التفاصيل البيبلوغرافية
| العنوان: |
Atypical astroglial pTDP‐43 pathology in astroglial predominant tauopathy. |
| المؤلفون: |
Gelpi, Ellen, Aldecoa, Iban, Lopez‐Villegas, Dolores, Abellan‐Vidal, Maria Teresa, Mercadel‐Fañanas, Pilar, Fortea, Juan, Ribosa, Roser, Morenas, Estrella, Gomez‐Anson, Beatriz, Molina‐Porcel, Laura, Ximelis, Teresa, Borrego, Sergi, Antonell, Anna, Rovelet‐Lecrux, Anne, Klotz, Sigrid, Andres‐Benito, Pol, Sanchez‐Valle, Raquel, Ferrer, Isidre |
| المصدر: |
Neuropathology & Applied Neurobiology; Dec2021, Vol. 47 Issue 7, p1109-1113, 5p |
| مصطلحات موضوعية: |
PATHOLOGY, TAU proteins, GRANULE cells, AMYOTROPHIC lateral sclerosis, FRONTAL lobe, MOTOR neuron diseases, MONOCLONAL antibodies, NEUROFIBRILLARY tangles, TAUOPATHIES |
| مستخلص: |
Josephs et al. reported that preinclusions might be better identified with antibodies against full-length TDP-43.3 This astrocytic pTDP-43 pathology clearly followed the pathology pattern observed with the AT8 antibody at the cellular and anatomical level. Keywords: astroglial tauopathy; FTLD-Tau; glia limitans/perivascular glia; pTDP-43; TDP-43 EN astroglial tauopathy FTLD-Tau glia limitans/perivascular glia pTDP-43 TDP-43 1109 1113 5 11/24/21 20211201 NES 211201 We observed atypical astrocytic pTDP-43 pathology in astroglial predominant tauopathy. Glial and neuronal tau pathology in tauopathies: characterization of disease-specific phenotypes and tau pathology progression. Whether the dual pTDP-43 and pTau pathology represents a specific disease signature and whether potential protein-interactions lead to this complex pathology deserves further studies. [Extracted from the article] |
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| قاعدة البيانات: |
Complementary Index |
