دورية أكاديمية
A prospective, one-year follow-up study of patients newly diagnosed with neurosarcoidosis
| العنوان: | A prospective, one-year follow-up study of patients newly diagnosed with neurosarcoidosis |
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| المؤلفون: | Byg, Keld-Erik, Illés, Zsolt, Sejbæk, Tobias, Nguyen, Nina N. T. T., Möller, Sören, Lambertsen, Kate Lykke, Nielsen, Helle Hvilsted, Ellingsen, Torkell Juulsgaard |
| المصدر: | Byg , K-E , Illés , Z , Sejbæk , T , Nguyen , N N T T , Möller , S , Lambertsen , K L , Nielsen , H H & Ellingsen , T J 2022 , ' A prospective, one-year follow-up study of patients newly diagnosed with neurosarcoidosis ' , Journal of Neuroimmunology , vol. 369 , 577913 . https://doi.org/10.1016/j.jneuroim.2022.577913Test |
| سنة النشر: | 2022 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| مصطلحات موضوعية: | FAS, MRI, Neurosarcoidosis, SDMT, Treatment, mRS, Neuropsychological Tests, Central Nervous System Diseases/diagnostic imaging, Prospective Studies, Follow-Up Studies, Sarcoidosis, Humans |
| الوصف: | Methods: Twenty patients with newly diagnosed neurosarcoidosis were examined for multiple outcomes in an observational cohort study with 12-month follow-up. Results: The patients' contrast-enhancing lesions on MRI scans reduced during treatment (p < 0.0001). The mean modified Rankin Score improved from 3.0 to 1.8 (p < 0.0001), and 75% of patients experienced clinically important improvement. Patients improved on the Symbol Digit Modalities Test (p < 0.0001) and on SF-36 Physical (p = 0.003) and Mental Component Summary scores (p = 0.03). Proportions of patients with substantial fatigue (75%) and high depression score (35%) were unchanged. Conclusions: 12-month immunosuppression improved several outcomes, and 75% of patients experienced clinically important improvement. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://portal.findresearcher.sdu.dk/da/publications/4dc7e180-23cc-4138-8a31-a6bd0f5a8cffTest |
| DOI: | 10.1016/j.jneuroim.2022.577913 |
| الإتاحة: | https://doi.org/10.1016/j.jneuroim.2022.577913Test https://portal.findresearcher.sdu.dk/da/publications/4dc7e180-23cc-4138-8a31-a6bd0f5a8cffTest https://findresearcher.sdu.dk/ws/files/206092580/Open_Access_Version.pdfTest |
| حقوق: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.3F40D32E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.jneuroim.2022.577913 |
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