نتائج البحث - "TCGA, The Cancer Genome Atlas"

1

Prognostic alternative mRNA splicing signatures and associated splicing factors in acute myeloid leukemia

المؤلفون: Kankan Wang, Wei Zhang, Peng Jin, Junmin Li, Yun Tan

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 447-457 (2020)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, RBSURV, robust likelihood-based survival modeling, European LeukemiaNet, Exon, 0302 clinical medicine, hemic and lymphatic diseases, Gene expression, A5SS, Alternative 5′ splice site, AS, Alternative splicing, Myeloid leukemia, Prognosis, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, MXE, Mutually exclusive exons, Leukemia, Myeloid, Acute, 030220 oncology & carcinogenesis, RNA splicing, PSI, Percent spliced in, RNA Splicing Factors, Original article, medicine.medical_specialty, SE, Skipped exon, A3SS, Alternative 3′ splice site, ROC, Receiver operating characteristic, lcsh:RC254-282, HR, Hazard ratio, OS, overall survival, RI, Retained intron, 03 medical and health sciences, Splicing factor, CRISPR, Clustered regularly interspaced short palindromic repeats, Internal medicine, Biomarkers, Tumor, medicine, Humans, RBM39, RNA Binding Motif Protein 39, RNA, Messenger, SETD5, SET Domain Containing 5, Acute myeloid leukemia, business.industry, Mechanism (biology), Gene Expression Profiling, Alternative splicing, AUC, Area under the curve, 030104 developmental biology, ELN, European Leukemia Net, AML, Acute myeloid leukemia, TCGA, The Cancer Genome Atlas, Transcriptome, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1277e66e4646bc171b7371c6de2a9dd9Test
https://doi.org/10.1016/j.neo.2020.06.004Test

2

MCM2, MCM4, and MCM6 in Breast Cancer: Clinical Utility in Diagnosis and Prognosis

المؤلفون: Einas Yousef, Louis Gaboury, Muhammad Tahir, Marianne Samir Makboul Issac

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 10, Pp 1015-1035 (2019)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, %, percentage score, ER, estrogen receptor, Vis.Tis.S., Visiomorph Tissuemorph score, Estrogen receptor, Gene Expression, Disease, Kaplan-Meier Estimate, 0302 clinical medicine, MCM, Minichromosome Maintenance, HER2, human epidermal growth factor receptor 2, Tissue microarray, biology, Prognosis, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, DP, digital pathology, Drug development, 030220 oncology & carcinogenesis, Disease Progression, IHS, Immunohistochemical score, Female, IHC, immunohistochemistry, medicine.medical_specialty, Original article, In silico, Breast Neoplasms, lcsh:RC254-282, 03 medical and health sciences, Breast cancer, Internal medicine, medicine, Biomarkers, Tumor, TMA, tissue microarray, Humans, FFPE, formalin-fixed, paraffin-embedded, Neoplasm Staging, business.industry, MCM6, Gene Expression Profiling, Computational Biology, Minichromosome Maintenance Complex Component 2, medicine.disease, Survival Analysis, Minichromosome Maintenance Complex Component 4, 030104 developmental biology, Ki-67 Antigen, SBR-EE, Scarff-Bloom-Richardson-Elston-Ellis, biology.protein, TCGA, The Cancer Genome Atlas, Neoplasm Grading, HPS, hematoxylinphloxine saffron, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542355ea565d70c766ba7599ccc806abTest
http://www.sciencedirect.com/science/article/pii/S1476558619301575Test

3

Deep learning features from diffusion tensor imaging improve glioma stratification and identify risk groups with distinct molecular pathway activities

المؤلفون: Xiangxiang Wang, Tianqing Ding, Wencai Li, Xuanke Hong, Yinsheng Chen, Li Wang, Wenchao Duan, Dongling Pei, Chen Sun, Jing Yan, Shenghai Zhang, Weiwei Wang, Zhen-Yu Zhang, Yunbo Zhan, Zhicheng Li, Zhen Liu, Jingliang Cheng, Yu Guo, Xianzhi Liu, Lei Liu, Yuanshen Zhao, Wenqing Wang, Haibiao Zhao, Xiaofei Lv, Qiuchang Sun, Tao Sun

المصدر: EBioMedicine
EBioMedicine, Vol 72, Iss, Pp 103583-(2021)

مصطلحات موضوعية: Oncology, Male, AIC, Akaike information criterion, Medicine (General), CNN, convolutional neural networks, DEGs, differentially expressing genes, GSVA, gene set variation analysis, Cohort Studies, Risk Factors, M,D, mean diffusivity, FA, fractional anisotropy, NBTSC, neuron-to-brain tumor synaptic communication, Glutamate secretion, Brain Neoplasms, General Medicine, Glioma, Middle Aged, Prognosis, RD, radial diffusivity, Diffusion tensor imaging, Cohort, Medicine, Female, DLS, deep learning signature, AD, axial diffusivity, Signal Transduction, Research Paper, Adult, TCIA, The Cancer Imaging Archive, medicine.medical_specialty, Adolescent, FDR, false discovery rate, Radiogenomics, CAM, Class activation map, KEGG, Kyoto Encyclopedia of Genes and Genomes, General Biochemistry, Genetics and Molecular Biology, WHO, World Health Organization, Young Adult, R5-920, Deep Learning, Internal medicine, Fractional anisotropy, GO, Gene Ontology, medicine, Humans, KEGG, Aged, LGG, lower-grade gliomas, business.industry, GSA, Genome Sequence Archive, technology, industry, and agriculture, RNA-seq, RNA sequencing, Nomogram, medicine.disease, HR, hazard ratio, NRI, net reclassification improvement, CI, confidence interval, CGGA, China Cancer Genome Atlas, GBM, glioblastoma, TCGA, The Cancer Genome Atlas, DTI, diffusion tensor imaging, business, Diffusion MRI, Pathway

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9b054c5ef9229827f3e793a4fae647Test
https://pubmed.ncbi.nlm.nih.gov/34563923Test

4

Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis

المؤلفون: Yanqing Gong, Liqun Zhou, Jianrong Zheng, Shuyuan Guo, Anbang He, Jieshan Chi, Xinliang Zhong, Yonghao Zhan, Zhicong Chen, Xuesong Li

المصدر: EBioMedicine

مصطلحات موضوعية: 95%CI, 95% Confidence interval, 0301 basic medicine, Oncology, ROC curve, receiver operating characteristic curve, NMIBC, non-muscle-invasive bladder cancer, Urologic cancer, T, size or direct extent of the primary tumour, TRIPOD, Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis, TCGA-PRAD, prostate adenocarcinoma in TCGA chort, Metastasis, TCGA-BLCA, bladder cancer in TCGA chort, Prostate cancer, 0302 clinical medicine, miRNA, microRNA, FFPE, formalin fixed paraffin-embedded, Medicine, CHN, Chinese, GEO, Gene Expression Omnibus, TCGA-KICH, kidney chromophobe carcinoma in TCGA chort, DM, distant metastasis, TCGA-KIRP, kidney papillary cell carcinoma in TCGA chort, Hazard ratio, OR, odds ratios, qRT-PCR, quantitative real-time polymerase chain reaction, REMARK, Reporting Recommendations for Tumour Marker Prognostic Studies, General Medicine, G, histology grade, Prognosis, BRISQ, Biospecimen Reporting for Improved Study Quality, AT, advanced T-stage, Prostate-specific antigen, 030220 oncology & carcinogenesis, miRNAs, HG, higher histologic grade, qPCR, quantitative polymerase chain reaction, RFS, relapse free survival, Research Paper, LNM, lymph nodes metastasis, Stage, TNM stage, ISH, in-situ hybridization, miRNA panel, Urologic Neoplasms, medicine.medical_specialty, BCa, bladder cancer, PCa, prostate cancer, Gleason, gleason score, WHO, World Health Organization, General Biochemistry, Genetics and Molecular Biology, OS, overall survival, 03 medical and health sciences, Bioinformatics analysis, TCGA-KIRC, kidney clear cell carcinoma in TCGA chort, Internal medicine, Humans, Progression-free survival, IQR, interquartile range, non-CHN, Non-Chinese, Bladder cancer, BCR-FS, biochemical recurrence free survival, SE, standard error, CSS, cancer/disease specific survival, business.industry, AS, advanced TNM stage, KCa, kidney cancer, Biomarker, Odds ratio, medicine.disease, PRISMA, Preferred Reporting Items for Systematic Review and Meta-analysis, DFS, disease free survival, MicroRNAs, PSA, prostate specific antigen, 030104 developmental biology, NOS, Newcastle-Ottawa quality assessment scale, AUC, the area under the curve, HR, Hazard Ratio, PFS, progression free survival, RNA, ribonucleic acid, TCGA, The Cancer Genome Atlas, business, Kidney cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32918bcc0de69c7c90eba25335276a77Test
https://doi.org/10.1016/j.ebiom.2018.07.014Test

5

Clinically applicable 53-Gene prognostic assay predicts chemotherapy benefit in gastric cancer: A multicenter study

المؤلفون: Yankai Xia, Jian-Hua Mao, Linghong Liao, Haifeng Wang, Feng Tao, Dexi Jin, Bo Hang, Pin Wang, Wenhuan Li, Chengfei Jiang, Shuting Zhai, Guofu Chen, Xiujun Cai, Bin Li, Xianfa Wang, Linghua Zhu

المصدر: EBioMedicine, Vol 61, Iss, Pp 103023-(2020)
EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, MFI, median fluorescence intensity, medicine.medical_treatment, lcsh:Medicine, Kaplan-Meier Estimate, 0302 clinical medicine, FOLFOX, Databases, Genetic, Antineoplastic Combined Chemotherapy Protocols, Gene prognostic signature, Overall survival, Neoplasm Metastasis, Cancer, screening and diagnosis, lcsh:R5-920, Tumor, Hazard ratio, General Medicine, Prognosis, SX, Shaoxing People's Hospital, Gene Expression Regulation, Neoplastic, Detection, Real-time polymerase chain reaction, Treatment Outcome, 5.1 Pharmaceuticals, A multigene expression assay, 030220 oncology & carcinogenesis, Cohort, Public Health and Health Services, K-M, Kaplan-Meier, Female, Development of treatments and therapeutic interventions, lcsh:Medicine (General), medicine.drug, Research Paper, Biotechnology, 4.2 Evaluation of markers and technologies, medicine.medical_specialty, RT-PCR, reverse transcription-polymerase chain reaction, Clinical Sciences, FOLFOX regimen, General Biochemistry, Genetics and Molecular Biology, OS, overall survival, 03 medical and health sciences, Databases, Genetic, Stomach Neoplasms, Internal medicine, medicine, Biomarkers, Tumor, Genetics, Humans, Chemotherapy, Genetic Testing, Neoplasm Staging, Proportional Hazards Models, Neoplastic, SRRS, Sir Run Run Shaw Hospital, Proportional hazards model, business.industry, Gene Expression Profiling, Human Genome, lcsh:R, medicine.disease, DT, Nanjing Drum Tower Hospital, HR, hazard ratio, Confidence interval, 4.1 Discovery and preclinical testing of markers and technologies, CI, confidence interval, 030104 developmental biology, Good Health and Well Being, Gene Expression Regulation, TCGA, The Cancer Genome Atlas, FOLFOX, leucovorin, fluorouracil, and oxaliplatin, Neoplasm Grading, business, Transcriptome, Gastric cancer, Biomarkers, FFPE, Formalin fixed paraffin-embedded

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9045f565943c137c83b9d0c8e4adddcTest
http://www.sciencedirect.com/science/article/pii/S2352396420303996Test

6

Independent validation of early-stage non-small cell lung cancer prognostic scores incorporating epigenetic and transcriptional biomarkers with gene-gene interactions and main effects

المصدر: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Chest

مصطلحات موضوعية: Oncology, Male, Lung Neoplasms, Critical Care and Intensive Care Medicine, Epigenesis, Genetic, AUC, area under the receiver operating characteristic curve, SIS, sure independence screening, 0302 clinical medicine, Non-small cell lung cancer, Carcinoma, Non-Small-Cell Lung, 030212 general & internal medicine, GEO, Gene Expression Omnibus, KEGG, Kyoto Encyclopedia of Genes and Genomes, Original Research, education.field_of_study, Hazard ratio, Middle Aged, early stage, LUAD, lung adenocarcinoma, Prognosis, prognostic score, Prognostic score, DNA methylation, Disease Progression, Biomarker (medicine), Female, Cardiology and Cardiovascular Medicine, Cindex, concordance index, G×G, gene-gene interactions, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Interaction, TCGA, the Cancer Genome Atlas, Population, interaction, 03 medical and health sciences, Internal medicine, NSCLC, non-small cell lung cancer, medicine, ISIS, iterative sure independence screening, Biomarkers, Tumor, Humans, Epigenetics, KEGG, education, Lung cancer, non-small cell lung cancer, Aged, Neoplasm Staging, Receiver operating characteristic, MGH, Massachusetts General Hospital, business.industry, Early stage, CPTAC, Clinical Proteomic Tumor Analysis Consortium, LUSC, lung squamous cell carcinoma, Epistasis, Genetic, DNA Methylation, medicine.disease, Multiomics, HR, hazard ratio, Survival Analysis, ROC, receiver operating characteristic, QC, quality control, 030228 respiratory system, business, multiomics

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c117fff2ce0d616406ee5b2896746360Test
http://hdl.handle.net/10852/81002Test

7

DAGM: A novel modelling framework to assess the risk of HER2-negative breast cancer based on germline rare coding mutations

المصدر: EBioMedicine, Vol 69, Iss, Pp 103446-(2021)
EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, Oncology, Medicine (General), Receptor, ErbB-2, SVM, Support Vector Machine, WES, whole-exome sequencing, Germline, AUC, area under the receiver operating characteristic curve, 0302 clinical medicine, skin and connective tissue diseases, Exome sequencing, Triple-negative breast cancer, Risk assessment, Aged, 80 and over, Framingham Risk Score, General Medicine, Middle Aged, PR, Progesterone receptor, PBMC, peripheral blood mononuclear cells, RCM, rare coding mutations, 030220 oncology & carcinogenesis, PRS, polygenic risk score, Medicine, Female, Algorithms, Signal Transduction, Research Paper, Adult, medicine.medical_specialty, PCC, Pearson correlation coefficients, Breast Neoplasms, General Biochemistry, Genetics and Molecular Biology, Activity profiles of signalling pathways (APSP), 03 medical and health sciences, R5-920, Germline mutation, Breast cancer, Germline rare coding mutations, Internal medicine, Immune suppression, Damage assessment of genomic mutations (DAGM), medicine, Humans, Genetic Predisposition to Disease, Genetic Testing, CCLE, Cancer Cell Line Encyclopedia, DAGM: damage assessment framework of genomic mutations, Germ-Line Mutation, Aged, business.industry, ER, Estrogen receptor, GDF: global driving force, TNBC, Triple-negative breast cancer, medicine.disease, HER2-negative breast cancer, 030104 developmental biology, HER2 signalling pathway, TCGA, The Cancer Genome Atlas, HER2, human epidermal growth factor 2, GSEA, Gene Set Enrichment Analysis, GWAS: genome-wide association study, Transcriptome, business, Coding (social sciences)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17dbee0e40b9ca491c8a758672b4d7d8Test
https://doi.org/10.1016/j.ebiom.2021.103446Test

8

Combined identification of three miRNAs in serum as effective diagnostic biomarkers for HNSCC

المؤلفون: Qi Zhao, Yanyan Jiang, Zhaoyan Yu, Cameron S. Fletcher, Dongsheng Zhang, Chao Liu, Shengyun Huang, Zhiwei Sun

المصدر: EBioMedicine
EBioMedicine, Vol 50, Iss, Pp 135-143 (2019)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Support Vector Machine, Research paper, Colorectal cancer, lcsh:Medicine, LSCC, laryngeal squamous cell carcinomas, SVM, Support Vector Machine, Disease, Kaplan-Meier Estimate, Microrna, RPM, reads per million miRNAs mapped, 0302 clinical medicine, Diagnosis, lcsh:R5-920, General Medicine, Middle Aged, Prognosis, RBF, radial basis function, 030220 oncology & carcinogenesis, Area Under Curve, embryonic structures, AATK, apoptosis-associated tyrosine kinase, CRC, colorectal cancer, Biomarker (medicine), Female, lcsh:Medicine (General), Databases, Nucleic Acid, Adult, NPC, nasopharyngeal carcinoma, medicine.medical_specialty, ROC, Receiver operating characteristic, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Internal medicine, microRNA, HNSCC, Head and neck squamous cell carcinoma, medicine, Biomarkers, Tumor, Humans, AUC, Area Under the Curve, OSCC, oral squamous cell carcinoma, Survival analysis, Aged, Neoplasm Staging, Proportional Hazards Models, Receiver operating characteristic, business.industry, Squamous Cell Carcinoma of Head and Neck, Gene Expression Profiling, lcsh:R, Computational Biology, Reproducibility of Results, Head and neck squamous cell carcinoma, Biomarker, medicine.disease, Head and neck squamous-cell carcinoma, miRNAs, MicroRNAs, body regions, MicroRNAs, 030104 developmental biology, Nasopharyngeal carcinoma, ROC Curve, TCGA, The Cancer Genome Atlas, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9477f1daf23f14153a180e8ae81d74Test
https://pubmed.ncbi.nlm.nih.gov/31780396Test

9

Age-Associated Proteomic Signatures and Potential Clinically Actionable Targets of Colorectal Cancer

المؤلفون: Lunzhi Dai, Yang Shu, Yanqiu Gong, Yuan Li, Heng Xu, Tian Wang, Hai-Ning Chen, Li Gao, Yu Liu, Zhigui Li, Zong-Guang Zhou

المصدر: Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Male, Proteomics, Oncology, Aging, Telomerase, Colorectal cancer, Biochemistry, Analytical Chemistry, Metastasis, GSEA, gene set enrichment analysis, Cellular Apoptosis Susceptibility Protein, PSEN1, late-onset colorectal cancer, tRNA Methyltransferases, young-onset colorectal cancer, 0303 health sciences, Gene knockdown, Incidence (epidemiology), 030302 biochemistry & molecular biology, Nuclear Proteins, therapeutic target, Middle Aged, Ribonucleoproteins, Small Nuclear, Y, young, M, middle-aged, age-associated biomarkers, CRC, colorectal cancer, Immunohistochemistry, Female, O, aged, Colorectal Neoplasms, Adult, medicine.medical_specialty, FDR, false discovery rate, IHC, immunohistochemical, OS, overall survival, 03 medical and health sciences, Receptors, GABA, Cell Line, Tumor, Internal medicine, CDC2 Protein Kinase, Presenilin-1, medicine, Humans, Molecular Biology, 030304 developmental biology, Proteomic Profiling, business.industry, Research, TMT, tandem mass tag, medicine.disease, digestive system diseases, Repressor Proteins, TCGA, The Cancer Genome Atlas, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1093c6ba5091d2902d34be74ed39c4cbTest
https://doi.org/10.1016/j.mcpro.2021.100115Test

10

Colorectal Adenocarcinoma, Not Just One Disease

المؤلفون: Matthew D. Stachler

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 8, iss 2

مصطلحات موضوعية: Oncology, Epigenomics, Male, RPMM, recursively partitioned mixed model, Disease, CHD, Chromodomain Helicase DNA-Binding, Cohort Studies, Epigenome, Colorectal adenocarcinoma, RBWH, Royal Brisbane and Women’s Hospital, Original Research, Gastroenterology, Age Factors, PRC2, Polycomb Repressive Complex-2, CMS, consensus molecular subtyping, MSI, microsatellite instability, Middle Aged, NCG, Network of Cancer Genes, mRNA, messenger RNA, Gene Expression Regulation, Neoplastic, Editorial, CGI, CpG Island, SUZ12, Supressor Of Zeste 12, DNA methylation, Adenocarcinoma, Epigenetics, DMP, differentially methylated probes, Female, SWI/SNF, SWItch/Sucrose Non-Fermentable, Colorectal Neoplasms, Cohort study, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, MEDLINE, BRAF, Proto-Oncogene Proteins p21(ras), Internal medicine, medicine, KRAS, Humans, neoplasms, Aged, Colorectal Cancer, Hepatology, CIMP, business.industry, Sequence Analysis, RNA, FDR, false-discovery rate, Oncogenes, DNA Methylation, medicine.disease, digestive system diseases, hES, human embryonic stem, CIMP, CpG island methylator phenotype, Mutation, TCGA, The Cancer Genome Atlas, CpG Islands, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186f76e85935ebc574906565909230abTest
http://europepmc.org/articles/PMC6717931Test

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