f19678b1ca290Test
https://hdl.handle.net/2066/244632Test -
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المؤلفون: Karina Close, Jun Wang, Tahrima Rahim, Sameena Iqbal, Findlay Bewicke-Copley, Andrew Clear, Martin Philpott, Annalisa D'Avola, Lola Konali, James A. Heward, Emil Kumar, Udo Oppermann, Richard Neve, Maria Calaminici, Pedro R. Cutillas, Jessica Okosun, Peter Johnson, Koorosh Korfi, John G. Gribben, Darko Barisic, Ahad F. Al Seraihi, James E. Dunford, Alison Yeomans, Ari Melnick, Shamzah Araf, Jude Fitzgibbon, Graham Packham
المصدر: Blood
مصطلحات موضوعية: 0301 basic medicine, Immunology, Mutant, medicine.disease_cause, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Loss of Function Mutation, Cell Line, Tumor, Gene expression, medicine, Animals, Humans, Enzyme Inhibitors, Mutation, biology, Chemistry, Germinal center, Cell Biology, Hematology, Methylation, medicine.disease, Xenograft Model Antitumor Assays, Neoplasm Proteins, Lymphoma, DNA-Binding Proteins, 030104 developmental biology, Histone, biology.protein, Cancer research, H3K4me3, Lymphoma, Large B-Cell, Diffuse, Erratum, Retinoblastoma-Binding Protein 2, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69f75b8e11d8e8cb74d2e87d8a74550Test
https://ora.ox.ac.uk/objects/uuid:7efc616c-0a6f-4725-8739-6ff679a99852Test -
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المؤلفون: Francesco Forconi, Giorgia Chiodin, Jonathan C. Strefford, Freda K. Stevenson, Graham Packham, Richard Burack, Beatriz Valle-Argos, Joe Taylor, Dean Bryant, Elizabeth Lemm, Patrick J. Duriez, Philip J. Rock
المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)مصطلحات موضوعية: 0301 basic medicine, Receptors, CXCR4, Glycosylation, Surface Immunoglobulin, Science, Cell, B-cell receptor, Follicular lymphoma, Receptors, Antigen, B-Cell, Somatic hypermutation, Receptors, Cell Surface, Article, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, Lectins, C-Type, Calcium Signaling, Receptor, Lymphoma, Follicular, Cancer, Multidisciplinary, biology, Chemistry, Calcium signalling, medicine.disease, Cell biology, Gene Expression Regulation, Neoplastic, DC-SIGN, 030104 developmental biology, medicine.anatomical_structure, Immunoglobulin M, Cell culture, 030220 oncology & carcinogenesis, biology.protein, Medicine, Tumour immunology, Calcium, Gene expression, Cell Adhesion Molecules, Cell signalling, Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac055fc18ce80b4078979b7fe6090b9aTest
https://doi.org/10.1038/s41598-021-91112-7Test -
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المؤلفون: David J. MacEwan, Graham Packham, Francesco Forconi, Adam Linley, Nagesh Kalakonda, Andy C. Rawstron, Joseph R. Slupsky, Laura I. Karydis, Annalisa D'Avola, Andrew R. Pettitt, R.C. Griffin, Anil K. Mondru, Silvia Cicconi, Humood Al Shmrany, Peter Hillmen, Andrew J. Steele, Ian A. Prior
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 27(20)
مصطلحات موضوعية: Cancer Research, Chronic lymphocytic leukemia, Cytological Techniques, chemistry.chemical_compound, Chemoimmunotherapy, hemic and lymphatic diseases, medicine, Tumor Cells, Cultured, Humans, Kinome, KEGG, Protein Kinase Inhibitors, B-Lymphocytes, Kinase, business.industry, breakpoint cluster region, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Microspheres, Oncology, chemistry, Ibrutinib, Cancer research, business, Reprogramming, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ffcef31d1a2a11f02ca1a1e23a1618Test
https://pubmed.ncbi.nlm.nih.gov/34380642Test