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1
المؤلفون: Jacek Lubkowski, Andriy Anishkin, Alexander Wlodawer, Cem Sonmez, Sergei V. Kotenko, Sergey V. Smirnov
المصدر: The Journal of Immunology. 201:2082-2093
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Immunology, Plasma protein binding, Crystallography, X-Ray, Article, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Protein Domains, Animals, Humans, Immunology and Allergy, Receptor, Ternary complex, Schneider 2 cells, Chemistry, Interleukins, Receptors, Interleukin, Ligand (biochemistry), 030104 developmental biology, Multiprotein Complexes, 030220 oncology & carcinogenesis, Biophysics, Cytokines, Drosophila, Signal transduction, Protein Binding, Signal Transduction, Cysteine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fa097b0d4504e21e04988fe7b10b39Test
https://doi.org/10.4049/jimmunol.1800726Test -
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المؤلفون: Mei Hong, Tim Doherty, Cyril Barinka, Jing Li, Wuyuan Lu, Yuan Zhang, Jacek Lubkowski
المصدر: Journal of Molecular Biology. 397:408-422
مصطلحات موضوعية: Models, Molecular, alpha-Defensins, Protein Conformation, Chemistry, Protein Data Bank (RCSB PDB), Dihedral angle, Article, Alpha defensin, Protein Structure, Tertiary, Crystallography, Membrane, Protein structure, Solid-state nuclear magnetic resonance, Structural Biology, Humans, Lipid bilayer, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, Defensin
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30657b07641af72b9ae49e67ece5a43Test
https://doi.org/10.1016/j.jmb.2010.01.030Test -
3
المؤلفون: Jacek Lubkowski, Youngjoo Byun, Cyril Barinka, Alan P. Kozikowski, Crystal L. Dusich, Martin G. Pomper, Sangeeta Ray Banerjee, Mark Castanares, Ying Chen, Ronnie C. Mease
المصدر: Journal of Medicinal Chemistry. 51:7737-7743
مصطلحات موضوعية: Glutamate Carboxypeptidase II, Models, Molecular, Protein Conformation, Stereochemistry, Chemistry, Pharmaceutical, Molecular Conformation, Glutamic Acid, Ligands, Article, Protein structure, Drug Discovery, Hydrolase, Glutamate carboxypeptidase II, Humans, Urea, Moiety, Binding site, Ions, Binding Sites, biology, Chemistry, Active site, Glutamic acid, Carboxypeptidase, Protein Structure, Tertiary, Zinc, Drug Design, biology.protein, Tyrosine, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541915582298f31d946bafb09398a3ddTest
https://doi.org/10.1021/jm800765eTest -
4
المؤلفون: Jacek Lubkowski, Xiangqun Li, Wuyuan Lu, Marzena Pazgier
المصدر: Current Pharmaceutical Design. 13:3096-3118
مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Molecular Sequence Data, Computational biology, Biology, Crystallography, X-Ray, Receptors, G-Protein-Coupled, Defensins, Structure-Activity Relationship, Immune system, Protein structure, Anti-Infective Agents, Drug Discovery, Humans, Structure–activity relationship, Amino Acid Sequence, Peptide sequence, Antibacterial agent, Pharmacology, Innate immune system, integumentary system, fungi, hemic and immune systems, respiratory system, bacterial infections and mycoses, Acquired immune system, Immunity, Innate, Recombinant Proteins, Protein Structure, Tertiary, Human genome
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e99b9c01531ef2497c78541e268560Test
https://doi.org/10.2174/138161207782110381Test -
5
المؤلفون: Jacek Lubkowski, Adam Prahl, David M. Hoover, Marzena Pazgier
المصدر: Journal of Biological Chemistry. 282:1819-1829
مصطلحات موضوعية: beta-Defensins, Molecular Sequence Data, Mutant, Mutagenesis (molecular biology technique), Biology, Arginine, Crystallography, X-Ray, Transfection, medicine.disease_cause, Biochemistry, Epitopes, Protein structure, Escherichia coli, Serine, medicine, Humans, Point Mutation, Amino Acid Sequence, Disulfides, Molecular Biology, Peptide sequence, Defensin, Lysine, C-terminus, Cell Biology, Protein tertiary structure, Protein Structure, Tertiary, Mutagenesis
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef28da900c499c29d5e15f2ada85411Test
https://doi.org/10.1074/jbc.m607210200Test -
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المؤلفون: Cyril Boulègue, Wuyuan Lu, Jacek Lubkowski, David M. Hoover, Oluwatoyin A. Asojo
المصدر: Acta Crystallographica Section D Biological Crystallography. 59:1165-1173
مصطلحات موضوعية: Chemokine, Molecular Structure, biology, Protein Conformation, Stereochemistry, Chemistry, General Medicine, Crystal structure, Triclinic crystal system, CCR8, Crystallography, X-Ray, Antiparallel (biochemistry), Protein tertiary structure, Protein structure, Structural Biology, Chemokines, CC, biology.protein, Humans, Molecular replacement, Amino Acid Sequence, Chemokine CCL17, Crystallization, Sequence Alignment, Glycosaminoglycans, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686487fef590e9e90e1637bb6705bd84Test
https://doi.org/10.1107/s0907444903009454Test -
7
المؤلفون: Jan Konvalinka, Ronnie C. Mease, Martin G. Pomper, Lubica Skultetyova, Hyung Joon Kim, Glenda Alquicer, Lubomír Rulíšek, Youngjoo Byun, Adriana Němcová, Anna Plechanovová, Michal Navrátil, Cyril Bařinka, Petra Mlčochová, Jacek Lubkowski
مصطلحات موضوعية: Glutamate Carboxypeptidase II, Models, Molecular, Stereochemistry, Protein Conformation, Crystallography, X-Ray, Ligands, Molecular mechanics, Article, Substrate Specificity, Structure-Activity Relationship, Protein structure, Drug Discovery, Glutamate carboxypeptidase II, Structure–activity relationship, Humans, Binding site, Binding Sites, biology, Chemistry, Substrate (chemistry), Dipeptides, Carboxypeptidase, Kinetics, Lipophilicity, Antigens, Surface, biology.protein, Mutagenesis, Site-Directed, Molecular Medicine, Quantum Theory, Thermodynamics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff1164cb2bd21f93e477c1c61b72127Test
https://europepmc.org/articles/PMC3222833Test/ -
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المؤلفون: Anna Plechanovová, Jacek Lubkowski, Petra Mlčochová, Klára Hlouchová, Barbara S. Slusher, Jan Konvalinka, Takashi Tsukamoto, Cyril Barinka, Pavel Majer, Miroslava Rovenska
المصدر: Journal of medicinal chemistry. 50(14)
مصطلحات موضوعية: Glutamate Carboxypeptidase II, Models, Molecular, biology, Molecular model, Chemistry, Stereochemistry, Protein Conformation, Molecular Mimicry, Biological activity, Crystallography, X-Ray, Recombinant Proteins, chemistry.chemical_compound, Protein structure, Biochemistry, Enzyme inhibitor, Drug Discovery, Hydrolase, Glutamate carboxypeptidase II, biology.protein, Molecular Medicine, Humans, Quisqualic acid, Pharmacophore
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4832dccf02284c652780d3705fd4a2d6Test
https://pubmed.ncbi.nlm.nih.gov/17567119Test -
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المؤلفون: Maia M. Chisholm, Jacek Lubkowski, Agnieszka Szyk, A. Valance Washington, Daniel W. McVicar, James Gattis, Laura Quigley
المصدر: The Journal of biological chemistry. 281(19)
مصطلحات موضوعية: Blood Platelets, Models, Molecular, Protein Conformation, Immunoglobulin domain, Biology, Biochemistry, Cell Line, Cell membrane, Mice, Protein structure, medicine, Extracellular, Animals, Humans, Receptors, Immunologic, Receptor, Molecular Biology, Thrombin, Cell Biology, Platelet Activation, Molecular biology, Transmembrane protein, Recombinant Proteins, Protein Structure, Tertiary, medicine.anatomical_structure, Gene Expression Regulation, Cell culture, Polymeric immunoglobulin receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ef954c9917d1ec62af8d7f39401b90Test
https://pubmed.ncbi.nlm.nih.gov/16505478Test -
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المؤلفون: David M. Hoover, Laurent Picard, Jacek Lubkowski, Helen McSparron, Darren A. Thompson, Alexander Wlodawer, Paul N. Barlow, Stephen B. H. Kent, Jill Wilken
المصدر: Chemistrybiology. 6(1)
مصطلحات موضوعية: Models, Molecular, crystal structure, Chemokine, Protein Folding, Magnetic Resonance Spectroscopy, Chemokine receptor CCR5, Stereochemistry, Anti-HIV Agents, Protein Conformation, chemical protein synthesis, Clinical Biochemistry, Molecular Sequence Data, Crystallography, X-Ray, Chemical synthesis, Biochemistry, law.invention, RANTES, Chemokine receptor, Protein structure, law, Drug Discovery, Humans, Amino Acid Sequence, Peptide sequence, Molecular Biology, Chemokine CCL5, Pharmacology, biology, Chemistry, chemokine, General Medicine, HIV-1, biology.protein, Recombinant DNA, Molecular Medicine, Protein folding, Peptides
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e305eaa9c301846a77b522b7966526Test
https://pubmed.ncbi.nlm.nih.gov/9889151Test