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1دورية أكاديميةA cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation.
المؤلفون: Artem Blagodatski, Vera Batrak, Sabine Schmidl, Ulrike Schoetz, Randolph B Caldwell, Hiroshi Arakawa, Jean-Marie Buerstedde
المصدر: PLoS Genetics, Vol 5, Iss 1, p e1000332 (2009)
وصف الملف: electronic resource
العلاقة: http://europepmc.org/articles/PMC2607555?pdf=renderTest; https://doaj.org/toc/1553-7390Test; https://doaj.org/toc/1553-7404Test
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المصدر: The Journal of Immunology. 191:1556-1566
مصطلحات موضوعية: Genetics, Reporter gene, Immunology, Immunology and Allergy, Somatic hypermutation, Locus (genetics), E-box, Cytidine deaminase, Biology, Sequence motif, Genome, Gene
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::59827adac5b35501fc0896414094d2a3Test
https://doi.org/10.4049/jimmunol.1300969Test -
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المؤلفون: Jean-Marie Buerstedde, Hiroshi Arakawa
المصدر: Philosophical Transactions of the Royal Society B: Biological Sciences. 364:639-644
مصطلحات موضوعية: Genetics, biology, Genetic Variation, Somatic hypermutation, Locus (genetics), Review, Cytidine deaminase, General Biochemistry, Genetics and Molecular Biology, Cell Line, Regulatory sequence, Cytidine Deaminase, Proliferating Cell Nuclear Antigen, Uracil-DNA glycosylase, Activation-induced (cytidine) deaminase, biology.protein, Animals, Immunoglobulin Light Chains, Somatic Hypermutation, Immunoglobulin, Gene conversion, Uracil-DNA Glycosidase, General Agricultural and Biological Sciences, Chickens, Gene
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9839fedd2b59c343625d816164555fTest
https://doi.org/10.1098/rstb.2008.0202Test -
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المؤلفون: J. Bachl, Jean-Marie Buerstedde, Randolph B. Caldwell
المصدر: Cytogenet. Genome Res. 117, 189-194 (2007)
مصطلحات موضوعية: B-Lymphocytes, Focus (computing), business.industry, Gene Expression, Biology, Cell Line, Protein evolution, Biotechnology, Green fluorescent protein, Directed enzyme evolution, In-vitro recombination, Somatic hypermutation, Gene conversion, Phage display, Region hypermutation, Antibody diversity, Escherichia-coli, Lympocyte line, B cell line, Genes, Reporter, Mutation, Genetics, Animals, Humans, business, Chickens, Molecular Biology, Genetics (clinical), Pharmaceutical industry
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8c0db9cc2e133ab83b2b3ef573c606Test
https://doi.org/10.1159/000103179Test -
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المؤلفون: K. Koskela, Pekka Kohonen, Olli Lassila, Pia Nieminen, Jean-Marie Buerstedde
المصدر: Immunogenetics. 55:412-422
مصطلحات موضوعية: B-Lymphocytes, animal structures, Avian immune system, Reverse Transcriptase Polymerase Chain Reaction, Gene Expression Profiling, T-Lymphocytes, Immunology, Cell, Germinal center, Cell Differentiation, Biology, Molecular biology, Gene expression profiling, medicine.anatomical_structure, Gene expression, Genetics, medicine, Animals, Compartment (development), Stem cell, Chickens, Gene
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6a08436146037191391c21db33de5cTest
https://doi.org/10.1007/s00251-003-0592-7Test -
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المؤلفون: Noel F. Lowndes, David G. Schatz, Jean-Marie Buerstedde
المصدر: eLife
eLife, Vol 3 (2014)مصطلحات موضوعية: homologous recombination, Mice, Cytidine deamination, Genes, Reporter, Holliday junction, Activation-induced (cytidine) deaminase, AID, Crossing Over, Genetic, Biology (General), Heteroduplex formation, Sequence Deletion, Genetics, B-Lymphocytes, biology, General Neuroscience, Nucleic Acid Heteroduplexes, General Medicine, Non-homologous end joining, Medicine, Research Article, QH301-705.5, Science, chicken, Immunology, Green Fluorescent Proteins, Molecular Sequence Data, Non-allelic homologous recombination, Gene Conversion, DNA repair, General Biochemistry, Genetics and Molecular Biology, Cell Line, Cytidine Deaminase, Sequence Homology, Nucleic Acid, Animals, Humans, Gene conversion, mouse, Repetitive Sequences, Nucleic Acid, General Immunology and Microbiology, Base Sequence, Models, Genetic, Recombinational DNA Repair, Cell Biology, Molecular biology, Immunoglobulin Switch Region, Luminescent Proteins, biology.protein, Somatic Hypermutation, Immunoglobulin, Homologous recombination, Chickens
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11603bff400fd5664c2ec1f6a02dad2Test
http://europepmc.org/articles/PMC4080448Test -
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المؤلفون: David G. Schatz, Jessica J. McDonald, Jean-Marie Buerstedde, Jukka Alinikula, Hiroshi Arakawa
المصدر: PLoS Biology
PLoS Biology, Vol 12, Iss 4, p e1001831 (2014)مصطلحات موضوعية: B Cells, Transcription, Genetic, Lymphocyte Activation, Biochemistry, E-Box Elements, White Blood Cells, Gene Knockout Techniques, Mice, 0302 clinical medicine, Animal Cells, Nucleic Acids, Molecular Cell Biology, Biology (General), Immune Response, 0303 health sciences, B-Lymphocytes, Immune System Proteins, MEF2 Transcription Factors, General Neuroscience, NF-kappa B, Cytidine deaminase, 3. Good health, Enhancer Elements, Genetic, Cellular Types, General Agricultural and Biological Sciences, DNA modification, Research Article, QH301-705.5, Immune Cells, DNA transcription, Immunology, Green Fluorescent Proteins, Somatic hypermutation, Biology, General Biochemistry, Genetics and Molecular Biology, Antibodies, Cell Line, Affinity maturation, 03 medical and health sciences, Immunoglobulin kappa-Chains, Immunoglobulin lambda-Chains, Cytidine Deaminase, Genetics, Animals, Humans, Enhancer, Uracil-DNA Glycosidase, Gene, Transcription factor, 030304 developmental biology, Blood Cells, Binding Sites, General Immunology and Microbiology, Biology and life sciences, Point mutation, Proteins, DNA, Cell Biology, Molecular biology, Mutation, Gene expression, Somatic Hypermutation, Immunoglobulin, Chickens, Sequence Alignment, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a2c7f03381e457777efb988037e9aaTest
http://europepmc.org/articles/PMC3972084Test -
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المؤلفون: Jean-Marie Buerstedde, Andy Law, Paul Geroth, Dmitry Lodygin, Igor Abdrakhmanov, Hiroshi Arakawa, Jiri Plachy, Berndt Korn
المصدر: Genome Research. 10:2062-2069
مصطلحات موضوعية: animal structures, Databases, Factual, Molecular Sequence Data, Biology, computer.software_genre, Bursa of Fabricius, Gene mapping, Sequence Homology, Nucleic Acid, Gene expression, Genetics, Animals, Humans, Database search engine, Lymphocytes, Gene conversion, Gene, Genetics (clinical), Expressed Sequence Tags, Internet, Expressed sequence tag, Genes, Immunoglobulin, Database, Gene Expression Profiling, Computational Biology, Genome project, Resources, Gene expression profiling, Genes, Multigene Family, embryonic structures, Chickens, Sequence Alignment, human activities, computer, Software
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139c52c042b36e2ffb5771be1a79e419Test
https://doi.org/10.1101/gr.10.12.2062Test -
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المؤلفون: Jean-Marie Buerstedde, Karl Heinimann, Hansjakob Müller, Karl Siebold, Rodney J. Scott, Walter Weber, Zuzana Dobbie, Michèle Attenhofer
المصدر: Cancer. 85:2512-2518
مصطلحات موضوعية: Genetics, congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Amsterdam criteria, Mutation, business.industry, Colorectal cancer, nutritional and metabolic diseases, Cancer, Microsatellite instability, Gene mutation, medicine.disease, medicine.disease_cause, digestive system diseases, Germline mutation, Oncology, Medicine, DNA mismatch repair, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7000aa89726d22f353b59788b793bb52Test
https://doi.org/10.1002Test/(sici)1097-0142(19990615)85:12<2512::aid-cncr4>3.0.co;2-g -
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المؤلفون: Yuko Yamaguchi-Iwai, Akira Shinohara, Eiichiro Sonoda, Olga Bezzubova, Ciaran G. Morrison, Minoru Takata, Jean-Marie Buerstedde, Shunichi Takeda
المصدر: Molecular and Cellular Biology. 18:6430-6435
مصطلحات موضوعية: Immunoglobulin gene, DNA Repair, Cell Survival, DNA repair, FLP-FRT recombination, genetic processes, Saccharomyces cerevisiae, RAD52, RAD51, Fluorescent Antibody Technique, Biology, Transfection, Genetic recombination, Cell Line, Animals, Cell Growth and Development, Molecular Biology, Recombination, Genetic, Genetics, B-Lymphocytes, X-Rays, fungi, Cell Biology, Methyl Methanesulfonate, biology.organism_classification, Cell biology, DNA-Binding Proteins, enzymes and coenzymes (carbohydrates), Immunoglobulin M, Gene Targeting, Cisplatin, Homologous recombination, Chickens, Mutagens
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6027f36bac722721b6d45ff49005ab2aTest
https://doi.org/10.1128/mcb.18.11.6430Test