دورية أكاديمية
The gut microbiota in retinal diseases
| العنوان: | The gut microbiota in retinal diseases |
|---|---|
| المؤلفون: | Bringer, Marie-Agnès, Gabrielle, Pierre-Henry, Bron, Alain, M, Creuzot-Garcher, Catherine, Acar, Niyazi |
| المساهمون: | Centre des Sciences du Goût et de l'Alimentation Dijon (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté COMUE (UBFC), Service d'Ophtalmologie (CHU de Dijon), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), ANR-11-LABX-0021,Lipstic,Lipoprotéines et santé : prévention et traitement des maladies inflammatoires non vasculaires et du cancer(2011), ANR-15-IDEX-0003,BFC,ISITE " BFC(2015) |
| المصدر: | ISSN: 0014-4835. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2022 |
| المجموعة: | Université de Bourgogne (UB): HAL |
| مصطلحات موضوعية: | glaucoma, gut microbiota, probiotics, retina, age-related macular degeneration, diabetic retinopathy, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, [SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs |
| الوصف: | International audience ; The gut microbiota is a complex ecosystem that inhabits the gastrointestinal tract and consists of archaea, fungi, viruses, and bacteria, with bacteria being dominant. From birth onwards, it coevolves dynamically together with the host. The composition of the gut microbiota is under the influence of a complex interplay between both host and environmental factors. Scientific advances in the past few decades have shown that it is essential in maintaining homeostasis and tipping the balance between health and disease. In addition to its role in food digestion, the gut microbiota is implicated in regulating multiple physiological processes in the host gut mucosa and in distant organs such as the brain. Persistent imbalance between gut microbial communities, termed "dysbiosis," has been associated with several inflammatory and metabolic diseases as well as with central nervous system disorders. In this review, we present the state of the art of current knowledge on an emerging concept, the microbiota-retina axis, and the potential role of its disturbance in the development of retinopathies. We also describe several microbiota-targeting strategies that could constitute preventive and therapeutic tools for retinopathies. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| ردمك: | 978-0-01-448352-5 0-01-448352-1 |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/34856206; hal-03471216; https://hal.inrae.fr/hal-03471216Test; https://hal.inrae.fr/hal-03471216/documentTest; https://hal.inrae.fr/hal-03471216/file/S0014483521004334.pdfTest; PII: S0014-4835(21)00433-4; PUBMED: 34856206; WOS: 000735436100004 |
| DOI: | 10.1016/j.exer.2021.108867 |
| الإتاحة: | https://doi.org/10.1016/j.exer.2021.108867Test https://hal.inrae.fr/hal-03471216Test https://hal.inrae.fr/hal-03471216/documentTest https://hal.inrae.fr/hal-03471216/file/S0014483521004334.pdfTest |
| حقوق: | http://creativecommons.org/licenses/by-ncTest/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.6F9E9B6E |
| قاعدة البيانات: | BASE |
| ردمك: | 9780014483525 0014483521 |
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| DOI: | 10.1016/j.exer.2021.108867 |