Fractional flow reserve versus angiography for guiding percutaneous coronary intervention
| العنوان: | Fractional flow reserve versus angiography for guiding percutaneous coronary intervention |
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| المؤلفون: | Tonino, Pim A L, De Bruyne, Bernard, Pijls, Nico H J, Siebert, Uwe, Ikeno, Fumiaki, van' t Veer, Marcel, Klauss, Volker, Manoharan, Ganesh, Engstrøm, Thomas, Oldroyd, Keith G, Ver Lee, Peter N, MacCarthy, Philip A, Fearon, William F, Rasmussen [FAME study investigators], Klaus, Frøbert [FAME study investigators], Ole |
| المساهمون: | Cardiovascular Biomechanics, Tonino, Pim A. L, De Bruyne, Bernard, Pijls, Nico H. J, Siebert, Uwe, Ikeno, Fumiaki, van' t. Veer, Marcel, Klauss, Volker, Manoharan, Ganesh, Engstrøm, Thoma, Oldroyd, Keith G, Ver Lee, Peter N, Barbato, Emanuele, Maccarthy, Philip A, Fearon, William F. |
| المصدر: | The New England Journal of Medicine, 360(3), 213-224. Massachussetts Medical Society Tonino, P A L, De Bruyne, B, Pijls, N H J, Siebert, U, Ikeno, F, van' t Veer, M, Klauss, V, Manoharan, G, Engstrøm, T, Oldroyd, K G, Ver Lee, P N, MacCarthy, P A, Fearon, W F, FAME Study Investigators, Rasmussen [FAME study investigators], K & Frøbert [FAME study investigators], O 2009, ' Fractional flow reserve versus angiography for guiding percutaneous coronary intervention ', The New England Journal of Medicine, vol. 360, no. 3, pp. 213-24 . https://doi.org/10.1056/NEJMoa0807611Test |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Male, medicine.medical_treatment, Aged, Angioplasty, Balloon, Coronary, Coronary Artery Disease, Coronary Restenosis, Female, Follow-Up Studies, Health Care Costs, Humans, Kaplan-Meier Estimate, Length of Stay, Middle Aged, Myocardial Infarction, Retreatment, Stents, Coronary Angiography, Drug-Eluting Stents, Fractional Flow Reserve, Myocardial, Fractional flow reserve, Coronary artery disease, Coronary Restenosi, Stent, Drug-Eluting Stent, Angioplasty, Transluminal, Percutaneous Coronary, Myocardial infarction, Angioplasty, Balloon, Coronary, medicine.diagnostic_test, General Medicine, Fractional Flow Reserve, Myocardial, surgical procedures, operative, Cardiology, Radiology, Human, medicine.medical_specialty, Follow-Up Studie, Internal medicine, medicine, cardiovascular diseases, Kaplan-Meiers Estimate, business.industry, Percutaneous coronary intervention, medicine.disease, Health Care Cost, Angiography, Conventional PCI, business |
| الوصف: | Udgivelsesdato: 2009-Jan-15 BACKGROUND: In patients with multivessel coronary artery disease who are undergoing percutaneous coronary intervention (PCI), coronary angiography is the standard method for guiding the placement of the stent. It is unclear whether routine measurement of fractional flow reserve (FFR; the ratio of maximal blood flow in a stenotic artery to normal maximal flow), in addition to angiography, improves outcomes. METHODS: In 20 medical centers in the United States and Europe, we randomly assigned 1005 patients with multivessel coronary artery disease to undergo PCI with implantation of drug-eluting stents guided by angiography alone or guided by FFR measurements in addition to angiography. Before randomization, lesions requiring PCI were identified on the basis of their angiographic appearance. Patients assigned to angiography-guided PCI underwent stenting of all indicated lesions, whereas those assigned to FFR-guided PCI underwent stenting of indicated lesions only if the FFR was 0.80 or less. The primary end point was the rate of death, nonfatal myocardial infarction, and repeat revascularization at 1 year. RESULTS: The mean (+/-SD) number of indicated lesions per patient was 2.7+/-0.9 in the angiography group and 2.8+/-1.0 in the FFR group (P=0.34). The number of stents used per patient was 2.7+/-1.2 and 1.9+/-1.3, respectively (P |
| اللغة: | English |
| تدمد: | 0028-4793 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba00edb01f3f8f5d0004c9a8bfe3b6d0Test https://hdl.handle.net/11573/1660393Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ba00edb01f3f8f5d0004c9a8bfe3b6d0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00284793 |
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