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1
المؤلفون: Agnieszka Lewandowska, Corinne P. Soutar, Alexander I. Greenwood, Evgeny Nimerovsky, Ashley M. De Lio, Jordan T. Holler, Grant S. Hisao, Anuj Khandelwal, Jiabao Zhang, Anna M. SantaMaria, Charles D. Schwieters, Taras V. Pogorelov, Martin D. Burke, Chad M. Rienstra
المصدر: Nat Struct Mol Biol
مصطلحات موضوعية: Antifungal Agents, Cell Membrane, Molecular Conformation, Molecular Dynamics Simulation, Streptomyces, Article, Immunocompromised Host, Structural Biology, Amphotericin B, Ergosterol, Humans, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, Cells, Cultured, Invasive Fungal Infections
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d1354f9972e7ba8e6e7c9d0c9a5c48Test
https://doi.org/10.1038/s41594-021-00685-4Test -
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المؤلفون: Jocelyn Trottier, Fereshteh Fani, Martin D. Burke, Philippe Leprohon, Hélène Gingras, Anuj Khandelwal, Angana Mukherjee, Marc Ouellette, Jiabao Zhang, Christelle Morelle, Olivier Barbier
المصدر: ACS infectious diseases. 7(8)
مصطلحات موضوعية: Drug, animal diseases, media_common.quotation_subject, Drug Compounding, Leishmania donovani, Antiprotozoal Agents, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Amphotericin B, parasitic diseases, Medicine, Humans, 030304 developmental biology, media_common, 0303 health sciences, Ergosterol, biology, urogenital system, 030306 microbiology, business.industry, technology, industry, and agriculture, bacterial infections and mycoses, Leishmania, biology.organism_classification, medicine.disease, 3. Good health, Infectious Diseases, Visceral leishmaniasis, chemistry, Toxicity, Leishmaniasis, Visceral, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048705ab5f9c5baf01de5ab5bc3639c5Test
https://pubmed.ncbi.nlm.nih.gov/34282886Test -
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المؤلفون: Chitra Subramanian, Robert L. Matts, Brian S. J. Blagg, Anuj Khandelwal, Weiya Liu, Jeffery M. Holzbeierlein, Junpeng Deng, Mark S. Cohen, Victor W. Day, Sanket J. Mishra, Caitlin N. Kent, Maurie Balch, Shuxia Peng
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Gene isoform, Science, Drug Evaluation, Preclinical, General Physics and Astronomy, Antineoplastic Agents, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, 03 medical and health sciences, Cell Line, Tumor, Heat shock protein, polycyclic compounds, medicine, Humans, Protein Isoforms, Structure–activity relationship, HSP90 Heat-Shock Proteins, Heat shock, lcsh:Science, Multidisciplinary, biology, Chemistry, HEK 293 cells, Cancer, Hydrogen Bonding, General Chemistry, medicine.disease, Hsp90, 3. Good health, Cell biology, HEK293 Cells, 030104 developmental biology, Drug Design, biology.protein, Protein folding, lcsh:Q
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca0d3fd460c06cb7b268c988c06edc1Test
http://link.springer.com/article/10.1038/s41467-017-02013-1Test -
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المؤلفون: Vincent M. Crowley, Anuj Khandelwal, Sanket J. Mishra, Brian S. J. Blagg, Jessica Ann Hall, Jinbo Zhao, Aaron Muth
المصدر: Bioorganic & Medicinal Chemistry. 22:4083-4098
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Cell, Pharmaceutical Science, Fluorescence Polarization, Plasma protein binding, Benzoates, Biochemistry, Article, Structure-Activity Relationship, Isomerism, Cell Movement, Cell Line, Tumor, Drug Discovery, medicine, Humans, Structure–activity relationship, Moiety, HSP70 Heat-Shock Proteins, Molecular Biology, Cell Proliferation, biology, Cell growth, Chemistry, Organic Chemistry, Membrane Proteins, Hsp90, Quinone, Kinetics, medicine.anatomical_structure, Cell culture, biology.protein, Molecular Medicine, Acetanilides, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766a6a73aaae90e4cbce3f9819c48ddcTest
https://doi.org/10.1016/j.bmc.2014.05.075Test -
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المؤلفون: Raquel L. Lieberman, Aaron Muth, Dustin J. E. Huard, Andrew R. Stothert, Vincent M. Crowley, Sanket J. Mishra, Adam S. Duerfeldt, Brian S. J. Blagg, Anuj Khandelwal, Jinbo Zhao, James Lewis Kizziah, Chad A. Dickey
المصدر: Journal of medicinal chemistry. 59(7)
مصطلحات موضوعية: 0301 basic medicine, Glucose-regulated protein, Integrin, Blotting, Western, Antineoplastic Agents, Breast Neoplasms, Crystallography, X-Ray, Benzoates, Article, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Cell Movement, Heat shock protein, Drug Discovery, Hydroxybenzoates, Humans, Receptor, Eye Proteins, Myocilin, Cell Proliferation, Glycoproteins, Wound Healing, Binding Sites, Membrane Glycoproteins, biology, Chemistry, Endoplasmic reticulum, Imidazoles, Glaucoma, Hsp90, Cell biology, Cytoskeletal Proteins, 030104 developmental biology, Biochemistry, 030220 oncology & carcinogenesis, Proteolysis, biology.protein, Molecular Medicine, Acetanilides, Female, Bioisostere, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9ebeee6fd1cca960707b701c9fbc34Test
https://pubmed.ncbi.nlm.nih.gov/27003516Test -
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المؤلفون: Anuj, Khandelwal, Vincent M, Crowley, Brian S J, Blagg
المصدر: Medicinal research reviews. 36(1)
مصطلحات موضوعية: Biological Products, Lactams, Macrocyclic, Antineoplastic Agents, Article, Protein Structure, Tertiary, Molecular Docking Simulation, Inhibitory Concentration 50, Purines, Drug Design, Neoplasms, Drug Discovery, Benzoquinones, Animals, Humans, HSP90 Heat-Shock Proteins, Macrolides, Enzyme Inhibitors, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::3ca189acc52e8259c77d61be8c383e08Test
https://pubmed.ncbi.nlm.nih.gov/26010985Test -
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المؤلفون: Jeffery M. Holzbeierlein, Bhaskar Reddy Kusuma, Wen Gu, George A. Vielhauer, Douglas Brown, Brian S. J. Blagg, Weiya Liu, Anuj Khandelwal
المصدر: Bioorganicmedicinal chemistry. 22(4)
مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Plasma protein binding, Naphthalenes, Biochemistry, Article, chemistry.chemical_compound, Coumarins, Cell Line, Tumor, Drug Discovery, medicine, Humans, HSP90 Heat-Shock Proteins, Molecular Biology, Novobiocin, Biological evaluation, Cell Proliferation, biology, Chemistry, Cell growth, Organic Chemistry, Quinoline, Coumarin, Hsp90, Cell culture, biology.protein, MCF-7 Cells, Quinolines, Molecular Medicine, medicine.drug, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694ba210e42ce912d4815293dc259ce1Test
https://pubmed.ncbi.nlm.nih.gov/24461493Test -
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المؤلفون: Brian S. J. Blagg, Jessica Ann Hall, Anuj Khandelwal
المصدر: The Journal of organic chemistry. 78(16)
مصطلحات موضوعية: Stereochemistry, Antineoplastic Agents, complex mixtures, Catechin, Article, Hsp90 inhibitor, chemistry.chemical_compound, Structure-Activity Relationship, Western blot, medicine, Structure–activity relationship, Humans, HSP90 Heat-Shock Proteins, Natural product, biology, medicine.diagnostic_test, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, food and beverages, Hsp90, chemistry, Biochemistry, Polyphenol, biology.protein, MCF-7 Cells, Drug Screening Assays, Antitumor, Linker
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6150409f2bc1467fda9fb578770c4dTest
https://pubmed.ncbi.nlm.nih.gov/23834230Test