المؤلفون: Ross Chawner, Sonia Mazzitelli, Ross Jeggo, Claire E. Eyers, David Spanswick, Jasmeet Virdee, J. Mark Treherne, Alun Williams, David I.C. Scopes, Hozefa Amijee, Clive Bate, Andrew J. Doig

المصدر: Biochemistry. 51:8338-8352

مصطلحات موضوعية: Male, Programmed cell death, Circular dichroism, Cell Survival, Long-Term Potentiation, Peptide, Biochemistry, Oligomer, Mice, chemistry.chemical_compound, Alzheimer Disease, Lactate dehydrogenase, Tumor Cells, Cultured, Animals, Humans, Benzothiazoles, Protein Structure, Quaternary, Neurons, chemistry.chemical_classification, Amyloid beta-Peptides, Circular Dichroism, Long-term potentiation, Surface Plasmon Resonance, Peptide Fragments, Rats, Thiazoles, chemistry, Toxicity, Thioflavin, Protein Multimerization, Oligopeptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222e325f86e334145f0d7f75c2c725e9Test
https://doi.org/10.1021/bi300415vTest

المؤلفون: Victoria Ingham, Alun Williams, Clive Bate

المصدر: Neuropharmacology. 60:365-372

مصطلحات موضوعية: Gene isoform, Phospholipase A2 Inhibitors, Prions, Organophosphonates, Peptide, Arachidonic Acids, Biology, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Phospholipase A2, Animals, Humans, Receptor, Lipid raft, Cells, Cultured, Cerebral Cortex, Neurons, Pharmacology, chemistry.chemical_classification, Phospholipase A, Platelet-activating factor, Cholesterol, Peptide Fragments, Cell biology, Phospholipases A2, Protein Transport, chemistry, Biochemistry, biology.protein, lipids (amino acids, peptides, and proteins)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727fa08e89f717e9c89224629290d756Test
https://doi.org/10.1016/j.neuropharm.2010.10.001Test

المؤلفون: Mourad Tayebi, Alun Williams, Luisa Diomede, Clive Bate, Mario Salmona

المصدر: Neurotoxicity Research. 17:203-214

مصطلحات موضوعية: Simvastatin, Docosahexaenoic Acids, Prions, animal diseases, Synaptophysin, Enzyme-Linked Immunosorbent Assay, In Vitro Techniques, Hippocampal formation, Neurotransmission, Toxicology, Hippocampus, Synapse, Mice, Animals, Humans, Neurotoxin, Drug Interactions, Cells, Cultured, Cerebral Cortex, Mice, Knockout, Neurons, chemistry.chemical_classification, Dose-Response Relationship, Drug, biology, Caspase 3, General Neuroscience, Embryo, Mammalian, Eicosapentaenoic acid, Peptide Fragments, nervous system diseases, Cell biology, Neuroprotective Agents, Eicosapentaenoic Acid, Gene Expression Regulation, nervous system, chemistry, Biochemistry, Docosahexaenoic acid, Fatty Acids, Unsaturated, biology.protein, lipids (amino acids, peptides, and proteins), Hydroxymethylglutaryl-CoA Reductase Inhibitors, Synaptosomes, Polyunsaturated fatty acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5351409a315ff0f09ced6daba2de3c03Test
https://doi.org/10.1007/s12640-009-9093-2Test

المؤلفون: Alun Williams, Harriet McHale-Owen, Clive Bate, William Nolan, Craig Osborne, Ewan West

المصدر: Neuropharmacology. 101

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Cell signaling, Prions, Synaptophysin, Enzyme-Linked Immunosorbent Assay, Cell Membrane Structures, Synapse, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Phospholipase A2, Alzheimer Disease, Internal medicine, medicine, Humans, Cognitive decline, Receptor, Cells, Cultured, Aged, Pharmacology, Neurons, Amyloid beta-Peptides, biology, medicine.disease, Peptide Fragments, Temporal Lobe, Cell biology, Glimepiride, Phospholipases A2, 030104 developmental biology, Endocrinology, Cholesterol, Sulfonylurea Compounds, biology.protein, Female, Alzheimer's disease, 030217 neurology & neurosurgery, Immunosuppressive Agents, medicine.drug, Synaptosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d25fa67e0af330b43255e00784097eTest
https://pubmed.ncbi.nlm.nih.gov/26432105Test

المؤلفون: Ronald S. Boshuizen, Clive Bate, Alun Williams

المصدر: Journal of Neuroimmunology. 170:62-70

مصطلحات موضوعية: Cell Survival, Prions, medicine.drug_class, Recombinant Fusion Proteins, CD14, Immunology, Lipopolysaccharide Receptors, Peptide, Monoclonal antibody, Antibodies, Monocytes, Epitope, Epitopes, Mice, Chimera (genetics), medicine, Animals, Humans, Immunology and Allergy, Cells, Cultured, Cerebral Cortex, Mice, Knockout, Neurons, chemistry.chemical_classification, Cell Death, biology, Antibodies, Monoclonal, Molecular biology, Coculture Techniques, Peptide Fragments, In vitro, Mice, Inbred C57BL, nervous system, Neurology, chemistry, Immunoglobulin G, Knockout mouse, biology.protein, Microglia, Neurology (clinical), Antibody, Epitope Mapping

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9620daf56f0981058c098de0d6c31155Test
https://doi.org/10.1016/j.jneuroim.2005.08.021Test

المؤلفون: Victoria Ingham, Alun Williams, Clive Bate

المصدر: Journal of Neuroinflammation

مصطلحات موضوعية: Lipopolysaccharides, Receptor complex, medicine.medical_specialty, Time Factors, Prions, CD14, medicine.medical_treatment, Immunology, Lipopolysaccharide Receptors, Biology, Pharmacology, Cellular and Molecular Neuroscience, Membrane Microdomains, Internal medicine, medicine, Animals, Humans, Hypoglycemic Agents, Cells, Cultured, Mice, Knockout, Amyloid beta-Peptides, Microglia, Dose-Response Relationship, Drug, General Neuroscience, Macrophages, Research, Peptide Fragments, Mice, Inbred C57BL, Glimepiride, Cytokine, medicine.anatomical_structure, Endocrinology, Sulfonylurea Compounds, Neurology, Gene Expression Regulation, Cytokines, Cytokine secretion, Tumor necrosis factor alpha, Cell activation, Neuroglia, Glipizide, Immunosuppressive Agents, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05affdca7acbf94273220140472f2c83Test
https://pubmed.ncbi.nlm.nih.gov/24952384Test

المؤلفون: Dirk Werling, Alun Williams

المساهمون: Williams, Alun [0000-0003-0835-0200], Apollo - University of Cambridge Repository

المصدر: BMC Neuroscience, Vol 13, Iss 1, p 106 (2012)
BMC Neuroscience

مصطلحات موضوعية: Time Factors, Phospholipases A2, Cytosolic, Synapse, Mice, Phospholipase A2, Tubulin, Drug Interactions, Enzyme Inhibitors, Cytoskeleton, Cells, Cultured, Cerebral Cortex, Neurons, Arachidonic Acid, biology, Cell Death, Chemistry, General Neuroscience, Ionomycin, Neurodegeneration, lcsh:QP351-495, Ketones, Cell biology, Protein Transport, Tetradecanoylphorbol Acetate, lipids (amino acids, peptides, and proteins), Intracellular, Research Article, Neurite, Prions, Synaptophysin, Tritium, PACOCF3, lcsh:RC321-571, Cellular and Molecular Neuroscience, medicine, Neurotoxicity, Animals, Humans, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Analysis of Variance, Dose-Response Relationship, Drug, medicine.disease, Embryo, Mammalian, Peptide Fragments, Enzyme Activation, lcsh:Neurophysiology and neuropsychology, Gene Expression Regulation, biology.protein

وصف الملف: text/xml; application/pdf; image/tiff

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9bd5d5bea60e0331f0cb4a95c3cf7a1Test
http://www.biomedcentral.com/1471-2202/13/106Test

المؤلفون: Valentina Bonetto, Alun Williams, Claudia Manzoni, Laura Colombo, Mauro Pignataro, Cristina Airoldi, Alfredo Cagnotto, Mario Salmona, Erika Sironi, Paolo Bigini, Valentina Diana, Monica Lupi, Massimo Messa

المساهمون: Amédée, T, Manzoni, C, Colombo, L, Bigini, P, Diana, V, Cagnotto, A, Messa, M, Lupi, M, Bonetto, V, Pignataro, M, Airoldi, C, Sironi, E, Williams, A, Salmona, M

المصدر: PLoS ONE, Vol 6, Iss 9, p e24909 (2011)
PLoS ONE

مصطلحات موضوعية: Cytoplasm, Amyloid, Cell Survival, lcsh:Medicine, Biology, Blotting, Far-Western, Endoplasmic Reticulum, Cathepsin D, Biochemistry, Protein Chemistry, Cell Line, Tumor, medicine, Animals, Humans, Vimentin, Receptor, lcsh:Science, Integral membrane protein, Endoplasmic Reticulum Chaperone BiP, Cytoskeleton, Heat-Shock Proteins, Multidisciplinary, Amyloid beta-Peptides, lcsh:R, Neurotoxicity, P3 peptide, Proteins, Long-term potentiation, medicine.disease, N2a cell, Immunohistochemistry, Peptide Fragments, Cell biology, Membrane protein, Aβ oligomers, amyloid toxicity, Far Western blot, N2a cells, proteomic analysis, protein binding, Microscopy, Fluorescence, Cellular Neuroscience, lcsh:Q, Protein Multimerization, Molecular Neuroscience, Lysosomes, Protein Binding, Research Article, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f1a28e3934d8d5168b08cbf87088f5Test
http://europepmc.org/articles/PMC3179491?pdf=renderTest

المؤلفون: Alun Williams, Clive Bate

المصدر: Neuropharmacology. 53(2)

مصطلحات موضوعية: Cytoplasm, Simvastatin, Statin, medicine.drug_class, Cell Survival, Caveolin 1, Enzyme-Linked Immunosorbent Assay, Biology, Neuroprotection, Synapse, Cellular and Molecular Neuroscience, Mice, Neuroblastoma, Phospholipase A2, medicine, Animals, Humans, Immunoprecipitation, Pharmacokinetics, Prostaglandin E2, Lipid raft, Cells, Cultured, Pharmacology, Neurons, Phospholipase A, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Brain, Bridged Bicyclo Compounds, Heterocyclic, Embryo, Mammalian, Peptide Fragments, Cell biology, Enzyme Activation, Phospholipases A2, Neuroprotective Agents, Biochemistry, biology.protein, lipids (amino acids, peptides, and proteins), medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a70b06f278d2658e04e59845ecc6f5Test
https://pubmed.ncbi.nlm.nih.gov/17583757Test

المؤلفون: Alun Williams, Clive Bate, Mario Salmona

المصدر: Neuroreport. 15(3)

مصطلحات موضوعية: Amyloid beta, Prions, animal diseases, Pharmacology, Dinoprostone, Phospholipases A, chemistry.chemical_compound, Neuroblastoma, Phospholipase A2, medicine, Tumor Cells, Cultured, Humans, Prostaglandin E2, Platelet Activating Factor, Phospholipase A, Amyloid beta-Peptides, biology, Platelet-activating factor, Cell Death, Brain Neoplasms, Caspase 3, General Neuroscience, Neurodegeneration, Neurotoxicity, medicine.disease, Peptide Fragments, nervous system diseases, Phospholipases A2, Biochemistry, chemistry, Caspases, biology.protein, Alzheimer's disease, Nervous System Diseases, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b9872898e204e9f74c85f3eb564efbTest
https://pubmed.ncbi.nlm.nih.gov/15094513Test