المؤلفون: Kumar, Avi, Cordes, Thekla, Thalacker-Mercer, Anna E, Pajor, Ana M, Murphy, Anne N, Metallo, Christian M

المصدر: Cell Reports. 36(11)

مصطلحات موضوعية: Nutrition, Liver Disease, Digestive Diseases, Aetiology, 2.1 Biological and endogenous factors, Acetyl Coenzyme A, Adult, Animals, Carcinoma, Hepatocellular, Cell Hypoxia, Cell Line, Tumor, Cell Survival, Citrates, Female, Gene Editing, Glutamine, Humans, Lipogenesis, Liver Neoplasms, Male, Neurons, Nutrients, Rats, Symporters, Zinc, NaCT, SLC13A5, citrate, hepatocellular carcinoma, lipogenesis, neurons, zinc, Biochemistry and Cell Biology, Medical Physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1c86r4x2Test

المؤلفون: Jiang, Lei, Shestov, Alexander A, Swain, Pamela, Yang, Chendong, Parker, Seth J, Wang, Qiong A, Terada, Lance S, Adams, Nicholas D, McCabe, Michael T, Pietrak, Beth, Schmidt, Stan, Metallo, Christian M, Dranka, Brian P, Schwartz, Benjamin, DeBerardinis, Ralph J

المصدر: Nature. 532(7598)

مصطلحات موضوعية: Cell Line, Tumor, Spheroids, Cellular, Extracellular Matrix, Mitochondria, Cytosol, Humans, Neoplasms, Reactive Oxygen Species, Citric Acid, Isocitrates, NADP, Isocitrate Dehydrogenase, Glucose, Glutamic Acid, Glutamine, Cell Adhesion, Cell Proliferation, Cell Hypoxia, Contact Inhibition, Oxidation-Reduction, Oxidative Stress, Homeostasis, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9tn6w9h6Test

المؤلفون: Vacanti, Nathaniel M, Divakaruni, Ajit S, Green, Courtney R, Parker, Seth J, Henry, Robert R, Ciaraldi, Theodore P, Murphy, Anne N, Metallo, Christian M

المصدر: Molecular Cell. 56(3)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Industrial Biotechnology, Nutrition, Animals, Cell Line, Tumor, Cell Proliferation, Citric Acid Cycle, Fatty Acids, Glutamine, Humans, Lipogenesis, Metabolic Flux Analysis, Mice, Muscle Fibers, Skeletal, Oxidation-Reduction, Proprotein Convertase 1, Proprotein Convertase 2, Pyruvic Acid, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1cp6n62cTest

المؤلفون: Grassian, Alexandra R, Parker, Seth J, Davidson, Shawn M, Divakaruni, Ajit S, Green, Courtney R, Zhang, Xiamei, Slocum, Kelly L, Pu, Minying, Lin, Fallon, Vickers, Chad, Joud-Caldwell, Carol, Chung, Franklin, Yin, Hong, Handly, Erika D, Straub, Christopher, Growney, Joseph D, Heiden, Matthew G Vander, Murphy, Anne N, Pagliarini, Raymond, Metallo, Christian M

المصدر: Cancer Research. 74(12)

مصطلحات موضوعية: Cancer, Genetics, 2.1 Biological and endogenous factors, Aetiology, Animals, Antineoplastic Agents, Cell Hypoxia, Citric Acid Cycle, Enzyme Inhibitors, Glutamine, HCT116 Cells, Humans, Isocitrate Dehydrogenase, Mice, Mitochondria, Mutation, Missense, Oxidation-Reduction, Stress, Physiological, Xenograft Model Antitumor Assays, Oncology and Carcinogenesis, Oncology & Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/69g6m263Test

المؤلفون: Walther, Jason L., Metallo, Christian M., Zhang, Jie¹, Stephanopoulos, Gregory gregstep@mit.edu

المصدر: Metabolic Engineering. Mar2012, Vol. 14 Issue 2, p162-171. 10p.

مصطلحات موضوعية: *TRACERS (Biology), *METABOLIC flux analysis, *BIOMASS energy, *GLUTAMINE, *CANCER cell proliferation, *CELL metabolism, *BIOSYNTHESIS

المؤلفون: Metallo, Christian M.¹, Gameiro, Paulo A.², Bell, Eric L.³, Mattaini, Katherine R.⁴, Yang, Juanjuan⁵, Hiller, Karsten¹, Jewell, Christopher M.⁶, Johnson, Zachary R.⁶, Irvine, Darrell J.⁷, Guarente, Leonard³, Kelleher, Joanne K.⁸, Vander Heiden, Matthew G.⁹, Iliopoulos, Othon⁵, Stephanopoulos, Gregory⁸

المصدر: Nature. 1/19/2012, Vol. 481 Issue 7381, p380-384. 5p. 4 Graphs.

مصطلحات موضوعية: *GLUTAMINE, *FATTY acid synthesis, *HYPOXEMIA, *TRICARBOXYLIC acids, *LIPID synthesis, *CARBOXYLATION, *CELL proliferation

المؤلفون: Metallo, Christian M.¹, Vander Heiden, Matthew G.^2,3 mvh@mit.edu

المصدر: Genes & Development. 12/15/2010, Vol. 24 Issue 24, p2717-2722. 7p.

مصطلحات موضوعية: *GLUCOSE, *METABOLISM, *GROWTH factors, *GLYCOSYLATION, *GLUTAMINE, *PROTEINS

المؤلفون: Daniela Gaglio, Marcella Bonanomi, Silvia Valtorta, Rohit Bharat, Marilena Ripamonti, Federica Conte, Giulia Fiscon, Nicole Righi, Elisabetta Napodano, Federico Papa, Isabella Raccagni, Seth J. Parker, Ingrid Cifola, Tania Camboni, Paola Paci, Anna Maria Colangelo, Marco Vanoni, Christian M. Metallo, Rosa Maria Moresco, Lilia Alberghina

المساهمون: Gaglio, Daniela, Bonanomi, Marcella, Valtorta, Silvia, Bharat, Rohit, Ripamonti, Marilena, Conte, Federica, Fiscon, Giulia, Righi, Nicole, Napodano, Elisabetta, Papa, Federico, Raccagni, Isabella, Parker, Seth J., Cifola, Ingrid, Camboni, Tania, Paci, Paola, Maria Colangelo, Anna, Vanoni, Marco, Metallo, Christian M., Maria Moresco, Rosa, Alberghina, Lilia

مصطلحات موضوعية: Cancer Metabolism, Metabolic rewiring, Metabolic cancer therapy, Metabolic signature, Glycolysi, Glutamine, Combinatorial drug treatment, Precision oncology, Metabolic connectivity

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000576836900001; volume:8; firstpage:1; lastpage:15; numberofpages:15; journal:CANCER & METABOLISM; http://hdl.handle.net/11573/1570717Test

الإتاحة: https://doi.org/10.1186/s40170-020-00227-4Test
http://hdl.handle.net/11573/1570717Test

المؤلفون: Natalie I. Vokes, Katherine R. Mattaini, Christian M. Metallo, William J. Israelsen, M. G. Vander Heiden, Jason W. Locasale, Brian P. Fiske, Gregory Stephanopoulos, Lewis C. Cantley, Sophia Y. Lunt, Talya L. Dayton

المساهمون: Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Vander Heiden, Matthew G., Lunt, Sophia Yunkyungkwon, Dayton, Talya Lucia, Fiske, Brian Prescott, Israelsen, William James, Mattaini, Katherine Ruth, Vokes, N. I., Stephanopoulos, G., Metallo, Christian M.

المصدر: Vander Heiden via Courtney Crummett

مصطلحات موضوعية: Cell growth, Glutamine, Pyruvate Kinase, Lipid metabolism, Metabolism, Biology, PKM2, Biochemistry, Cell biology, Metabolic pathway, Glucose, Serine, Genetics, Animals, Humans, Glycolysis, Molecular Biology, Flux (metabolism), Metabolic Networks and Pathways, Pyruvate kinase, Cell Proliferation

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c3d82c59f4b630fefae1e3cbf2ca24Test
https://doi.org/10.1101/sqb.2012.76.010900Test

المؤلفون: Zachary R. Johnson, Gregory Stephanopoulos, Darrell J. Irvine, Christopher M. Jewell, Leonard Guarente, Othon Iliopoulos, Juanjuan Yang, Matthew G. Vander Heiden, Joanne K. Kelleher, Katherine R. Mattaini, Christian M. Metallo, Karsten Hiller, Eric L. Bell, Paulo A. Gameiro

المساهمون: Massachusetts Institute of Technology. Department of Biology, Massachusetts Institute of Technology. Department of Chemical Engineering, Massachusetts Institute of Technology. Department of Materials Science and Engineering, Koch Institute for Integrative Cancer Research at MIT, Metallo, Christian M., Gameiro, Paulo A., Hiller, Karsten, Kelleher, Joanne Keene, Stephanopoulos, Gregory, Bell, Eric L., Mattaini, Katherine Ruth, Guarente, Leonard Pershing, Vander Heiden, Matthew G., Jewell, Christopher M., Johnson, Zachary, Irvine, Darrell J.

المصدر: PMC

مصطلحات موضوعية: ATP citrate lyase, Glutamine, Citric Acid Cycle, Palmitic Acid, Biology, CD8-Positive T-Lymphocytes, Article, Acetyl Coenzyme A, Lipid biosynthesis, Cell Line, Tumor, Basic Helix-Loop-Helix Transcription Factors, Humans, Carcinoma, Renal Cell, Cells, Cultured, Multidisciplinary, Lipogenesis, Aryl Hydrocarbon Receptor Nuclear Translocator, Lipid metabolism, Metabolism, Hypoxia-Inducible Factor 1, alpha Subunit, Carbon, Cell Hypoxia, Isocitrate Dehydrogenase, Kidney Neoplasms, Citric acid cycle, Oxygen, Biochemistry, Anaerobic glycolysis, Von Hippel-Lindau Tumor Suppressor Protein, Ketoglutaric Acids, Oxidation-Reduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8054de36a9335596ec49fe123185784Test
https://orcid.org/0000-0003-0046-1360Test