يعرض 1 - 10 نتائج من 34 نتيجة بحث عن '"Gene Products, tax"', وقت الاستعلام: 0.89s تنقيح النتائج
  1. 1
    The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape

    المؤلفون: Vandermeulen, Charlotte, O’grady, Tina, Wayet, Jerome, Galvan, Bartimee, Maseko, Sibusiso, Cherkaoui, Majid, Desbuleux, Alice, Coppin, Georges, Olivet, Julien, Ben Ameur, Lamya, Kataoka, Keisuke, Ogawa, Seishi, Hermine, Olivier, Marcais, Ambroise, Thiry, Marc, Mortreux, Franck, Calderwood, Michael, van Weyenbergh, Johan, Peloponese, Jean-Marie, Charloteaux, Benoit, van den Broeke, Anne, Hill, David E., Vidal, Marc, Dequiedt, Franck, Twizere, Jean-Claude

    المساهمون: GIGA [Université Liège], Université de Liège, Dana-Farber Cancer Institute [Boston], Harvard Medical School [Boston] (HMS), Laboratoire de biologie et modélisation de la cellule (LBMC UMR 5239), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Kyoto University, Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Rega Institute for Medical Research [Leuven, België], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Institut de Recherche en Infectiologie de Montpellier (IRIM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire de Liège (CHU-Liège), Institut Jules Bordet [Bruxelles], Faculté de Médecine [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), PELOPONESE, Jean-Marie

    المصدر: PLoS Pathogens
    PLoS Pathogens, 2021, 17 (9), pp.e1009919. ⟨10.1371/journal.ppat.1009919⟩
    PLoS Pathogens, Vol 17, Iss 9, p e1009919 (2021)
    P L o S Pathogens, 17 (9

    مصطلحات موضوعية: RNA viruses, Interaction Networks, Retroviridae Proteins, LEUKEMIA-VIRUS TYPE-1, RNA-binding proteins, Virologie générale, Pathology and Laboratory Medicine, Biochemistry, ACTIVATION, Jurkat Cells, White Blood Cells, Animal Cells, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Immunologie, BINDING, Medicine and Health Sciences, Leukemia-Lymphoma, Adult T-Cell, CD45, NETWORK, Biology (General), GENE-EXPRESSION, [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Parasitologie, Human T-lymphotropic virus 1, T Cells, Gene Products, tax, Genomics, PROTEIN INTERACTS, Nucleic acids, TRANSCRIPTION FACTORS, Basic-Leucine Zipper Transcription Factors, Oncology, Medical Microbiology, Viral Pathogens, Viruses, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Pathogens, Cellular Types, Biologie, Life Sciences & Biomedicine, Transcriptome Analysis, Research Article, QH301-705.5, RNA Splicing, Immune Cells, Immunology, Microbiology, Virology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Retroviruses, Genetics, Humans, RNA, Messenger, Microbial Pathogens, Molecular Biology, Science & Technology, Blood Cells, Biology and life sciences, Virologie médicale, RECOGNITION, Organisms, Biologie moléculaire, Cancers and Neoplasms, Proteins, Computational Biology, Htlv-1, Cell Biology, RC581-607, Splicing Factor U2AF, Genome Analysis, HTLV-I Infections, Alternative Splicing, HEK293 Cells, RNA processing, T-CELLS, RNA, Parasitology, Gene expression, Immunologic diseases. Allergy, Microbiologie et protistologie [bacteriol.virolog.mycolog.]

    وصف الملف: Electronic-eCollection; 1 full-text file(s): application/pdf; application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::949667cb1a24868a4354d9ff33baa466Test
    https://hal.science/hal-03400504/documentTest


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  2. 2
    The Tax oncogene enhances ELL incorporation into p300 and P-TEFb containing protein complexes to activate transcription

    المؤلفون: Temesgen D. Fufa, Cynthia A. Pise-Masison, Clay Wakano, Alfonso G. Fernandez, Jung S. Byun, Kevin Gardner

    المصدر: Biochemical and Biophysical Research Communications. 465:5-11

    مصطلحات موضوعية: Transcriptional Activation, Biophysics, Regulator, RNA polymerase II, Biochemistry, Jurkat Cells, Transactivation, Transcription (biology), Humans, Positive Transcriptional Elongation Factor B, RNA, Small Interfering, P-TEFb, Molecular Biology, Gene, Genetics, Human T-lymphotropic virus 1, Oncogene, biology, Chemistry, NF-kappa B, Gene Products, tax, Cell Biology, Ether-A-Go-Go Potassium Channels, Cell biology, Cell Transformation, Neoplastic, HEK293 Cells, Gene Expression Regulation, Host-Pathogen Interactions, biology.protein, Ectopic expression, RNA Polymerase II, Transcriptional Elongation Factors, E1A-Associated p300 Protein, Proto-Oncogene Proteins c-fos, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0f92c8c19cca17648f2e4c36521d09Test
    https://doi.org/10.1016/j.bbrc.2015.07.072Test


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  3. 3
    HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains

    المؤلفون: Yuri Shibata, Yasushi Saeki, Tsukasa Seya, Hiroyasu Nakano, Fuminori Tokunaga, Tatsuya Sawasaki, Kazuhiro Iwai, Ginga Komatsu, Jun-ichiro Inoue, Hirotaka Takahashi, Eiji Goto, Jin Gohda, Keiji Tanaka, Hiroyuki Oshiumi, Yuetsu Tanaka, Satoshi Inoue

    المصدر: PLoS Pathogens, Vol 13, Iss 1, p e1006162 (2017)
    PLoS Pathogens

    مصطلحات موضوعية: RNA viruses, 0301 basic medicine, IκB kinase, Pathology and Laboratory Medicine, Biochemistry, Jurkat cells, environment and public health, Deubiquitinating enzyme, Ligases, Jurkat Cells, White Blood Cells, Ubiquitin, Animal Cells, Medicine and Health Sciences, Small interfering RNAs, Post-Translational Modification, Phosphorylation, lcsh:QH301-705.5, Human T-lymphotropic virus 1, biology, T Cells, NF-kappa B, Chemical Reactions, Gene Products, tax, Recombination Reactions, I-kappa B Kinase, Precipitation Techniques, Enzymes, Cell biology, Nucleic acids, Chemistry, Medical Microbiology, Viral Pathogens, Physical Sciences, Viruses, Electrophoresis, Polyacrylamide Gel, Cellular Types, Pathogens, Signal Transduction, Research Article, lcsh:Immunologic diseases. Allergy, Immunoprecipitation, Immune Cells, Immunoblotting, Immunology, Molecular Probe Techniques, Real-Time Polymerase Chain Reaction, Transfection, Research and Analysis Methods, Microbiology, 03 medical and health sciences, Virology, Retroviruses, Genetics, Humans, Molecular Biology Techniques, Non-coding RNA, Microbial Pathogens, Molecular Biology, Transcription factor, Blood Cells, HEK 293 cells, Organisms, I-Kappa-B Kinase, Biology and Life Sciences, Proteins, Cell Biology, Htlv-1, HTLV-I Infections, Gene regulation, Enzyme Activation, HEK293 Cells, 030104 developmental biology, lcsh:Biology (General), Enzymology, biology.protein, RNA, Parasitology, Gene expression, lcsh:RC581-607

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b56cd611b6e9565448230967365383Test
    http://europepmc.org/articles/PMC5283754?pdf=renderTest


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  4. 4
    HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains

    المؤلفون: Xin Liu, Yoshinori Takahashi, Hua Cheng, Tong Ren, Thomas P. Loughran, Hong Gang Wang, Shao Cong Sun

    المصدر: Oncogene

    مصطلحات موضوعية: autophagy, Cancer Research, T-Lymphocytes, Green Fluorescent Proteins, Immunoblotting, IκB kinase, Jurkat cells, Article, Jurkat Cells, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Membrane Microdomains, 0302 clinical medicine, Cell Line, Tumor, Phagosomes, Genetics, Humans, Beclin1, Bif-1, Molecular Biology, Lipid raft, Cells, Cultured, Adaptor Proteins, Signal Transducing, 030304 developmental biology, lipid rafts, Human T-lymphotropic virus 1, 0303 health sciences, biology, IKK, Kinase, Autophagy, I-Kappa-B Kinase, Membrane Proteins, Signal transducing adaptor protein, Gene Products, tax, biology.organism_classification, I-kappa B Kinase, Cell biology, Microscopy, Fluorescence, 030220 oncology & carcinogenesis, Host-Pathogen Interactions, Mutation, Beclin-1, HTLV-1 Tax, Apoptosis Regulatory Proteins, Microtubule-Associated Proteins

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e9cad76fe67967e2b5c875a6d73861Test
    https://doi.org/10.1038/onc.2013.552Test


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  5. 5
    HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains

    المؤلفون: Zongping Xia, Chao Peng, Chong Wang, Qiong Zhang, Yuetsu Tanaka, Xiaoqing Zhang, Catherine C. L. Wong, Xiaotao Duan, Lin Hu, Ailing Wu, Wenying Long

    المصدر: PLoS Pathogens
    PLoS Pathogens, Vol 12, Iss 4, p e1005584 (2016)

    مصطلحات موضوعية: 0301 basic medicine, RNA viruses, cells, IκB kinase, Pathology and Laboratory Medicine, Jurkat cells, environment and public health, Biochemistry, Ligases, White Blood Cells, Gene Knockout Techniques, Jurkat Cells, Ubiquitin, Animal Cells, Tandem Mass Spectrometry, Medicine and Health Sciences, Post-Translational Modification, Phosphorylation, skin and connective tissue diseases, Polyubiquitin, lcsh:QH301-705.5, Chromatography, High Pressure Liquid, biology, T Cells, NF-kappa B, Gene Products, tax, Ubiquitin ligase, Enzymes, I-kappa B Kinase, Recombination-Based Assay, Medical Microbiology, Viral Pathogens, Viruses, 293T cells, Cell lines, Signal transduction, biological phenomena, cell phenomena, and immunity, Pathogens, Cellular Types, Biological cultures, Research Article, Signal Transduction, lcsh:Immunologic diseases. Allergy, Immune Cells, Ubiquitin-Protein Ligases, Immunology, Immunoblotting, Molecular Probe Techniques, Library Screening, Transfection, Microbiology, 03 medical and health sciences, Virology, Retroviruses, Genetics, Humans, Molecular Biology Techniques, Transcription factor, Microbial Pathogens, Molecular Biology, Molecular Biology Assays and Analysis Techniques, Blood Cells, 030102 biochemistry & molecular biology, HEK 293 cells, Ubiquitination, Organisms, Biology and Life Sciences, Proteins, Htlv-1, Cell Biology, NFKB1, Ubiquitin Ligases, HTLV-I Infections, Research and analysis methods, Enzyme Activation, enzymes and coenzymes (carbohydrates), 030104 developmental biology, HEK293 Cells, lcsh:Biology (General), biology.protein, Enzymology, Parasitology, lcsh:RC581-607

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad8ae31f8e94483ab5c26b64cd8289eTest
    https://u-ryukyu.repo.nii.ac.jp/records/2012291Test


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  6. 6
    Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB

    المؤلفون: Toshifumi Hara, Takayuki Takachi, Yosuke Motai, Yuetsu Tanaka, Masahiko Takahashi, Shuji Terai, Masahiro Fujii, Yutaka Aoyagi, Mariko Mizuguchi, Masaya Higuchi

    المصدر: Virus genes. 52(1)

    مصطلحات موضوعية: 0301 basic medicine, viruses, T-Lymphocytes, OX40 Ligand, Jurkat cells, 03 medical and health sciences, Jurkat Cells, Immune system, NF-kappa B p52 Subunit, hemic and lymphatic diseases, Virology, Genetics, medicine, Humans, education, Molecular Biology, education.field_of_study, Human T-lymphotropic virus 1, biology, RELB, Human T-lymphotropic virus 2, General Medicine, Gene Products, tax, biology.organism_classification, medicine.disease, Acquired immune system, OX40 ligand, Cell biology, Leukemia, 030104 developmental biology, HEK293 Cells

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76a4a38518ed71a927c3281dd6dc95bTest
    https://pubmed.ncbi.nlm.nih.gov/26739459Test


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  7. 7
    HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation

    المؤلفون: Chou-Zen Giam, Muhammad Atif Zahoor, Subha Philip, J. N. Mark Glover, Brian C. Schaefer, Tara Bowlin, Yik-Khuan Ho, Oliver John Semmes, Batsukh Dorjbal, Hsiu Ming Shih, Huijun Zhi

    المصدر: PLoS Pathogens, Vol 11, Iss 8, p e1005102 (2015)
    PLoS Pathogens

    مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, Ubiquitin-Protein Ligases, Immunoblotting, Immunology, Fluorescent Antibody Technique, Transfection, Polymerase Chain Reaction, Microbiology, Jurkat cells, Cell Line, Ubiquitin, Virology, Genetics, Humans, Molecular Biology, lcsh:QH301-705.5, biology, MAP kinase kinase kinase, Kinase, I-Kappa-B Kinase, Gene Products, tax, MAP Kinase Kinase Kinases, I-kappa B Kinase, Ubiquitin ligase, DNA-Binding Proteins, IκBα, Cell Transformation, Neoplastic, Biochemistry, lcsh:Biology (General), Gene Knockdown Techniques, biology.protein, Phosphorylation, Parasitology, lcsh:RC581-607, Signal Transduction, Research Article

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b67a266c0e30c949d53472487ddbfdTest
    http://europepmc.org/articles/PMC4540474?pdf=renderTest


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  8. 8
    Integrated molecular analysis of adult T cell leukemia/lymphoma

    المؤلفون: Yasunobu Nagata, Kensei Tobinai, June Takeda, Osamu Nureki, Yoko Kubuki, Shinichi Kotani, Yasushi Totoki, Yoshitaka Imaizumi, Satsuki Muto, Ryohei Ishii, Hiroko Tanaka, Hideaki Ogasawara, Hiroyuki Aburatani, Hidehiro Itonaga, Kengo Takeuchi, Natsuko Hama, Guangyong Ma, Tatsuhiro Shibata, Akifumi Takaori-Kondo, Ken Sasai, Hiromichi Suzuki, Masako Iwanaga, Genta Nagae, Masao Matsuoka, Akira Kitanaka, Kotaro Shide, Masashi Sanada, Yusuke Sato, Tsuyoshi Nakamaki, Sung-Soo Yoon, Hiromi Nakamura, Yusuke Shiozawa, Ken Ishiyama, Masakatsu Hishizawa, Toshiki Watanabe, Tetsuichi Yoshizato, Aiko Sato-Otsubo, Kazuya Shimoda, Hideki Makishima, Jun-ichirou Yasunaga, Tomonori Hidaka, Toshitaka Sato, Shuichi Miyawaki, Satoru Miyano, Kenzo Muramoto, Yuichi Shiraishi, Keisuke Kataoka, Takuro Kameda, Marina Penova, Teppei Shimamura, Seishi Ogawa, Yosaku Watatani, Takahisa Kawaguchi, Fumihiko Matsuda, Kisato Nosaka, Kenichi Chiba, Yasushi Miyazaki, Wataru Munakata, Kenichi Yoshida

    المصدر: Nature genetics. 47(11)

    مصطلحات موضوعية: Adult, DNA Copy Number Variations, T cell, T-Lymphocytes, T-cell leukemia, Molecular Sequence Data, Jurkat cells, Adult T-cell leukemia/lymphoma, Jurkat Cells, Genetics, medicine, T-cell lymphoma, Humans, Leukemia-Lymphoma, Adult T-Cell, Exome, Amino Acid Sequence, Human T-lymphotropic virus 1, biology, Sequence Homology, Amino Acid, Genome, Human, GATA3, Gene Products, tax, Sequence Analysis, DNA, DNA Methylation, biology.organism_classification, medicine.disease, Survival Analysis, BCL10, medicine.anatomical_structure, HEK293 Cells, Immunology, Host-Pathogen Interactions, Mutation, Cancer research, Transcriptome, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef8e537201dc9e9b6aae43ae2767e27Test
    https://pubmed.ncbi.nlm.nih.gov/26506901Test


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  9. 9
    High levels of cytoplasmic HTLV-1 Tax mutant proteins retain a Tax-NF-κB-CBP ternary complex in the cytoplasm

    المؤلفون: Kuan-Teh Jeang, Mordechai Aboud, Inbal Azran

    المصدر: Oncogene. 24:4521-4530

    مصطلحات موضوعية: Cytoplasm, Cancer Research, Mutant, Gene Expression, Biology, medicine.disease_cause, Jurkat Cells, NF-KappaB Inhibitor alpha, Gene expression, Genetics, medicine, Humans, Molecular Biology, Ternary complex, Cell Nucleus, Mutation, NF-kappa B, Transcription Factor RelA, Nuclear Proteins, Gene Products, tax, CREB-Binding Protein, Cyclic AMP-Dependent Protein Kinases, Molecular biology, Cell biology, medicine.anatomical_structure, Multiprotein Complexes, Trans-Activators, I-kappa B Proteins, Carcinogenesis, Nucleus, Nuclear localization sequence

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce410ba4f7b13263bddda9d07124de37Test
    https://doi.org/10.1038/sj.onc.1208645Test


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  10. 10
    Human T-cell Leukemia Virus-I Tax Oncoprotein Functionally Targets a Subnuclear Complex Involved in Cellular DNA Damage-Response

    المؤلفون: Eric Wong, Rodney C. Daniels, Abdelali Haoudi, Gary M. Kupfer, O. John Semmes

    المصدر: Journal of Biological Chemistry. 278:37736-37744

    مصطلحات موضوعية: G2 Phase, Genome instability, Cell cycle checkpoint, DNA damage, Immunoprecipitation, Protein Serine-Threonine Kinases, Biochemistry, Jurkat cells, Jurkat Cells, Humans, RNA, Small Interfering, Molecular Biology, Psychological repression, Genetics, biology, Intracellular Signaling Peptides and Proteins, Gene Products, tax, Cell Biology, Cell cycle, Phosphoproteins, Cell biology, Enzyme Activation, Checkpoint Kinase 2, Checkpoint Kinase 1, biology.protein, biological phenomena, cell phenomena, and immunity, Antibody, Carrier Proteins, Tumor Suppressor p53-Binding Protein 1, Protein Kinases, DNA Damage

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9c118f4909b3f72eae5a7486df913cTest
    https://doi.org/10.1074/jbc.m301649200Test


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