دورية أكاديمية

COVID‐19 rapidly increases MDSCs and prolongs innate immune dysfunctions.

التفاصيل البيبلوغرافية
العنوان: COVID‐19 rapidly increases MDSCs and prolongs innate immune dysfunctions.
المؤلفون: Schrijver, Irene T., Théroude, Charlotte, Antonakos, Nikolaos, Regina, Jean, Le Roy, Didier, Bart, Pierre‐Alexandre, Chiche, Jean‐Daniel, Perreau, Matthieu, Pantaleo, Giuseppe, Calandra, Thierry, Roger, Thierry
المصدر: European Journal of Immunology; Oct2022, Vol. 52 Issue 10, p1676-1679, 4p
مصطلحات موضوعية: COVID-19 pandemic, MYELOID-derived suppressor cells, REGULATORY T cells, POST-acute COVID-19 syndrome, HEPATOCYTE growth factor
مستخلص: Severe COVID-19 patients had higher leukocyte counts and longer hospital stay than moderate COVID-19 patients (Supporting Information Table S1). COVID-19 rapidly increases MDSCs and prolongs innate immune dysfunctions We analyzed polymononuclear-MDSCs (PMN-MDSCs) and monocytic-MDSCs (M-MDSCs), the two main subgroups of MDSCs [1], in 56 COVID-19 patients analyzed at hospitalization and 21 patients analyzed 3 months later. Keywords: COVID-19; Cytokines; Dendritic cells; Monocytes; Myeloid-derived suppressor cells EN COVID-19 Cytokines Dendritic cells Monocytes Myeloid-derived suppressor cells 1676 1679 4 10/13/22 20221001 NES 221001 We used unsupervised immunophenotyping of blood leukocytes and measured cytokine production by innate immune cell exposed to LPS and R848. [Extracted from the article]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:00142980
DOI:10.1002/eji.202249827