المؤلفون: Mazahir T. Hasan, Elena Y. Bryleva, Stephanie R. Murphy, Zachary D. Bowen, Catherine C.Y. Chang, Ta-Yuan Chang, Godwin Dogbevia

المصدر: Molecular Therapy. 21:1497-1506

مصطلحات موضوعية: Male, viruses, Genetic enhancement, Genetic Vectors, Gene Expression, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Alzheimer Disease, Transduction, Genetic, Gene Order, Drug Discovery, Gene expression, Genetics, medicine, Amyloid precursor protein, Gene Knockdown Techniques, Animals, Humans, Acetyl-CoA C-Acetyltransferase, Molecular Biology, 030304 developmental biology, Mice, Knockout, Neurons, Pharmacology, 0303 health sciences, Gene knockdown, Amyloid beta-Peptides, ACAT1, biology, Brain, Genetic Therapy, Dependovirus, medicine.disease, Molecular biology, 3. Good health, Disease Models, Animal, MicroRNAs, chemistry, Cholesteryl ester, biology.protein, Cancer research, Molecular Medicine, Original Article, Female, Alzheimer's disease, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82249744dd0e32e7d7d405c890b4211aTest
https://doi.org/10.1038/mt.2013.118Test

المؤلفون: Robert A. Maue, Brent T. Harris, Ivan A. Borbon, Christine M. Wooley, Maximillian A. Rogers, David J. Graber, Catherine C.Y. Chang, Robert W. Burgess, Leslie P. Henderson, Robert P. Erickson, Theodore P. Trouard, Marie T. Vanier, Carlos A. A. Penatti, Kevin L. Seburn, Bing Wang, John Totenhagen, Benjamin S. Szwergold, Ta-Yuan Chang, Donna M. Porter

المصدر: Human Molecular Genetics. 21:730-750

مصطلحات موضوعية: Reflex, Startle, DNA Mutational Analysis, Purkinje cell, Mutant, medicine.disease_cause, Mice, Purkinje Cells, Gangliosides, hemic and lymphatic diseases, Age of Onset, Lung, Myelin Sheath, Genetics (clinical), Mutation, Membrane Glycoproteins, Homozygote, Intracellular Signaling Peptides and Proteins, Brain, Niemann-Pick Disease, Type C, Articles, General Medicine, Endoplasmic Reticulum Stress, Null allele, Survival Rate, Cholesterol, Phenotype, medicine.anatomical_structure, Disease Progression, lipids (amino acids, peptides, and proteins), Microglia, Niemann–Pick disease, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Biology, Niemann-Pick C1 Protein, Internal medicine, Genetics, medicine, Animals, Humans, Point Mutation, RNA, Messenger, Proteostasis Deficiencies, Molecular Biology, Alleles, Macrophages, Point mutation, nutritional and metabolic diseases, Lipid Metabolism, medicine.disease, Startle reaction, nervous system diseases, Disease Models, Animal, Endocrinology, Astrocytes, NPC1, Carrier Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3183f2b0e75b63b8fff7fd0c1c1717d6Test
https://doi.org/10.1093/hmg/ddr505Test

المؤلفون: Song Li, Li-Hao Huang, Thomas Ho, Catherine C.Y. Chang, Ta-Yuan Chang, Koji Nishi, Ruhong Dong

المصدر: The FEBS journal. 281(7)

مصطلحات موضوعية: Proline, Sterol O-acyltransferase, CHO Cells, Biochemistry, Isozyme, Polymorphism, Single Nucleotide, Article, Cricetulus, Cricetinae, Animals, Humans, Acetyl-CoA C-Acetyltransferase, Site-directed mutagenesis, Molecular Biology, Genetics, chemistry.chemical_classification, biology, Active site, Cell Biology, Protein Structure, Tertiary, Transmembrane domain, Enzyme, chemistry, Acyltransferases, Cytoplasm, Mutation, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0de84b246857f2b154e4675a2912a4Test
https://pubmed.ncbi.nlm.nih.gov/24517390Test

المؤلفون: Bo-Liang Li, Ming Lu, Guangjing Hu, Xi-Xiao Wei, Fajun Nan, Xihan Hu, Ying Xiong, Catherine C.Y. Chang, Bao-Liang Song, Xiao-Nan Zhao, Jiajia Xu, Jia Li, Ta-Yuan Chang, Yin-Kun Liu, Qin Li

المصدر: Journal of molecular cell biology. 5(6)

مصطلحات موضوعية: Male, Carcinoma, Hepatocellular, Mice, Nude, Biology, In Vitro Techniques, chemistry.chemical_compound, Cell Line, Tumor, Genetics, Animals, Humans, Secretion, Liver X receptor, Molecular Biology, neoplasms, Cholesterol, Liver Neoplasms, Cell Biology, General Medicine, Hep G2 Cells, Articles, HCCS, Xenograft Model Antitumor Assays, digestive system diseases, Metabolic pathway, chemistry, Cell culture, DNA methylation, Cancer research, lipids (amino acids, peptides, and proteins), Intracellular, Metabolic Networks and Pathways

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5af6222dec8c99cf6431c5e7fca7c39Test
https://pubmed.ncbi.nlm.nih.gov/24163426Test

المؤلفون: Ta-Yuan Chang, Xialu Li, Lawrence Chan, Jonathan P. Park, Zhang-Mei Ma, Xin-Ying Yang, Catherine C.Y. Chang, Bo-Liang Li, Song Lin, Zhijun Duan, Walter W. Noll, T.K. Mohandas, Oneil Lee

المصدر: Journal of Biological Chemistry. 274:11060-11071

مصطلحات موضوعية: Chromosome 7 (human), Genetics, Restriction Mapping, RNA, Promoter, DNA, Exons, Cell Biology, Biology, Biochemistry, Molecular biology, Introns, genomic DNA, Exon, Exon trapping, Chromosomes, Human, Pair 1, Humans, Coding region, RNA, Messenger, Tandem exon duplication, 5' Untranslated Regions, Promoter Regions, Genetic, Molecular Biology, Chromosomes, Human, Pair 7, Sterol O-Acyltransferase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1af3762d62a749e9df23ec8800f82dTest
https://doi.org/10.1074/jbc.274.16.11060Test

المؤلفون: Diane M. Spillane, Catherine C.Y. Chang, Mazahir T. Hasan, Jean Chin, Jun Chen, Ta-Yuan Chang

المصدر: Current Opinion in Lipidology

مصطلحات موضوعية: Somatic cell, Endocrinology, Diabetes and Metabolism, CHO Cells, Intracellular cholesterol transport, chemistry.chemical_compound, Cricetinae, Lysosome, Genetics, medicine, Animals, Molecular Biology, Nutrition and Dietetics, Chemistry, Cholesterol, Chinese hamster ovary cell, Nuclear Proteins, Biological Transport, Cell Biology, Sterol, DNA-Binding Proteins, medicine.anatomical_structure, Biochemistry, Mutation, CCAAT-Enhancer-Binding Proteins, Sterol Regulatory Element Binding Protein 1, lipids (amino acids, peptides, and proteins), Cholesterol Esters, Cardiology and Cardiovascular Medicine, Intracellular, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3a416196b8a03c9e203f7fc3ee5635Test
https://doi.org/10.1097/00041433-199704000-00003Test

المؤلفون: Zhiguang Su, Qian Wang, Zongji Lu, Catherine C.Y. Chang, Weibin Shi, Toru Miyoshi, Zuobiao Yuan

المصدر: PLoS ONE
PLoS ONE, Vol 6, Iss 10, p e25344 (2011)

مصطلحات موضوعية: Apolipoprotein E, Male, Candidate gene, Heredity, Apolipoprotein B, Mouse, lcsh:Medicine, 030204 cardiovascular system & hematology, Biochemistry, Mice, 0302 clinical medicine, lcsh:Science, 0303 health sciences, SOAT1, Mice, Inbred C3H, Multidisciplinary, Genome, biology, Linkage (Genetics), Animal Models, Lipids, Sterols, Cholesterol, Medicine, lipids (amino acids, peptides, and proteins), Female, Genetic Engineering, Research Article, Biotechnology, Lipoproteins, Sterol O-acyltransferase, Molecular Sequence Data, Quantitative Trait Loci, Single-nucleotide polymorphism, Hyperlipidemias, Mice, Transgenic, Quantitative trait locus, Apolipoprotein Genes, 03 medical and health sciences, Apolipoproteins E, Model Organisms, Species Specificity, Genetics, Animals, Genetic Predisposition to Disease, Amino Acid Sequence, Allele, Biology, Crosses, Genetic, 030304 developmental biology, Base Sequence, Quantitative Traits, lcsh:R, Proteins, Lipid Metabolism, Molecular biology, Chromosomes, Mammalian, Mice, Inbred C57BL, Metabolism, Apolipoproteins, Genetics of Disease, biology.protein, Macrophages, Peritoneal, lcsh:Q, Lod Score, Animal Genetics, Sterol O-Acyltransferase, Transgenics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5595b827620421c60361c9ff020c8250Test
https://pubmed.ncbi.nlm.nih.gov/22022387Test

المؤلفون: Catherine C.Y. Chang, Jie Sun, Ta-Yuan Chang

المصدر: Frontiers in Biology. 6

مصطلحات موضوعية: Ecology, MBOAT, Computational biology, Biology, Proteomics, Transmembrane domain, Protein acylation, Biochemistry, Acyltransferases, Genetics, Human genome, Asparagine, Gene, Ecology, Evolution, Behavior and Systematics, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::54dfe69b87e5c2d1328e9e70a99c5490Test
https://doi.org/10.1007/s11515-011-1149-zTest

المؤلفون: Oneil Nicohlas Gardner, Ta-Yuan Chang, Catherine C.Y Chang

المصدر: The FASEB Journal. 24

مصطلحات موضوعية: Biochemistry, Chemistry, Genetics, Molecular Biology, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ab76d694a3b3591d392ba89929f3b831Test
https://doi.org/10.1096/fasebj.24.1_supplement.lb108Test

المؤلفون: Maximillian A. Rogers, Stephanie R. Murphy, Ta-Yuan Chang, Catherine C.Y. Chang, Elena Y. Bryleva

المصدر: IUBMB Life.

مصطلحات موضوعية: Risk, medicine.medical_specialty, Clinical Biochemistry, Drug target, Disease, Biochemistry, Amyloid beta-Protein Precursor, Mice, chemistry.chemical_compound, Alzheimer Disease, Internal medicine, Genetics, medicine, Amyloid precursor protein, Animals, Humans, Cholesterol metabolism, Molecular Biology, Neurons, ACAT1, Esterification, biology, Cholesterol, business.industry, Neurodegenerative Diseases, Lipid metabolism, Cell Biology, Lipid Metabolism, medicine.disease, Hydroxycholesterols, Endocrinology, chemistry, biology.protein, lipids (amino acids, peptides, and proteins), Alzheimer's disease, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcb21ab625b21b2290a47beed1218a2Test
https://doi.org/10.1002/iub.305Test