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العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/SAF2017-83351-R; SAF2017-83351-R/AEI/10.13039/501100011033; Publisher’s version; https://doi.org/10.3390/jcm9061766Test; Sí; Journal of Clinical Medicine 9(6): 1766 (2020); http://hdl.handle.net/10261/215680Test

الإتاحة: https://doi.org/10.3390/jcm9061766Test
http://hdl.handle.net/10261/215680Test

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النص الكامل

4

دورية أكاديمية

Topically Applied Etamsylate: A New Orphan Drug for HHT-Derived Epistaxis (Antiangiogenesis through FGF Pathway Inhibition)

المؤلفون: Virginia Albiñana, Guillermo Giménez-Gallego, Angela García-Mato, Patricia Palacios, Lucia Recio-Poveda, Angel-M Cuesta, José-Luis Patier, Luisa-María Botella

المصدر: TH Open, Vol 03, Iss 03, Pp e230-e243 (2019)

مصطلحات موضوعية: hht, endoglin, alk1, antiangiogenesis, etamsylate, epistaxis, fgf pathway, tgf-β signaling pathway, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2512-9465Test

الوصول الحر: https://doaj.org/article/02fb504621504e31997fc759d8991017Test

View record in DOAJ

النص الكامل

5

دورية أكاديمية

Topically applied etamsylate: a new orphan drugfor HHT-derived epistaxis (antiangiogenesisthrough FGF pathway inhibition)

المؤلفون: Albiñana, Virginia, Giménez-Gallego, Guillermo, García-Mato, Ángela, Palacios, Patricia, Recio-Poveda, Lucía, Cuesta, Ángel M., Patier, José-Luis, Botella, Luisa María

المساهمون: Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Instituto de Salud Carlos III, Asociación HHT Española, Albiñana, Virginia, Botella, Luisa María

مصطلحات موضوعية: HHT, Endoglin, ALK1, Antiangiogenesis, Etamsylate, Epistaxis, FGF pathway, TGF-β signaling pathway

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2014-52374-R; MICIU/ICTI2017-2020/SAF2017-83351; Publisher's version; https://doi.org/10.1055/s-0039-1693710Test; Sí; TH Open 03 (03) :e230–e243 (2019); http://hdl.handle.net/10261/187212Test; http://dx.doi.org/10.13039/501100003329Test; http://dx.doi.org/10.13039/501100004587Test

الإتاحة: https://doi.org/10.1055/s-0039-1693710Test
https://doi.org/10.13039/501100003329Test
https://doi.org/10.13039/501100004587Test
http://hdl.handle.net/10261/187212Test

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النص الكامل

6

دورية أكاديمية

Endoglin and alk1 as therapeutic targets for hereditary hemorrhagic telangiectasia

المؤلفون: Ruiz-Llorente, Lidia, Gallardo-Vara, Eunate, Rossi, Elisa, Smadja, David M., Botella, Luisa María, Bernabéu, Carmelo

المساهمون: Instituto de Salud Carlos III, Ministerio de Economía, Industria y Competitividad (España)

مصطلحات موضوعية: HHT, Endoglin, ALK1, Haploinsufficiency, Bleeding, Angiogenesis, AVM, Bevacizumab, Thalidomide

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2013-43421-R; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2014-52374-R; Publisher's version; http://dx.doi.org/10.1080/14728222.2017.1365839Test; Sí; Expert Opin Ther Targets. 21(10):933-947 (2017); http://hdl.handle.net/10261/155101Test; http://dx.doi.org/10.13039/501100004587Test; http://dx.doi.org/10.13039/501100010198Test

الإتاحة: https://doi.org/10.1080/14728222.2017.1365839Test
https://doi.org/10.13039/501100004587Test
https://doi.org/10.13039/501100010198Test
http://hdl.handle.net/10261/155101Test

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7

دورية أكاديمية

Research on potential biomarkers in hereditary hemorrhagic telangiectasia

المؤلفون: Botella, Luisa María, Albiñana, Virginia, Ojeda-Fernández, María Luisa, Recio-Poveda, Lucía, Bernabéu, Carmelo

مصطلحات موضوعية: Biomarkers, HHT, Endoglin, ALK1, miRNA, TGF-b, VEGF, Ang-2

العلاقة: http://dx.doi.orgTest/ 10.3389/fgene.2015.00115; Sí; Frontiers in Genetics 6: 115 (2015); http://hdl.handle.net/10261/114382Test

الإتاحة: https://doi.org/10.3389/fgene.2015.00115Test
http://hdl.handle.net/10261/114382Test

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النص الكامل

8

دورية أكاديمية

Executive summary of the 11th HHT international scientific conference

المؤلفون: Arthur, Helen, Geisthoff, Urban, Gossage, James R., Hughes, Christopher C.W., Lacombe, Pascal, Meek, Mary E., Oh, Paul, Roman, Beth L., Trerotola, Scott O., Velthuis, Sebastiaan, Wooderchak-Donahue, Whitney

المصدر: Neurobiology

مصطلحات موضوعية: ALK1, Arteriovenous malformation, Endoglin, Epistaxis, Hereditary hemorrhagic telangiectasia, HHT

العلاقة: https://scholar.barrowneuro.org/neurobiology/664Test

الإتاحة: https://scholar.barrowneuro.org/neurobiology/664Test

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9

Mutational and phenotypic characterization of hereditary hemorrhagic telangiectasia

المؤلفون: Karyn Megy, Willem H. Ouwehand, Loren Kell, Jonathan Stephens, Kate Downes, Abigail Shurr, Claire L. Shovlin, Ilenia Simeoni, D Patel, Maria E. Bernabeu-Herrero, Micheala A. Aldred, Zoe C. Frazer, Christopher J. Penkett, Luca Jovine, Jennifer Brimley, Isobel G. Turbin, Ernest Turro

المساهمون: Imperial College Trust, Imperial College Healthcare NHS Trust, Imperial College Healthcare NHS Trust - CLRN Funding, Imperial College Healthcare NHS Trust- BRC Funding

المصدر: Blood

مصطلحات موضوعية: 0301 basic medicine, Male, Models, Molecular, Clinical Trials and Observations, Activin Receptors, Type II, DNA Mutational Analysis, ALK1, Biochemistry, Cohort Studies, 0302 clinical medicine, Genotype, Growth Differentiation Factor 2, 1102 Cardiorespiratory Medicine and Haematology, Smad4 Protein, Massive parallel sequencing, medicine.diagnostic_test, Endoglin, GENETIC-VARIATION, High-Throughput Nucleotide Sequencing, TGF-BETA, Hematology, Genomics, GENOTYPE, PREVALENCE, Phenotype, Medical genetics, ARTERIOVENOUS-MALFORMATIONS, Female, Telangiectasia, Hereditary Hemorrhagic, Life Sciences & Biomedicine, medicine.medical_specialty, Heterozygote, Immunology, Context (language use), Computational biology, Biology, HHT, 03 medical and health sciences, Human Phenotype Ontology, Genetic variation, medicine, Humans, Genetic Predisposition to Disease, Genetic Testing, Genetic Association Studies, Genetic testing, Retrospective Studies, Science & Technology, IDENTIFICATION, 1103 Clinical Sciences, Cell Biology, Sequence Analysis, DNA, 030104 developmental biology, Mutation, 1114 Paediatrics and Reproductive Medicine, JUVENILE POLYPOSIS, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67c88ac838f58210b09668375add670Test
https://europepmc.org/articles/PMC7717479Test/

10

دورية أكاديمية

Mutational and phenotypic characterisation of hereditary hemorrhagic telangiectasia

المؤلفون: Shovlin, C, Simeoni, I, Downes, K, Frazer, Z, Megy, K, Bernabeu-Herrero, M, Shurr, A, Brimley, J, Patel, D, Kell, L, Stephens, J, Turbin, I, Aldred, M, Penkett, C, Stirrups, K, Ouwehand, W, Jovine, L, Turro, E

المساهمون: Imperial College Trust, Imperial College Healthcare NHS Trust, Imperial College Healthcare NHS Trust - CLRN Funding, Imperial College Healthcare NHS Trust- BRC Funding

المصدر: 1918 ; 1907

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Hematology, ARTERIOVENOUS-MALFORMATIONS, JUVENILE POLYPOSIS, GENETIC-VARIATION, TGF-BETA, GENOTYPE, ENDOGLIN, HHT, PREVALENCE, ALK1, IDENTIFICATION, 1102 Cardiorespiratory Medicine and Haematology, 1103 Clinical Sciences, 1114 Paediatrics and Reproductive Medicine, Immunology

العلاقة: Blood; http://hdl.handle.net/10044/1/79705Test; N/A; WHCV_P38899; CPG1 CLRN ABF 11110D; WHCV_P44377; RDLRN; RDB02

الإتاحة: https://doi.org/10.1182/blood.2019004560Test
http://hdl.handle.net/10044/1/79705Test

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