المؤلفون: René Bernards, Giulia De Conti, Lenno Krenning, Ziva Pogacar, Marieke van de Ven, Cor Lieftink, Arnout Schepers, Jackie Johnson, Arno Velds, Olaf van Tellingen, Kelvin Groot, Roderick L. Beijersbergen, Rodrigo Leite de Oliveira, Ji-Ying Song, Fleur Jochems, René H. Medema, Leyma Wardak, Liqin Wang

المساهمون: Human genetics

المصدر: PLoS ONE, 17(9 September):e0273182. Public Library of Science
Pogacar, Z, Johnson, J L, Krenning, L, de Conti, G, Jochems, F, Lieftink, C, Velds, A, Wardak, L, Groot, K, Schepers, A, Wang, L, Song, J-Y, van de Ven, M, van Tellingen, O, Medema, R H, Beijersbergen, R L, Bernards, R & Leite de Oliveira, R 2022, ' Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity ', PLoS ONE, vol. 17, no. 9 September, e0273182, pp. e0273182 . https://doi.org/10.1371/journal.pone.0273182Test

مصطلحات موضوعية: Senescence, Sulfonamides, Multidisciplinary, biology, Chemistry, Pyridines, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Palbociclib, Piperazines, Downregulation and upregulation, Cell culture, Cell Line, Tumor, Cancer cell, Cancer research, biology.protein, Humans, biological phenomena, cell phenomena, and immunity, Kinase activity, Senolytic, Protein Kinase Inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a29ef97e9ee3d0ca0f36662417d453aTest
http://www.scopus.com/inward/record.url?scp=85137745306&partnerID=8YFLogxKTest

المؤلفون: Rodrigo Leite de Oliveira, Giulia De Conti, Cor Lieftink, Arnout Schepers, Roderick L. Beijersbergen, René Bernards, Ziva Pogacar, Fleur Jochems, Liqin Wang

المصدر: Mol Cancer Res

مصطلحات موضوعية: Senescence, Cancer Research, Autophagy-Related Proteins, Apoptosis, Biology, Article, Cell Line, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Neoplasms, Autophagy, medicine, Autophagy-Related Protein-1 Homolog, Humans, CRISPR, Senolytic, Molecular Biology, Cellular Senescence, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Cancer, ULK1, medicine.disease, HEK293 Cells, Oncology, A549 Cells, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, CRISPR-Cas Systems

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab7c3c161e6fd4bc1fdc9b4e06ac955Test
https://doi.org/10.1158/1541-7786.mcr-21-0146Test