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1
المصدر: Nucleic Acids Research. 50(11):6102-6115
مصطلحات موضوعية: glutathione, heat shock transcription factor, heat shock transcription factor 1, heat shock transcription factor 2, menadione, RNA polymerase II, transcription factor Nrf2, unclassified drug, DNA binding protein, heat shock protein, Article, Cacybp gene, controlled study, differential expression analysis, down regulation, enhancer region, gene, gene activation, gene expression, genetic transcription, heat stress, Hs 578T cell line, human, human cell, immunofluorescence, oxidation reduction state, oxidative stress, promoter region, temperature, transcription initiation, upregulation, Western blotting, genetics, heat shock response, metabolism, DNA-Binding Proteins, Heat Shock Transcription Factors, Heat-Shock Proteins, Heat-Shock Response
وصف الملف: print
الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-326800Test
https://doi.org/10.1093/nar/gkac493Test -
2دورية أكاديمية
المصدر: Food and Chemical Toxicology ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122617192&doi=10.1016%2fj.fct.2022.112813&partnerID=40&md5=9d6eafe0080f5e91dc6c5cc38fd99b31Test
مصطلحات موضوعية: glutathione, glutathione disulfide, hydrogen peroxide, hydroxymethylglutaryl coenzyme A reductase kinase, kelch like ECH associated protein 1, malonaldehyde, reactive oxygen metabolite, superoxide dismutase, transcription factor Nrf2, xanthohumol, flavonoid, propiophenone derivative, animal experiment, animal model, animal tissue, apoptosis, Article, cell damage, controlled study, cytotoxicity, diabetic wound, enzyme activation, HaCat cell line, histopathology, human, human cell, immunofluorescence, immunoprecipitation, in vitro study, MTT assay
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3دورية أكاديمية
المساهمون: DEPT OF ORTHOPAEDIC SURGERY
المصدر: Unpaywall 20201031
مصطلحات موضوعية: caspase 3, caspase 8, caspase 9, esculetin, immunoglobulin enhancer binding protein, kelch like ECH associated protein 1, reactive oxygen metabolite, transcription factor Nrf2, transcription factor RelA, antineoplastic agent, antioxidant, caspase, protein binding, umbelliferone derivative, antiproliferative activity, apoptosis, Article, cancer inhibition, controlled study, drug cytotoxicity, drug protein binding, G1 phase cell cycle checkpoint, gene expression, human, human cell, mitochondrion, molecular docking, pancreas cancer, pancreatic cancer cell line, protein protein interaction
العلاقة: Arora, R, Sawney, S, Saini, V, Steffi, C, Tiwari, M, Saluja, D (2016). Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1. Molecular Cancer 15 (1) : 64. ScholarBank@NUS Repository. https://doi.org/10.1186/s12943-016-0550-2Test; https://scholarbank.nus.edu.sg/handle/10635/181336Test
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4دورية أكاديمية
المؤلفون: Hu, Q, Khanna, P, Ee Wong, B.S, Heng, Z.S.L, Subhramanyam, C.S, Thanga, L.Z, Tan, S.W.S, Baeg, G.H
المساهمون: ANATOMY, DUKE-NUS MEDICAL SCHOOL
المصدر: Unpaywall 20200831
مصطلحات موضوعية: alpha [amino(4 aminophenylthio)methylene] 2 (trifluoromethyl)phenylacetonitrile, antioxidant, mitogen activated protein kinase, mitogen activated protein kinase 1, mitogen activated protein kinase 3, paraquat, reactive oxygen metabolite, transcription factor Nrf2, Article, cell level, cell structure, controlled study, embryo, embryonic stem cell, gene, gene expression, GFRA1 gene, HOXA1 gene, human, human cell, immunocytochemistry, NANOG gene, NCAM gene, nerve cell differentiation, neurite, NEUROD1 gene, OCT4 gene, oxidative stress, PAX6 gene, polymerase chain reaction
العلاقة: Hu, Q, Khanna, P, Ee Wong, B.S, Heng, Z.S.L, Subhramanyam, C.S, Thanga, L.Z, Tan, S.W.S, Baeg, G.H (2018). Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation. Oncotarget 9 (3) : 4223-4238. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.23786Test; https://scholarbank.nus.edu.sg/handle/10635/174366Test
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5دورية أكاديمية
المؤلفون: Wen Wong D.P., Ng M.Y., Leung J.Y., Boh B.K., Lim E.C., Tan S.H., Lim S., Seah W.H., Hu C.Z., Ho B.C., Ng D.H.P., Hagen T.
المساهمون: DUKE-NUS MEDICAL SCHOOL, DEPT OF BIOCHEMISTRY, OFFICE OF SAFETY, HEALTH AND ENVIRONMENT
المصدر: Unpaywall 20200320
مصطلحات موضوعية: andrographolide, cullin, cullin 3, kelch like ECH associated protein 1, protein RBX1, RING finger protein, sulforaphane, transcription factor Nrf2, unclassified drug, carrier protein, CUL3 protein, human, diterpene, KEAP1 protein, NFE2L2 protein, plant extract, protein binding, RBX1 protein, Article, binding affinity, Calymperes erosum, Campylopus serratus, densitometry, Dicranopteris linearis, endophyte, enzyme activity, fern, human cell, moss, nonhuman
العلاقة: Wen Wong D.P., Ng M.Y., Leung J.Y., Boh B.K., Lim E.C., Tan S.H., Lim S., Seah W.H., Hu C.Z., Ho B.C., Ng D.H.P., Hagen T. (2018). Regulation of the NRF2 transcription factor by andrographolide and organic extracts from plant endophytes. PLoS ONE 13 (10) : e0204853. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0204853Test; https://scholarbank.nus.edu.sg/handle/10635/165895Test
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6Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
المؤلفون: Mirjam M. Schaap, E. van Someren, Peter C. J. Schmeits, Peter J.M. Hendriksen, M. Luijten, Ad A. C. M. Peijnenburg, H. van Loveren, André Boorsma
المساهمون: Promovendi ODB, Gezondheidsvoorlichting, Toxicogenomics, GezondheidsRisico Analyse en Toxicologie, RS: GROW - Oncology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy
المصدر: Archives of Toxicology, 12, 89, 2325-2337
Archives of Toxicology, 89(12), 2325-2337
Archives of Toxicology 89 (2015) 12
Archives of Toxicology, 89(12), 2325-2337. Springerمصطلحات موضوعية: Male, Interspecies comparison, Mouse, Novel Foods & Agrochains, Health, Toxicology and Mutagenesis, RAPID - Risk Analysis for Products in Development, C57BL/6, Biomedical Innovation, Toxicology, Novel Foods & Agroketens, Jurkat cells, Interleukin 2, Unfolded protein response, Jurkat Cells, Mice, In vivo study, Life, Cytotoxic T cell, Immunotoxicity, BU Toxicology, Novel Foods & Agrochains, Splenocytes, Messenger RNA, BU Toxicology, General Medicine, Hep G2 Cells, Cell cycle, Endoplasmic Reticulum Stress, Cell biology, Up-Regulation, CTLL-2, medicine.anatomical_structure, BU Toxicologie, Novel Foods & Agroketens, Cyclosporine, Endoplasmic reticulum stress, Animal cell, Healthy Living, Immunosuppressive Agents, medicine.drug, Human, Cell type, Thymoma, Dpleen cell, BU Toxicologie, T cell, Down-Regulation, Down regulation, Biology, T lymphocyte activation, Cell Line, Thymoma cell line, Transcription factor Nrf2, Cyclosporine A, In vivo, Cell Line, Tumor, Upregulation, medicine, Animals, Humans, Animal experiment, Immune response, Transcriptomics, Protein Unfolding, HepG2 cell line, Cytotoxic T lymphocyte, Gene Expression Profiling, In vitro study, Nonhuman, Jurkat cell line, Mice, Inbred C57BL, Human cell, Cell culture, ELSS - Earth, Life and Social Sciences, Cell cycle regulation, Controlled study, Spleen, T-Lymphocytes, Cytotoxic
وصف الملف: application/octet-stream; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be7ec6d1a47efd3d841c0af6f5ca0a4Test
https://doi.org/10.1007/s00204-014-1365-9Test -
7Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
مصطلحات موضوعية: Interspecies comparison, Male, Mouse, Dpleen cell, C57BL/6, RAPID - Risk Analysis for Products in Development, Biomedical Innovation, Down regulation, Interleukin 2, T lymphocyte activation, Thymoma cell line, Transcription factor Nrf2, Unfolded protein response, Cyclosporine A, In vivo study, Life, Upregulation, Immunotoxicity, Splenocytes, Animal experiment, Life and Social Sciences, Immune response, Transcriptomics, Biology, HepG2 cell line, Cytotoxic T lymphocyte, Messenger RNA, In vitro study, ELSS - Earth, Nonhuman, Jurkat cell line, CTLL-2, Human cell, Endoplasmic reticulum stress, Animal cell, Cell cycle regulation, Controlled study, Healthy Living, Human
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dris___00893::fcc084fa91e986a41972c0c90f60ed45Test
http://resolver.tudelft.nl/uuid:d5268521-be0c-474c-b932-3c9c77e83509Test -
8
المؤلفون: Kirsten A. Baken, Jeroen L. A. Pennings, André Boorsma, Rob J. Vandebriel, Henk Van Loveren, Ralph W.H. Gottschalk, Tessa E. Pronk
المساهمون: TNO Kwaliteit van Leven, Gezondheidsrisico Analyse en Toxicologie, GezondheidsRisico Analyse en Toxicologie, RS: NUTRIM - R4 - Gene-environment interaction
المصدر: Toxicological Sciences, 1, 117, 81-89
Toxicological Sciences, 117(1), 81-89. Oxford University Pressمصطلحات موضوعية: Keratinocytes, 1 chloro 2,4 dinitrobenzene, Biomedical Research, SKIN SENSITIZATION, heat shock protein, Toxicology, glucuronosyltransferase 1A6, thioredoxin 2, sensitization, PATHWAY, ACTIVATION, Gene expression, oxidative stress, phosphogluconate dehydrogenase, interleukin 6 receptor, Oligonucleotide Array Sequence Analysis, glutamate cysteine ligase, CONTACT SENSITIZERS, glucose 6 phosphate dehydrogenase, Chemistry, mitogen activated protein kinase, benzoic acid, In vitro toxicology, article, gene control, salicylic acid methyl ester, Sensitizer, hexane, medicine.anatomical_structure, Biochemistry, SMALL MAF PROTEINS, Irritants, Keratinocyte, eugenol, heme oxygenase 1, ferrochelatase, in vitro study, LINE, disulfiram, 2 propanol, keratinocyte, DENDRITIC CELLS, IL-18 PRODUCTION, transcription factor Nrf2, Cell Line, Gene profiling, collagen type 16, medicine, gene expression profiling, Humans, thioredoxin reductase 1, support vector machine, human, Allergic contact dermatitis, Biology, glutathione reductase, cell viability, thioredoxin reductase 2, human cell culture, IDENTIFICATION, HaCaT, human cell, ferritin, Oxidative Stress Pathway, lactic acid, medicine.disease, ELEMENT-DEPENDENT GENES, cinnamyl alcohol, KEAP1, Gene expression profiling, dodecyl sulfate sodium, nickel sulfate, Irritant oxidative stress, isoeugenol, irritant agent, random forest
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7eb11379b8e8bf29dca184a03a40b3eTest
http://resolver.tudelft.nl/uuid:7f7947b5-4953-4fa1-bbf2-6b32bad5e732Test -
9
المؤلفون: Jac M.M.J.G. Aarts, Yee Y. Lee-Hilz, Hester van der Woude, Ellen Kampman, Ivonne M.C.M. Rietjens, Martijn Vermeulen, Anne-Marie J. F. Boerboom, Birgit I. Bremer, Peter J. van Bladeren
المساهمون: TNO Kwaliteit van Leven
المصدر: Biochemical Pharmacology, 2, 72, 217-226
Biochemical Pharmacology, 72, 217-26
Biochemical Pharmacology, 72(2), 217-226
Biochemical Pharmacology, 72, 2, pp. 217-26
Biochemical Pharmacology 72 (2006) 2مصطلحات موضوعية: Nutrition and Disease, Mouse, Transcription, Genetic, Glutathione transferase, Response element, Screening test, antioxidant activity, Drug structure, Gene Expression, Aetiology, screening and detection [ONCOL 5], Toxicology, Chemoprophylaxis, Biochemistry, Gene, chemistry.chemical_compound, Mice, Transient transfection, Genes, Reporter, Voeding en Ziekte, Gene expression, Determinants in Health and Disease [EBP 1], Gene activation, Reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone), Luteolin, Luciferases, Regulation of gene expression, protein-kinase-c, Structure activity relation, Genetic transcription, Myricetin, Transcription initiation, Validation study, Molecular interaction, Hepa-1c1c7 cells, inducible expression, Reporter gene, Tandem repeat, consensus sequence, Enzyme Induction, transcription factor nrf2, Quercetin, Benzyl isothiocyanate, Animal cell, Plasmids, Tert butylhydroquinone, Biochemie, Gene induction, Biology, chemopreventive agents, Cell Line, Molecular epidemiology [NCEBP 1], nad(p)h-quinone oxidoreductase, Kaempferol, Cancer screening, Structure-Activity Relationship, Drug potency, Antioxidant activity, Translational research [ONCOL 3], Interventional oncology [UMCN 1.5], Cancer cell culture, Animals, Humans, Luciferase, Enhancer, Molecular Biology, Toxicologie, VLAG, DNA Primers, Pharmacology, Flavonoids, Electrophile-responsive element (EpRE), Taxifolin, Hereditary cancer and cancer-related syndromes [ONCOL 1], Base Sequence, subunit gene, Stable luciferase reporter cell lines, colorectal-cancer, Fisetin, Nonhuman, Molecular biology, chemistry, Human cell, detoxify carcinogens, Stereospecificity, Electrophile responsive element mediated gene, Controlled study
وصف الملف: application/octet-stream; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a66c955569a7a1d9dac8a000f68c8feTest
http://resolver.tudelft.nl/uuid:a7d16055-5432-458e-8dc8-db7264681ea0Test -
10دورية أكاديمية
المؤلفون: Labanca, E., De Luca, P., Gueron, G., Paez, A., Moiola, C.P., Massillo, C., Porretti, J., Giudice, J., Zalazar, F., Navone, N., Vazquez, E., De Siervi, A.
مصطلحات موضوعية: BRCA1 protein, cyclin D1, doxorubicin, etoposide, gelatinase B, heme oxygenase 1, hydrogen peroxide, methotrexate, mitoxantrone, transcription factor Nrf2, human, HMOX1 protein, NFE2L2 protein, protein binding, animal cell, animal experiment, animal model, Article, cancer cell, controlled study, DNA damage, enzyme mechanism, homeostasis, human cell, immunofluorescence, in vitro study, in vivo study, male, mouse, nonhuman