التفاصيل البيبلوغرافية
| العنوان: |
Long-term health-related quality of life after trauma with and without traumatic brain injury: a prospective cohort study. |
| المؤلفون: |
Kiwanuka, Olivia1,2 (AUTHOR) olivia.kiwanuka@ki.se, Lassarén, Philipp1 (AUTHOR), Thelin, Eric P.1,3 (AUTHOR), Hånell, Anders4 (AUTHOR), Sandblom, Gabriel5 (AUTHOR), Fagerdahl, Ami5 (AUTHOR), Boström, Lennart2,5 (AUTHOR) |
| المصدر: |
Scientific Reports. 2/20/2023, Vol. 13 Issue 1, p1-13. 13p. |
| مصطلحات موضوعية: |
*BRAIN injuries, *QUALITY of life, *MANN Whitney U Test, *COHORT analysis, *LONGITUDINAL method, *LOGISTIC regression analysis, *HELMETS, *HOSPITAL admission & discharge |
| مصطلحات جغرافية: |
STOCKHOLM (Sweden) |
| الشركة/الكيان: |
AMERICAN Society of Anesthesiologists |
| مستخلص: |
To purpose was to assess and compare the health-related quality of life (HRQoL) and risk of depression two years after trauma, between patients with and without traumatic brain injury (TBI) in a mixed Swedish trauma cohort. In this prospective cohort study, TBI and non-TBI trauma patients included in the Swedish Trauma registry 2019 at a level II trauma center in Stockholm, Sweden, were contacted two years after admission. HRQoL was assessed with RAND-36 and EQ-5D-3L, and depression with Montgomery Åsberg depression Rating Scale self-report (MADRS-S). Abbreviated Injury Score (AIS) head was used to grade TBI severity, and American Society of Anesthesiologists (ASA) score was used to assess comorbidities. Data were compared using Chi-squared test, Mann Whitney U test and ordered logistic regression, and Bonferroni correction was applied. A total of 170 of 737 eligible patients were included. TBI was associated with higher scores in 5/8 domains of RAND-36 and 3/5 domains of EQ-5D (p < 0.05). No significant difference in MADRS-S. An AIS (head) of three or higher was associated with lower scores in five domains of RAND-36 and two domains of EQ-5D but not for MADRS-S. An ASA-score of three was associated with lower scores in all domains of both RAND-36 (p < 0.05, except mental health) and EQ-5D (p < 0.001, except anxiety/depression), but not for MADRS-S. In conclusion, patients without TBI reported a lower HRQoL than TBI patients two years after trauma. TBI severity assessed according to AIS (head) was associated with HRQoL, and ASA-score was found to be a predictor of HRQoL, emphasizing the importance of considering pre-injury health status when assessing outcomes in TBI patients. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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