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المؤلفون: Mirunalini Ravichandran, Subhiksha Subramanian
المصدر: Fundamental & Clinical Pharmacology. 36:72-80
مصطلحات موضوعية: Pharmacology, Nervous system, Orexins, Drug discovery, Neuropeptides, digestive, oral, and skin physiology, Optogenetics, Biology, Orexin receptor, Receptors, G-Protein-Coupled, medicine.anatomical_structure, nervous system, Orexin Receptors, Sleep Initiation and Maintenance Disorders, mental disorders, medicine, Drug approval, Humans, Pharmacology (medical), Receptor, Neuroscience, hormones, hormone substitutes, and hormone antagonists, G protein-coupled receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3940a00d6a047f0695b9a1c4ed9a95caTest
https://doi.org/10.1111/fcp.12723Test -
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المؤلفون: Giorgio Bergamini, Michel A. Steiner, Catherine Roch, Martine Clozel
المصدر: Psychopharmacology
مصطلحات موضوعية: Pyrrolidines, Insomnia, Daridorexant, Allosteric regulation, Physical dependence, Review, Pharmacology, Doras, Nonclinical, Orexin Receptors, Sleep Initiation and Maintenance Disorders, Dual orexin receptor antagonist, medicine, Humans, Receptor, biology, Mechanism (biology), business.industry, Sleep architecture, Imidazoles, Antagonist, biology.organism_classification, Orexin receptor, Orexin, Orexin Receptor Antagonists, medicine.symptom, Sleep, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98223dcb1d64e58042db5b10ea52358eTest
https://doi.org/10.1007/s00213-021-05954-0Test -
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المؤلفون: Xuewen Gu, Penghua Fang, Yuqing She, Jingjing Sun, Zhenwen Zhang
المصدر: Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity. 27:1415-1425
مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Hypothalamus, Neuropeptide, Galanin, Biology, Mice, Orexin-A, Insulin resistance, Metabolic Diseases, Internal medicine, medicine, Animals, Humans, Obesity, Receptor, digestive, oral, and skin physiology, medicine.disease, Receptor, Galanin, Type 1, Mice, Inbred C57BL, Psychiatry and Mental health, Clinical Psychology, Endocrinology, nervous system, biology.protein, Animal studies, Insulin Resistance, hormones, hormone substitutes, and hormone antagonists, GLUT4
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd229e5122cdada23a38334f4dbac49Test
https://doi.org/10.1007/s40519-021-01280-8Test -
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المؤلفون: Benjamin P. Hurrell, Meng Li, Jacob D. Painter, Pedram Shafiei-Jahani, Yong-Hwee Eddie Loh, Doumet Georges Helou, Omid Akbari, Emily Howard, Lauriane Galle-Treger, Christine Quach
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Science, General Physics and Astronomy, Inflammation, Innate lymphoid cells, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Antigens, CD, Orexin Receptors, Eosinophilia, medicine, Animals, Humans, Lymphocytes, Receptor, Lung, Cell Proliferation, Mice, Inbred BALB C, Multidisciplinary, Membrane Glycoproteins, Effector, business.industry, Interleukins, Innate lymphoid cell, General Chemistry, Pneumonia, respiratory system, Interleukin-33, Immune checkpoint, Asthma, Immunity, Innate, respiratory tract diseases, DNA-Binding Proteins, Disease Models, Animal, 030104 developmental biology, Cytokine, 030220 oncology & carcinogenesis, Humanized mouse, Immunology, Cytokines, Female, Signal transduction, medicine.symptom, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312552aaf8bb384498450cb85b718470Test
https://doaj.org/article/fea260e6f82a47a287a0d596f7eecfe6Test -
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المؤلفون: Junji Furukawa, Chika Higashi, Shunsuke Maehara, Takashi Takeuchi, Takumi Ota, Natsuko Yuge
المصدر: Neuropsychopharmacology Reports
مصطلحات موضوعية: Male, Agonist, medicine.drug_class, Administration, Oral, CHO Cells, Pharmacology, OX1 receptor, Rats, Sprague-Dawley, Cricetulus, Orexin Receptors, In vivo, Cricetinae, medicine, Animals, Humans, Pharmacology (medical), sleep, Receptor, Orexins, Chemistry, Antagonist, Electroencephalography, Original Articles, OX2 receptor, Receptor antagonist, In vitro, Rats, Bioavailability, Orexin, Psychiatry and Mental health, Clinical Psychology, orexin, Original Article, Orexin Receptor Antagonists
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb587ea061a73b9b03f49de9c18959cTest
https://doi.org/10.1002/npr2.12105Test -
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المؤلفون: Kai Yuan, Lin Lu, Ying Han, Yong-Bo Zheng
المصدر: Neurosci Bull
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Neurology, Lateral hypothalamus, Physiology, media_common.quotation_subject, Review, Doras, 03 medical and health sciences, 0302 clinical medicine, Orexin Receptors, mental disorders, medicine, Animals, Humans, Psychiatry, Receptor, media_common, Orexins, biology, business.industry, Mental Disorders, General Neuroscience, Addiction, digestive, oral, and skin physiology, Suvorexant, General Medicine, biology.organism_classification, Orexin, 030104 developmental biology, nervous system, Anxiety, Orexin Receptor Antagonists, medicine.symptom, business, hormones, hormone substitutes, and hormone antagonists, psychological phenomena and processes, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546ae3b1529165042d5cc10cee7639d2Test
https://doi.org/10.1007/s12264-019-00447-9Test -
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المؤلفون: Tingting Mou, Rolf Fronczek, Dick F. Swaab, Kangyu Jin, Jinfeng Duan, Haimei Li, Weijuan Xu, Ai-Min Bao, Jing Lu, Jin-Hui Li, Manli Huang
المساهمون: Netherlands Institute for Neuroscience (NIN)
المصدر: Schizophrenia bulletin, 47, 1310-1319. Oxford University Press
Schizophr Bull
Schizophrenia Bulletin, 47(5), 1310-1319. OXFORD UNIV PRESSمصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Prefrontal Cortex, superior frontal gyrus, Neurotransmission, cerebrospinal fluid, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Sex Factors, Orexin Receptors, Internal medicine, mental disorders, medicine, Humans, hypothalamus, Receptor, orexin, hypocretin receptor, plasma, Orexins, hypocretin receptor, business.industry, Middle Aged, medicine.disease, 030227 psychiatry, Orexin, schizophrenia, Psychiatry and Mental health, Endocrinology, Superior frontal gyrus, orexin, nervous system, Schizophrenia, Hypothalamus, Female, Autopsy, hypocretin, business, 030217 neurology & neurosurgery, psychological phenomena and processes, Hypocretin orexin, Regular Articles
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7365773eafaeccb2f576b7012f99e5ffTest
https://hdl.handle.net/1887/3248773Test -
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المؤلفون: Fabio Arturo Iannotti, Fabiana Piscitelli, Pietro Amodeo, Rosa Maria Vitale, Vincenzo Di Marzo, Ranjev Savopoulos, Luigia Cristino, Aniello Schiano Moriello, Royston A. Gray, Luciano De Petrocellis, Lea Tunisi
المصدر: Biomolecules, Vol 11, Iss 1134, p 1134 (2021)
Biomolecules
Volume 11
Issue 8
Biomolecules 11 (2021). doi:10.3390/biom11081134
info:cnr-pdr/source/autori:Vitale R.M.; Iannotti F.A.; Moriello A.S.; Tunisi L.; Piscitelli F.; Savopoulos R.; Cristino L.; De Petrocellis L.; Amodeo P.; Gray R.; Di Marzo V./titolo:Identification and characterization of cannabidiol as an ox1r antagonist by computational and in vitro functional validation/doi:10.3390%2Fbiom11081134/rivista:Biomolecules/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11مصطلحات موضوعية: Protein Conformation, alpha-Helical, 0301 basic medicine, Gene Expression, Pharmacology, Biochemistry, Radioligand Assay, cannabidiol, 0302 clinical medicine, Transgenes, Receptor, media_common, Chemistry, calcium mobilization assay, Ligand (biochemistry), calcium influx assay, Orexin receptor, QR1-502, Molecular Imaging, Molecular Docking Simulation, calcium imaging, Anticonvulsants, Orexin Receptor Antagonists, Protein Binding, medicine.drug, Drug, orexin receptors, OX1R, media_common.quotation_subject, CHO Cells, Microbiology, Article, 03 medical and health sciences, Cricetulus, medicine, Animals, Humans, Protein Interaction Domains and Motifs, Molecular Biology, Orexins, Binding Sites, Antagonist, antagonist, molecular docking, In vitro, molecular dynamics, Orexin, Kinetics, 030104 developmental biology, Anti-Anxiety Agents, Calcium, Protein Conformation, beta-Strand, Cannabidiol, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774e5847c77075e8bf23ab08f2e5ffadTest
https://www.mdpi.com/2218-273X/11/8/1134Test -
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المساهمون: HUS Medical Imaging Center, Kliinisen neurofysiologian yksikkö, Department of Neurosciences, University of Helsinki, Clinicum, Neurologian yksikkö, HUS Neurocenter, Helsinki University Hospital Area
المصدر: Sleep Medicine. 77:82-87
مصطلحات موضوعية: Narcolepsy type 1, Cataplexy, Hypocretin, 3124 Neurology and psychiatry, Receptors, G-Protein-Coupled, M2 muscarinic receptor autoantibodies, AUTONOMIC CONTROL, 03 medical and health sciences, 0302 clinical medicine, SCHIZOPHRENIA, Muscarinic acetylcholine receptor, medicine, Humans, Receptor, MUSCARINIC RECEPTORS, Autoantibodies, Narcolepsy, Orexins, CARDIOMYOPATHY, HEART-RATE-VARIABILITY, STRIATUM, business.industry, Neuropeptides, Intracellular Signaling Peptides and Proteins, Autoantibody, Muscarinic acetylcholine receptor M2, General Medicine, medicine.disease, SLEEP, 3. Good health, Orexin, Nociception, 030228 respiratory system, Nociception receptor autoantibodies, Immunology, Female, medicine.symptom, CATAPLEXY, business, 030217 neurology & neurosurgery, beta 2 adrenergic receptor autoantibodies
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2726a7dbdfbacf8ff3a0ab6e206b423bTest
https://doi.org/10.1016/j.sleep.2020.11.038Test -
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المؤلفون: Voisin Thierry, Gratio Valérie, Couvineau Alain, Nicole Pascal
المصدر: Molecules
Molecules, Vol 26, Iss 4849, p 4849 (2021)مصطلحات موضوعية: Pharmaceutical Science, Neuropeptide, Organic chemistry, gastroenterology, Review, Models, Biological, Analytical Chemistry, QD241-441, GPCR, Orexin Receptors, Neoplasms, Drug Discovery, mental disorders, medicine, Animals, Humans, cancer, Molecular Targeted Therapy, Physical and Theoretical Chemistry, Receptor, neuropeptide, Orexins, business.industry, digestive, oral, and skin physiology, apoptosis, Cancer, medicine.disease, Orexin, nervous system, Chemistry (miscellaneous), Hypothalamus, Cancer research, Molecular Medicine, Wakefulness, business, Homeostasis, hormones, hormone substitutes, and hormone antagonists, psychological phenomena and processes, Narcolepsy, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bda9839d3834723a59b45c3d80b294Test
https://pubmed.ncbi.nlm.nih.gov/34443437Test