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1
المؤلفون: Tobias V Lanz, R Camille Brewer, Peggy P Ho, Kevin M Jude, Daniel Fernandez, Jae-Seung Moon, Ricardo A Fernandes, Alejandro M Gomez, Gabriel-Stefan Nadj, Christopher M Bartley, Ryan D Schubert, Isobel A Hawes, Sara E Vazquez, Manasi Iyer, J Bradley Zuchero, Bianca Teegen, Jeffrey E Dunn, Christopher B Lock, Lucas B Kipp, Victoria C Cotham, Beatrix M Ueberheide, Blake T Aftab, Mark S Anderson, Joseph L DeRisi, Michael R Wilson, Rachael JM Bashford-Rogers, Michael Platten, K Christopher Garcia, Lawrence Steinman, William H Robinson
المصدر: Nature
Nature, vol 603, iss 7900مصطلحات موضوعية: Epstein-Barr Virus Infections, Herpesvirus 4, Human, Multiple Sclerosis, General Science & Technology, Nerve Tissue Proteins, Neurodegenerative, Autoimmune Disease, Article, Mice, Clinical Research, Genetics, 2.1 Biological and endogenous factors, Animals, Humans, Aetiology, Neuron-Glia, B-Lymphocytes, Multidisciplinary, Cell Adhesion Molecules, Neuron-Glia, Herpesvirus 4, Neurosciences, Brain Disorders, Infectious Diseases, Epstein-Barr Virus Nuclear Antigens, Neurological, Cell Adhesion Molecules, Human, Biotechnology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2318b2d41a42f0170e92995f810de60Test
https://doi.org/10.1038/s41586-022-04432-7Test -
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المؤلفون: Daniel W. Sherbenou, Thomas G. Martin, Olivia Perez De Acha, Byron Hann, Blake T. Aftab, Megan Murnane, Yang Su, Jeffery L. Wolf, Shelby C. Bearrows, Bin Liu, Christopher R. Behrens
المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 26, iss 22
Clin Cancer Resمصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Immunoconjugates, medicine.medical_treatment, Mice, 0302 clinical medicine, hemic and lymphatic diseases, Monoclonal, Multiple myeloma, Cancer, Tumor, Antibodies, Monoclonal, Hematology, Middle Aged, Intercellular Adhesion Molecule-1, Flow Cytometry, Antibodies, Anti-Idiotypic, Anti-Idiotypic, medicine.anatomical_structure, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Heterografts, Female, Development of treatments and therapeutic interventions, Multiple Myeloma, Biotechnology, Adult, Antibody-drug conjugate, medicine.drug_class, Oncology and Carcinogenesis, Monoclonal antibody, Article, Antibodies, Cell Line, 03 medical and health sciences, Rare Diseases, Clinical Research, In vivo, Cell Line, Tumor, medicine, Animals, Humans, Oncology & Carcinogenesis, Cell Proliferation, Aged, business.industry, Daratumumab, Immunotherapy, medicine.disease, ADP-ribosyl Cyclase 1, Orphan Drug, 030104 developmental biology, Cancer research, Bone marrow, business, Ex vivo
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c90915ca7c606383916fa2bf8e189cbTest
https://doi.org/10.1158/1078-0432.ccr-20-0400Test -
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المؤلفون: Manher A. Joshi, Michael P. Pender, Lawrence Steinman, Blake T. Aftab, Tap Maniar, Rajiv Khanna, Gavin Giovannoni, Hans-Peter Hartung, Ed Croze, Amit Bar-Or
المصدر: Trends in Molecular Medicine
مصطلحات موضوعية: 0301 basic medicine, Epstein-Barr Virus Infections, Herpesvirus 4, Human, Disease, medicine.disease_cause, multiple sclerosis, Insert (molecular biology), Virus, Article, Epstein–Barr virus, 03 medical and health sciences, Text mining, 0302 clinical medicine, Immune system, ocrelizumab, Animals, Humans, Medicine, Molecular Biology, cell-based therapies, immune evasion, T-cell apoptosis, B-Lymphocytes, Microglia, biology, business.industry, Multiple sclerosis, Correction, medicine.disease, vaccination, Molecular medicine, Vaccination, medicine.anatomical_structure, 030104 developmental biology, Immunology, Cancer research, biology.protein, Molecular Medicine, Ocrelizumab, Immunotherapy, Antibody, business, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e5b0d38d9681dd831b9b7c7cb19fb0Test
http://europepmc.org/articles/PMC7106557Test -
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المؤلفون: Amani Makkouk, Xue (Cher) Yang, Taylor Barca, Anthony Lucas, Mustafa Turkoz, Jonathan T S Wong, Kevin P Nishimoto, Mary M Brodey, Maryam Tabrizizad, Smitha R Y Gundurao, Lu Bai, Arun Bhat, Zili An, Stewart Abbot, Daulet Satpayev, Blake T Aftab, Marissa Herrman
المصدر: Journal for Immunotherapy of Cancer
مصطلحات موضوعية: Cancer Research, Carcinoma, Hepatocellular, T-Lymphocytes, Immunology, Apoptosis, Mice, SCID, cell engineering, adoptive, Immunotherapy, Adoptive, Mice, Glypicans, Mice, Inbred NOD, innate, Tumor Cells, Cultured, tumor microenvironment, Animals, Humans, Immunology and Allergy, Cell Proliferation, Interleukin-15, Pharmacology, Receptors, Chimeric Antigen, Immune Cell Therapies and Immune Cell Engineering, Liver Neoplasms, Receptors, Antigen, T-Cell, gamma-delta, immunity, Xenograft Model Antitumor Assays, Oncology, Leukocytes, Mononuclear, Molecular Medicine, Female, immunotherapy
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e955ee28a80f5478bb3fb0c7d714e4Test
https://doi.org/10.1136/jitc-2021-003441Test -
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المؤلفون: Corey Smith, Sriganesh Srihari, Kunal H. Bhatt, Howard Liu, Sandro V. Porceddu, Liz Kenny, Michelle A Neller, Lea Lekieffre, Pauline Crooks, Rajiv Khanna, Blake T. Aftab
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, Tumor Immunology, Oncology, medicine.medical_specialty, Multivariate analysis, T-Lymphocytes, T cell, Immunology, CD8-Positive T-Lymphocytes, T cell response, Article, Antigen, Antigens, Neoplasm, Internal medicine, medicine, T cell immunity, Humans, Immunology and Allergy, Human papillomavirus 16, business.industry, Papillomavirus Infections, Case-control study, virus diseases, Middle Aged, Oropharyngeal Neoplasms, stomatognathic diseases, medicine.anatomical_structure, Case-Control Studies, Cohort, Female, business, CD8
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82501539933316147072e66ea2150c66Test
https://doi.org/10.1084/jem.20200389Test -
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المؤلفون: Nanette L. Douglas, Rajiv Khanna, Leone Beagley, Pauline Crooks, Zara A. Ioannides, Corey Smith, Michelle A Neller, Kate Thompson, Stefan Blum, Blake T. Aftab, Andrew Swayne, Alan Coulthard, Michael P. Pender, Sweera Rehan, Scott R. Burrows, Kaye D. Hooper, Kerryn A. Green, Tracey Hopkins, Katherine K. Matthews, Peter A. Csurhes
المصدر: JCI Insight, Vol 5, Iss 20 (2020)
JCI Insightمصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Herpesvirus 4, Human, medicine.medical_specialty, Multiple Sclerosis, T-Lymphocytes, T cell, medicine.disease_cause, Immunotherapy, Adoptive, Viral Matrix Proteins, 03 medical and health sciences, 0302 clinical medicine, Antigen, Internal medicine, hemic and lymphatic diseases, medicine, Humans, Cytotoxic T cell, Adverse effect, Aged, business.industry, Multiple sclerosis, General Medicine, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Epstein–Barr virus, Clinical trial, Treatment Outcome, 030104 developmental biology, medicine.anatomical_structure, Epstein-Barr Virus Nuclear Antigens, Medicine, Female, Corrigendum, business, 030217 neurology & neurosurgery, CD8, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc611c8ac688e08c63e0506651eefebTest
https://europepmc.org/articles/PMC6302936Test/ -
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المؤلفون: Hui Liu, Yu Hsiu T. Lin, Megan Murnane, Geoffrey A. Smith, Christine Lam, Margarette C. Mariano, Arun P. Wiita, Jack Taunton, Sandy W. Wong, Jun O. Liu, Constantine S. Mitsiades, Blake T. Aftab, Ian Ferguson, Byron Hann
المصدر: Haematologica, vol 103, iss 7
Haematologicaمصطلحات موضوعية: 0301 basic medicine, Proteomics, Ruxolitinib, Proteome, Cell Communication, Cardiorespiratory Medicine and Haematology, Plasma Cell Disorders, chemistry.chemical_compound, Mice, Piperidines, Bone Marrow, Tumor Microenvironment, 2.1 Biological and endogenous factors, Medicine, Aetiology, Cancer, Hematology, 3. Good health, STAT Transcription Factors, medicine.anatomical_structure, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Multiple Myeloma, medicine.drug, Signal Transduction, Stromal cell, Plasma Cells, Immunology, Article, 03 medical and health sciences, Rare Diseases, In vivo, Animals, Humans, Pyrroles, Protein Kinase Inhibitors, Janus Kinases, Tumor microenvironment, Tofacitinib, 5.2 Cellular and gene therapies, business.industry, Venetoclax, Animal, Mesenchymal stem cell, Drug Repositioning, Mesenchymal Stem Cells, Phosphoproteins, Xenograft Model Antitumor Assays, Disease Models, Animal, Orphan Drug, 030104 developmental biology, Pyrimidines, chemistry, Disease Models, Cancer research, Bone marrow, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3bb91b64a9c4e0fbaed43ab5969e84Test
https://escholarship.org/uc/item/99g7601fTest -
8Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer
المؤلفون: Jennifer N. Rauch, Bryan M. Dunyak, Byron Hann, Peter Walter, Martin Kampmann, Megan Murnane, Min Cho, Xiaokai Li, Teresa A. Colvin, Jason E. Gestwicki, Diego Acosta-Alvear, Blake T. Aftab, Jonathan S. Weissman, Michael Y. Sherman
المصدر: Molecular cancer therapeutics, vol 14, iss 3
مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Cancer Research, Oncology and Carcinogenesis, Allosteric regulation, Antineoplastic Agents, Pharmacology, BAG3, Article, Cell Line, Protein–protein interaction, Mice, Cell Line, Tumor, Proliferating Cell Nuclear Antigen, 2.1 Biological and endogenous factors, Animals, Humans, HSP70 Heat-Shock Proteins, Protein Interaction Domains and Motifs, Oncology & Carcinogenesis, Aetiology, Cancer, Adaptor Proteins, Signal Transducing, Cell Proliferation, Regulation of gene expression, Neoplastic, Tumor, biology, Effector, Forkhead Box Protein M1, Signal Transducing, Adaptor Proteins, Signal transducing adaptor protein, Forkhead Transcription Factors, Pharmacology and Pharmaceutical Sciences, Gene Expression Regulation, Neoplastic, Gene Expression Regulation, Oncology, Hela Cells, Chaperone (protein), MCF-7 Cells, Cancer research, biology.protein, FOXM1, Apoptosis Regulatory Proteins, HT29 Cells, HeLa Cells
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3b22505bee1d46a3729d48f13aa063Test
https://doi.org/10.1158/1535-7163.mct-14-0650Test -
9The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma
المؤلفون: P. Leif Bergsagel, Marta Chesi, Marianne Kraus, Christoph Driessen, Laura K. Shawver, Grace J. Lee, Blake T. Aftab, Szerenke Kiss von Soly, Mark Rolfe, Megan Murnane, Ronan Le Moigne, Jinhai Wang, Daniel Anderson, Jeffrey L. Wolf, Arun P. Wiita, Mary Kamala Menon, Emily M. King, Stevan Djakovic, David J. Wustrow, Ferdie Soriano, Constantine S. Mitsiades, Han Jie Zhou, Eduardo Valle, Stephen T. C. Wong, Thomas G. Martin, Zhi Yong Wu, Eugen Dhimolea, Christine Lam, F. Michael Yakes, Julie Rice, Bing Yao
المصدر: Molecular cancer therapeutics. 16(11)
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Proteasome Endopeptidase Complex, Indoles, Apoptosis, Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Ubiquitin, P97 Inhibitor CB-5083, medicine, Animals, Humans, Nuclear protein, Multiple myeloma, Cell Proliferation, Adenosine Triphosphatases, Cell growth, Nuclear Respiratory Factor 1, Nuclear Proteins, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Pyrimidines, Oncology, Proteasome, 030220 oncology & carcinogenesis, Unfolded protein response, Cancer research, biology.protein, Proteasome inhibitor, Unfolded Protein Response, Multiple Myeloma, Proteasome Inhibitors, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdabd665906a2c466a4f478c5ace23bbTest
https://pubmed.ncbi.nlm.nih.gov/28878026Test -
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المؤلفون: Peter Walter, Xiaobo Wu, Daniel W. Sherbenou, Bin Liu, Blake T. Aftab, Diego Acosta-Alvear, Thomas G. Martin, Aaron C Logan, Yang Su, Byron Hann, Marc A. Shuman, John P. Atkinson, Jeffrey L. Wolf, Arun P. Wiita, Christopher R. Behrens
المصدر: The Journal of clinical investigation, vol 126, iss 12
مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, Antibodies, Neoplasm, viruses, Cell, Gene Dosage, Medical and Health Sciences, Mice, Monoclonal, Multiple myeloma, Cancer, Tumor, biology, Antibodies, Monoclonal, General Medicine, Hematology, female genital diseases and pregnancy complications, 3. Good health, medicine.anatomical_structure, 5.1 Pharmaceuticals, Chromosomes, Human, Pair 1, Pair 1, Antibody, Development of treatments and therapeutic interventions, Multiple Myeloma, Human, Biotechnology, Research Article, Antibody-drug conjugate, medicine.drug_class, Immunology, Monoclonal antibody, Chromosomes, Antibodies, Cell Line, Membrane Cofactor Protein, 03 medical and health sciences, Rare Diseases, Clinical Research, Cell Line, Tumor, medicine, Genetics, Animals, Humans, Innate immune system, business.industry, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Cell culture, biology.protein, Cancer research, Neoplasm, Bone marrow, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4493ea8c812dbe33beb060ad3da7b1b3Test
https://europepmc.org/articles/PMC5127683Test/