المؤلفون: Kip P. Conner, Min-Zu Wu, Jiamiao Lu, Aazam Ghelani, Yi-Ling Hu, Darren L. Bates, Ashutosh Chaudhry, Sue J. Sohn, Chi-Ming Li

المصدر: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, 0301 basic medicine, Immunology, Lymphocyte Activation, Protein Engineering, T-Lymphocytes, Regulatory, law.invention, 03 medical and health sciences, Mice, Structure-Activity Relationship, 0302 clinical medicine, law, In vivo, Immunology and Allergy, Animals, Humans, IL-2 receptor, Receptor, STAT5, Original Research, tolerance, biology, Chemistry, IL-2, autoimmunity, In vitro, Recombinant Proteins, regulatory T, Cell biology, Treg, 030104 developmental biology, inflammation, Humanized mouse, biology.protein, Suppressor, Phosphorylation, Interleukin-2, mutein, lcsh:RC581-607, 030215 immunology, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5300a7e9e52e6055f1cfa65656b9afTest
https://pubmed.ncbi.nlm.nih.gov/32582190Test

المؤلفون: Brandon C. P. Clavette, Xiaoshan Min, Joanne Lin, Elizabeth A. Killion, Robert J.M. Kurzeja, David Lloyd, Liying Deng, Zhulun Wang, Clarence Hale, Christopher Murawsky, Stone D.-H. Shi, Murielle M. Véniant, Jinghong Wang, James B. Rottman, Christina Abbott, Todd Hager, Lu Shu Chen, Junming Yie, Ian Foltz, Qing Chen, Stephen A. Thibault, Darren L. Bates, Renee Komorowski, Larissa Atangan, Glenn Sivits, Tina Meng

المصدر: Science Translational Medicine. 10

مصطلحات موضوعية: Primates, 0301 basic medicine, endocrine system, medicine.medical_specialty, Recombinant Fusion Proteins, Glucagon-Like Peptides, Mice, Obese, Genome-wide association study, Gastric Inhibitory Polypeptide, Weight Gain, Antibodies, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, 0302 clinical medicine, Weight loss, Insulin-Secreting Cells, Internal medicine, Weight Loss, Conditional gene knockout, Adipocytes, Animals, Humans, Medicine, Obesity, Receptor, Respiratory exchange ratio, biology, business.industry, Respiration, Feeding Behavior, General Medicine, Liraglutide, medicine.disease, Diet, Immunoglobulin Fc Fragments, 030104 developmental biology, Endocrinology, 030220 oncology & carcinogenesis, Knockout mouse, biology.protein, Drug Therapy, Combination, medicine.symptom, Antibody, business, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4219a5cd6927493203264b2541e2f88bTest
https://doi.org/10.1126/scitranslmed.aat3392Test

المؤلفون: Ite A. Laird-Offringa, Po Han Chen, Lin Chen, Ana Carolina Dantas Machado, Yongheng Chen, Remo Rohs, Darren L. Bates, Raja Dey

المصدر: Cell Reports, Vol 2, Iss 5, Pp 1197-1206 (2012)

مصطلحات موضوعية: Molecular Sequence Data, Biology, Crystallography, X-Ray, GATA Transcription Factors, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chemistry.chemical_compound, Transcription (biology), Fluorescence Resonance Energy Transfer, Humans, Amino Acid Sequence, lcsh:QH301-705.5, 030304 developmental biology, Zinc finger, 0303 health sciences, Binding Sites, Base Sequence, 030302 biochemistry & molecular biology, GATA2, GATA3, Zinc Fingers, DNA, DNA-binding domain, Molecular biology, Protein Structure, Tertiary, Cell biology, DNA binding site, Gene Expression Regulation, lcsh:Biology (General), chemistry, GATA transcription factor, Sequence Alignment, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f279d5e267bf9c3088e357f4944b9b35Test
https://doi.org/10.1016/j.celrep.2012.10.012Test

المؤلفون: Lin Chen, James C. Stroud, Aidong Han, Amy Oltman, Darren L. Bates

المصدر: Journal of Molecular Biology. 393:98-112

مصطلحات موضوعية: Models, Molecular, viruses, Transcription Factor RelA, Plasma protein binding, Biology, Crystallography, X-Ray, Article, Conserved sequence, chemistry.chemical_compound, Structural Biology, Transcription (biology), Humans, Protein Structure, Quaternary, Molecular Biology, HIV Long Terminal Repeat, NF-kappa B p50 Subunit, Molecular biology, Long terminal repeat, Cell biology, chemistry, DNA, Viral, Host-Pathogen Interactions, HIV-1, Virus Activation, Protein Multimerization, DNA, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdab608386c8f926624f26291d4ea76Test
https://doi.org/10.1016/j.jmb.2009.08.023Test

المؤلفون: Kristen K. B. Barthel, Reza Kalhor, James C. Stroud, Lin Chen, Michael J. Giffin, Darren L. Bates, Yongqing Wu

المصدر: Structure. 16:684-694

مصطلحات موضوعية: Models, Molecular, Biology, Crystallography, X-Ray, Article, Structural Biology, Humans, Computer Simulation, Binding site, Enhancer, Molecular Biology, Transcription factor, HIV Long Terminal Repeat, Binding Sites, NFATC Transcription Factors, NF-kappa B, NFAT, DNA, DNA-binding domain, Molecular biology, Recombinant Proteins, Long terminal repeat, Protein Structure, Tertiary, Cell biology, Enhancer Elements, Genetic, HIV-1, Nucleic Acid Conformation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d73261b6b4e9fa2fc0f5787a2aa809Test
https://doi.org/10.1016/j.str.2008.01.020Test

المؤلفون: Katja Nowick, Darren L. Bates, James C. Stroud, Lin Chen, Yongqing Wu, Svante Pääbo, Aidong Han, Harry Tong

المصدر: Structure

مصطلحات موضوعية: Genetics, Mutation, Subfamily, HMG-box, Molecular Sequence Data, Forkhead Transcription Factors, FOX proteins, Biology, Crystallography, X-Ray, medicine.disease_cause, Protein Structure, Tertiary, DNA-Binding Proteins, Forkhead box L2, Structural Biology, medicine, Humans, Amino Acid Sequence, Forkhead box C1, FOXA2, FOXD3, Dimerization, Molecular Biology, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894cb735ea6b5e7588ddc7fecba663d2Test

المؤلفون: Lin Chen, Konstanze D von Koenig, Darren L. Bates, Michael J. Giffin, John W. Hardin, James C. Stroud

المصدر: Nature Structural & Molecular Biology. 10:800-806

مصطلحات موضوعية: NFATC Transcription Factors, Stereochemistry, Dimer, Molecular Sequence Data, Nuclear Proteins, NFAT, Context (language use), Crystal structure, Biology, Molecular biology, Long terminal repeat, Protein Structure, Tertiary, DNA-Binding Proteins, chemistry.chemical_compound, Monomer, chemistry, Structural Biology, NFAT5, Humans, Amino Acid Sequence, Dimerization, Molecular Biology, DNA, HIV Long Terminal Repeat, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90839a4c11e76c7be64e71f00066fa44Test
https://doi.org/10.1038/nsb981Test

المؤلفون: Aron M. Levin, K. Christopher Garcia, Paul Novick, Aaron M. Ring, Miro E. Raeber, Leon Su, Jack T. Lin, Gregory R. Bowman, C. Garrison Fathman, Onur Boyman, Vijay S. Pande, Darren L. Bates, Carsten Krieg, Ignacio Moraga

المساهمون: University of Zurich, Garcia, K Christopher

المصدر: Nature

مصطلحات موضوعية: Models, Molecular, Receptor complex, Protein Conformation, medicine.medical_treatment, T-Lymphocytes, Crystallography, X-Ray, Protein Engineering, Mice, 0302 clinical medicine, Neoplasms, STAT5 Transcription Factor, Cytotoxic T cell, IL-2 receptor, Phosphorylation, 0303 health sciences, Multidisciplinary, ZAP70, 10177 Dermatology Clinic, 3. Good health, Cell biology, Killer Cells, Natural, Cytokine, Immunotherapy, medicine.drug, Interleukin 2, 610 Medicine & health, Streptamer, Biology, Molecular Dynamics Simulation, Article, Cell Line, 03 medical and health sciences, Immune system, medicine, Animals, Humans, 030304 developmental biology, Cell Proliferation, 1000 Multidisciplinary, Binding Sites, Interleukin-2 Receptor alpha Subunit, Surface Plasmon Resonance, Molecular biology, Interleukin-2 Receptor beta Subunit, Mice, Inbred C57BL, Mutation, Interleukin-2, Mutant Proteins, Directed Molecular Evolution, Neoplasm Transplantation, 030215 immunology

وصف الملف: Levin_et_al._-_Nature_2012.pdf - application/pdf; Levin_et_al_Acc-MS.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c841d44ba8335e8595f4cd275c74e2c2Test
https://doi.org/10.5167/uzh-75564Test

المؤلفون: Jue Cao, Aidong Han, Lin Chen, Liang Guo, Darren L. Bates

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Glutamine, Molecular Sequence Data, Plasma protein binding, Biology, Crystallography, X-Ray, Histone Deacetylases, Protein Structure, Secondary, chemistry.chemical_compound, Protein structure, Tetramer, Humans, Amino Acid Sequence, Peptide sequence, Coiled coil, Multidisciplinary, Sequence Homology, Amino Acid, Biological Sciences, Hydrogen-Ion Concentration, HDAC4, Protein Structure, Tertiary, Repressor Proteins, Crystallography, Monomer, chemistry, Mutagenesis, Biophysics, Sequence motif, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfeaa0e5a9aebeaee4438a555c80624Test
https://europepmc.org/articles/PMC1838596Test/

المؤلفون: Steven F. Ziegler, Ariya D. Lapan, Liang Guo, Vigo Heissmeyer, Christophe Benoist, Diane Mathis, Darren L. Bates, James C. Stroud, Anjana Rao, Lin Chen, Yongqing Wu, Madhuri Borde, Markus Feuerer, Aidong Han

المصدر: Cell 126, 375-387 (2006)

مصطلحات موضوعية: Models, Molecular, Regulatory T cell, T cell, Molecular Sequence Data, Regulator, chemical and pharmacologic phenomena, Biology, Crystallography, X-Ray, Jurkat cells, T-Lymphocytes, Regulatory, General Biochemistry, Genetics and Molecular Biology, Jurkat Cells, Mice, Genes, Reporter, Mice, Inbred NOD, medicine, Animals, Humans, IL-2 receptor, Amino Acid Sequence, Luciferases, Transcription factor, Cells, Cultured, Binding Sites, NFATC Transcription Factors, Sequence Homology, Amino Acid, Biochemistry, Genetics and Molecular Biology(all), FOXP3, hemic and immune systems, NFAT, Forkhead Transcription Factors, Receptors, Interleukin-2, Recombinant Proteins, Protein Structure, Tertiary, Up-Regulation, Repressor Proteins, medicine.anatomical_structure, Retroviridae, Amino Acid Substitution, Cancer research, Interleukin-2, Dimerization, Biomarkers, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cf2739206bc744d4ba66f6b7761f55Test
https://pubmed.ncbi.nlm.nih.gov/16873058Test