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المؤلفون: Katharina Rothe, Artem Babaian, Keith Keith Humphries, Jonathan Zeng, Xiaoyan Jiang, Min Chen, Donna L. Forrest, Hanyang Lin, Oleh Petriv, Inanc Birol, Connie J. Eaves, Jens Ruschmann, Tobias Maetzig, Ryan R. Brinkman, David J.H.F. Knapp, Naoto Nakamichi, Kieran O'Neill, Carl L. Hansen, Ryan Yen, Andrew Wu
المصدر: Blood
مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Xenotransplantation, medicine.medical_treatment, Immunology, Mice, SCID, Drug resistance, Biology, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Cancer stem cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, microRNA, medicine, Animals, Humans, Progenitor cell, Protein Kinase Inhibitors, Myeloid Neoplasia, Gene Expression Regulation, Leukemic, Myeloid leukemia, Cell Biology, Hematology, MicroRNAs, 030104 developmental biology, p21-Activated Kinases, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Cancer research, Heterografts, Stem cell, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244fcbe5e7d9ca676c08de606117ab56Test
https://doi.org/10.1182/blood.2019003636Test -
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المؤلفون: Kathryn Westendorf, Stefanie Žentelis, Lingshu Wang, Denisa Foster, Peter Vaillancourt, Matthew Wiggin, Erica Lovett, Robin van der Lee, Jörg Hendle, Anna Pustilnik, J. Michael Sauder, Lucas Kraft, Yuri Hwang, Robert W. Siegel, Jinbiao Chen, Beverly A. Heinz, Richard E. Higgs, Nicole L. Kallewaard, Kevin Jepson, Rodrigo Goya, Maia A. Smith, David W. Collins, Davide Pellacani, Ping Xiang, Valentine de Puyraimond, Marketa Ricicova, Lindsay Devorkin, Caitlin Pritchard, Aoise O’Neill, Kush Dalal, Pankaj Panwar, Harveer Dhupar, Fabian A. Garces, Courtney A. Cohen, John M. Dye, Kathleen E. Huie, Catherine V. Badger, Darwyn Kobasa, Jonathan Audet, Joshua J. Freitas, Saleema Hassanali, Ina Hughes, Luis Munoz, Holly C. Palma, Bharathi Ramamurthy, Robert W. Cross, Thomas W. Geisbert, Vineet Menacherry, Kumari Lokugamage, Viktoriya Borisevich, Iliana Lanz, Lisa Anderson, Payal Sipahimalani, Kizzmekia S. Corbett, Eun Sung Yang, Yi Zhang, Wei Shi, Tongqing Zhou, Misook Choe, John Misasi, Peter D. Kwong, Nancy J. Sullivan, Barney S. Graham, Tara L. Fernandez, Carl L. Hansen, Ester Falconer, John R. Mascola, Bryan E. Jones, Bryan C. Barnhart
المصدر: bioRxiv
مصطلحات موضوعية: chemistry.chemical_classification, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Antibodies, Monoclonal, Biology, Vaccine efficacy, Antibodies, Viral, Virology, Antibodies, Neutralizing, Epitope, Virus, General Biochemistry, Genetics and Molecular Biology, Article, COVID-19 Drug Treatment, Epitopes, chemistry, biology.protein, Potency, Humans, Symptom onset, Antibody, Glycoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb8cf2c168e04af64aeb77ae8c382f6Test
https://europepmc.org/articles/PMC8109210Test/ -
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المؤلفون: Karine Hervé, Carl L. Hansen, Yeeting E. Chong, Luke Burman, Kaitlyn Rauch, David W Collins, Leslie A. Nangle, Stephanie Pfaffen, Kevin A. Heyries, Anders Klaus, David J. King, Sherie Duncan, Kristina Hamel
المصدر: mAbs
article-version (VoR) Version of Recordمصطلحات موضوعية: medicine.drug_class, Somatic cell, Immunology, Antibody Affinity, Somatic hypermutation, autoimmune disease, Biology, Monoclonal antibody, medicine.disease_cause, Epitope, Histidine-tRNA Ligase, Affinity maturation, Report, antibody, medicine, Immunology and Allergy, Humans, protein evolution, cellular immune response, Autoantibodies, Genetics, Mutation, Myositis, repertoire, Antibodies, Monoclonal, bioinformatics, single cell, biology.protein, Immunologic Techniques, Somatic Hypermutation, Immunoglobulin, Aminoacyl tRNA synthetase, Antibody, Clone (B-cell biology)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba2e8472152310fbe9b13f76cb0c9b2Test
https://pubmed.ncbi.nlm.nih.gov/33131414Test -
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المؤلفون: Oleh Petriv, Jens Ruschmann, Edith Schneider, Lars Palmqvist, Kathrin Krowiorz, Anna Staffas, Erik Delsing Malmberg, Carl L. Hansen, Hartmut Döhner, Arefeh Rouhi, Florian Kuchenbauer, Martin Hirst, Arghavan Ashouri, Ping Xiang, Michael Heuser, Konstanze Döhner, Stella Yuan Wei, Lars Bullinger, Christina Miller, Linda Röhner, Nicole Pochert, R. Keith Humphries, Laleh S. Arabanian, Alireza Heravi-Moussavi, Christian Buske, Linda Fogelstrand
المصدر: Haematologica
مصطلحات موضوعية: 0301 basic medicine, Acute Myeloid Leukemia, Carcinogenesis, Article, Pathogenesis, 03 medical and health sciences, Mice, 0302 clinical medicine, In vivo, hemic and lymphatic diseases, microRNA, Medicine, Animals, Humans, Myeloid Ecotropic Viral Integration Site 1 Protein, Homeodomain Proteins, Oncogene, business.industry, Gene Expression Regulation, Leukemic, Myeloid leukemia, Hematology, medicine.disease, Pathophysiology, Leukemia, Leukemia, Myeloid, Acute, MicroRNAs, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, business, Homing (hematopoietic)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e0e72d1b0ec5d74e7282eea9068a83Test
http://europepmc.org/articles/PMC5792269Test -
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المؤلفون: Edward S. Boyden, Elizabeth A. Chavez, Steven S.S. Poon, Robby Becker, Wendy Greenwood, M Jafar Taghiyar, Peter Eirew, Maximillian Lee, Carl L. Hansen, Hans Zahn, Sohrab P. Shah, Mohammad Al Sa’d, Jonas Windager, Maia A. Smith, Lauren Martin, Hsuan Lee, Matt Wiens, So Ra Lee, A. Dariush, Oleg Golovko, Fergus Cafferty, Sorhab Shah, Russell Kunes, Owen Harris, Nick Chornay, Jean Fan, Samuel Aparicio, Marco A. Marra, Shankar Balasubramanian, Stephen Chia, Andrew McPherson, Farhia Kabeer, Samantha Leung, Sophia A Wild, Neil Millar, Claire Mulvey, Shahar Alon, Giorgia Battistoni, Leonardo Sepulveda Duran, Anubhav Sinha, Khanh N. Dinh, Viktoria Bojilova, Yi Cui, Nafis Abrar, Sophia Chan, Yussanne Ma, Austin Smith, Marcel Burger, Jean Hausser, Eduardo Gonzales Solares, Maurizio Callari, Bernd Bodenmiller, Dario Bressan, Aybuke Kupcu Yoldas, Tehmina Masud, Adi Steif, Colin Mar, Abigail Shea, Gregory J. Hannon, Yangguang Li, Timothy M. Chan, Christian Steidl, Cydney B. Nielsen, Flaminia Grimaldi, Eyal Fisher, Daniel J. Da Costa, Tatjana Kovacevic, Carlos Gonzalez-Fernandez, Beixi Wang, Spencer Watson, Sandra Tietscher, Teresa Ruiz, Ignacio Vázquez-García, Jessica Ngo, Amauche Emenari, Pu Zheng, Kirsty Sawicka, Carlos Caldas, Asmamaw T Wassie, Daniel Lai, Chenglong Xia, Oscar M. Rueda, Robin J.N. Coope, Andrew J. Mungall, Fiona Nugent, Marta Paez Ribes, Karen A. Gelmon, Stephen Pleasance, Simon Tavaré, Pascale Walters, Teresa Ruiz de Algara, Ciara H. O'Flanagan, Curtis Huebner, Emma Laks, T. Michael Underhill, Jazmine Brimhall, Alastair Marti, Justina Biele, R. Wilder Scott, Diljot Grewal, Fatime Qosaj, Richard D. Moore, Dan Goodwin, Laura Kuett, Nicolas A. Walton, Suvi Harris, Emmanouil D. Karagiannis, Cristina Jauset, Elena Williams, Isabella Pearsall, Sara Vogl, Alejandra Bruna, Yaniv Lubling, Jerome Ting, Ian G. Cannell, Xiaowei Zhuang, Richard Corbett, Hannah Casbolt, Giulia Lerda, Johanna A. Joyce, Spencer Vatrt-Watts
المصدر: Elsevier
Cellمصطلحات موضوعية: Genome instability, DNA Replication, Male, tumor evolution, Genotype, Cell Survival, Genomics, Computational biology, Biology, Genome, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, DNA sequencing, 03 medical and health sciences, Mice, 0302 clinical medicine, copy number, Cell Line, Tumor, tumor heterogeneity, Animals, Chromosomes, Human, Humans, Cell Shape, Phylogeny, 030304 developmental biology, cancer genomics, 0303 health sciences, Genome, Human, Cell Cycle, DNA replication, High-Throughput Nucleotide Sequencing, Cell cycle, genomic instability, Aneuploidy, Diploidy, single cell, Clone Cells, Mutation, DNA Transposable Elements, Female, Ploidy, Single-Cell Analysis, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93887a330b47f0bff283dbfe67150265Test
https://pubmed.ncbi.nlm.nih.gov/31907478Test -
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المؤلفون: Martin Hirst, Kaston Leung, Daniel Lai, Adi Steif, Yi-Fei Huang, Anders Klaus, Justina Biele, Ali Bashashati, Bill K. Lin, Anne Marie Mes-Masson, Samuel Aparicio, Emma Laks, Michelle Moksa, Radhouane Aniba, Carl L. Hansen, Sohrab P. Shah
المصدر: Proceedings of the National Academy of Sciences. 113:8484-8489
مصطلحات موضوعية: 0301 basic medicine, DNA Copy Number Variations, Computational biology, Biology, Polymorphism, Single Nucleotide, Deep sequencing, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Single-cell analysis, Cell Line, Tumor, Humans, Copy-number variation, Alleles, Whole genome sequencing, Whole Genome Amplification, Genetics, Multidisciplinary, Genome, Human, Multiple displacement amplification, High-Throughput Nucleotide Sequencing, Reproducibility of Results, Genomics, Nucleic acid amplification technique, Biological Sciences, 030104 developmental biology, Single cell sequencing, 030220 oncology & carcinogenesis, Single-Cell Analysis, Nucleic Acid Amplification Techniques
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe3cf58e52bb97806419fc059423fc4Test
https://doi.org/10.1073/pnas.1520964113Test -
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المؤلفون: Carl L. Hansen, Hans Zahn, Nicolas J. Caron, James M. Piret, Darek Sikorski, Connie J. Eaves, Michael VanInsberghe
المصدر: Biotechnology Journal. 10:1546-1554
مصطلحات موضوعية: Pluripotent Stem Cells, Human Embryonic Stem Cells, Microfluidics, Cell, Cell Culture Techniques, Biology, 01 natural sciences, Applied Microbiology and Biotechnology, Clonal analysis, Genetic Heterogeneity, 03 medical and health sciences, Perfusion Culture, medicine, Humans, Cell Lineage, reproductive and urinary physiology, Clonal growth, Cell Proliferation, 030304 developmental biology, 0303 health sciences, 010401 analytical chemistry, Cell Differentiation, General Medicine, Microfluidic Analytical Techniques, Flow Cytometry, Embryonic stem cell, Molecular biology, 0104 chemical sciences, Cell biology, medicine.anatomical_structure, Cytoplasm, embryonic structures, Molecular Medicine, biological phenomena, cell phenomena, and immunity
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56de5fb0ce9ac9b88ba0f4d2ce8644a6Test
https://doi.org/10.1002/biot.201500035Test -
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المؤلفون: Weijia Wang, Carl L. Hansen, Karen Sachs, Davide Pellacani, Wenlian Qiao, David J.H.F. Knapp, Guy Sauvageau, Sean C. Bendall, Philip A. Beer, Connie J. Eaves, Nima Aghaeepour, Garry P. Nolan, R. Keith Humphries, Peter W. Zandstra, Paul H. Miller, Colin A. Hammond
المصدر: Blood. 129(3)
مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Hematopoiesis and Stem Cells, Immunology, CD34, Stem cell factor, Biology, Biochemistry, Immunophenotyping, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Humans, CD90, Protein kinase B, Interleukin 3, Cell Proliferation, Cell growth, Hematopoietic stem cell, hemic and immune systems, Cell Biology, Hematology, Hematopoietic Stem Cells, Cell biology, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cord blood, Intercellular Signaling Peptides and Proteins, Signal Transduction, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6bb970cd50bfc20a8bbda5da381b36Test
https://pubmed.ncbi.nlm.nih.gov/27827829Test -
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المؤلفون: Adam K. White, Veronique Lecault, Carl L. Hansen, Anupam Singhal
المصدر: Current Opinion in Chemical Biology. 16:381-390
مصطلحات موضوعية: Cell studies, Reverse Transcriptase Polymerase Chain Reaction, business.industry, Drug discovery, Microfluidics, Proteins, Nanotechnology, Genomics, Computational biology, Microfluidic Analytical Techniques, Biology, Biochemistry, Automation, Analytical Chemistry, Single-cell analysis, Analytics, Proteins metabolism, Animals, Humans, Single-Cell Analysis, business, Cell Proliferation
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0281f40a9c5f04a310e49fdb5f5f9319Test
https://doi.org/10.1016/j.cbpa.2012.03.022Test -
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المؤلفون: Cedric A. Brimacombe, Carl L. Hansen, Ivan Sloma, Philip A. Beer, Donna Leung, Kamini Raghuram, Karen Lambie, James M. Piret, Connie J. Eaves, Suzan Imren, Yongjun Zhao, R K Humphries, Veronique Lecault
المصدر: Leukemia
مصطلحات موضوعية: Cancer Research, Oncogene Proteins, Fusion, Cellular differentiation, Fusion Proteins, bcr-abl, Antigens, CD34, Mice, SCID, Mice, 0302 clinical medicine, Mice, Inbred NOD, Cells, Cultured, 0303 health sciences, Reverse Transcriptase Polymerase Chain Reaction, Cell Cycle, Hematopoietic stem cell, Cell Differentiation, Hematology, Fetal Blood, HOX genes, Cell biology, Endothelial stem cell, Haematopoiesis, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cord blood, Leukemia, Myeloid, Chronic-Phase, Neoplastic Stem Cells, Original Article, long-term culture-initiating cells, Stem cell, Adult stem cell, Blotting, Western, Transplantation, Heterologous, Biology, Real-Time Polymerase Chain Reaction, Colony-Forming Units Assay, 03 medical and health sciences, chronic myeloid leukemia, Cancer stem cell, medicine, Animals, Humans, RNA, Messenger, Cell Proliferation, 030304 developmental biology, Homeodomain Proteins, Receptors, Interleukin-2, Hematopoietic Stem Cells, Molecular biology, Nuclear Pore Complex Proteins, Homeobox A10 Proteins
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8286c37305d72bb13b3cd08a1c0c3bcdTest
https://doi.org/10.1038/leu.2012.196Test