دورية أكاديمية
In vitro toxicity of carbon nanotubes, nano-graphite and carbon black, similar impacts of acid functionalization
| العنوان: | In vitro toxicity of carbon nanotubes, nano-graphite and carbon black, similar impacts of acid functionalization |
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| المؤلفون: | Figarol, Agathe, Pourchez, Jérémie, Boudard, Delphine, Forest, Valérie, Akono, Céline, Tulliani, Jean-Marc, Lecompte, Jean-Pierre, Cottier, Michèle, Bernache-Assolant, Didier, Grosseau, Philippe |
| المساهمون: | Centre Sciences des Processus Industriels et Naturels (SPIN-ENSMSE), École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom Paris (IMT)-Institut Mines-Télécom Paris (IMT), Département PROcédés Poudres, Interfaces, Cristallisation et Ecoulements (PROPICE-ENSMSE), Institut Mines-Télécom Paris (IMT)-Institut Mines-Télécom Paris (IMT)-SPIN, Laboratoire Georges Friedel (LGF-ENSMSE), Institut Mines-Télécom Paris (IMT)-Institut Mines-Télécom Paris (IMT)-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Laboratoire Interdisciplinaire d'Etude des Nanoparticules Aérosolisées (LINA-ENSMSE), Institut Mines-Télécom Paris (IMT)-Institut Mines-Télécom Paris (IMT)-CIS, Ingénierie des Biomatériaux et des Particules Inhalées (BIOPI-ENSMSE), Institut Fédératif de Recherche en Sciences et Ingénierie de la Santé (IFRESIS), Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Ecole Nationale Supérieure des Mines de St Etienne (ENSM ST-ETIENNE)-Centre National de la Recherche Scientifique (CNRS), Centre Ingénierie et Santé (CIS-ENSMSE), Centre Hospitalier Universitaire de Saint-Etienne CHU Saint-Etienne (CHU ST-E), Department of Applied Science and Technology Politecnico di Torino (DISAT), Politecnico di Torino = Polytechnic of Turin (Polito), Science des Procédés Céramiques et de Traitements de Surface (SPCTS), Université de Limoges (UNILIM)-Ecole Nationale Supérieure de Céramique Industrielle (ENSCI)-Institut des Procédés Appliqués aux Matériaux (IPAM), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Mines Paris - Centre des Matériaux, Politechnico di Torino - DISAT, Université de Limoges - SPCTS |
| المصدر: | ISSN: 0887-2333. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2015 |
| المجموعة: | Université Jean Monnet – Saint-Etienne: HAL |
| مصطلحات موضوعية: | Acid functionalization, Biological toxicity, Carbon black, Carbon nanotubes, Graphene, Nano-graphite, [SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering, [SDV.TOX]Life Sciences [q-bio]/Toxicology, [SPI]Engineering Sciences [physics], [SPI.MAT]Engineering Sciences [physics]/Materials |
| الوصف: | International audience ; Carbon nanotubes (CNT) and nano-graphite (NG) are graphene-based nanomaterials which share exceptional physicochemical properties, but whose health impacts are unfortunately still not well understood. On the other hand, carbon black (CB) is a conventional and widely studied material. The comparison of these three carbon-based nanomaterials is thus of great interest to improve our understanding of their toxicity. An acid functionalization was carried out on CNT, NG and CB so that, after a thorough characterization, their impacts on RAW 264.7 macrophages could be compared for a similar surface chemistry (15 to 120 μg·mL − 1 nanomaterials, 90-min to 24-h contact). Functionalized nanomaterials triggered a weak cytotoxicity similar to the pristine nanomaterials. Acid functionalization increased the pro-inflammatory response except for CB which did not trigger any TNF-α production before or after functionalization, and seemed to strongly decrease the oxidative stress. The toxicological impact of acid functionalization appeared thus to follow a similar trend whatever the carbon-based nanomaterial. At equivalent dose expressed in surface and equivalent surface chemistry, the toxicological responses from murine macrophages to NG were higher than for CNT and CB. It seemed to correspond to the hypothesis of a platelet and fiber paradigm. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | emse-01212432; https://hal-emse.ccsd.cnrs.fr/emse-01212432Test; https://hal-emse.ccsd.cnrs.fr/emse-01212432/documentTest; https://hal-emse.ccsd.cnrs.fr/emse-01212432/file/Figarol_Pourchez%20Toxicology%20in%20Vitro.pdfTest |
| DOI: | 10.1016/j.tiv.2015.09.014 |
| الإتاحة: | https://doi.org/10.1016/j.tiv.2015.09.014Test https://hal-emse.ccsd.cnrs.fr/emse-01212432Test https://hal-emse.ccsd.cnrs.fr/emse-01212432/documentTest https://hal-emse.ccsd.cnrs.fr/emse-01212432/file/Figarol_Pourchez%20Toxicology%20in%20Vitro.pdfTest |
| حقوق: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.C3CD5A8A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.tiv.2015.09.014 |
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