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المؤلفون: Darby Ball, Sheena D'Arcy, Paul Brear, Marko Hyvönen, Katherine Stott
المساهمون: D'Arcy, Sheena [0000-0001-5055-988X], Hyvönen, Marko [0000-0001-8683-4070], Apollo - University of Cambridge Repository
المصدر: J Med Chem
مصطلحات موضوعية: Stereochemistry, Allosteric regulation, Plasma protein binding, Molecular Dynamics Simulation, Crystallography, X-Ray, Ligands, Binding, Competitive, 01 natural sciences, Article, 03 medical and health sciences, chemistry.chemical_compound, Adenosine Triphosphate, Allosteric Regulation, Drug Discovery, medicine, Humans, Naphthyridines, Binding site, Protein kinase A, Casein Kinase II, Nuclear Magnetic Resonance, Biomolecular, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, Chemistry, Kinase, Deuterium Exchange Measurement, Isothermal titration calorimetry, Small molecule, Adenosine, Recombinant Proteins, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Biochemistry, Original report, Phenazines, Molecular Medicine, Casein kinase 2, Adenosine triphosphate, Allosteric Site, Protein Binding, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb451b7c96794b58d85fbd55b07711aTest
https://doi.org/10.1021/acs.jmedchem.0c01173Test -
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المؤلفون: Michael A. Kennedy, Shenyuan Xu
المصدر: Proteins: Structure, Function, and Bioinformatics. 88:1493-1512
مصطلحات موضوعية: Protein Conformation, alpha-Helical, Repetitive Sequences, Amino Acid, Protein Folding, Stereochemistry, Arabidopsis, Molecular Dynamics Simulation, Cyanobacteria, Biochemistry, Pentapeptide repeat, 03 medical and health sciences, Molecular dynamics, chemistry.chemical_compound, Bacterial Proteins, Structural Biology, Group (periodic table), Amide, Animals, Humans, Order (group theory), Protein Interaction Domains and Motifs, Molecular Biology, 030304 developmental biology, 0303 health sciences, Binding Sites, Protein Stability, Hydrogen bond, Protein dynamics, 030302 biochemistry & molecular biology, Deuterium Exchange Measurement, Hydrogen Bonding, chemistry, Thermodynamics, Protein Conformation, beta-Strand, Hydrogen–deuterium exchange, Oligopeptides, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabaf4092fd5f011755d260c78dd3fe9Test
https://doi.org/10.1002/prot.25969Test -
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المؤلفون: Ke Sherry Li, Brett R. Beno, Ekaterina G. Deyanova, Richard Y.-C. Huang, Michael L. Gross, Elizabeth T. Schaper Bergman, Guodong Chen
المصدر: J Am Soc Mass Spectrom
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, DNA footprinting, Cell Cycle Proteins, 010402 general chemistry, 01 natural sciences, Article, Benzodiazepines, chemistry.chemical_compound, Protein structure, Tandem Mass Spectrometry, Structural Biology, Humans, Spectroscopy, Hydroxyl Radical, Protein footprinting, Chemistry, 010401 analytical chemistry, Deuterium Exchange Measurement, Small molecule, Footprinting, 0104 chemical sciences, Hydrogen–deuterium exchange, Hydroxyl radical, Small molecule binding, Hydrophobic and Hydrophilic Interactions, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa943384c2dea101058a6750980ae2cTest
https://doi.org/10.1007/s13361-019-02316-1Test -
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المؤلفون: Anthony T. Iavarone, Theodore R. Holman, Adam R. Offenbacher, Wilian A. Cortopassi, Chris Whittington, Wan-Chen Tsai, Ansari Mukhtar Aleem, Chakrapani Kalyanaraman, Ewa Skrzypczak-Jankun, Angel Baroz, Matthew P. Jacobson
المصدر: Biochemistry. 60(10)
مصطلحات موضوعية: Models, Molecular, biology, Stereochemistry, Protein Conformation, Dimer, Active site, Deuterium Exchange Measurement, Arachidonate 12-Lipoxygenase, Biochemistry, Hydrophobic effect, Molecular Docking Simulation, chemistry.chemical_compound, Monomer, Protein structure, chemistry, Docking (molecular), Mutagenesis, Catalytic Domain, Helix, Mutation, biology.protein, Humans, Hydrogen–deuterium exchange, Protein Multimerization
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af46aef9ceae95de67e8a37d8fabfb10Test
https://pubmed.ncbi.nlm.nih.gov/33635645Test -
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المؤلفون: Lily Kiaei, Changiz Eslahchi, Atousa Aliahmadi, Ahmad Shahir Sadr, Alireza Ghassempour, Mahmoud Kiaei, Mina Nekouei, Zahra Abdollahpour
المصدر: Metabolic brain disease. 37(1)
مصطلحات موضوعية: chemistry.chemical_classification, Molecular mass, Chemistry, Stereochemistry, Mutant, Amyotrophic Lateral Sclerosis, Computational Biology, Deuterium Exchange Measurement, Deuterium, Biochemistry, Amino acid, Molecular Docking Simulation, Cellular and Molecular Neuroscience, Matrix-assisted laser desorption/ionization, Profilins, Epitope mapping, Docking (molecular), Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Glycine, Humans, Hydrogen–deuterium exchange, Neurology (clinical)
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0608d05156d3ce3fe92b4a74f0d48f5Test
https://pubmed.ncbi.nlm.nih.gov/34302583Test -
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المؤلفون: Adam L. Yokom, Xiaoshan Shi, Lindsey N. Young, Richard J. Youle, James H. Hurley, Chunxin Wang
المصدر: The Journal of cell biology, vol 219, iss 7
The Journal of Cell Biologyمصطلحات موضوعية: Dimer, Vesicular Transport Proteins, Gene Expression, Sequence Homology, Autophagy-Related Proteins, Medical and Health Sciences, chemistry.chemical_compound, 0302 clinical medicine, TANK-binding kinase 1, Structural Biology, Autophagy-Related Protein-1 Homolog, Cloning, Molecular, 0303 health sciences, Kinase, Chemistry, Intracellular Signaling Peptides and Proteins, Biological Sciences, Autophagy-related protein 13, Protein-Serine-Threonine Kinases, Negative stain, Amino Acid, Signal Transduction, Protein Binding, Structural similarity, Stereochemistry, Cell death and autophagy, Recombinant Fusion Proteins, Genetic Vectors, Multiangle light scattering, Biology, Protein Serine-Threonine Kinases, Article, 03 medical and health sciences, Autophagy, Humans, Molecule, Protein Interaction Domains and Motifs, Amino Acid Sequence, 030304 developmental biology, Binding Sites, Sequence Homology, Amino Acid, Cryoelectron Microscopy, Deuterium Exchange Measurement, Molecular, Cell Biology, ULK1, HEK293 Cells, Gene Expression Regulation, Mutation, Biophysics, Sequence Alignment, 030217 neurology & neurosurgery, Cloning, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5bef9db5e9831dfe40dd9e23b81566dTest
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المؤلفون: Matthew K. Thompson, Richard N. Armstrong, Charles R. Sanders, Mary E. Keithly, Kristin Diane Droege
المصدر: Biochemistry
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, PLAT domain, Gene isoform, Leukotrienes, Lipid Peroxides, Protein Conformation, Stereochemistry, Protein domain, Peptide Mapping, Biochemistry, Mass Spectrometry, Article, 03 medical and health sciences, Lipoxygenase, Cytosol, Protein structure, Protein Domains, Catalytic Domain, Arachidonate 15-Lipoxygenase, Humans, Arachidonic Acid, integumentary system, biology, Chemistry, Cell Membrane, Deuterium Exchange Measurement, 030104 developmental biology, Membrane, biology.protein, Calcium, lipids (amino acids, peptides, and proteins), Hydrogen–deuterium exchange
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f251bfb8e123e8b1bdb52be3a81d7b8Test
https://doi.org/10.1021/acs.biochem.7b00559Test -
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المؤلفون: Daniel Deredge, Asaminew H. Aytenfisu, Eric J. Sundberg, Jonathan J. Du, Erik H. Klontz, Alexander D. MacKerell
المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 7, p e1009103 (2021)مصطلحات موضوعية: 0301 basic medicine, Molecular model, Hydrolases, Physiology, Protein Conformation, Biochemistry, 01 natural sciences, Substrate Specificity, Immune Physiology, Biochemical Simulations, Medicine and Health Sciences, Glycoside hydrolase, Biology (General), Crystallography, Immune System Proteins, 010304 chemical physics, Ecology, biology, Chemistry, Simulation and Modeling, Physics, Condensed Matter Physics, Ligand (biochemistry), Enzymes, Computational Theory and Mathematics, Modeling and Simulation, Physical Sciences, Crystal Structure, Carbohydrate-binding module, Antibody, Research Article, Glycan, Glycoside Hydrolases, QH301-705.5, Streptococcus pyogenes, Stereochemistry, Immunology, Protein domain, Molecular Dynamics Simulation, Research and Analysis Methods, Antibodies, Endoglycosidase, Protein–protein interaction, 03 medical and health sciences, Cellular and Molecular Neuroscience, Protein Domains, Bacterial Proteins, Polysaccharides, 0103 physical sciences, Genetics, Solid State Physics, Humans, Protein Interactions, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Biology and Life Sciences, Computational Biology, Proteins, Deuterium Exchange Measurement, Probability Theory, Probability Distribution, Immunoglobulin Fc Fragments, 030104 developmental biology, Docking (molecular), Immunoglobulin G, Enzymology, biology.protein, Biophysics, Mathematics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cd72a91df0bb6568d2639ad1c3fd77Test
https://doi.org/10.1371/journal.pcbi.1009103Test -
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المؤلفون: Kyle Anderson, Ettore Appella, Subrata Debnath, Elyssia S. Gallagher, Jeffrey W. Hudgens, Sharlyn J. Mazur, Stewart R. Durell, Lisa M. Miller Jenkins
المصدر: Biochemistry. 56:2676-2689
مصطلحات موضوعية: inorganic chemicals, 0301 basic medicine, Protein Conformation, Stereochemistry, Inorganic chemistry, Biochemistry, Mass Spectrometry, Article, Serine, 03 medical and health sciences, Protein structure, Humans, Threonine, Binding site, Binding Sites, 030102 biochemistry & molecular biology, biology, Chemistry, Deuterium Exchange Measurement, Active site, Protein Phosphatase 2C, 030104 developmental biology, Deuterium, biology.protein, Hydrogen–deuterium exchange
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6549363acbe5bfe6629cd70aa4385efTest
https://doi.org/10.1021/acs.biochem.6b01220Test -
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المؤلفون: John F. Valliere-Douglass, Lucy Yan Pan, Oscar Salas-Solano
المصدر: mAbs. 9:307-318
مصطلحات موضوعية: 0301 basic medicine, Antibody-drug conjugate, Immunoconjugates, Stereochemistry, Immunology, Peptide, Protein Engineering, 01 natural sciences, Mass Spectrometry, 03 medical and health sciences, Protein structure, Report, Side chain, Animals, Humans, Immunology and Allergy, chemistry.chemical_classification, Chemistry, 010401 analytical chemistry, Antibodies, Monoclonal, Deuterium Exchange Measurement, Footprinting, 0104 chemical sciences, Amino acid, Kinetics, 030104 developmental biology, Covalent bond, Hydrogen–deuterium exchange
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4208d85c9e63e43d946270f9827f0832Test
https://doi.org/10.1080/19420862.2016.1268306Test