المؤلفون: Ruben van Boxtel, Paul J. Coffer, Bruno A. Cardoso, Alice Melão, Milene Costa da Silva, Daniel Dias Ribeiro, Cristina Santos, Ana Elisa Bauer de Camargo Silva, João T. Barata

المصدر: Blood Advances
Blood Advances, 2(17), 2199. The American Society of Hematology

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Cell Survival, T cell, T-cell leukemia, PIM1, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, 03 medical and health sciences, Proto-Oncogene Proteins c-pim-1, Downregulation and upregulation, hemic and lymphatic diseases, STAT5 Transcription Factor, Tumor Cells, Cultured, medicine, Humans, Protein kinase B, Mechanistic target of rapamycin, Cell Proliferation, Lymphoid Neoplasia, biology, Gene Expression Regulation, Leukemic, Chemistry, Interleukin-7, JAK-STAT signaling pathway, Hematology, medicine.disease, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Cancer research, biology.protein

وصف الملف: image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfc9c50e679fc64928c3f77ce3b0ee4Test
https://doi.org/10.1182/bloodadvances.2018021063Test

المؤلفون: Ruben van Boxtel, Ribeiro Daniel, Alice Melão, Ana Elisa Bauer de Camargo Silva, Milene Costa da Silva, Bruno A. Cardoso, João T. Barata, Paul J. Coffer, Cristina Santos

المصدر: Blood. 132:914-914

مصطلحات موضوعية: biology, Cell growth, Immunology, Cyclin A, PIM1, Cell Biology, Hematology, Cell cycle, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, hemic and lymphatic diseases, biology.protein, Cancer research, 030212 general & internal medicine, Signal transduction, Protein kinase B, PI3K/AKT/mTOR pathway

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4afd2d498f79c8bc40fa38c3a3f32a30Test
https://doi.org/10.1182/blood-2018-99-113778Test

المؤلفون: Veerle Fleskens, Cornelieke E.G.M. Pals, S G J M Coenen, Michal Mokry, Bruno A. Cardoso, Janneke G. C. Peeters, Paul J. Coffer, S Huppelschoten, A M van der Leun, João T. Barata, J van Loosdregt

المساهمون: Repositório da Universidade de Lisboa

المصدر: Oncogene, 35, 4141–4148. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, LMO2, Cancer Research, T-Cell Acute Lymphocytic Leukemia Protein 1, Biology, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, 03 medical and health sciences, Proto-Oncogene Proteins, hemic and lymphatic diseases, Basic Helix-Loop-Helix Transcription Factors, Genetics, Journal Article, Humans, Viability assay, Transcription factor, Molecular Biology, Adaptor Proteins, Signal Transducing, Tumor Suppressor Proteins, Cell Cycle, FOXP3, Forkhead Transcription Factors, hemic and immune systems, LIM Domain Proteins, Cell cycle, 030104 developmental biology, Cell culture, Cancer research, TAL1

وصف الملف: image/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3326fdcd34073e6c4c0f567431d70458Test
https://dspace.library.uu.nl/handle/1874/346503Test

المؤلفون: Alice Melão, D Drygin, R Stansfield, Leila R. Martins, João T. Barata, Paulo Lúcio, I Antunes, Paolo Ghia, Maria Gomes da Silva, Maria Teresa Sabrina Bertilaccio, Bruno A. Cardoso

المساهمون: Martins, Lr, Lucio, P, Melao, A, Antunes, I, Cardoso, Ba, Stansfield, R, Bertilaccio, Mt, Ghia, PAOLO PROSPERO, Drygin, D, Silva, Mg, Barata, Jt

المصدر: Leukemia

مصطلحات موضوعية: Cancer Research, animal structures, business.industry, Chronic lymphocytic leukemia, fungi, Antineoplastic Agents, Hematology, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, 3. Good health, Leukemia, Oncology, hemic and lymphatic diseases, Protein kinase CK2, embryonic structures, Immunology, Cancer research, medicine, Humans, Phenazines, Stage (cooking), Naphthyridines, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a974179c485ca940cd280df8cb522970Test

المؤلفون: Hélio Belo, Antonio Almeida, Bruno A. Cardoso, Gabriela Silva

المساهمون: Centro de Estudos de Doenças Crónicas (CEDOC), NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

المصدر: PLoS ONE, Vol 8, Iss 1, p e53766 (2013)
PLoS ONE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: DOWN-REGULATION, Myeloid, Cellular differentiation, lcsh:Medicine, Apoptosis, SUBEROYLANILIDE HYDROXAMIC ACID, Hydroxamic Acids, Hematologic Cancers and Related Disorders, 0302 clinical medicine, hemic and lymphatic diseases, Molecular Cell Biology, Basic Cancer Research, lcsh:Science, CELL LYMPHOMA, Vorinostat, 0303 health sciences, Multidisciplinary, Histone deacetylase inhibitor, Cell Differentiation, Hematology, Cell cycle, CD34(+) CELLS, 3. Good health, Leukemia, Myeloid, Acute, TRANSCRIPTION FACTORS, Haematopoiesis, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Medicine, Epigenetics, Oncology Agents, DNA modification, Histone modification, Research Article, medicine.drug, Acute Myeloid Leukemia, medicine.drug_class, BONE-MARROW, Antineoplastic Agents, HL-60 Cells, Biology, HISTONE DEACETYLASE INHIBITOR, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Leukemias, Genetics, MYELODYSPLASTIC SYNDROMES, medicine, Humans, CANCER-CELLS, 030304 developmental biology, Base Sequence, lcsh:R, Cell Cycle Checkpoints, SP FAMILY, Bone Marrow Failure, GC Rich Sequence, Hematopoiesis, Myelodysplastic Syndromes, Cancer cell, Immunology, Cancer research, lcsh:Q, Gene expression, K562 Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3634afa05575e8173213c1fca722cc70Test
http://europepmc.org/articles/PMC3540071?pdf=renderTest

المؤلفون: Vassiliki A. Boussiotis, Leila R. Martins, Angelo A. Cardoso, Bruno A. Cardoso, João T. Barata, Cristina Santos, Lee M. Nadler

المصدر: Leukemia. 23(1)

مصطلحات موضوعية: Cancer Research, T cell, Biology, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Article, hemic and lymphatic diseases, medicine, Tumor Cells, Cultured, Humans, PI3K/AKT/mTOR pathway, Interleukin 4, Cell Proliferation, Mtor signaling, Cell growth, TOR Serine-Threonine Kinases, RPTOR, hemic and immune systems, Hematology, Cell biology, medicine.anatomical_structure, Oncology, Interleukin-4, Signal transduction, Protein Kinases, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f72855909c8f18c4ecde73660b5fc5Test
https://pubmed.ncbi.nlm.nih.gov/18596736Test