المؤلفون: Ming-Huei Chen, Lisa R. Yanek, Joshua D. Backman, John D. Eicher, Jennifer E. Huffman, Yoav Ben-Shlomo, Andrew D. Beswick, Laura M. Yerges-Armstrong, Alan R. Shuldiner, Jeffrey R. O’Connell, Rasika A. Mathias, Diane M. Becker, Lewis C. Becker, Joshua P. Lewis, Andrew D. Johnson, Nauder Faraday

المصدر: Platelets, Vol 30, Iss 2, Pp 164-173 (2019)

مصطلحات موضوعية: platelets, platelet aggregation, snp, genetic association, exome, platelet reactivity, Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/0953-7104Test; https://doaj.org/toc/1369-1635Test

الوصول الحر: https://doaj.org/article/5aa226b92c0744349f37efaa641d1094Test

المؤلفون: Nicholas L. Smith, James A. Perry, Cecelia A. Laurie, Nancy J. Cox, Gonçalo R. Abecasis, Jerome I. Rotter, Laura Almasy, Zhe Wang, Michelle Daya, Yun Li, Eric Jorgenson, Adolfo Correa, Jai G. Broome, Nancy Min, Lisa R. Yanek, Alanna C. Morrison, Lynette Ekunwe, Debby Ngo, Victor E. Ortega, Klaudia Walter, John Blangero, Laura M. Raffield, Corey Cox, Terri H. Beaty, Deborah A. Meyers, Hua Tang, Marsha M. Wheeler, Kari E. North, Xue Zhong, Yann Ilboudo, Andrew D. Johnson, Caitlin P. McHugh, Jeffrey R. O'Connell, Ming-Huei Chen, Russell P. Tracy, Ramachandran S. Vasan, Nathan Pankratz, Joshua P. Lewis, Dawn L. DeMeo, Linda M. Polfus, Leslie A. Lange, Nancy L. Heard-Costa, Robert C. Kaplan, Meher Preethi Boorgula, Robert E. Gerszten, Albert V. Smith, Paul L. Auer, Sameer Chavan, Jennifer A. Brody, Charles Kooperberg, Michael Preuss, David C. Glahn, Rasika A. Mathias, Paul S. de Vries, Jonathon Rosen, Anna V. Mikhaylova, Joe Zein, Eric Boerwinkle, Nathalie Chami, Kathleen C. Barnes, Joanne E. Curran, Edwin K. Silverman, Matthew P. Conomos, Stephen S. Rich, Nicole Soranzo, Heather M. Highland, Michael H. Cho, Donald M. Lloyd-Jones, Myriam Fornage, Guillaume Lettre, Tyne W Miller-Fleming, Kathleen A. Ryan, Thomas W. Blackwell, Bruce M. Psaty, Lewis C. Becker, Nauder Faraday, Hélène Choquet, Alexander P. Reiner, Adam S. Butterworth, Kousik Kundu, Deepti Jain, Timothy A. Thornton, Brian D. Hobbs, Braxton D. Mitchell, Jee-Young Moon, Lifang Hou, Ani Manichaikul, Praveen Surendran, Suraj S. Nongmaithem, Quan Sun, Bingshan Li, Deborah A. Nickerson, Ruth J. F. Loos

المصدر: Am J Hum Genet

مصطلحات موضوعية: Proteome, Quantitative Trait Loci, Genome-wide association study, Biology, Polymorphism, Single Nucleotide, Article, Dermatitis, Atopic, Pulmonary Disease, Chronic Obstructive, Leukocytes, Genetics, medicine, Humans, Genetic Predisposition to Disease, Gene, Genetics (clinical), X chromosome, Genetic association, Whole genome sequencing, Autosome, Whole Genome Sequencing, Genome, Human, Monocyte, Prognosis, Asthma, United Kingdom, United States, Phenotype, medicine.anatomical_structure, National Heart, Lung, and Blood Institute (U.S.), Biomarkers, Imputation (genetics), Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cbe1c35e5654539a7823886e9881b7Test
https://doi.org/10.1016/j.ajhg.2021.08.007Test

المؤلفون: Laura M. Raffield, Michael Preuss, Danyu Lin, Charles Kooperberg, Alexander P. Reiner, Antoine R Baldassari, Colleen M. Sitlani, Christy L. Avery, Laura M. Huckins, Ruth J. F. Loos, Katherine K. Nishimura, Lihong Qi, Yao Hu, Abdou Mousas, Mariaelisa Graff, Bharat Thyagarajan, Yun Li, Ran Tao, Guillaume Lettre, Quan Sun, Heather M. Highland, Jeffrey Haessler, Myriam Fornage, Kari E. North, Ulrike Peters, Chani J. Hodonsky, Weihong Tang, Zhe Wang, Paul L. Auer, Steve Buyske, Ming-Huei Chen, Stephanie A. Bien, Lucia A. Hindorff, Genevieve L. Wojcik

المصدر: BMC Genomics, Vol 22, Iss 1, Pp 1-11 (2021)
BMC Genomics

مصطلحات موضوعية: Platelets, medicine.medical_specialty, Population, Ethnic group, Genome-wide association study, Genomics, Multi-ethnic, Biology, QH426-470, Polymorphism, Single Nucleotide, 03 medical and health sciences, White blood cell, Epidemiology, medicine, Leukocytes, Genetics, Humans, GWAS, Genetic Predisposition to Disease, education, Gene, 030304 developmental biology, Genetic association, 0303 health sciences, education.field_of_study, 030305 genetics & heredity, Correction, medicine.anatomical_structure, Phenotype, White blood cells, TP248.13-248.65, Research Article, Genome-Wide Association Study, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08259d0a7ba341a3d0b6a4a39fbba78dTest
https://doaj.org/article/492ab9ab7f354c8e890b3502d9d97085Test

المؤلفون: Adolfo Correa, Jai G. Broome, Chunyan Ren, Kari E. North, Nancy L. Heard-Costa, Yao Yao, Brian D. Hobbs, Mary Cushman, Leslie A. Lange, Daniel E. Bauer, Xiuwen Zheng, Braxton D. Mitchell, Yun Li, Quan Sun, Sébastian Méric de Bellefon, Terri H. Beaty, Paul S. de Vries, Ruth J. F. Loos, Adrienne M. Stilp, Albert V. Smith, Paul L. Auer, Deepti Jain, Lifang Hou, Robert C. Kaplan, Jee-Young Moon, Michael Preuss, Stephen S. Rich, Guillaume Lettre, Nicole Soranzo, Eric Boerwinkle, Kousik Kundu, Laura Almasy, Marsha M. Wheeler, Thomas W. Blackwell, Nancy Min, Nicholas L. Smith, Bruce M. Psaty, Lisa R. Yanek, Joanne E. Curran, Stacey Gabriel, Kathleen A. Ryan, Alanna C. Morrison, Lynette Ekunwe, Caitlin P. McHugh, Laura M. Raffield, Adam S. Butterworth, Deborah A. Nickerson, Ravindranath Duggirala, Gonçalo R. Abecasis, John Lane, Hélène Choquet, Andrew D. Johnson, Nauder Faraday, Russell T. Walton, Praveen Surendran, Jennifer A. Brody, Yao Hu, Alexander P. Reiner, Jerome I. Rotter, Donald M. Lloyd-Jones, Cathy C. Laurie, Zhe Wang, Hua Tang, Charles Kooperberg, Eric Jorgenson, Jeffrey R. O'Connell, Shuquan Rao, Nathalie Chami, Rasika A. Mathias, Matthew P. Conomos, Myriam Fornage, Ramachandran S. Vasan, Nathan Pankratz, Joshua P. Lewis, Lewis C. Becker, Benjamin P. Kleinstiver, Cecelia A. Laurie, Ming-Huei Chen, John Blangero

المصدر: Am J Hum Genet

مصطلحات موضوعية: Adult, Male, Quality Control, 0301 basic medicine, Erythrocytes, Population, Datasets as Topic, Genome-wide association study, Biology, Quantitative trait locus, Article, 03 medical and health sciences, 0302 clinical medicine, Genetics, Humans, Indel, education, Gene, Genetics (clinical), Aged, Genetic association, Gene Editing, Whole genome sequencing, education.field_of_study, Genetic Variation, Reproducibility of Results, Correction, Middle Aged, United States, Genetic architecture, HEK293 Cells, Phenotype, 030104 developmental biology, 030220 oncology & carcinogenesis, Female, National Heart, Lung, and Blood Institute (U.S.), Chromosomes, Human, Pair 16, Genome-Wide Association Study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b87edb710dac1b94b0361a1b7107d06Test
https://doi.org/10.1016/j.ajhg.2021.04.003Test

المؤلفون: Melissa V. Chan, Andrew D. Johnson, Ming-Huei Chen, Florian Thibord

مصطلحات موضوعية: Genetics, Apolipoprotein E, Coronavirus disease 2019 (COVID-19), ABO blood group system, Locus (genetics), Genome-wide association study, Biology, Biobank, Phenotype, Genetic association

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::2e82b30d772e943e5cb2eb42decf61a4Test
https://doi.org/10.1101/2021.06.08.21258507Test

المؤلفون: Ming-Huei Chen, Achilleas N. Pitsillides, Qiong Yang

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

مصطلحات موضوعية: Multifactorial Inheritance, Genotype, Population genetics, Science, Biology, Logistic regression, Polymorphism, Single Nucleotide, Article, Framingham Heart Study, Gene Frequency, Statistics, Humans, Computer Simulation, Longitudinal Studies, Precision Medicine, Alleles, Genetic association, Whole genome sequencing, Multidisciplinary, Models, Genetic, Genome, Human, Rare variants, Minor allele frequency, Logistic Models, Likelihood-ratio test, Medicine, Software, Genome-Wide Association Study, Type I and type II errors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f515be3db320845d0b554be667af3e63Test
https://doi.org/10.1038/s41598-021-82547-zTest

المؤلفون: Saonli Basu, Lu-Chen Weng, Weihua Guan, Mary Cushman, Lyn M. Steffen, James S. Pankow, Aaron R. Folsom, Weihong Tang, Ming-Huei Chen, Nathan Pankratz

المصدر: Thrombosis Research. 168:53-59

مصطلحات موضوعية: Male, 0301 basic medicine, Locus (genetics), Single-nucleotide polymorphism, Genome-wide association study, Biology, Fibrinogen, Hemostatics, Article, 03 medical and health sciences, Fatty Acids, Omega-3, medicine, Humans, Genetic association, chemistry.chemical_classification, Genetics, Genetic Variation, Fatty acid, Genetic Pleiotropy, Hematology, Middle Aged, 030104 developmental biology, chemistry, Fatty Acids, Unsaturated, Female, Protein C, Polyunsaturated fatty acid, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c76d838735e51c979cfa7220235bb02Test
https://doi.org/10.1016/j.thromres.2018.05.032Test

المؤلفون: Paul L. Auer, Laura Almasy, Jerome I. Rotter, Nancy Min, Lisa R. Yanek, Shuquan Rao, Hua Tang, Zhe Wang, Stacey Gabriel, Jee-Young Moon, Nancy L. Heard-Costa, Adam S. Butterworth, Ravindranath Duggirala, Cathy C. Laurie, Hélène Choquet, Ruth J. F. Loos, Alanna C. Morrison, Eric Jorgenson, Charles Kooperberg, Rasika A. Mathias, Laura M. Raffield, Nicholas L. Smith, Andrew D. Johnson, Matthew P. Conomos, Lynette Ekunwe, Donald M. Lloyd-Jones, Gonçalo R. Abecasis, Robert C. Kaplan, Myriam Fornage, Daniel E. Bauer, Nathalie Chami, Lewis C. Becker, Leslie A. Lange, Ming-Huei Chen, Brian D. Hobbs, Paul S. de Vries, Terri H. Beaty, Cecelia A. Laurie, Eric Boerwinkle, Michael Preuss, Adrienne M. Stilp, Jeffrey R. O'Connell, Kousik Kundu, Joanne E. Curran, Mary Cushman, Kari E. North, Xiuwen Zheng, John Blangero, Sébastian Méric de Bellefon, Ramachandran S. Vasan, Nathan Pankratz, Praveen Surendran, Joshua P. Lewis, Kathleen A. Ryan, Jennifer A. Brody, Deepti Jain, Braxton D. Mitchell, Marsha M. Wheeler, Lifang Hou, Deborah A. Nickerson, Guillaume Lettre, Alexander P. Reiner, Albert V. Smith, Stephen S. Rich, Nicole Soranzo, Adolfo Correa, Jai G. Broome, Nauder Faraday, Thomas W. Blackwell, Bruce M. Psaty, Quan Sun, Yun Li, Caitlin P. McHugh, Yao Hu, John Lane

مصطلحات موضوعية: Genetics, Whole genome sequencing, education.field_of_study, Population, Genome-wide association study, Quantitative trait locus, Biology, Genetic architecture, symbols.namesake, Mendelian inheritance, symbols, Indel, education, Genetic association

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::740854b9674d9c60813159f3acb4cc59Test
https://doi.org/10.1101/2020.12.09.20246736Test

المؤلفون: Xiuqing Guo, Karen M. Mutalik, Nora Franceschini, Carla Wilson, Elizabeth C. Oelsner, Kerri L. Wiggins, Ming-Huei Chen, Cashell E. Jaquish, Charles Kooperberg, Nicola L. Hawley, Adrienne M. Stilp, Kathleen C. Barnes, Chancellor Hohensee, Pradeep Natarajan, Alyna T. Khan, Jingmin Liu, Gina M. Peloso, Fei Fei Wang, Adolfo Correa, Laura M. Raffield, Mariza de Andrade, Jai G. Broome, Patricia A. Peyser, Andrew D. Johnson, Brian E. Cade, Rebecca D. Jackson, Lucia Juarez, Braxton D. Mitchell, Dongquan Chen, Nancy L. Heard-Costa, Shannon Kelly, Kent D. Taylor, Susan R. Heckbert, Stephen T. McGarvey, Tanika N. Kelly, Sharon L.R. Kardia, Jerome I. Rotter, Weiniu Gan, Paul S. de Vries, Lawrence F. Bielak, May E. Montasser, Erin J Buth, Quenna Wong, Jennifer A. Smith, Patrick T. Ellinor, Alanna C. Morrison, Ramachandran S. Vasan, Nathan Pankratz, Wan-Ling Hsu, Cecelia A. Laurie, Jan Graffelman, Daniel E. Weeks, Scott T. Weiss, Seyed Mehdi Nouraie, Cathy C. Laurie, Joshua C. Bis, Kari E. North, William Craig Johnson, L. Adrienne Cupples, Catherine M. D’Augustine, Donna K. Arnett, Stephen S. Rich, Bruce M. Psaty, Leslie S. Emery, Lisa R. Yanek, Jiwon Lee, Stella Aslibekyan, Myriam Fornage, Rasika A. Mathias, Megan L. Grove, Santhi K. Ganesh, Alexander P. Reiner

مصطلحات موضوعية: Data sharing, Documentation, Data collection, Computer science, Controlled vocabulary, Harmonization, Precision medicine, Omics, Data science, Phenotype, Domain (software engineering), Genetic association

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d439f674af01e2aa4064e9648cc28f87Test
https://doi.org/10.1101/2020.06.18.146423Test

المؤلفون: Robert Kraaij, Teresa Nutile, Peter Vollenweider, Cassianne Robinson-Cohen, Caroline S. Fox, André G. Uitterlinden, Sanaz Sedaghat, Cornelia M. van Duijn, Alanna C. Morrison, Meng Li, Bing Yu, Sahar Ghasemi, Zoltán Kutalik, Eric Boerwinkle, Alexanda Teumer, Jeroen van Rooij, Qiong Yang, Audrey Y. Chu, Jennifer E. Huffman, Bruce M. Psaty, Jun Liu, Najaf Amin, Jennifer A. Brody, Adrienne Tin, Rossella Sorice, Ming-Huei Chen, Marina Ciullo, Anna Köttgen, Yong Li, Ayse Demirkan, Owen M. Woodward, Melody Swen, Abbas Dehghan, Aurélien Macé, Barbara McKnight

المساهمون: Epidemiology, Internal Medicine

المصدر: Nature Communications
Nature communications 9 (2018). doi:10.1038/s41467-018-06620-4
info:cnr-pdr/source/autori:Tin A.; Li Y.; Brody J.A.; Nutile T.; Chu A.Y.; Huffman J.E.; Yang Q.; Chen M.-H.; Robinson-Cohen C.; Mace A.; Liu J.; Demirkan A.; Sorice R.; Sedaghat S.; Swen M.; Yu B.; Ghasemi S.; Teumer A.; Vollenweider P.; Ciullo M.; Li M.; Uitterlinden A.G.; Kraaij R.; Amin N.; van Rooij J.; Kutalik Z.; Dehghan A.; McKnight B.; van Duijn C.M.; Morrison A.; Psaty B.M.; Boerwinkle E.; Fox C.S.; Woodward O.M.; Kottgen A./titolo:Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels/doi:10.1038%2Fs41467-018-06620-4/rivista:Nature communications/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, 9:4228. Nature Publishing Group
Nature communications, vol. 9, no. 1, pp. 4228

مصطلحات موضوعية: 0301 basic medicine, Organic Cation Transport Proteins, Science, Glucose Transport Proteins, Facilitative, General Physics and Astronomy, Organic Anion Transporters, Genome-wide association study, Disease, Bioinformatics, Kidney Function Tests, General Biochemistry, Genetics and Molecular Biology, Article, Protein Structure, Secondary, 03 medical and health sciences, chemistry.chemical_compound, Exome/genetics, Genetic Predisposition to Disease, Glucose Transport Proteins, Facilitative/chemistry, Glucose Transport Proteins, Facilitative/genetics, Glucose Transport Proteins, Facilitative/metabolism, Humans, Meta-Analysis as Topic, Organic Anion Transporters/chemistry, Organic Anion Transporters/genetics, Organic Anion Transporters/metabolism, Organic Cation Transport Proteins/chemistry, Organic Cation Transport Proteins/genetics, Organic Cation Transport Proteins/metabolism, Uric Acid/blood, MD Multidisciplinary, medicine, Exome, lcsh:Science, Exome sequencing, Genetic association, Multidisciplinary, biology, business.industry, Lesinurad, serum urate levels, General Chemistry, medicine.disease, 3. Good health, Gout, Uric Acid, 030104 developmental biology, chemistry, biology.protein, SLC22A12, lcsh:Q, business, SLC2A9

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09617704df3edc2b2becb350d2b1af49Test
https://doi.org/10.1038/s41467-018-06620-4Test