المؤلفون: McNeish, IA, Kondrashova, O, Topp, M, Nesic, K, Lieschke, E, Ho, G-Y, Harrell, MI, Zapparoli, GV, Hadley, A, Holian, R, Boehm, E, Heong, V, Sanij, E, Pearson, RB, Krais, JJ, Johnson, N, McNally, O, Ananda, S, Alsop, K, Hutt, KJ, Kaufmann, SH, Lin, KK, Harding, TC, Traficante, N, DeFazio, A, Bowtell, DD, Swisher, EM, Dobrovic, A, Wakefield, MJ, Scott, CL

المساهمون: Imperial College Healthcare NHS Trust- BRC Funding, Cancer Research UK

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, HOMOLOGOUS RECOMBINATION REPAIR, OLAPARIB MAINTENANCE THERAPY, SPORADIC BREAST-CANCER, POLYMERASE INHIBITORS, POLY(ADP-RIBOSE) POLYMERASE, PLATINUM RESPONSE, SOMATIC MUTATIONS, PROMOTER REGION, FALLOPIAN-TUBE, PHASE-2 TRIAL, Animals, Antineoplastic Agents, BRCA1 Protein, Cell Line, Tumor, Cisplatin, DNA Methylation, Female, Gene Dosage, Humans, Indoles, Kaplan-Meier Estimate, Mice, Inbred NOD, Knockout, SCID, Ovarian Neoplasms

العلاقة: Nature Communications; http://hdl.handle.net/10044/1/61797Test; https://dx.doi.org/10.1038/s41467-018-05564-zTest; RDB01; RG71079

الإتاحة: https://doi.org/10.1038/s41467-018-05564-zTest
http://hdl.handle.net/10044/1/61797Test

المؤلفون: Nesic, K, Wakefield, M, Kondrashova, O, Scott, CL, McNeish, IA

مصطلحات موضوعية: Science & Technology, CANCER SUSCEPTIBILITY GENE, homologous recombination, mutational signatures, HOMOLOGOUS RECOMBINATION REPAIR, 1103 Clinical Sciences, PARP INHIBITOR, SOMATIC MUTATIONS, BRCA1, BRCA2, PROSTATE-CANCER, Oncology, DOUBLE-STRAND BREAK, UNCERTAIN SIGNIFICANCE, copy number signatures, POLY(ADP-RIBOSE) POLYMERASE INHIBITORS, Pathology, EPITHELIAL OVARIAN-CANCER, loss of heterozygosity, next-generation sequencing, TANDEM DUPLICATOR PHENOTYPE, ovarian high-grade serous carcinoma, Life Sciences & Biomedicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______1032::7b00e45a09e04864b009c74cdf1dbcdfTest
http://hdl.handle.net/10044/1/55470Test

المؤلفون: Kondrashova, O, Nguyen, M, Shield-Artin, K, Tinker, AV, Teng, NNH, Harrell, MI, Kuiper, MJ, Ho, G-Y, Barker, H, Jasin, M, Prakash, R, Kass, EM, Sullivan, MR, Brunette, GJ, Bernstein, KA, Coleman, RL, Floquet, A, Friedlander, M, Kichenadasse, G, O'Malley, DM, Oza, A, Sun, J, Robillard, L, Maloney, L, Bowtell, D, Giordano, H, Wakefield, MJ, Kaufmann, SH, Simmons, AD, Harding, TC, Raponi, M, McNeish, IA, Swisher, EM, Lin, KK, Scott, CL

المصدر: 998 ; 984

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Oncology, HOMOLOGOUS RECOMBINATION REPAIR, GERMLINE MUTATIONS, POLYMERASE INHIBITORS, MAINTENANCE THERAPY, MOLECULAR-DYNAMICS, PLATINUM RESPONSE, FALLOPIAN-TUBE, PHASE-2 TRIAL, DNA-DAMAGE, CANCER, AOCS Study Group

العلاقة: Cancer Discovery; http://hdl.handle.net/10044/1/54678Test; https://dx.doi.org/10.1158/2159-8290.CD-17-0419Test

الإتاحة: https://doi.org/10.1158/2159-8290.CD-17-0419Test
http://hdl.handle.net/10044/1/54678Test