المؤلفون: Ana Katušić-Bojanac, Milvija Plazibat, Marta Himelreich-Perić, Katarina Eck-Raković, Jure Krasić, Nino Sinčić, Gordana Jurić-Lekić, Davor Ježek, Floriana Bulić-Jakuš

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8861

مصطلحات موضوعية: Placenta, Histone Deacetylases, Catalysis, Inorganic Chemistry, Pregnancy, Animals, Humans, Physical and Theoretical Chemistry, valproate, HDACi, neural tissue, ectoplacental cone, embryo, Molecular Biology, Spectroscopy, Placenta / metabolism, Mammals, Valproic Acid / pharmacology, Valproic Acid, Organic Chemistry, Gastrulation, Mammals / metabolism, Acetylation, General Medicine, Histone Deacetylase Inhibitors / pharmacology, Computer Science Applications, Rats, Histone Deacetylase Inhibitors, Histone Deacetylases / metabolism, Female

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94172e33185d6c105d2d22ab302ee8bTest

المؤلفون: Nico Fischer, Tina Dahlby, Melissa Koomen, Thomas Mandrup-Poulsen, Charna Dibner, Volodymyr Petrenko, Phillip Alexander Keller Andersen, Seyed Mojtaba Ghiasi, Peter Horskjær Rose

المصدر: International Journal of Molecular Sciences
Andersen, P A K, Petrenko, V, Rose, P H, Koomen, M, Fischer, N, Ghiasi, S M, Dahlby, T, Dibner, C & Mandrup-Poulsen, T 2021, ' Proinflammatory cytokines perturb mouse and human pancreatic islet circadian rhythmicity and induce uncoordinated β-cell clock gene expression via nitric oxide, lysine deacetylases, and immunoproteasomal activity ', International Journal of Molecular Sciences, vol. 22, no. 1, 83, pp. 1-25 . https://doi.org/10.3390/ijms22010083Test
International Journal of Molecular Sciences, Vol. 22, No 1 (2020) P. 83
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 83, p 83 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Interferon-gamma/metabolism/pharmacology, lcsh:Chemistry, Mice, 0302 clinical medicine, ARNTL Transcription Factors/genetics/metabolism, Insulin-Secreting Cells, Insulin, immuno-metabolism, lcsh:QH301-705.5, Spectroscopy, Cells, Cultured, ddc:616, Tumor, Cultured, diabetes, Chemistry, nitric oxide synthase, Diabetes, ARNTL Transcription Factors, General Medicine, Computer Science Applications, 3. Good health, Cell biology, Circadian Rhythm, CLOCK, PER2, medicine.anatomical_structure, Knockout mouse, Epigenetics, Female, Proteasome Endopeptidase Complex, Insulin/metabolism, Cells, Period (gene), Insulin-Secreting Cells/drug effects/metabolism, 030209 endocrinology & metabolism, Nitric Oxide, Catalysis, Article, Histone Deacetylases, Cell Line, Proinflammatory cytokine, Inorganic Chemistry, 03 medical and health sciences, Interferon-gamma, Reactive Oxygen Species/metabolism, Cell Line, Tumor, medicine, biochemistry, Animals, Humans, Viability assay, Physical and Theoretical Chemistry, ddc:612, Molecular Biology, epigenetics, Pancreatic islets, Nitric oxide synthase, Organic Chemistry, HDAC3, Proteasome Endopeptidase Complex/metabolism, 030104 developmental biology, HEK293 Cells, lcsh:Biology (General), lcsh:QD1-999, Nitric Oxide/metabolism, Histone Deacetylases/metabolism, chronobiology, Reactive Oxygen Species, Chronobiology, Immuno-metabolism

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f713196105e260c2898cb08ff9e574Test
http://europepmc.org/articles/PMC7795908Test

المؤلفون: Egbert K. O. Kruithof, Sylvie Dunoyer-Geindre

المصدر: Cardiovascular Research, Vol. 90, No 3 (2011) pp. 457-63
Cardiovascular research

مصطلحات موضوعية: Tissue Plasminogen Activator/biosynthesis/genetics, RNA, Messenger/genetics/metabolism, Physiology, Histones/metabolism, 030204 cardiovascular system & hematology, Epigenesis, Genetic/drug effects, Histone Deacetylases, Epigenesis, Genetic, Histones, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Humans, RNA, Messenger, Epigenetics, Promoter Regions, Genetic, Cells, Cultured, DNA Primers, 030304 developmental biology, ddc:616, DNA Primers/genetics, 0303 health sciences, Base Sequence, biology, T-plasminogen activator, Hepatocytes/metabolism, Endothelial Cells, DNA Methylation, Molecular biology, Histone Deacetylase Inhibitors, Endothelial Cells/drug effects/metabolism, Histone, PCAF, Acetylation, Tissue Plasminogen Activator, DNA methylation, Hepatocytes, biology.protein, Histone Deacetylases/metabolism, Histone deacetylase, Cardiology and Cardiovascular Medicine, Plasminogen activator, Histone Deacetylase Inhibitors/pharmacology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d74d00f0995ff382c4671138dfe0327Test
http://doc.rero.ch/record/296785/files/cvr028.pdfTest

المؤلفون: Krieger, Viktoria, Hamacher, Alexandra, Gertzen, Christoph, Senger, Johanna, Zwinderman, Martijn, Marek, Martin, Romier, Christophe, Dekker, Frank, Kurz, Thomas, Jung, Manfred, Gohlke, Holger, Kassack, Matthias, Hansen, Finn

المساهمون: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Journal of Medical Chemistry ; https://hal.science/hal-03682266Test ; Journal of Medical Chemistry, 2017, 60 (13), pp.5493-5506. ⟨10.1021/acs.jmedchem.7b00197⟩ ; http://www.ncbi.nlm.nih.gov/pubmed/28574690Test

مصطلحات موضوعية: Antineoplastic Agents/chemical synthesis/chemistry/*pharmacology, Cell Line, Tumor, Cell Proliferation/drug effects, Dose-Response Relationship, Drug, Drug Design, Drug Screening Assays, Antitumor, Histone Deacetylase Inhibitors/chemical synthesis/chemistry/*pharmacology, Histone Deacetylases/*metabolism, Humans, Models, Molecular, Molecular Structure, Peptoids/chemical synthesis/chemistry/*pharmacology, Small Molecule Libraries/chemical synthesis/chemistry/*pharmacology, Structure-Activity Relationship, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: hal-03682266; https://hal.science/hal-03682266Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.7b00197Test
https://hal.science/hal-03682266Test

المؤلفون: Stenzel, Katharina, Hamacher, Alexandra, Hansen, Finn, Gertzen, Christoph, Senger, Johanna, Marquardt, Viktoria, Marek, Linda, Marek, Martin, Romier, Christophe, Remke, Marc, Jung, Manfred, Gohlke, Holger, Kassack, Matthias, Kurz, Thomas

المساهمون: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0022-2623.

مصطلحات موضوعية: Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Histone Deacetylase Inhibitors/chemical synthesis/chemistry/*pharmacology, Histone Deacetylases/*metabolism, Humans, Molecular Docking Simulation, Molecular Structure, Structure-Activity Relationship, Antineoplastic Agents/chemistry/*pharmacology, Apoptosis/drug effects, Cell Line, Tumor, Cell Proliferation/drug effects, Cisplatin/chemistry/*pharmacology, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: hal-03691179; https://hal.science/hal-03691179Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.6b01538Test
https://hal.science/hal-03691179Test

المؤلفون: Team1 Carmen, Hubert VIDAL, Team2 Carmen, Luciano Pirola, Carmen Lab

المساهمون: Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL)

المصدر: Biochemistry and Cell Biology
Biochemistry and Cell Biology, NRC Research Press, 2014, 92 (1), pp.61-7. ⟨10.1139/bcb-2013-0071⟩

مصطلحات موضوعية: Histones/*metabolism, medicine.drug_class, [SDV]Life Sciences [q-bio], Muscle Fibers, Skeletal, 030209 endocrinology & metabolism, SAP30, Biology, Muscle Fibers, Biochemistry, Histone Deacetylases, Histones, Promoter Regions, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Hexokinase/metabolism, Insulin/*metabolism/pharmacology, 0302 clinical medicine, Genetic, Histone H1, Hexokinase, Histone H2A, medicine, Insulin, Humans, Animals, Histone code, Promoter Regions, Genetic, Molecular Biology, Transcription Initiation Site, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Histone deacetylase 2, Histone deacetylase inhibitor, Acetylation, Cell Biology, HDAC4, Molecular biology, Rats, Class Ia Phosphatidylinositol 3-Kinase, Class Ia Phosphatidylinositol 3-Kinase/metabolism, Gene Expression Regulation, Insulin Receptor Substrate Proteins, Histone Deacetylases/metabolism, Insulin Receptor Substrate Proteins/metabolism, Histone deacetylase, Phosphatidylinositol 3-Kinases/metabolism, Skeletal/drug effects/*metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313ee74892e18d034649a649e0cef462Test
https://doi.org/10.1139/bcb-2013-0071Test

المؤلفون: Judit Ovádi, Claudia A. Simões-Pires, Attila Lehotzky, Alessandra Nurisso, Philippe Bertrand, Muriel Cuendet, Nadine Martinet, Samuel Bouchet, Vincent Zwick, Christophe Blanquart

المساهمون: School of Pharmaceutical Sciences, Université de Lausanne (UNIL)-University of Geneva [Switzerland], Réseau épigénétique, Cancéropôle Grand-Ouest, Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP), Université de Poitiers-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie de Nice (ICN), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Institute of Enzymology [Budapest], Research Centre for Natural Sciences, Hungarian Academy of Sciences (MTA)-Hungarian Academy of Sciences (MTA), Centre de Recherche en Cancérologie Nantes-Angers (CRCNA), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Hôtel-Dieu de Nantes-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Laennec-Centre National de la Recherche Scientifique (CNRS)-Faculté de Médecine d'Angers-Centre hospitalier universitaire de Nantes (CHU Nantes), Authors thank the Centre National de la Recherche Scientifique– France, University of Poitiers, Region Poitou-Charentes (S.B. financial support), the Ligue Contre le Cancer: Committees of Vendée, et Charente-Maritime – France, ARSMeso44 – France, COST Actions CM1406 and CM1106 – Belgium and Hungarian OTKA Founds K-101039 and K-112144 for financial support. A.N. thanks the Excellence programme of the University of Geneva –Switzerland for financial support., Bernardo, Elizabeth, Université de Lausanne = University of Lausanne (UNIL)-Université de Genève = University of Geneva (UNIGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS)

المصدر: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2016, ⟨10.1016/j.bmcl.2015.11.011⟩
Bioorganic and Medicinal Chemistry Letters, 2016, ⟨10.1016/j.bmcl.2015.11.011⟩
Bioorganic & Medicinal Chemistry Letters, Vol. 26, No 1 (2016) pp. 154-159

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Intrinsic activity, Formic Acid Esters, Stereochemistry, Clinical Biochemistry, Convergent synthesis, Pharmaceutical Science, [SDV.CAN]Life Sciences [q-bio]/Cancer, Alkenes, Hydroxamic Acids, Metathesis, Biochemistry, Histone Deacetylases, Catalysis, Dose-Response Relationship, Formic Acid Esters/chemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, [SDV.CAN] Life Sciences [q-bio]/Cancer, Models, Drug Discovery, Humans, Structure–activity relationship, Benzamides/chemistry, Benzamide, Molecular Biology, ddc:615, Dose-Response Relationship, Drug, Molecular Structure, biology, Organic Chemistry, Molecular, Alkenes/chemistry, 3. Good health, Histone Deacetylase Inhibitors, 030104 developmental biology, Tubulin, Histone Deacetylase Inhibitors/chemistry/pharmacology, Hydroxamic Acids/chemistry, chemistry, Benzamides, biology.protein, Molecular Medicine, Histone Deacetylases/metabolism, Drug, Selectivity

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc9fefa73c13b45a09cef22d951db0cTest
https://www.hal.inserm.fr/inserm-01299475/documentTest

المؤلفون: Fang Zhang, F. Donelson Smith, Alexandra C. Newton, Dario Diviani, Lorene K. Langeberg, John D. Scott, Joseph Soughayer, Michael R. Bristow, Maya T. Kunkel, Graeme K. Carnegie, Benjamin S. Pedroja

المصدر: Molecular Cell, vol. 32, no. 2, pp. 169-179

مصطلحات موضوعية: 14-3-3 Proteins/metabolism, A Kinase Anchor Proteins/genetics, A Kinase Anchor Proteins/metabolism, Active Transport, Cell Nucleus, Animals, COS Cells, Cardiomegaly/metabolism, Cell Line, Cercopithecus aethiops, Cyclic AMP-Dependent Protein Kinases/metabolism, Gene Expression Regulation, Guanine Nucleotide Exchange Factors/genetics, Guanine Nucleotide Exchange Factors/metabolism, Heart Ventricles/drug effects, Histone Deacetylases/metabolism, Humans, Models, Biological, Myocytes, Cardiac/drug effects, Myocytes, Cardiac/metabolism, Myogenic Regulatory Factors/metabolism, Phenylephrine/pharmacology, Phosphorylation, Protein Kinase C/metabolism, Proto-Oncogene Proteins/genetics, Proto-Oncogene Proteins/metabolism, RNA Interference, Rats, Signal Transduction, Heart Ventricles, A Kinase Anchor Proteins, Cardiomegaly, Biology, Histone Deacetylases, Article, Minor Histocompatibility Antigens, Phenylephrine, Proto-Oncogene Proteins, Chlorocebus aethiops, Guanine Nucleotide Exchange Factors, Myocytes, Cardiac, Kinase activity, Nuclear export signal, Molecular Biology, Protein Kinase C, Protein kinase C, Regulation of gene expression, Histone deacetylase 5, MEF2 Transcription Factors, Cell Biology, Cyclic AMP-Dependent Protein Kinases, Molecular biology, Cell biology, 14-3-3 Proteins, Myogenic Regulatory Factors, Histone deacetylase, Signal transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784529f321a20f89764ff93eefc37bb5Test

المؤلفون: Didier Trouche, Raphael Herrera, Claude Sardet, Stéphane Emiliani, Laurent Le Cam, Jolanta Polanowska, Eric Fabbrizio

المساهمون: NXP Semiconductors, Laboratoire de biologie moléculaire eucaryote (LBME), Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

المصدر: Oncogene
Oncogene, Nature Publishing Group, 2001, 20 (31), pp.4115--27. ⟨10.1038/sj.onc.1204514⟩

مصطلحات موضوعية: Cancer Research, Cyclin E, Cyclin D, Cyclin A, Molecular Sequence Data, Repressor, Down-Regulation, Mitosis, Cell Cycle Proteins, Chromatography, Affinity, Histone Deacetylases, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, E2F, Promoter Regions, Genetic, Molecular Biology, 030304 developmental biology, Affinity Cyclin E/*genetics Dna *DNA-Binding Proteins *Down-Regulation E2F Transcription Factors Histone Deacetylases/metabolism Humans K562 Cells Mitosis/*genetics Molecular Sequence Data Promoter Regions (Genetics) Repressor Proteins/isolation & purification/metabolism Transcription Factors/metabolism, 0303 health sciences, biology, Cell Cycle, DNA, Cell cycle, Molecular biology, Cell biology, E2F Transcription Factors, DNA-Binding Proteins, Repressor Proteins, 030220 oncology & carcinogenesis, biology.protein, Histone deacetylase activity, biological phenomena, cell phenomena, and immunity, Carrier Proteins Cell Cycle *Cell Cycle Proteins Chromatography, Carrier Proteins, K562 Cells, Cyclin A2, Retinoblastoma-Binding Protein 1, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3c83622b8f0535894356764bf2a4b6dTest
https://pubmed.ncbi.nlm.nih.gov/11464278Test