دورية أكاديمية
Helminths, polyparasitism, and the gut microbiome in the Philippines
| العنوان: | Helminths, polyparasitism, and the gut microbiome in the Philippines |
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| المؤلفون: | Gordon, CA, Krause, L, McManus, DP, Morrison, M, Weerakoon, KG, Connor, MC, Olveda, RM, Ross, AG, Gobert, GN |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2020 |
| المجموعة: | Griffith University: Griffith Research Online |
| مصطلحات موضوعية: | Microbiology, Zoology, Veterinary sciences, Ancylostoma, Ascaris, Gut microbiome, Hookworm, Schistosoma |
| الوصف: | Polyparasitism, involving soil-transmitted helminths. and Schistosoma blood flukes, is common in low to middle income countries. These helminths impact on the gut environment and can cause changes to the gut microbiome composition. Here we examined the gut microbiome in individuals with polyparasitism from two human cohorts in the Philippines utilising DNA sequencing-based profiling. Multiple helminth species infections were high with 70.3% of study participants harbouring at least two parasite species, and 16% harbouring at least five species. Increased numbers of helminth co-infections, in particular with the gut-resident soil-transmitted helminths, were significantly associated with increased bacterial diversity; however no significant parasite-gut microbiome associations were evident for individuals infected only with Schistosoma japonicum. In general, a healthy gut is associated with high bacterial diversity, which in these human cohorts may be the result of helminth-mediated immune modulation, or due to changes in the gut environment caused by these parasitic helminths. ; No Full Text |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0020-7519 |
| العلاقة: | International Journal for Parasitology; Gordon, CA; Krause, L; McManus, DP; Morrison, M; Weerakoon, KG; Connor, MC; Olveda, RM; Ross, AG; Gobert, GN, Helminths, polyparasitism, and the gut microbiome in the Philippines, International Journal for Parasitology, 2020, 50 (3), pp. 217-225; http://hdl.handle.net/10072/395823Test |
| DOI: | 10.1016/j.ijpara.2019.12.008 |
| الإتاحة: | https://doi.org/10.1016/j.ijpara.2019.12.008Test http://hdl.handle.net/10072/395823Test |
| حقوق: | open access |
| رقم الانضمام: | edsbas.6D506941 |
| قاعدة البيانات: | BASE |
| تدمد: | 00207519 |
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| DOI: | 10.1016/j.ijpara.2019.12.008 |