المؤلفون: J. Graessler, Ulf Smith, Marie-France Hivert, Antigone S. Dimas, Joshua W. Knowles, Stéphane Cauchi, Karen L. Mohlke, Michael Boehnke, David Meyre, Nicholas J. Wareham, Ci Song, Denis Rybin, Erik Ingelsson, Mario A. Morken, Anne U. Jackson, Michael R. Erdos, Peter Kovacs, Fahim Abbasi, Claudia Langenberg, Ke Hao, Andreas Pfeiffer, Thomas Quertemous, Lars Lind, Stefan R. Bornstein, Suzannah Bumpstead, Alena Stančáková, Lori L. Bonnycastle, Michael Stumvoll, Oluf Pedersen, Themistocles L. Assimes, Inês Barroso, Andrea Benazzo, Richard M. Watanabe, Magic Investigators, Josée Dupuis, Inga Prokopenko, Heather M. Stringham, Felicity Payne, Markku Laakso, Antje Fischer-Rosinsky, Francis S. Collins, Mark Walker, James B. Meigs, Torben Hansen, Peter Schwarz, Xia Yang, Yvonne Böttcher, Hans-Ulrich Häring, Anke Tönjes, Narisu Narisu, Cécile Lecoeur, Jaakko Tuomilehto, Reedik Mägi, Joachim Spranger, Amy J. Swift, Johanna Kuusisto, Jose C. Florez, Niels Grarup, Philippe Froguel, Vasiliki Lagou, Peter S. Chines, Mark I. McCarthy, Adam Barker, Trine Welløv Boesgaard, Richard N. Bergman

المصدر: Diabetes 63, 2158-2171 (2013)
Diabetes
Diabetes, vol 63, iss 6
Dimas, A S, Lagou, V, Barker, A, Knowles, J W, Magi, R, Hivert, M F, Benazzo, A, Rybin, D, Jackson, A U, Stringham, H M, Song, C, Fischer-Rosinsky, A, Boesgaard, T W, Grarup, N, Abbasi, F A, Assimes, T L, Hao, K, Yang, X, Lecoeur, C, Barroso, I, Bonnycastle, L L, Bottcher, Y, Bumpstead, S, Chines, P S, Erdos, M R, Graessler, J, Kovacs, P, Morken, M A, Narisu, N, Payne, F, Stancakova, A, Swift, A J, Tonjes, A, Bornstein, S R, Cauchi, S, Froguel, P, Meyre, D, Schwarz, P E H, Haring, H U, Smith, U, Boehnke, M, Bergman, R N, Collins, F S, Mohlke, K L, Tuomilehto, J, Quertemous, T, Lind, L, Hansen, T, Pedersen, O, Walker, M, Pfeiffer, A F H, Spranger, J, Stumvoll, M, Meigs, J B, Wareham, N J, Kuusisto, J, Laakso, M, Langenberg, C, Dupuis, J, Watanabe, R M, Florez, J C, Ingelsson, E, McCarthy, M I, Prokopenko, I & Investigators, M 2014, ' Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity ', Diabetes, vol. 63, no. 6, pp. 2158-2171 . https://doi.org/10.2337/db13-0949Test

مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, Insulin Resistance/genetics, Type 2 diabetes, Medical and Health Sciences, Endocrinology, 0302 clinical medicine, Gene Frequency, Risk Factors, Insulin-Secreting Cells, Insulin Secretion, 2.1 Biological and endogenous factors, Cluster Analysis, Insulin, Aetiology, 2. Zero hunger, Genetics, 0303 health sciences, SLC30A8, Medicine (all), Diabetes, Single Nucleotide, Diabetes and Metabolism, Diabetes Mellitus, Type 2/genetics, Female, Type 2, Insulin processing, medicine.medical_specialty, Insulin/metabolism, Quantitative Trait Loci, Socio-culturale, 030209 endocrinology & metabolism, Biology, Autoimmune Disease, Polymorphism, Single Nucleotide, MAGIC Investigators, Endocrinology & Metabolism, 03 medical and health sciences, Insulin-Secreting Cells/metabolism, Insulin resistance, Clinical Research, Alleles, Diabetes Mellitus, Type 2, Genetic Variation, Genome-Wide Association Study, Humans, Insulin Resistance, Transcription Factors, Genetic Predisposition to Disease, Internal Medicine, Diabetes mellitus, Internal medicine, Genetic model, Diabetes Mellitus, medicine, Transcription Factors/metabolism, Polymorphism, Metabolic and endocrine, 030304 developmental biology, Glycemic, Prevention, medicine.disease, biology.protein, Quantitative Trait Loci/genetics, TCF7L2

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https://doi.org/10.2337/db13-0949Test

المؤلفون: Claudia Lamina, Dawn M. Waterworth, Ramachandran S. Vasan, Alan R. Sinaiko, Jorma Viikari, Alena Stančáková, Nita G. Forouhi, Leo-Pekka Lyytikäinen, Chloe Y Y Cheung, Torben Hansen, Bernhard Paulweber, Ying Wu, Christie M. Ballantyne, Jaakko Tuomilehto, Karen S.L. Lam, Jussi Paananen, James B. Meigs, Jing Hua Zhao, Francis S. Collins, Hans U. Häring, Marie-France Hivert, Joshua W. Knowles, Zari Dastani, Andrew T. Hattersley, Ele Ferrannini, Ching-Ti Liu, Sarah Buxbaum, Mika Kähönen, Peter Henneman, Aurelian Bidulescu, Michael Boehnke, Ruth J. F. Loos, Fatiha el Bouazzaoui, Ulf Smith, Tim D. Spector, Josée Dupuis, Weijia Xie, Thomas Quertermous, Robert K. Semple, Lyudmyla Kedenko, John J. Nolan, Andrew D. Morris, Anne U. Jackson, Cornelia M. van Duijn, Ko Willems van Dijk, Markku Laakso, Robert A. Scott, Na Zhu, Oluf Pedersen, Terho Lehtimäki, Claudia Langenberg, Ke Hao, Christopher J. Gillson, Olli T. Raitakari, Mark I. McCarthy, Florian Kronenberg, Jaeyoung Hong, James S. Pankow, Debbie A Lawlor, Nicholas J. Wareham, Karen L. Mohlke, Timothy M. Frayling, Tanya M. Teslovich, Sandra H. Dunn, Alessandro Doria, Cecilia M. Lindgren, Richard N. Bergman, Johanna Kuusisto, Hanieh Yaghootkar, Liling Warren, Stefan Gustafsson, Erik Ingelsson, Colin N. A. Palmer, Mark Walker, Themistocles L. Assimes, J. Brent Richards

المساهمون: Epidemiology, Medical Microbiology & Infectious Diseases

المصدر: Diabetes, 62(10), 3589-3598
Yaghootkar, H, Lamina, C, Scott, R A, Dastani, Z, Hivert, M F, Warren, L L, Stancakova, A, Buxbaum, S G, Lyytikaeinen, L P, Henneman, P, Wu, Y, Cheung, C Y Y, Pankow, J S, Jackson, A U, Gustafsson, S, Zhao, J H, Ballantyne, C M, Xie, W J, Bergman, R N, Boehnke, M, el Bouazzaoui, F, Collins, F S, Dunn, S H, Dupuis, J, Forouhi, N G, Gillson, C, Hattersley, A T, Hong, J Y, Kaehoenen, M, Kuusisto, J, Kedenko, L, Kronenberg, F, Doria, A, Assimes, T L, Ferrannini, E, Hansen, T, Hao, K, Haering, H, Knowles, J W, Lindgren, C M, Nolan, J J, Paananen, J, Pedersen, O, Quertermous, T, Smith, U, Lehtimaeki, T, Liu, C T, Loos, R J F, McCarthy, M I, Morris, A D, Vasan, R S, Spector, T D, Teslovich, T M, Tuomilehto, J, van Dijk, K W, Viikari, J S, Zhu, N, Langenberg, C, Ingelsson, E, Semple, R K, Sinaiko, A R, Palmer, C N A, Walker, M, Lam, K S L, Paulweber, B, Mohlke, K L, van Duijn, C, Raitakari, O T, Bidulescu, A, Wareham, N J, Laakso, M, Waterworth, D M, Lawlor, D A, Meigs, J B, Richards, J B, Frayling, T M, Consortium, G & Consortium, R 2013, ' Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes ', Diabetes, vol. 62, pp. 3589-3598 . https://doi.org/10.2337/db13-0128Test
Diabetes
Yaghootkar, H, Lamina, C, Scott, R A, Dastani, Z, Hivert, M F, Warren, L L, Stancáková, A, Buxbaum, S G, Lyytikäinen, L P, Henneman, P, Wu, Y, Cheung, C Y Y, Pankow, J S, Jackson, A U, Gustafsson, S, Zhao, J H, Ballantyne, C M, Xie, W, Bergman, R N, Boehnke, M, El Bouazzaoui, F, Collins, F S, Dunn, S H, Dupuis, J, Forouhi, N G, Gillson, C, Hattersley, A T, Hong, J, Kähönen, M, Kuusisto, J, Kedenko, L, Kronenberg, F, Doria, A, Assimes, T L, Ferrannini, E, Hansen, T, Hao, K, Häring, H, Knowles, J W, Lindgren, C M, Nolan, J J, Paananen, J, Pedersen, O, Quertermous, T, Smith, U, Lehtimäki, T, Liu, C T, Loos, R J F, McCarthy, M I, Morris, A D, Vasan, R S, Spector, T D, Teslovich, T M, Tuomilehto, J, Van Dijk, K W, Viikari, J S, Zhu, N, Langenberg, C, Ingelsson, E, Semple, R K, Sinaiko, A R, Palmer, C N A, Walker, M, Lam, K S L, Paulweber, B, Mohlke, K L, Van Duijn, C, Raitakari, O T, Bidulescu, A, Wareham, N J, Laakso, M, Waterworth, D M, Lawlor, D A, Meig, J B, Richards, J B & Frayling, T M 2013, ' Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes ', Diabetes, vol. 62, no. 10, pp. 3589-3598 . https://doi.org/10.2337/db13-0128Test
Diabetes, 62(10), 3589-3598. American Diabetes Association Inc.

مصطلحات موضوعية: Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Type 2 diabetes, ADIPOQ Gene, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, MOLECULAR-WEIGHT ADIPONECTIN GREATER-THAN-G PLASMA ADIPONECTIN ADIPOSE-TISSUE ASSOCIATION ANALYSES METABOLIC PROFILE GENETIC-VARIANTS SUPPRESSION TEST GLYCEMIC TRAITS OBESE WOMEN, 0302 clinical medicine, Insulin resistance, SDG 3 - Good Health and Well-being, Diabetes mellitus, Internal medicine, Mendelian randomization, Odds Ratio, Internal Medicine, medicine, Humans, Genetic Predisposition to Disease, Original Research, 030304 developmental biology, 0303 health sciences, Adiponectin, Genetic Variation, Genetics/Genomes/Proteomics/Metabolomics, Mendelian Randomization Analysis, Odds ratio, medicine.disease, 3. Good health, Endocrinology, Diabetes Mellitus, Type 2, Regression Analysis, Female, Insulin Resistance

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https://ora.ox.ac.uk/objects/uuid:fd376590-520a-44d4-a377-1d5ba7bc4b0cTest

المؤلفون: Núria Sala, Nina Roswall, Tilman Kühn, Larraitz Arriola, Dorota Pasko, Elio Riboli, Mark I. McCarthy, Afshan Siddiq, María José Sánchez, Luca A. Lotta, Francesca L. Crowe, Timothy J. Key, Peter M. Nilsson, Anne Tjønneland, Inês Barroso, Guy Fagherazzi, Nita G. Forouhi, Carlotta Sacerdote, Kim Overvad, Aurelio Barricarte, Nicholas J. Wareham, Sara Grioni, Tove Fall, Françoise Clavel-Chapelon, Olov Rolandsson, Heiner Boeing, Jacqueline M. Dekker, Mark Walker, Adam Barker, Vilmantas Giedraitis, Daphne L. van der A, Claudia Langenberg, Diana Gavrila, David B. Savage, Ele Ferrannini, Matthias B. Schulze, Hanieh Yaghootkar, Nadia Slimani, Paul W. Franks, Erik Ingelsson, Annemieke M.W. Spijkerman, Robert A. Scott, Ivonne Sluijs, Rosario Tumino, Stephen J. Sharp, Salvatore Panico, Robert K. Semple, Beverley Balkau, Leif Groop, Domenico Palli, Timothy M. Frayling, J. Ramón Quirós, Rudolf Kaaks

المساهمون: Scott, Ra, Fall, T, Pasko, D, Barker, A, Sharp, Sj, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Boeing, H, Clavel Chapelon, F, Crowe, Fl, Dekker, Jm, Fagherazzi, G, Ferrannini, E, Forouhi, Ng, Franks, Pw, Gavrila, D, Giedraitis, V, Grioni, S, Groop, Lc, Kaaks, R, Key, Tj, K?hn, T, Lotta, La, Nilsson, Pm, Overvad, K, Palli, D, Panico, Salvatore, Quir?s, Jr, Rolandsson, O, Roswall, N, Sacerdote, C, Sala, N, S?nchez, Mj, Schulze, Mb, Siddiq, A, Slimani, N, Sluijs, I, Spijkerman, Am, Tjonneland, A, Tumino, R, van der A., Dl, Yaghootkar, H, Mccarthy, Mi, Semple, Rk, Riboli, E, Walker, M, Ingelsson, E, Frayling, Tm, Savage, Db, Langenberg, C, Wareham, Nj, The RISC The study group InterAct, Consortium, Epidemiology and Data Science, EMGO - Lifestyle, overweight and diabetes

المصدر: Scott, R A, Fall, T, Pasko, D, Barker, A, Sharp, S J, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Boeing, H, Clavel-Chapelon, F, Crowe, F L, Dekker, J M, Fagherazzi, G, Ferrannini, E, Forouhi, N G, Franks, P W, Gavrila, D, Giedraitis, V, Grioni, S, Groop, L C, Kaaks, R, Key, T J, Kuhn, T, Lotta, L A, Nilsson, P M, Overvad, K, Palli, D, Panico, S, Quiros, J R, Rolandsson, O, Roswall, N, Sacerdote, C, Sala, N, Sanchez, MJ, Schulze, M B, Siddiq, A, Slimani, N, Sluijs, I, Spijkerman, A M W, Tjonneland, A, Tumino, R, van der A, D L, Yaghootkar, H, McCarthy, M I, Semple, R K, Riboli, E, Walker, M, Ingelsson, E, Frayling, T M, Savage, D B, Langenberg, C & Wareham, N J 2014, ' Common Genetic Variants Highlight the Role of Insulin Resistance and Body Fat Distribution in Type 2 Diabetes, Independent of Obesity ', Diabetes, vol. 63, no. 12, pp. 4378-4387 . https://doi.org/10.2337/db14-0319Test
Scott, R A, Fall, T, Pasko, D, Barker, A, Sharp, S J, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Boeing, H, Clavel-Chapelon, F, Crowe, F L, Dekker, J M, Fagherazzi, G, Ferraninini, E, Forouhi, N G, Franks, P W, Gavrila, D, Giedraitis, V, Grioni, S, Groop, L C, Kaaks, R, Key, T J, Kühn, T, Lotta, L, Nilsson, P M, Overvad, K, Palli, D, Panico, S, Quirós, J R, Rolandsson, O, Roswall, N, Sacerdote, C, Sala, N, Sánchez, M-J, Schulze, M B, Siddiq, A, Slimani, N, Sluijs, I, Spijkerman, A M, Tjonneland, A, Tumino, R, van der A, D L, Yaghootkar, H, McCarthy, M I, Semple, R K, Riboli, E, Walker, M, Ingelsson, E, Frayling, T M & The RISC study group 2014, ' Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity ', Diabetes, vol. 63, no. 12, pp. 4378-4387 . https://doi.org/10.2337/db14-0319Test
Scott, R A, Fall, T, Pasko, D, Barker, A, Sharp, S J, Arriola, L, Balkau, B, Barricarte, A, Barroso, I, Boeing, H, Clavel-Chapelon, F, Crowe, F L, Dekker, J M, Fagherazzi, G, Ferraninini, E, Forouhi, N G, Franks, P W, Gavrila, D, Giedraitis, V, Grioni, S, Groop, L C, Kaaks, R, Key, T J, Kühn, T, Lotta, L, Nilsson, P M, Overvad, K, Palli, D, Panico, S, Quirós, J R, Rolandsson, O, Roswall, N, Sacerdote, C, Sala, N, Sánchez, M-J, Schulze, M B, Siddiq, A, Slimani, N, Sluijs, I, Spijkerman, A M, Tjonneland, A, Tumino, R, van der A, D L, Yaghootkar, H, McCarthy, M I, Semple, R K, Riboli, E, Walker, M, Ingelsson, E, Frayling, T M & The RISC study group 2014, ' Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity ', Diabetes, vol. 63, no. 12, pp. 4378-87 . https://doi.org/10.2337/db14-0319Test
Diabetes, 63(12), 4378-4387. American Diabetes Association Inc.

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Type 2 diabetes, Overweight, Polymorphism, Single Nucleotide, Article, Body Mass Index, Cohort Studies, Insulin resistance, Diabetes mellitus, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Body Fat Distribution, Humans, Insulin, Genetic Predisposition to Disease, Obesity, Aged, 2. Zero hunger, Glucose tolerance test, medicine.diagnostic_test, business.industry, nutritional and metabolic diseases, Genetic Variation, Alanine Transaminase, gamma-Glutamyltransferase, Glucose clamp technique, Glucose Tolerance Test, Middle Aged, medicine.disease, Endocrinology, Diabetes Mellitus, Type 2, Body Composition, Glucose Clamp Technique, Female, medicine.symptom, Insulin Resistance, Waist Circumference, business

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https://doi.org/10.2337/db14-0319Test