نتائج البحث

1

Emergence of directional bias in tau deposition from axonal transport dynamics

المؤلفون: Pedro D. Maia, Chris Mezias, Parul Verma, Justin Torok, Ashish Raj

المساهمون: Migliore, Michele

المصدر: PLoS Computational Biology, Vol 17, Iss 7, p e1009258 (2021)
PLoS computational biology, vol 17, iss 7
PLoS Computational Biology

مصطلحات موضوعية: 0301 basic medicine, Protein Folding, Aging, Protein Conformation, Kinesins, Neurodegenerative, Alzheimer's Disease, Biochemistry, Axonal Transport, Mathematical Sciences, Mice, Nerve Fibers, Medical Conditions, 0302 clinical medicine, Animal Cells, Models, Medicine and Health Sciences, 2.1 Biological and endogenous factors, Aetiology, Biology (General), Feedback, Physiological, Neurons, Ecology, Chemistry, Dynamics (mechanics), Microtubule Motors, Neurodegenerative Diseases, Animal Models, Biological Sciences, Active Transport, Experimental Organism Systems, Neurology, Computational Theory and Mathematics, Tauopathies, Cell Processes, Modeling and Simulation, Neurological, Kinesin, Tauopathy, Cellular Types, Research Article, Tau pathology, Bioinformatics, QH301-705.5, Physiological, Models, Neurological, Mouse Models, tau Proteins, Research and Analysis Methods, Feedback, Motor protein, 03 medical and health sciences, Cellular and Molecular Neuroscience, Model Organisms, Spatio-Temporal Analysis, Molecular Motors, Alzheimer Disease, Information and Computing Sciences, Mental Health and Psychiatry, Genetics, Acquired Cognitive Impairment, medicine, Animals, Humans, Computer Simulation, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Animal, Neurosciences, Biology and Life Sciences, Proteins, Computational Biology, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Biological Transport, Cell Biology, Dendrites, medicine.disease, Axons, Brain Disorders, Directional bias, Disease Models, Animal, Cytoskeletal Proteins, Metabolism, 030104 developmental biology, Solubility, Cellular Neuroscience, Disease Models, Animal Studies, Axoplasmic transport, Dementia, Neuroscience, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93126b906e577d8f3746de1b766e8ed3Test
https://doaj.org/article/24834eed861e4290ab95264ca3a273d1Test

2

Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B

المؤلفون: Federico Lecumberry, Lucía Alfaya, Camila Davison, Gabriela Casanova, Jose L. Badano, Paola Lepanto, Florencia Irigoín, Rossina Novas, Mauricio Ramos, María Inés Fariello, Magela Rodao, Matías Fabregat, Gualberto González-Sapienza, Magdalena Cardenas-Rodriguez

المساهمون: Novas, Rosina. Instituto Pasteur (Montevideo), Cardenas Rodríguez, Magdalena. Instituto Pasteur (Montevideo), Lepanto, Paola. Instituto Pasteur (Montevideo), Fabregat, Matías. Instituto Pasteur (Montevideo), Rodao, Magela. Universidad de la República (Uruguay). Facultad de Ciencias. Unidad de Microscopía, Fariello, María Inés. Instituto Pasteur (Montevideo), Ramos, Mauricio. Instituto Pasteur (Montevideo), Davison, Camilia. Universidad de la República (Uruguay). Facultad de Ciencias. Unidad de Microscopía, Casanova, Gabriela. Universidad de la República (Uruguay). Facultad de Ciencias. Unidad de Microscopía, Lecumberry, Federico. Instituto Pasteur (Montevideo), Irigoín, Florencia. Instituto Pasteur (Montevideo), Badano, José L. Instituto Pasteur (Montevideo)

المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
COLIBRI
Universidad de la República
instacron:Universidad de la República

مصطلحات موضوعية: 0301 basic medicine, Science, Nuclear Localization Signals, Kinesins, Cell Cycle Proteins, Article, 03 medical and health sciences, 0302 clinical medicine, Bardet–Biedl syndrome, Ciliogenesis, Bardet-Biedl syndrome, medicine, Animals, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, Cilia, Obesity, education, Bardet-Biedl Syndrome, Zebrafish, education.field_of_study, Multidisciplinary, biology, Cilium, Retinal Degeneration, Proteins, Morphant, Zebrafish Proteins, zebrafish, medicine.disease, biology.organism_classification, Cell biology, Cytoskeletal Proteins, Polydactyly, Protein Transport, Ciliopathy, Phenotype, HEK293 Cells, 030104 developmental biology, Kinesin light chain 1, Mutation, Kinesin, Medicine, 030217 neurology & neurosurgery, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7365c2c2cbcc3d61fd3b2f1c9ca93972Test
https://doaj.org/article/b12b6dca1e794eb5831efb3cd8564235Test

3

Lysosome motility and distribution: Relevance in health and disease

المؤلفون: Maria-Isabel Yuseff, Alejandra R. Alvarez, Cristian Valls, Silvana Zanlungo, Catalina De la Fuente, Juan Esteban Oyarzún, Jonathan Lagos, Mary Carmen Vázquez

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:1076-1087

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5881205ca40fe465185afcd150880fe1Test
https://doi.org/10.1016/j.bbadis.2019.03.009Test

4

Deletion of the Pseudorabies Virus gE/gI-US9p complex disrupts kinesin KIF1A and KIF5C recruitment during egress, and alters the properties of microtubule-dependent transport in vitro

المؤلفون: Jenna Barnes, Allan W. Wolkoff, Drishya Diwaker, John W. Murray, Duncan W. Wilson

المصدر: PLoS Pathogens, Vol 16, Iss 6, p e1008597 (2020)
PLoS Pathogens

مصطلحات موضوعية: Cellular differentiation, viruses, Kinesins, Microtubules, Axonal Transport, Biochemistry, Virions, Nerve Fibers, Viral Envelope Proteins, Animal Cells, Axon, Biology (General), Virus Release, Cytoskeleton, Neurons, 0303 health sciences, biology, Chemistry, 030302 biochemistry & molecular biology, Intracellular Signaling Peptides and Proteins, Microtubule Motors, Cell Differentiation, Herpesvirus 1, Suid, Cell biology, medicine.anatomical_structure, Cell Processes, Virion assembly, Kinesin, Cellular Structures and Organelles, Cellular Types, Neuronal Differentiation, Research Article, Imaging Techniques, QH301-705.5, Lipoproteins, Immunology, Biological Transport, Active, Viral Structure, Research and Analysis Methods, Microbiology, Cell Line, Viral Proteins, 03 medical and health sciences, Molecular Motors, Microtubule, Virology, Fluorescence Imaging, Genetics, medicine, Animals, Humans, Molecular Biology, 030304 developmental biology, Pseudorabies, Biology and Life Sciences, Proteins, Cell Biology, Viral membrane, RC581-607, Axons, Cytoskeletal Proteins, Membrane glycoproteins, Cellular Neuroscience, biology.protein, Axoplasmic transport, Parasitology, Immunologic diseases. Allergy, Gene Deletion, Developmental Biology, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd0a65d1520fefc98e2c78bf40137dcTest
https://doaj.org/article/fccfc18945144d52943a48fe94b8ae36Test

5

A kinesin-3 recruitment complex facilitates axonal sorting of enveloped alpha herpesvirus capsids

المؤلفون: Benjamin Y. Winer, Lynn W. Enquist, Nikhila S. Tanneti, Michael Vershinin, Ian B. Hogue, Julian Scherer, Zachary A. Yaffe

المصدر: PLoS Pathogens, Vol 16, Iss 1, p e1007985 (2020)
PLoS Pathogens

مصطلحات موضوعية: Swine, viruses, Kinesins, Pseudorabies, Herpesvirus 1, Human, Pathology and Laboratory Medicine, Axonal Transport, Biochemistry, Nerve Fibers, 0302 clinical medicine, Viral Envelope Proteins, Animal Cells, Capsids, Medicine and Health Sciences, Axon, Biology (General), Neuronal transport, KIF1A, Neurons, 0303 health sciences, 030302 biochemistry & molecular biology, Microtubule Motors, Herpesvirus 1, Suid, 3. Good health, Cell biology, medicine.anatomical_structure, Cell Processes, Host-Pathogen Interactions, Kinesin, Cellular Types, Pathogens, Cellular Structures and Organelles, Research Article, Protein Binding, trans-Golgi Network, Pathogen Motility, Virulence Factors, QH301-705.5, Motor Proteins, Immunology, Viral Structure, Biology, Microbiology, Virus, Motor protein, 03 medical and health sciences, Capsid, Molecular Motors, Virology, Genetics, medicine, Animals, Humans, Vesicles, Molecular Biology, 030304 developmental biology, Biology and Life Sciences, Proteins, Herpes Simplex, Cell Biology, RC581-607, biology.organism_classification, Axons, Oncolytic virus, Cytoskeletal Proteins, nervous system, Cellular Neuroscience, Axoplasmic transport, Parasitology, Soma, Immunologic diseases. Allergy, 030217 neurology & neurosurgery, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b9ad52b88f2df357f74c5ae9161eceTest
https://doaj.org/article/71317a4be24b4fddb9605ed26a118fffTest

6

The role of microtubules and the dynein/ dynactin motor complex of host cells in the biogenesis of the Coxiella burnetii-containing vacuole

المؤلفون: Walter Berón, Rodolfo M. Ortiz Flores, Milton Osmar Aguilera, Jesús S. Distel

المصدر: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0209820 (2019)

مصطلحات موضوعية: Endocytic cycle, Cultured tumor cells, Kinesins, Pathology and Laboratory Medicine, Biochemistry, Microtubules, purl.org/becyt/ford/1 [https], Chlorocebus aethiops, Medicine and Health Sciences, Cytoskeleton, RILP-RAB7, 0303 health sciences, Multidisciplinary, Chemistry, 030302 biochemistry & molecular biology, Microtubule Motors, Dynactin Complex, COXIELLA BURNETII, Bacterial Pathogens, Cell biology, Vesicular transport protein, Actin Cytoskeleton, Protein Transport, Medical Microbiology, Coxiella burnetii, Medicine, Cell lines, Hyperexpression Techniques, Kinesin, Pathogens, Cellular Structures and Organelles, Biological cultures, Q Fever, CIENCIAS NATURALES Y EXACTAS, Research Article, Endosome, Science, Motor Proteins, Dynein, Endosomes, macromolecular substances, Biosynthesis, Microbiology, Ciencias Biológicas, Motor protein, 03 medical and health sciences, DYNEIN, Biología Celular, Microbiología, Molecular Motors, Microtubule, Gene Expression and Vector Techniques, Animals, Humans, HeLa cells, Molecular Biology Techniques, purl.org/becyt/ford/1.6 [https], Microbial Pathogens, Molecular Biology, Vero Cells, Adaptor Proteins, Signal Transducing, 030304 developmental biology, Molecular Biology Assays and Analysis Techniques, MICROTUBULE, Biology and Life Sciences, Proteins, Dyneins, rab7 GTP-Binding Proteins, Biological Transport, Cell Biology, Cell cultures, Research and analysis methods, Cytoskeletal Proteins, rab GTP-Binding Proteins, Vacuoles, Dynactin, Lysosomes

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f823424d797228cb8a186f49d05b3edTest
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209820Test

7

LIBRA-WA: a web application for ligand binding site detection and protein function recognition

المؤلفون: Valentina Tortosa, Valentina Brandi, Daniele Toti, Le Viet Hung, Fabio Polticelli

المساهمون: Toti, Daniele, Le, VIET HUNG, Tortosa, Valentina, Brandi, Valentina, Polticelli, Fabio

المصدر: Bioinformatics

مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Scheme (programming language), 030103 biophysics, Protein Conformation, Computer science, Interface (Java), Kinesins, Ligands, computer.software_genre, Settore INF/01 - INFORMATICA, Biochemistry, Ranking (information retrieval), 03 medical and health sciences, Software, Catalytic Domain, Humans, Web application, Binding site, Molecular Biology, computer.programming_language, Protein function, Binding Sites, business.industry, Ligand, Computational Biology, Proteins, Kinesin, Ligand (biochemistry), Applications Notes, Structural Bioinformatics, Computer Science Applications, Computational Mathematics, 030104 developmental biology, Computational Theory and Mathematics, Data mining, business, computer, Algorithms, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff5cfe9a9ea0c79e0fd01aa18b1c04dTest
https://doi.org/10.1093/bioinformatics/btx715Test

8

Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development

المؤلفون: Kanya Suphapeetiporn, Vorasuk Shotelersuk, Curtis W. Boswell, Elle C. Roberson, Patra Yeetong, Christina A. Gurnett, John B. Wallingford, Ryan S. Gray, Mia J. Konjikusic, Brian Ciruna, Rungnapa Ittiwut, Chanjae Lee

المصدر: PLoS Genetics, Vol 14, Iss 11, p e1007817 (2018)
PLoS Genetics

مصطلحات موضوعية: Male, 0301 basic medicine, Axoneme, Cancer Research, Physiology, Gene Expression, Kinesins, Artificial Gene Amplification and Extension, QH426-470, Nervous System, Polymerase Chain Reaction, Biochemistry, Animals, Genetically Modified, Consanguinity, Mice, Xenopus laevis, Medicine and Health Sciences, Basal body, Tissue Distribution, Child, Frameshift Mutation, Zebrafish, Genetics (clinical), Sequence Deletion, Cerebrospinal Fluid, Cilium, Homozygote, Microtubule Motors, Eukaryota, Animal Models, Pedigree, Body Fluids, Cell biology, Experimental Organism Systems, Neurology, Osteichthyes, Models, Animal, Vertebrates, Kinesin, Female, Cellular Structures and Organelles, Anatomy, Hydrocephalus, Research Article, Genetically modified mouse, Ependymal Cell, Mice, Transgenic, Mouse Models, Biology, Research and Analysis Methods, 03 medical and health sciences, Model Organisms, Molecular Motors, Ependyma, Intellectual Disability, Ciliogenesis, Genetics, Animals, Humans, Amino Acid Sequence, Cilia, Molecular Biology Techniques, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Base Sequence, Organisms, Biology and Life Sciences, Proteins, Cell Biology, biology.organism_classification, Cytoskeletal Proteins, Fish, 030104 developmental biology, Neurodevelopmental Disorders, Mutation, Animal Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04d29a6e3a5b3b4da9d0d52fab39443Test
https://doaj.org/article/18c7dedfa9844f2fa485a189e32020a4Test

9

دورية أكاديمية

LIBRA-WA: A web application for ligand binding site detection and protein function recognition

المؤلفون: Toti D.

المساهمون: Toti, Daniele, Viet Hung, L., Tortosa, V., Brandi, V., Polticelli, F.

مصطلحات موضوعية: Algorithms, Binding Sites, Computational Biology, Humans, Kinesin, Protein Binding, Protein Conformation, Proteins, Catalytic Domain, Ligands, Software, Settore INF/01 - INFORMATICA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29126218; info:eu-repo/semantics/altIdentifier/wos/WOS:000426813500025; volume:34; issue:5; firstpage:878; lastpage:880; numberofpages:3; issueyear:2018; journal:BIOINFORMATICS; http://hdl.handle.net/10807/163216Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85042938807

الإتاحة: https://doi.org/10.1093/bioinformatics/btx715Test
http://hdl.handle.net/10807/163216Test

View record in BASE

10

Role of kinesins in directed adenovirus transport and cytoplasmic exploration

المؤلفون: Julie Yi, Julian Scherer, Jie Zhou, Richard B. Vallee

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 5, p e1007055 (2018)

مصطلحات موضوعية: 0301 basic medicine, Adenoviruses, viruses, Adenoviridae Infections, Kinesins, Pathology and Laboratory Medicine, Biochemistry, Microtubules, RNA interference, Cytosol, Capsids, Medicine and Health Sciences, Small interfering RNAs, lcsh:QH301-705.5, Cytoskeleton, Chemistry, Microtubule Motors, 3. Good health, Cell biology, Nucleic acids, Genetic interference, Medical Microbiology, Viral Pathogens, Viruses, Kinesin, Epigenetics, Pathogens, Cellular Structures and Organelles, Transcytosis, Research Article, lcsh:Immunologic diseases. Allergy, Immunology, Dynein, Motor Proteins, Viral Structure, Microbiology, Adenoviridae, Cell Line, Motor protein, 03 medical and health sciences, Capsid, Microtubule, Molecular Motors, Virology, Genetics, Humans, Non-coding RNA, Molecular Biology, Microbial Pathogens, Cell Nucleus, Organisms, Biology and Life Sciences, Proteins, Dyneins, Epithelial Cells, Cell Biology, Gene regulation, Microtubule minus-end, Cytoskeletal Proteins, 030104 developmental biology, HEK293 Cells, lcsh:Biology (General), Cytoplasm, Centrosome, A549 Cells, KIF4A, RNA, Parasitology, Capsid Proteins, Gene expression, lcsh:RC581-607, DNA viruses

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ad0d5efa734130d209606df1f9d7e9Test
http://europepmc.org/articles/PMC5983873Test

تنقيح النتائج