المؤلفون: Easton, Douglas F, Pharoah, Paul DP, Antoniou, Antonis C, Tischkowitz, Marc, Tavtigian, Sean V, Nathanson, Katherine L, Devilee, Peter, Meindl, Alfons, Couch, Fergus J, Southey, Melissa, Goldgar, David E, Evans, D Gareth R, Chenevix-Trench, Georgia, Rahman, Nazneen, Robson, Mark, Domchek, Susan M, Foulkes, William D

مصطلحات موضوعية: Breast Neoplasms, Centers for Disease Control and Prevention, U.S, Female, Genes, BRCA1, BRCA2, Genetic Predisposition to Disease, Genetic Testing, Genetic Variation, Genotyping Techniques, Guidelines as Topic, Heterozygote, Humans, Risk, Sequence Analysis, DNA, United States

وصف الملف: application/pdf

العلاقة: https://www.repository.cam.ac.uk/handle/1810/254233Test

الإتاحة: https://www.repository.cam.ac.uk/handle/1810/254233Test

المؤلفون: Foster, C, Watson, M, Eeles, Rosalind, Eccles, Diana, Ashley, Sue, Davidson, R, Mackay, J, Morrison, P J, Hopwood, Penelope, Evans, D Gareth R

المساهمون: Macmillan Research Unit, School of Nursing and Midwifery, University of Southampton, Southampton, UK.

مصطلحات موضوعية: Breast Cancer, Ovarian Cancer, Prostate Cancer, Adult, Breast Neoplasms, Female, Genes, BRCA1, BRCA2, Genetic Predisposition to Disease, Genetic Screening, Great Britain, Heterozygote, Humans, Insurance Selection Bias, Male, Mammography, Ovarian Neoplasms, Ovariectomy, Patient Compliance, Prostatic Neoplasms, Risk Management

العلاقة: Predictive genetic testing for BRCA1/2 in a UK clinical cohort: three-year follow-up. 2007, 96 (5):718-24 Br. J. Cancer; http://hdl.handle.net/10541/71931Test; British Journal of Cancer

الإتاحة: https://doi.org/10.1038/sj.bjc.6603610Test
http://hdl.handle.net/10541/71931Test

المؤلفون: Maurice, Andrew, Evans, D Gareth R, Shenton, Andrew, Ashcroft, Linda, Baildam, Andrew D, Barr, Lester, Byrne, Ged J, Bundred, Nigel J, Boggis, C, Wilson, M, Duffy, Stephen W, Howell, Anthony

المساهمون: Breast Cancer Family History Clinic, Nightingale Centre, Withington Hospital, South Manchester University Hospital Trust, Manchester, UK.

مصطلحات موضوعية: Breast Cancer, Adult, Breast Neoplasms, Early Diagnosis, Female, Genes, BRCA1, BRCA2, Genetic Screening, Heterozygote, Humans, Mammography, Middle Aged, Pedigree, Survival Analysis, Treatment Outcome

العلاقة: Screening younger women with a family history of breast cancer--does early detection improve outcome? 2006, 42 (10):1385-90 Eur. J. Cancer; http://hdl.handle.net/10541/72656Test; European Journal of Cancer

الإتاحة: https://doi.org/10.1016/j.ejca.2006.01.055Test
http://hdl.handle.net/10541/72656Test

المؤلفون: Shanley, Susan, McReynolds, Kate, Ardern-Jones, Audrey, Ahern, Roger, Fernando, Indrajit, Yarnold, John, Evans, D Gareth R, Eccles, Diana, Hodgson, Shirley V, Ashley, Sue, Ashcroft, Linda, Tutt, Andrew, Bancroft, Elizabeth, Short, Susan, Gui, Gerald, Barr, Lester, Baildam, Andrew D, Howell, Anthony, Royle, Gavin, Pierce, Lori, Easton, Douglas, Eeles, Rosalind

المساهمون: Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, UK. Susan.Shanley@rmh.nhs.uk

مصطلحات موضوعية: Breast Cancer, Cancer Staging, Adult, Aged, Breast Neoplasms, Case-Control Studies, Female, Follow-Up Studies, Genes, BRCA1, BRCA2, Germ-Line Mutation, Great Britain, Heterozygote, Humans, Middle Aged, Neoplasm Staging, Radiotherapy, Retrospective Studies, Treatment Outcome

العلاقة: Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing breast radiotherapy in the United Kingdom. 2006, 12 (23):7025-32 Clin. Cancer Res.; http://hdl.handle.net/10541/72595Test; Clinical Cancer Research

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-06-1244Test
http://hdl.handle.net/10541/72595Test

المؤلفون: Watson, M, Foster, C, Eeles, Rosalind, Eccles, D, Ashley, Sue, Davidson, R, Mackay, J, Morrison, P J, Hopwood, Penelope, Evans, D Gareth R

المساهمون: Department of Psychological Medicine, Royal Marsden NHS Foundation Trust, London & Sutton, SM2 5PT, England. Maggie.Watson@rmh.nthames.nhs.uk

مصطلحات موضوعية: Breast Cancer, Ovarian Cancer, Adult, Age Factors, Anxiety, Breast Neoplasms, Cohort Studies, Female, Genes, BRCA1, BRCA2, Genetic Predisposition to Disease, Genetic Screening, Great Britain, Heterozygote, Humans, Insurance Selection Bias, Male, Middle Aged, Mutation, Ovarian Neoplasms, Questionnaires, Risk Management, Sex Factors

العلاقة: Psychosocial impact of breast/ovarian (BRCA1/2) cancer-predictive genetic testing in a UK multi-centre clinical cohort. 2004, 91 (10):1787-94 Br. J. Cancer; http://hdl.handle.net/10541/77858Test; British Journal of Cancer

الإتاحة: https://doi.org/10.1038/sj.bjc.6602207Test
http://hdl.handle.net/10541/77858Test

المؤلفون: Birch, Jillian M, Alston, Robert D, McNally, Richard J Q, Evans, D Gareth R, Kelsey, Anna M, Harris, Martin, Eden, Tim O B, Varley, Jennifer

المساهمون: CRC Paediatric and Familial Cancer Research Group and Department of Pathology, Royal Manchester Children's Hospital, Stancliffe, Hospital Road, Manchester M27 4HA, UK. Jillian.m.birch@man.ac.uk

مصطلحات موضوعية: Tumour Suppressor Protein p53, Adolescent, Adult, Aged, Child, Preschool, Cohort Studies, Family Health, Female, Genetic Predisposition to Disease, Germ-Line Mutation, Heterozygote, Humans, Infant, Li-Fraumeni Syndrome, Male, Middle Aged, Tumor Suppressor Protein p53

العلاقة: Relative frequency and morphology of cancers in carriers of germline TP53 mutations. 2001, 20 (34):4621-8 Oncogene; http://hdl.handle.net/10541/84125Test; Oncogene

الإتاحة: https://doi.org/10.1038/sj.onc.1204621Test
http://hdl.handle.net/10541/84125Test

المؤلفون: Varley, Jennifer, McGown, Gail, Thorncroft, Mary R, White, Gavin R M, Tricker, K J, Kelsey, Anna M, Birch, Jillian M, Evans, D Gareth R

المساهمون: CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Kidney Cancer, Tumour Suppressor Protein p53, Wilms Tumour, Child, Preschool, Exons, Female, Germ-Line Mutation, Heterozygote, Humans, Kidney Neoplasms, Li-Fraumeni Syndrome, Male, Pedigree, Point Mutation, Tumor Suppressor Protein p53, Wilms Tumor

العلاقة: A novel TP53 splicing mutation in a Li-Fraumeni syndrome family: a patient with Wilms' tumour is not a mutation carrier. 1998, 78 (8):1081-3 Br. J. Cancer; 9792154; http://hdl.handle.net/10541/93411Test; British Journal of Cancer

الإتاحة: http://hdl.handle.net/10541/93411Test

المؤلفون: Hoban, Paul R, Cowen, Rachel L, Mitchell, Erika L D, Evans, D Gareth R, Kelly, M, Howard, P J, Heighway, Jim

المساهمون: CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie Hospital (NHS) Trust, Manchester, UK.

مصطلحات موضوعية: Wilms Tumour, Chromosome Fragility, Chromosome Mapping, Chromosomes, Human, Pair 5, Pair 6, Heterozygote, Humans, In Situ Hybridization, Fluorescence, Infant, Male, Translocation, Genetic, Wilms Tumor

العلاقة: Physical localisation of the breakpoints of a constitutional translocation t(5;6)(q21;q21) in a child with bilateral Wilms' tumour. 1997, 34 (4):343-5 J. Med. Genet.; 9138163; http://hdl.handle.net/10541/95488Test; Journal of Medical Genetics

الإتاحة: https://doi.org/10.1136/jmg.34.4.343Test
http://hdl.handle.net/10541/95488Test

المؤلفون: Evans, D Gareth R, Maher, E R, Macleod, R, Davies, D R, Craufurd, D

المساهمون: CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Christie Hospital, Manchester, UK.

مصطلحات موضوعية: Tumour Suppressor Protein p53, Adenomatous Polyposis Coli, Adolescent, Adult, Attitude to Health, Child, Preschool, Female, Genetic Counseling, Genetic Testing, Great Britain, Heterozygote, Humans, Li-Fraumeni Syndrome, Male, Mutation, Neurofibromatosis 2, Tumor Suppressor Protein p53, von Hippel-Lindau Disease

العلاقة: Uptake of genetic testing for cancer predisposition. 1997, 34 (9):746-8 J. Med. Genet.; 9321761; http://hdl.handle.net/10541/95490Test; Journal of Medical Genetics

الإتاحة: https://doi.org/10.1136/jmg.34.9.746Test
http://hdl.handle.net/10541/95490Test

المؤلفون: Varley, Jennifer, Evans, D Gareth R, Birch, Jillian M

المساهمون: CRC Department of Cancer Genetics, Paterson Institute for Cancer Research, Manchester, UK.

مصطلحات موضوعية: Cancer, Tumour Suppressor Protein p53, Animals, Chromosome Deletion, Disease Models, Animal, Germ-Line Mutation, Heterozygote, Humans, Li-Fraumeni Syndrome, Mice, Knockout, Transgenic, Neoplasms, Tumor Suppressor Protein p53

العلاقة: Li-Fraumeni syndrome--a molecular and clinical review. 1997, 76 (1):1-14 Br. J. Cancer; 9218725; http://hdl.handle.net/10541/94953Test; British Journal of Cancer

الإتاحة: http://hdl.handle.net/10541/94953Test