يعرض 1 - 7 نتائج من 7 نتيجة بحث عن '"Wicker, Linda S"', وقت الاستعلام: 1.78s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

    المؤلفون: Yang, Jennie H. M., Cutler, Antony J., Ferreira, Ricardo C., Reading, James L., Cooper, Nicholas J., Wallace, Chris, Clarke, Pamela, Smyth, Deborah J., Boyce, Christopher S., Guo-Jian Gao, Todd, John A., Wicker, Linda S., Tree, Timothy I. M., Gao, Guo-Jian

    المصدر: Diabetes; Nov2015, Vol. 64 Issue 11, p3891-3902, 12p, 1 Diagram, 7 Graphs

    مصطلحات موضوعية: INTERLEUKIN-2, T cells, TYPE 1 diabetes, HOMEOSTASIS, GENETIC polymorphisms, IMMUNOTHERAPY, PHOSPHORYLATION, CELLULAR signal transduction, ESTERASES, RESEARCH funding, GENOTYPES, PHYSIOLOGY

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  2. 2
    دورية أكاديمية
    IL-2 and its high-affinity receptor: Genetic control of immunoregulation and autoimmunity

    المؤلفون: Wang, Jinguo1, Wicker, Linda S.2, Santamaria, Pere1 psantama@ucalgary.ca

    المصدر: Seminars in Immunology. Dec2009, Vol. 21 Issue 6, p363-371. 9p.

    مصطلحات موضوعية: *GENETIC regulation, *IMMUNOREGULATION, *AUTOIMMUNITY, *GENETICS of diabetes, *LYMPHOCYTES, *GENETIC polymorphisms


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  3. 3
    دورية أكاديمية
    Amino acid polymorphisms altering the glycosylation of IL-2 do not protect from type 1 diabetes in the NOD mouse.

    المؤلفون: Kamanaka, Masahito, Rainbow, Dan, Schuster-Gossler, Karin, Eynon, Elizabeth E., Chervonsky, Alexander V., Wicker, Linda S., Flavell, Richard A.

    المصدر: Proceedings of the National Academy of Sciences of the United States of America; 7/7/2009, Vol. 106 Issue 27, p11236-11240, 5p

    مصطلحات موضوعية: DIABETES, AMINO acids, GENETIC polymorphisms, GLYCOSYLATION, LABORATORY mice

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  4. 4
    دورية أكاديمية
    Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

    المؤلفون: Lowe, Christopher E., Cooper, Jason D., Brusko, Todd, Walker, Neil M., Smyth, Deborah J., Bailey, Rebecca, Bourget, Kirsi, Plagnol, Vincent, Field, Sarah, Atkinson, Mark, Clayton, David G., Wicker, Linda S., Todd, John A.

    المصدر: Nature Genetics; Sep2007, Vol. 39 Issue 9, p1074-1082, 9p, 1 Diagram, 4 Charts, 2 Graphs

    مصطلحات موضوعية: GENE mapping, GENETIC polymorphisms, GENOTYPE-environment interaction, DIABETES, CHROMOSOMES, INTERLEUKINS


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  5. 5
    دورية أكاديمية
    Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes.

    المؤلفون: Taniguchi, Hidenori, Lowe, Christopher E, Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Nutland, Sarah, Healy, Barry C, Lam, Alex C, Burren, Oliver, Walker, Neil M, Smink, Luc J, Wicker, Linda S, Todd, John A

    المصدر: BMC Genetics; 2006, Vol. 7, p22-9, 9p, 1 Color Photograph, 3 Charts

    مصطلحات موضوعية: DIABETES, AUTOIMMUNE diseases, PANCREATIC beta cells, MEMBRANE proteins, GENETIC polymorphisms

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  6. 6
    دورية أكاديمية
    Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.

    المؤلفون: Penha-Gonçalves, Carlos, Moule, Carolyn, Smink, Luc J., Howson, Joanna, Gregory, Simon, Rogers, Jane, Lyons, Paul A., Suttie, Joseph J., Lord, Christopher J., Peterson, Laurence B., Todd, John A., Wicker, Linda S., Penha-Gonçalves, Carlos

    المصدر: Diabetes; Jun2003, Vol. 52 Issue 6, p1551-1556, 6p, 1 Diagram, 1 Chart, 1 Graph

    مصطلحات موضوعية: GENETICS, DIABETES, AMINO acids, ANIMAL experimentation, ANTIGENS, COMPARATIVE studies, DISEASE susceptibility, DOCUMENTATION, GENE mapping, GENES, GENETIC polymorphisms, TYPE 1 diabetes, RESEARCH methodology, MEDICAL cooperation, MICE, NUCLEOTIDES, RESEARCH, GENETIC markers, EVALUATION research, MEMBRANE glycoproteins

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  7. 7
    دورية أكاديمية
    Type 1 Diabetes-Associated IL2RA Variation Lowers IL-2 Signaling and Contributes to Diminished CD4+CD25+ Regulatory T Cell Function.

    المؤلفون: Garg, Garima1,2, Tyler, Jennifer R.1, Yang, Jennie H. M.1, Cutler, Antony J.3, Downes, Kate3, Pekalski, Marcin3, Bell, Gwynneth L.3, Nutland, Sarah3, Peakman, Mark1,2, Todd, John A.3, Wicker, Linda S.3, Tree, Timothy I. M.1,2 timothy.tree@kcl.ac.uk

    المصدر: Journal of Immunology. 5/1/2012, Vol. 188 Issue 9, p4644-4653. 10p.

    مصطلحات موضوعية: *INTERLEUKIN-2, *T cells, *TYPE 1 diabetes, *AUTOIMMUNE diseases, *GENETIC polymorphisms, *PHOSPHORYLATION


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