دورية أكاديمية
HTLV-1 cosmopolitan and HTLV-2 subtype b among pregnant women of non-endemic areas of Argentina
| العنوان: | HTLV-1 cosmopolitan and HTLV-2 subtype b among pregnant women of non-endemic areas of Argentina |
|---|---|
| المؤلفون: | Berini, Carolina Andrea, Delfino, Cecilia María, Torres, Oscar, García, Gabriela, Espejo, Rogelio, Pianciola, Luis, Juárez, Mirna, Arribere, Graciela, Nadal, Mónica, Eirin, Maria Emilia, Biglione, Mirna Marcela |
| بيانات النشر: | B M J Publishing Group |
| المجموعة: | CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| مصطلحات موضوعية: | Htlv-1, Htlv-2, Pregnancy, Phylogeny, Molecular Epidemiology, Prevention, https://purl.org/becyt/ford/3.3Test, https://purl.org/becyt/ford/3Test |
| الوصف: | OBJECTIVES: The objective of this study was to estimate the prevalence of human T cell lymphotropic virus (HTLV)-1/2, HIV-1, hepatitis B virus (HBV), Trypanosoma cruzi, Treponema pallidum and Toxoplasma gondii infections and to identify the subtypes/subgroups of HTLV-1/2 among pregnant women (PW) from non-endemic provinces of Argentina. METHODS: Methods A total of 2403 samples were screened for HTLV-1/2 and confirmed by western blot and PCR. The long terminal repeat (LTR) of HTLV-1 and HTLV-2 were amplified. Phylogenetic analysis was performed by Neighbour Joining by using molecular evolutionary genetics analysis (MEGA) 4.0. RESULTS: Among a total of 2403 PW studied, 6 (0.25%) tested positive for HTLV-1/2 (3 HTLV-1 (0.12%) and 3 HTLV-2 (0.12%)). The total prevalence when distributed by province was 0.3% (3/804) for Buenos Aires (BA), 0.4% (1/241) for BA surroundings, 0.1% (1/707) for Neuquen and 1.0% (1/95) for Ushuaia. In San Juan, no PW were HTLV-1/2 positive. The prevalence was similar when compared with rates among blood donors of the same areas and years. The phylogenetic analysis classified one sequence as HTLV-1 aA and one as HTLV-2b. The prevalence of HIV-1, HBV, T cruzi, T pallidum and T gondii was 0.6%, 0.2%, 1.4%, 1.2% and 20.9%, respectively. One case of HTLV-1/HIV-1 and one of HTLV-2/HIV-1 co-infection were detected. CONCLUSIONS: HTLV-1/2, which have been associated with different diseases, are circulating among PW of Argentina, even in non-endemic areas. Therefore, testing should be recommended in women who have risk factors for these infections given that the majority of HTLV-1/2 mother to child transmission can be prevented by the avoidance of breast feeding. ; Fil: Berini, Carolina Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina ; Fil: Delfino, ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1368-4973 1472-3263 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/url/http://sti.bmj.com/content/89/4/333.longTest; http://hdl.handle.net/11336/16880Test; Berini, Carolina Andrea; Delfino, Cecilia María; Torres, Oscar; García, Gabriela; Espejo, Rogelio; et al.; HTLV-1 cosmopolitan and HTLV-2 subtype b among pregnant women of non-endemic areas of Argentina; B M J Publishing Group; Sexually Transmitted Infections; 89; 4; 10-2012; 333-335 |
| الإتاحة: | https://doi.org/10.1136/sextrans-2012-050594Test http://hdl.handle.net/11336/16880Test |
| حقوق: | info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by-nc-sa/2.5/arTest/ |
| رقم الانضمام: | edsbas.152D5FF0 |
| قاعدة البيانات: | BASE |
| تدمد: | 13684973 14723263 |
|---|