المؤلفون: CoHEART Consortium, Bakkers, Jeroen

المساهمون: Medische Fysiologie, Circulatory Health

مصطلحات موضوعية: Abnormalities, Multiple/genetics, Adult, Cell Cycle Proteins/metabolism, DNA Methylation/genetics, Dermis/pathology, Epigenomics, Fibroblasts/metabolism, Gene Expression Profiling, Gene Ontology, Humans, Potassium Channels/metabolism, Proteome/metabolism, Reproducibility of Results, Signal Transduction, Syndrome, Transforming Growth Factor beta/metabolism, Chronic Intestinal Pseudo-obstruction, TGF-β Signaling, CAID Syndrome (Chronic Atrial and Intestinal Dysrhythmia), Epigenetics, TGF-beta Signaling, Gastroenterology, Hepatology, Research Support, Non-U.S. Gov't, Journal Article

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/439279Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/439279Test

المؤلفون: Jessica Piché, Natacha Gosset, Lisa-Marie Legault, Alain Pacis, Andrea Oneglia, Maxime Caron, Philippe Chetaille, Luis Barreiro, Donghai Liu, Xioyan Qi, Stanley Nattel, Séverine Leclerc, Mélanie Breton-Larrivée, Serge McGraw, Gregor Andelfinger, Jeroen Bakkers, Bart Loeys, Michel Pucéat

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Marseille medical genetics - Centre de génétique médicale de Marseille (MMG), Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), CoHEART Consortium

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 2, Pp 411-431 (2019)
Cellular and Molecular Gastroenterology and Hepatology
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 7(2), 411-431
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2019, 7 (2), pp.411-431. ⟨10.1016/j.jcmgh.2018.10.011⟩
CMGH Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Epigenomics, Potassium Channels, IK1, inward rectifying potassium current, Proteome, SILAC, stable isotope labeling by amino acids in cell culture, Bisulfite sequencing, Medizin, Cell Cycle Proteins, ERK, extracellular signal–regulated kinase, Transcriptome, 0302 clinical medicine, PCR, polymerase chain reaction, Transforming Growth Factor beta, p, passage number, Original Research, TGF-β Signaling, TPM, tropomyosin, Gastroenterology, Dermis, Syndrome, Phenotype, CAID, chronic atrial and intestinal dysrhythmia, mRNA, messenger RNA, 3. Good health, Chromatin, Cell biology, DNA methylation, DAB, 3,3′-diaminobenzidine tetra hydrochloride, 030211 gastroenterology & hepatology, Epigenetics, RMP, resting membrane potential, Signal Transduction, Adult, FDR, false discovery rate, JNK, c-Jun-N-terminal kinase, RRBS, reduced representative bisulfite sequencing, Biology, TGF-beta Signaling, 03 medical and health sciences, TGF-β, transforming growth factor-β, Cardiac conduction, Chronic Intestinal Pseudo-obstruction, GO, Gene Ontology, Humans, Abnormalities, Multiple, CIPO, chronic intestinal pseudo-obstruction, lcsh:RC799-869, [SDV.GEN]Life Sciences [q-bio]/Genetics, Hepatology, Gene Expression Profiling, Reproducibility of Results, DNA Methylation, Fibroblasts, CAID Syndrome (Chronic Atrial and Intestinal Dysrhythmia), TAGLN, Transgelin, ATAC, assay for transposase-accessible chromatin with high throughput, 030104 developmental biology, Gene Ontology, lcsh:Diseases of the digestive system. Gastroenterology, Human medicine, MAPK, mitogen-activated protein kinase

وصف الملف: pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86c6072048d78e405868a6d89bbe835Test
http://www.sciencedirect.com/science/article/pii/S2352345X18301577Test

المؤلفون: Sujit Mukherjee, Evangelos Triantafyllou, Oltin T Pop, Fabien Zoulim, Enes Tunc, Alberto Quaglia, Arjuna Singanayagam, Wafa Khamri, Mark Thursz, Tie Zheng Hou, Fanny Lebossé, Julia Wendon, Rooshi Nathwani, Charalambos G. Antoniades, Cathrin Gudd, Naveenta Kumar, A. Dhar

المساهمون: Imperial College London, King‘s College London, Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University College of London [London] (UCL), Manship, Brigitte, BRC ITMAT Funding Scheme, Medical Research Council

المصدر: EBioMedicine
EBioMedicine, 2019, 49, pp.258-268. ⟨10.1016/j.ebiom.2019.10.011⟩

مصطلحات موضوعية: CHRONIC LIVER-FAILURE, 0301 basic medicine, Liver Cirrhosis, Male, Cirrhosis, Research paper, Transcription, Genetic, Apoptosis, Research & Experimental Medicine, CD8-Positive T-Lymphocytes, Chronic liver disease, Severity of Illness Index, 0302 clinical medicine, INFECTION, Ascites, Cytotoxic T cell, Myeloid Cells, CD8(+)T cells, ALD, alcohol-related liver disease, NEUTROPHILS, CD8(+) T cells, medicine.diagnostic_test, ACLF, acute-on-chronic-liver disease, General Medicine, Middle Aged, 3. Good health, CD8+T cells, Phenotype, Treatment Outcome, Medicine, Research & Experimental, 030220 oncology & carcinogenesis, SURVIVAL, CLD, Chronic liver disease, Female, Disease Susceptibility, medicine.symptom, Peritoneum, Life Sciences & Biomedicine, EXPRESSION, CAID, cirrhosis-associated immune dysfunction, NASH, non-alcoholic steatohepatitis, Cirrhosis-associated immune dysfunction, [SDV.CAN]Life Sciences [q-bio]/Cancer, AAH, acute alcoholic hepatitis, Peripheral blood mononuclear cell, General Biochemistry, Genetics and Molecular Biology, Flow cytometry, 03 medical and health sciences, Medicine, General & Internal, Immune system, [SDV.CAN] Life Sciences [q-bio]/Cancer, General & Internal Medicine, medicine, HV, Healthy volunteers, Humans, Aged, Cell Proliferation, Inflammation, Science & Technology, business.industry, ELD, End-stage-liver diseases, HLA-DR Antigens, medicine.disease, AD, acute decompensation, 030104 developmental biology, Immunology, Natural Killer T-Cells, business, CD8, Biomarkers, PMNs, polymorphonuclear neutrophils

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9318081e284f95b31ce34f205764d8dbTest
http://europepmc.org/articles/PMC6945243Test

المؤلفون: Alastair O'Brien, Natalia Becares, Kate Bennet, Simon S. Skene, Jesmond Dalli, Louise China, Romain A. Colas, Zainib Shabir, Suvi Härmälä, Alexander A. Maini

المصدر: Clinical Gastroenterology and Hepatology

مصطلحات موضوعية: Liver Cirrhosis, Cirrhosis, TNF, MDM, Gastroenterology, 0302 clinical medicine, Model for End-Stage Liver Disease, RCT, randomized controlled trial, Immune Response, LM, lipid mediator, TNF, tumor necrosis factor, biology, LBP, lipopolysaccharide-binding protein, Death, SPMs, specialized pro-resolving mediators, 030220 oncology & carcinogenesis, CRP, C-reactive protein, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, medicine.symptom, IV, intravenous, PBMC, peripheral blood mononuclear cell, medicine.medical_specialty, CAID, cirrhosis-associated immune dysfunction, Inflammation, Article, MELD, Model for End-Stage Liver Disease, End Stage Liver Disease, 03 medical and health sciences, Tumor necrosis factor production, Internal medicine, PGE2, prostaglandin E2, medicine, Humans, Immunologic Factors, Decompensation, ATTIRE, Albumin to Prevent Infection in Chronic Liver Failure, DPA, docosapentaenoic acid, Hepatology, Tumor Necrosis Factor-alpha, business.industry, Macrophages, C-reactive protein, Albumin, medicine.disease, AD, acute decompensation, HAS, human albumin solution, IL, interleukin, ACLF, acute-on-chronic liver failure, WCC, white cell count, biology.protein, MDM, monocyte-derived macrophage, business

وصف الملف: text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df3694106ecb00d02676a07a7cc2030Test
https://doi.org/10.1016/j.cgh.2019.08.036Test