المؤلفون: Tamara S, Roman, Maren E, Cannon, Swarooparani, Vadlamudi, Martin L, Buchkovich, Brooke N, Wolford, Ryan P, Welch, Mario A, Morken, Grace J, Kwon, Arushi, Varshney, Romy, Kursawe, Ying, Wu, Anne U, Jackson, Michael R, Erdos, Johanna, Kuusisto, Markku, Laakso, Laura J, Scott, Michael, Boehnke, Francis S, Collins, Stephen C J, Parker, Michael L, Stitzel, Karen L, Mohlke

المصدر: Diabetes

مصطلحات موضوعية: Islets of Langerhans, Diabetes Mellitus, Type 2, Gene Expression Regulation, Insulin Secretion, Genetic Variation, Humans, Insulin, Genetics/Genomes/Proteomics/Metabolomics, Adenylyl Cyclases, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::82c9352dae5ee296ea0429986c7fe4dfTest
https://pubmed.ncbi.nlm.nih.gov/28684635Test

المؤلفون: J. Graessler, Ulf Smith, Marie-France Hivert, Antigone S. Dimas, Joshua W. Knowles, Stéphane Cauchi, Karen L. Mohlke, Michael Boehnke, David Meyre, Nicholas J. Wareham, Ci Song, Denis Rybin, Erik Ingelsson, Mario A. Morken, Anne U. Jackson, Michael R. Erdos, Peter Kovacs, Fahim Abbasi, Claudia Langenberg, Ke Hao, Andreas Pfeiffer, Thomas Quertemous, Lars Lind, Stefan R. Bornstein, Suzannah Bumpstead, Alena Stančáková, Lori L. Bonnycastle, Michael Stumvoll, Oluf Pedersen, Themistocles L. Assimes, Inês Barroso, Andrea Benazzo, Richard M. Watanabe, Magic Investigators, Josée Dupuis, Inga Prokopenko, Heather M. Stringham, Felicity Payne, Markku Laakso, Antje Fischer-Rosinsky, Francis S. Collins, Mark Walker, James B. Meigs, Torben Hansen, Peter Schwarz, Xia Yang, Yvonne Böttcher, Hans-Ulrich Häring, Anke Tönjes, Narisu Narisu, Cécile Lecoeur, Jaakko Tuomilehto, Reedik Mägi, Joachim Spranger, Amy J. Swift, Johanna Kuusisto, Jose C. Florez, Niels Grarup, Philippe Froguel, Vasiliki Lagou, Peter S. Chines, Mark I. McCarthy, Adam Barker, Trine Welløv Boesgaard, Richard N. Bergman

المصدر: Diabetes 63, 2158-2171 (2013)
Diabetes
Diabetes, vol 63, iss 6
Dimas, A S, Lagou, V, Barker, A, Knowles, J W, Magi, R, Hivert, M F, Benazzo, A, Rybin, D, Jackson, A U, Stringham, H M, Song, C, Fischer-Rosinsky, A, Boesgaard, T W, Grarup, N, Abbasi, F A, Assimes, T L, Hao, K, Yang, X, Lecoeur, C, Barroso, I, Bonnycastle, L L, Bottcher, Y, Bumpstead, S, Chines, P S, Erdos, M R, Graessler, J, Kovacs, P, Morken, M A, Narisu, N, Payne, F, Stancakova, A, Swift, A J, Tonjes, A, Bornstein, S R, Cauchi, S, Froguel, P, Meyre, D, Schwarz, P E H, Haring, H U, Smith, U, Boehnke, M, Bergman, R N, Collins, F S, Mohlke, K L, Tuomilehto, J, Quertemous, T, Lind, L, Hansen, T, Pedersen, O, Walker, M, Pfeiffer, A F H, Spranger, J, Stumvoll, M, Meigs, J B, Wareham, N J, Kuusisto, J, Laakso, M, Langenberg, C, Dupuis, J, Watanabe, R M, Florez, J C, Ingelsson, E, McCarthy, M I, Prokopenko, I & Investigators, M 2014, ' Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity ', Diabetes, vol. 63, no. 6, pp. 2158-2171 . https://doi.org/10.2337/db13-0949Test

مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, Insulin Resistance/genetics, Type 2 diabetes, Medical and Health Sciences, Endocrinology, 0302 clinical medicine, Gene Frequency, Risk Factors, Insulin-Secreting Cells, Insulin Secretion, 2.1 Biological and endogenous factors, Cluster Analysis, Insulin, Aetiology, 2. Zero hunger, Genetics, 0303 health sciences, SLC30A8, Medicine (all), Diabetes, Single Nucleotide, Diabetes and Metabolism, Diabetes Mellitus, Type 2/genetics, Female, Type 2, Insulin processing, medicine.medical_specialty, Insulin/metabolism, Quantitative Trait Loci, Socio-culturale, 030209 endocrinology & metabolism, Biology, Autoimmune Disease, Polymorphism, Single Nucleotide, MAGIC Investigators, Endocrinology & Metabolism, 03 medical and health sciences, Insulin-Secreting Cells/metabolism, Insulin resistance, Clinical Research, Alleles, Diabetes Mellitus, Type 2, Genetic Variation, Genome-Wide Association Study, Humans, Insulin Resistance, Transcription Factors, Genetic Predisposition to Disease, Internal Medicine, Diabetes mellitus, Internal medicine, Genetic model, Diabetes Mellitus, medicine, Transcription Factors/metabolism, Polymorphism, Metabolic and endocrine, 030304 developmental biology, Glycemic, Prevention, medicine.disease, biology.protein, Quantitative Trait Loci/genetics, TCF7L2

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec76408386665bb3ac65c80f7efd345Test
https://doi.org/10.2337/db13-0949Test

المؤلفون: Sarah L. Ruppert, Anna L. Gloyn, Amy J. Swift, Ilana Blech, Clesson Turner, James C. Mullikin, David Ng, Francis S. Collins, Leslie G. Biesecker, Matthew G. Rees, Mario A. Morken, Jennifer E. Below, Nicola L. Beer, Mark I. McCarthy

مصطلحات موضوعية: Nonsynonymous substitution, Male, Active Transport, Cell Nucleus, Mutation, Missense, Polymorphism, Single Nucleotide, Cohort Studies, Evolution, Molecular, Glucokinase, Missense mutation, Glucose homeostasis, Humans, Frameshift Mutation, Gene, Cellular localization, Triglycerides, Adaptor Proteins, Signal Transducing, Aged, Genetics, Glucokinase regulatory protein, biology, Genetic Variation, General Medicine, Exons, Middle Aged, Recombinant Proteins, Kinetics, Phenotype, Amino Acid Substitution, Codon, Nonsense, biology.protein, Female, Common disease-common variant, Research Article, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00dd9fe28756d4ed0f5935834f03659cTest
https://doi.org/10.1172/jci46425Test

المؤلفون: Peter Holmans, Udo Seedorf, Beverley M. Shields, Peter McGruffin, Arne Pfeufer, Steve Eyre, Nathalie J. Prescott, Michael Boehnke, Valentina Moskovina, Abiodun Onipinla, Leena Peltonen, Nadira Yuldasheva, Peter M. Nilsson, Valeria Romanazzi, Vincent Mooser, Göran Berglund, Alistair S. Hall, Dominic P. Kwiatkowski, Barry Widmer, Benjamin F. Voight, Stefania Bandinelli, Mark M. Iles, Sven Bergmann, Thomas Meitinger, James P. Boorman, Simonetta Guarrera, Nazneen Rahman, Murielle Bochud, Graham A. Hitman, Emma Keniry, Nelson B. Freimer, Richard Dobson, Francis S. Collins, Gerjan Navis, Jennifer L. Pointon, Richard N. Bergman, Ruth J. F. Loos, Roberto Lorbeer, Carolina A. Braga Marcano, Christian Gieger, Florian Ernst, Xin Yuan, Catherine Potter, Hazel E. Drummond, Allan H. Young, George Kirov, John F. Peden, Helen Stevens, David Clayton, Mattijs E. Numans, Katherine Gordon-Smith, Anne Farmer, Alastair Forbes, M. Khalid Mohiuddin, John A. Todd, Christopher G. Mathew, David A. Collier, Mark I. McCarthy, Francesca Bredin, Clive M. Onnie, Dan Davidson, Markus Perola, Pamela Whittaker, Yvonne T. van der Schouw, Rathi Ravindrarajan, I. C.A. Spencer, Teresa Ferreira, Nilesh J. Samani, Serge Hercberg, Gonçalo R. Abecasis, Christopher J. Groves, Nicholas John Craddock, Angela Döring, Edward G. Lakatta, Muminatou Jallow, Wendy L. McArdle, David Bentley, Susana Eyheramendy, Uwe Völker, Christopher Newton-Cheh, Jaspal S. Kooner, Hugh Watkins, Gavin Lucas, H. T. Leung, Marjo Ritta Jarvelin, Johanna Kuusisto, Wiek H. van Gilst, Wendy Thomson, Lou R. Cardon, Harold Snieder, Marju Orho-Melander, Patricia B. Munroe, Toshiko Tanaka, Jeffrey C. Barrett, Azhar Maqbool, Henry Völzke, John M. C. Connell, Elaine R. Nimmo, John R. B. Perry, Michael R. Stratton, Ralph McGinnis, Pekka Jousilahti, Michiel L. Bots, Ian Jones, Elizabeth Meech, Matthew A. Brown, Johannie Gungadoo, Jian'an Luan, Jilur Ghori, Richard J. Dixon, N. Charlotte Onland-Moret, Fulvio Ricceri, Anthony J. Balmforth, Catherine E. Todhunter, Inês Barroso, Sheila Bingham, Timo T. Valle, Fredrik O. Vannberg, Diana Zelenika, Stephen Sawcer, Anneli Pouta, David M. Evans, Cuno S. P. M. Uiterwaal, Pilar Galan, Georg Homuth, Hannah Donovan, David J. Conway, Paul Elliott, Alessandra Allione, Paul E. de Jong, Miles Parkes, Amy Chaney, John C. Chambers, Toby Johnson, Isaac Subirana, Vesela Gateva, Cathryn M. Lewis, Christopher J. O'Donnell, Hana Lango, David Schlessinger, Mark J. Caulfield, Thorsten Reffelmann, Jamie Barbour, Karen L. Mohlke, Sarah E. Hunt, Thilo Winzer, Frances M K Williams, Christopher Mathew, I. Wallace, Anuj Goel, Jaakko Tuomilehto, Louise V. Wain, Gabriel Crawford, Samantha L. Hider, Detelinea Grozeva, Elaine K. Green, Paul D. Gilbert, Peter S. Braund, Jaume Marrugat, Rainer Rettig, Pim van der Harst, Yik Ying Teo, Andrew P. Morris, Guiseppe Matullo, Serena Sanna, Cristen J. Willer, Suzannah Bumpstead, Niall C. Taylor, Jacques S. Beckmann, Pierre Meneton, Elin Org, Luigi Ferrucci, Doug Easton, Sheila Seal, Joanne M. Heward, Anne U. Jackson, Eleftheria Zeggini, Rachel M. Freathy, Maris Laan, Paul Wordsworth, Sarah Nutland, Kerstin Koch, Sian Ceasar, Anders Hamsten, Judith M. Hussey, Tariq Ahmad, Derek P. Jewell, Paul Scheet, Charlie W. Lees, C Farrar, Christopher Prowse, Markku Laakso, David St Clair, Kate Downes, Diederick E. Grobbee, Paul Burton, Simon C. Potter, Ian N. Bruce, Tim D. Spector, Anne Barton, H.-Erich Wichmann, Matthew J. Simmonds, David Hadley, Cecilia M. Lindgren, Gérard Waeber, Nigel W. Rayner, Melanie J. Newport, Manjinder S. Sandhu, Audrey Duncanson, Guangju Zhai, Simon Heath, Susan M. Ring, Alessandra Di Gregorio, Richard Williamson, Nicholas J. Wareham, Zhan Su, Olle Melander, John R. Thompson, Alexander Teumer, Sheila A. Fisher, Lachlan J. M. Coin, Leif Groop, Giovanni Tognoni, Amanda Elkin, Alan J. Silman, Jack Satsangi, Jane Worthington, Martin Farrall, John Webster, Niall Cardin, Neil Walker, Anna F. Dominiczak, Jeremy D. Sanderson, Damjan Vukcevic, Bryan Howie, Silvia Polidoro, Stephen G. Ball, Mark Tremelling, Stephen Newhouse, Stephen M. Schwartz, Lori L. Bonnycastle, Chris Wallace, Kijoung Song, Mario A. Morken, I. Nicol Ferrier, Beverley Barke, Paolo Vineis, Manuela Uda, Deborah P M Symmons, Emily J. Lyons, Mingzhan Xue, Timothy M. Frayling, Stephen C.L. Cough, David Withers, Adrian V. S. Hill, Suzanne Stevens, Jennifer Jolley, Marcus Dörr, Kirk A. Rockett, David B. Dunger, Mark Walker, Jayne A. Franklyn, Lisa Jones, David S. Siscovick, Ann-Christine Syvänen, Laura J. Scott, Morris J. Brown, Barbera Cant, Michael Inouye, Feng Zhang, Carlotta Sacerdote, Katherine S. Elliott, Jonathan Marchini, Peter Donnely, Michael John Owen, An Goris, Marcus Prembey, Andrew T. Hattersley, Gerome Breen, Marian L. Hamshere, Thomas Illig, Samer S. Najjar, Nicole Soranzo, Kay-Tee Khaw, Graham R. Walters, Willem H. Ouwehand, David P. Strachan, Martin D. Tobin, Alastair Compston, John C. Mansfield, David Altshuler, Salvatore Panico, Sekar Kathiresan, Dawn M. Waterworth, Michael N. Weedon, D. Timothy Bishop, Claire Bryan, Alexandra S. Knight, Kate L. Lee, Paul F. O'Reilly, Massimo Mangino, Michael Conlon O'Donovan, Jing Hua Zhao, Konstantinos A. Papadakis, Jennifer H. Barrett, Joanne Pereira-Gale, N J Timpson, Stephan B. Felix, Panos Deloukas, Nicholas A. Watkins, Anna-Liisa Hartikainen, Peter Vollenweider, Richard Jones, Anne Hinks, Fraser Cummings, Noha Lim, Linda A. Bradbury, Rhian G. William, Nita G. Forouhi, Roberto Eluosa, Ingeleif B. Hallgrimsdottir, Giorgio Sirugo, Robert Luben, Veikko Salomaa, Robert Clarke, Sally John, Ursula Everson, Emma King, Ivan Nikolov, Heather M. Stringham, Antony P. Attwood, Angelo Scuteri

المساهمون: Wellcome Trust Case Control Consortium, Burton, PR., Clayton, DG., Cardon, LR., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, DP., McCarthy, MI., Ouwehand, WH., Samani, NJ., Todd, JA., Donnelly, P., Barrett, JC., Davison, D., Easton, D., Evans, D., Leung, HT., Marchini, JL., Morris, AP., Spencer, IC., Tobin, MD., Attwood, AP., Boorman, JP., Cant, B., Everson, U., Hussey, JM., Jolley, JD., Knight, AS., Koch, K., Meech, E., Nutland, S., Prowse, CV., Stevens, HE., Taylor, NC., Walters, GR., Walker, NM., Watkins, NA., Winzer, T., Jones, RW., McArdle, WL., Ring, SM., Strachan, DP., Pembrey, M., Breen, G., St Clair, D., Caesar, S., Gordon-Smith, K., Jones, L., Fraser, C., Green, EK., Grozeva, D., Hamshere, ML., Holmans, PA., Jones, IR., Kirov, G., Moskvina, V., Nikolov, I., O'Donovan, MC., Owen, MJ., Collier, DA., Elkin, A., Farmer, A., Williamson, R., McGuffin, P., Young, AH., Ferrier, IN., Ball, SG., Balmforth, AJ., Barrett, JH., Bishop, DT., Iles, MM., Maqbool, A., Yuldasheva, N., Hall, AS., Braund, PS., Dixon, RJ., Mangino, M., Stevens, S., Thompson, JR., Bredin, F., Tremelling, M., Parkes, M., Drummond, H., Lees, CW., Nimmo, ER., Satsangi, J., Fisher, SA., Forbes, A., Lewis, CM., Onnie, CM., Prescott, NJ., Sanderson, J., Mathew, CG., Barbour, J., Mohiuddin, MK., Todhunter, CE., Mansfield, JC., Ahmad, T., Cummings, FR., Jewell, DP., Webster, J., Brown, MJ., Lathrop, GM., Connell, J., Dominiczak, A., Braga Marcano, CA., Burke, B., Dobson, R., Gungadoo, J., Lee, KL., Munroe, PB., Newhouse, SJ., Onipinla, A., Wallace, I., Xue, M., Caulfield, M., Farrall, M., Barton, A., Bruce, IN., Donovan, H., Eyre, S., Gilbert, PD., Hider, SL., Hinks, AM., John, SL., Potter, C., Silman, AJ., Symmons, DP., Thomson, W., Worthington, J., Dunger, DB., Widmer, B., Frayling, TM., Freathy, RM., Lango, H., Perry, JR., Shields, BM., Weedon, MN., Hattersley, AT., Hitman, GA., Walker, M., Elliott, KS., Groves, CJ., Lindgren, CM., Rayner, NW., Timpson, NJ., Zeggini, E., Newport, M., Sirugo, G., Lyons, E., Vannberg, F., Hill, AV., Bradbury, LA., Farrar, C., Pointon, JJ., Wordsworth, P., Brown, MA., Franklyn, JA., Heward, JM., Simmonds, MJ., Gough, SC., Seal, S., Stratton, MR., Rahman, N., Ban, M., Goris, A., Sawcer, SJ., Compston, A., Conway, D., Jallow, M., Rockett, KA., Bryan, C., Bumpstead, SJ., Chaney, A., Downes, K., Ghori, J., Gwilliam, R., Hunt, SE., Inouye, M., Keniry, A., King, E., McGinnis, R., Potter, S., Ravindrarajah, R., Whittaker, P., Withers, D., Cardin, NJ., Ferreira, T., Pereira-Gale, J., Hallgrimsdóttir, IB., Howie, BN., Su, Z., Teo, YY., Vukcevic, D., Bentley, D., Life Course Epidemiology (LCE), Cardiovascular Centre (CVC), Lifestyle Medicine (LM), Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), Medical Research Council (MRC)

المصدر: Nature Genetics, vol. 41, no. 6, pp. 666-676
Nature Genetics; Vol 41
Nature Genetics, 41(6), 666-676. Nature Publishing Group
Nature Genetics, 41, 666. Nature Publishing Group
Newton-Cheh, C, Johnson, T, Gateva, V, Tobin, M D, Bochud, M, Coin, L, Najjar, S S, Zhao, J H, Heath, S C, Eyheramendy, S, Papadakis, K, Voight, B F, Scott, L J, Zhang, F, Farrall, M, Tanaka, T, Wallace, C, Chambers, J C, Khaw, K-T, Nilsson, P, van der Harst, P, Polidoro, S, Grobbee, D E, Onland-Moret, N C, Bots, M L, Wain, L V, Elliott, K S, Teumer, A, Luan, J, Lucas, G, Kuusisto, J, Burton, P R, Hadley, D, McArdle, W L, Brown, M, Dominiczak, A, Newhouse, S J, Samani, N J, Webster, J, Zeggini, E, Beckmann, J S, Bergmann, S, Lim, N, Song, K, Vollenweider, P, Waeber, G, Waterworth, D M, Yuan, X & Groop, L & Orho-Melander, M 2009, ' Genome-wide association study identifies eight loci associated with blood pressure ', Nature Genetics, vol. 41, no. 6, pp. 666-76 . https://doi.org/10.1038/ng.361Test
Nature genetics
Nature Genetics

مصطلحات موضوعية: Hemodynamics, Genome-wide association study, Blood Pressure, 030204 cardiovascular system & hematology, 0302 clinical medicine, Diastole, 11 Medical and Health Sciences, POPULATION, Genetics, Genetics & Heredity, RISK, 0303 health sciences, education.field_of_study, Econometric and Statistical Methods: General, CELL-DIFFERENTIATION, biology, Intracellular Signaling Peptides and Proteins, Chromosome Mapping, Steroid 17-alpha-Hydroxylase, COMMON VARIANTS, 3. Good health, DNA-Binding Proteins, Europe, Cardiovascular Diseases, PUBLIC-HEALTH, BARTTERS-SYNDROME, Blood Pressure/genetics, Cardiovascular Diseases/genetics, Cardiovascular Diseases/physiopathology, Cytochrome P-450 CYP1A2/genetics, DNA-Binding Proteins/genetics, Diastole/genetics, European Continental Ancestry Group/genetics, Fibroblast Growth Factor 5/genetics, Genetic Variation, Genome-Wide Association Study, Humans, India, Methylenetetrahydrofolate Reductase (NADPH2)/genetics, Open Reading Frames/genetics, Phospholipase C delta/genetics, Polymorphism, Single Nucleotide, Proteins/genetics, Steroid 17-alpha-Hydroxylase/genetics, Systole/genetics, Wellcome Trust Case Control Consortium, Life Sciences & Biomedicine, hypertension, Fibroblast Growth Factor 5, Systole, Population, European Continental Ancestry Group, METHYLENETETRAHYDROFOLATE REDUCTASE GENE, Single-nucleotide polymorphism, LOW-RENIN HYPERTENSION, White People, Article, 03 medical and health sciences, Open Reading Frames, Fibroblast growth factor-5, Cytochrome P-450 CYP1A2, Geneeskunde(GENK), education, Methylenetetrahydrofolate Reductase (NADPH2), Adaptor Proteins, Signal Transducing, 030304 developmental biology, Genetic association, genome-wide association, Science & Technology, MUTATIONS, Proteins, 06 Biological Sciences, POLYMORPHISM, Blood pressure, Methylenetetrahydrofolate reductase, biology.protein, biology.gene, Phospholipase C delta, Developmental Biology

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c788afaa54ff3f80dee7ce33e23426eTest
https://hdl.handle.net/11370/ce10605f-7633-4606-bbc8-ecbd9d73092dTest

المؤلفون: Ryan M. McDaniell, Huntington F. Willard, Katerina S. Kucera, Francis S. Collins, Gregory E. Crawford, Terrence S. Furey, Lingyun Song, Alan P. Boyle, Jason D. Lieb, Vishwanath R. Iyer, Damian Keefe, Anna Battenhouse, Mario A. Morken, Ewan Birney, Zheng Liu, Michael R. Erdos, Laura J. Scott, Bum Kyu Lee

المصدر: Science

مصطلحات موضوعية: Male, CCCTC-Binding Factor, Chromatin Immunoprecipitation, Black People, Biology, Polymorphism, Single Nucleotide, White People, Article, Cell Line, Nuclear Family, X Chromosome Inactivation, Genetic variation, Chromosomes, Human, Deoxyribonuclease I, Humans, Regulatory Elements, Transcriptional, Allele, Transcription factor, Alleles, Genetics, Chromosomes, Human, X, Multidisciplinary, Binding Sites, Chromosome, Genetic Variation, Sequence Analysis, DNA, Phenotype, Chromatin, Repressor Proteins, Gene Expression Regulation, Human genome, Female, Chromatin immunoprecipitation, Protein Binding, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5953ae718fdd2cb686dd0ac6f954b0Test
https://pubmed.ncbi.nlm.nih.gov/20299549Test

المؤلفون: François Pattou, Thomas Sparsø, Eleftheria Zeggini, Michael N. Weedon, J. Graessler, Mandy van Hoek, Suzette J. Bielinski, Amy J. Swift, David S. Siscovick, Michael R. Erdos, Kenneth Rice, Nabila Bouatia-Naji, Benjamin F. Voight, Wolfgang Rathmann, Jarred B. McAteer, Caroline S. Fox, Kari Stefansson, Vincent Mooser, Philippe Froguel, Gordon H. Williams, Mike Sampson, Annelli Sandbæk, Jeffrey R. O'Connell, Stefan R. Bornstein, Robert Sladek, Andrew D. Morris, Torben Jørgensen, Suzannah Bumpstead, Ruth E. Pakyz, James B. Meigs, Denis Rybin, Peter Vollenweider, Valle Tt, Andrew T. Hattersley, Amélie Bonnefond, Knut Krohn, Kijoung Song, Erik Ingelsson, Mario A. Morken, Laura J. Scott, Richard M. Watanabe, Eric J.G. Sijbrands, David Altshuler, Harald Grallert, Vladimir Mayor, Yii-Der Ida Chen, Heather M. Stringham, Bruce M. Psaty, Andrew B. Singleton, Nicole L. Glazer, Peter Schwarz, Jaakko Tuomilehto, Mathieu Firmann, Yvonne Böttcher, Knut Borch-Johnsen, Josée Dupuis, Unnur Thorsteinsdottir, Thomas A. Buchanan, Avan Aihie Sayer, Inga Prokopenko, Thomas Illig, Inês Barroso, Aroon D. Hingorani, Daniel S. Pearson, Luigi Ferrucci, Anna Köttgen, H.-Erich Wichmann, Peter Shrader, Yurii S. Aulchenko, Lu Qi, Olivier Le Bacquer, Eric J. Brunner, Meena Kumari, Karen L. Mohlke, Valgerdur Steinthorsdottir, Laura Pascoe, Lori L. Bonnycastle, Francis S. Collins, Jérôme Delplanque, Guillaume Charpentier, Michael Stumvoll, Mark O. Goodarzi, Felicity Payne, Ruth J. F. Loos, Richard N. Bergman, Gudmar Thorleifsson, Beverley Balkau, Jing Hua Zhao, Timothy M. Frayling, Josephine M. Egan, Kristin Ardlie, Stephen J. Sharp, Jalal Taneera, Mark Walker, W. H. Linda Kao, Nicholas L. Smith, Niels Grarup, Nita G. Forouhi, Oluf Pedersen, Cécile Lecoeur, Andrew Walley, Ann-Christine Syvänen, Eric Boerwinkle, Toby Johnson, Camilla H. Andreasen, Jian Anluan, Dawn M. Waterworth, Toshiko Tanaka, Braxton D. Mitchell, Alisa K. Manning, James S. Pankow, Valeriya Lyssenko, Mika Kivimäki, David Couper, Alex S. F. Doney, Nicholas J. Wareham, Tiinamaija Tuomi, Johanna Kuusisto, Torben Hansen, Christine Cavalcanti-Proença, Richa Saxena, Markku Laakso, James F. Wilson, Bo Isomaa, Marilyn C. Cornelis, David Meyre, Anne U. Jackson, Holly E. Syddall, Alan R. Shuldiner, Michael Boehnke, Peter M. Nilsson, Gabriel Crawford, Claudia Langenberg, Jerome I. Rotter, Peter S. Chines, Cyrus Cooper, Peter Kovacs, Torsten Lauritzen, Christian Dina, Gerard Waeber, Man Li, Anke Tönjes, Narisu Narisu, Jose C. Florez, David M. Nathan, Leif Groop, Claire Levy-Marchal, Cornelia M. van Duijn, Mark I. McCarthy, Frank B. Hu, Trine Welløv Boesgaard, Colin N. Apalmer, Michael Marmot

المساهمون: GIANT consortium, MAGIC investigators, Ophthalmology, Internal Medicine, Epidemiology

المصدر: Saxena, R, Hivert, M-F, Langenberg, C, Tanaka, T, Pankow, J S, Vollenweider, P, Lyssenko, V, Bouatia-Naji, N, Dupuis, J, Jackson, A U, Kao, W H L, Li, M, Glazer, N L, Manning, A K, Luan, J, Stringham, H M, Prokopenko, I, Johnson, T, Grarup, N, Boesgaard, T W, Lecoeur, C, Shrader, P, O'Connell, J, Ingelsson, E, Couper, D J, Rice, K, Song, K, Andreasen, C H, Dina, C, Köttgen, A, Le Bacquer, O, Pattou, F, Taneera, J, Steinthorsdottir, V, Rybin, D, Ardlie, K, Sampson, M, Qi, L, van Hoek, M, Weedon, M N, Aulchenko, Y S, Voight, B F, Grallert, H, Balkau, B, Bergman, R N, Bielinski, S J, Bonnefond, A, Bonnycastle, L L, Lauritzen, T, Sandbaek, A & GIANT Consortium 2010, ' Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge ', Nature Genetics, vol. 42, no. 2, pp. 142-8 . https://doi.org/10.1038/ng.521Test
Nature genetics
Saxena, R, Hivert, M-F, Langenberg, C, Tanaka, T, Pankow, J S, Vollenweider, P, Lyssenko, V, Bouatia-Naji, N, Dupuis, J, Jackson, A U, Kao, W H L, Li, M, Glazer, N L, Manning, A K, Luan, J, Stringham, H M, Prokopenko, I, Johnson, T, Grarup, N, Boesgaard, T W, Lecoeur, C, Shrader, P, O'Connell, J, Ingelsson, E, Couper, D J, Rice, K, Song, K, Andreasen, C H, Dina, C, Koettgen, A, Le Bacquer, O, Pattou, F, Taneera, J, Steinthorsdottir, V, Rybin, D, Ardlie, K, Sampson, M, Qi, L, van Hoek, M, Weedon, M N, Aulchenko, Y S, Voight, B F, Grallert, H, Balkau, B, Bergman, R N, Bielinski, S J, Bonnefond, A, Bonnycastle, L L & Wilson, J F & Morris, A 2010, ' Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge ', Nature Genetics, vol. 42, no. 2, pp. 142-U75 . https://doi.org/10.1038/ng.521Test
Saxena, R, Hivert, M-F, Langenberg, C, Tanaka, T, Pankow, J S, Vollenweider, P, Lyssenko, V, Bouatia-Naji, N, Dupuis, J, Jackson, A U, Kao, W H L, Li, M, Glazer, N L, Manning, A K, Luan, J, Stringham, H M, Prokopenko, I, Johnson, T, Grarup, N, Boesgaard, T W, Lecoeur, C, Shrader, P, O'Connell, J, Ingelsson, E, Couper, D J, Rice, K, Song, K, Andreasen, C H, Dina, C, Köttgen, A, Le Bacquer, O, Pattou, F, Taneera, J, Steinthorsdottir, V, Rybin, D, Ardlie, K, Sampson, M, Qi, L, van Hoek, M, Weedon, M N, Aulchenko, Y S, Voight, B F, Grallert, H, Balkau, B, Bergman, R N, Bielinski, S J, Bonnefond, A, Bonnycastle, L L, Borch-Johnsen, K, Böttcher, Y, Brunner, E, Buchanan, T A, Bumpstead, S J, Cavalcanti-Proença, C, Charpentier, G, Chen, Y-D I, Chines, P S, Collins, F S, Cornelis, M, J Crawford, G, Delplanque, J, Doney, A, Egan, J M, Erdos, M R, Firmann, M, Forouhi, N G, Fox, C S, Goodarzi, M O, Graessler, J, Hingorani, A, Isomaa, B, Jørgensen, T, Kivimaki, M, Kovacs, P, Krohn, K, Kumari, M, Lauritzen, T, Lévy-Marchal, C, Mayor, V, McAteer, J B, Meyre, D, Mitchell, B D, Mohlke, K L, Morken, M A, Narisu, N, Palmer, C N A, Pakyz, R, Pascoe, L, Payne, F, Pearson, D, Rathmann, W, Sandbaek, A, Sayer, A A, Scott, L J, Sharp, S J, Sijbrands, E, Singleton, A, Siscovick, D S, Smith, N L, Sparsø, T, Swift, A J, Syddall, H, Thorleifsson, G, Tönjes, A, Tuomi, T, Tuomilehto, J, Valle, T T, Waeber, G, Walley, A, Waterworth, D M, Zeggini, E, Zhao, J H, Illig, T, Wichmann, H E, Wilson, J F, van Duijn, C, Hu, F B, Morris, A D, Frayling, T M, Hattersley, A T, Thorsteinsdottir, U, Stefansson, K, Nilsson, P, Syvänen, A-C, Shuldiner, A R, Walker, M, Bornstein, S R, Schwarz, P, Williams, G H, Nathan, D M, Kuusisto, J, Laakso, M, Cooper, C, Marmot, M, Ferrucci, L, Mooser, V, Stumvoll, M, Loos, R J F, Altshuler, D, Psaty, B M, Rotter, J I, Boerwinkle, E, Hansen, T, Pedersen, O, Florez, J C, McCarthy, M I, Boehnke, M, Barroso, I, Sladek, R, Froguel, P, Meigs, J B, Groop, L, Wareham, N J & Watanabe, R M 2010, ' Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge ', Nature Genetics, vol. 42, no. 2, pp. 142-8 . https://doi.org/10.1038/ng.521Test
Nature Genetics, vol. 42, no. 2, pp. 142-148
Nature Genetics; Vol 42
Nature Genetics
Nature Genetics, 42(2), 142-U75. Nature Publishing Group

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https://pure.au.dk/portal/da/publications/genetic-variation-in-gipr-influences-the-glucose-and-insulin-responses-to-an-oral-glucose-challengeTest(0b6bb44f-2d27-4aef-8313-cfafcdc8f39d).html

المؤلفون: Richard N. Bergman, Derrick A Bennett, Cristen J. Willer, Richard M. Watanabe, Nicholas J. Timpson, Karen L. Mohlke, Robert Clarke, Francis S. Collins, Laura J. Scott, Antonio Cao, Angelo Scuteri, Alan R. Shuldiner, Antonella Mulas, G. Mark Lathrop, Andrea Maschio, Samer S. Najjar, Diana Zelenika, Serena Sanna, William L. Duren, Michael Boehnke, Jaakko Tuomilehto, Pilar Galan, James B. Strait, Heather M. Stringham, Debbie A Lawlor, Rory Collins, Ramaiah Nagaraja, Anne U. Jackson, Yun Li, Jouko Sundvall, Sarah Parish, Manuela Uda, George Davey-Smith, Giuseppe Albai, Paul Scheet, Shah Ebrahim, Haiqing Shen, David Schlessinger, Pierre Meneton, Lori L. Bonnycastle, Simon Heath, Gonçalo R. Abecasis, Mario A. Morken, Wei-Min Chen, Edward G. Lakatta, Amy J. Swift, Yoav Ben-Shlomo, Narisu Narisu, Fabio Busonero, Serge Hercberg

المصدر: Nature genetics. 40(2)

مصطلحات موضوعية: medicine.medical_specialty, Apolipoprotein B, Coronary Artery Disease, 030204 cardiovascular system & hematology, Polymorphism, Single Nucleotide, Article, Cohort Studies, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Gene Frequency, Risk Factors, Internal medicine, Genetics, medicine, Humans, Computer Simulation, Allele frequency, Alleles, Triglycerides, 030304 developmental biology, Probability, 0303 health sciences, Likelihood Functions, biology, Cholesterol, Genome, Human, PCSK9, Haplotype, Cholesterol, HDL, Genetic Variation, Cholesterol, LDL, Lipids, Markov Chains, 3. Good health, Endocrinology, chemistry, Haplotypes, ABCA1, Case-Control Studies, LDL receptor, biology.protein, lipids (amino acids, peptides, and proteins), Lipoprotein

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https://pubmed.ncbi.nlm.nih.gov/18227868Test