التفاصيل البيبلوغرافية
| العنوان: |
Effect of dexamethasone on coxsackievirus B2-infected rat beating heart cells in culture. |
| المؤلفون: |
Yang, Y. Z., Yuan, W. L., Guo, Q., Gong, Z. X., Zhow, T. S., Shen, J. Y., Chen, H. Z. |
| المصدر: |
European Heart Journal; 1991, Vol. 12 Issue suppl_D, p39-43, 5p |
| مستخلص: |
The effects of dexamethasone on cultured rat beating heart cells experimentally infected with coxsackievirus B2 were investigated at an early stage (1–3 days) post challenge. Changes in the release of the cardiac enzyme, aspartate amino-transferase (AST), beating %, cytopathic effect (CPE), virus titre, ultrastructure and alterations of the electrical activity were evaluated. The protective effects of dexamethasone on infected cells were abolished except the release of AST at 5 days post infection.These results suggest that steroids may benefit patients with severe myocarditis if conventional therapy for protection of the myocardium and modulation of immunologic function are concomitantly given. [ABSTRACT FROM PUBLISHER] |
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| قاعدة البيانات: |
Complementary Index |
