المؤلفون: Zhengxing Zhi, Gang Xing, Maosheng Cheng, Bin Lin, Ce Yi, Peiyuan Dou

المصدر: Expert Opinion on Therapeutic Patents. 31:239-246

مصطلحات موضوعية: Muscarinic Antagonists, 01 natural sciences, β2 adrenergic receptor, Patents as Topic, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, 0302 clinical medicine, Drug Development, Smooth muscle, Drug Discovery, Animals, Humans, Medicine, Receptor, Adrenergic beta-2 Receptor Agonists, G protein-coupled receptor, Pharmacology, business.industry, food and beverages, General Medicine, Asthma, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030220 oncology & carcinogenesis, business, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf55e3dd52661976ac0d600d56029e8Test
https://doi.org/10.1080/13543776.2021.1865312Test

المؤلفون: Masato Mashimo, Yoshika Fukuda, Marina Fujii, Natsumi Sakagawa, Rika Imanaka, Takeshi Fujii

المصدر: Biologicalpharmaceutical bulletin. 43(12)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Pharmaceutical Science, Immunoglobulins, Muscarinic Antagonists, Immunoglobulin G, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Muscarinic acetylcholine receptor, medicine, Humans, Receptor, B cell, Acetylcholine receptor, Pharmacology, B-Lymphocytes, biology, Chemistry, Interleukin-6, Interleukin, General Medicine, Molecular biology, Receptors, Muscarinic, 030104 developmental biology, medicine.anatomical_structure, Cytokine, Immunoglobulin class switching, 030220 oncology & carcinogenesis, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4fd26e85e853bdf3f3c2738f0e8771Test
https://pubmed.ncbi.nlm.nih.gov/33268714Test

المؤلفون: Monika Kustermann, Svenja Laue, Yinghong Cui, Douglas G. Tilley, Laurel A. Grisanti, Melanie Rothe, Michael Kauk, Carsten Hoffmann, Melanie Philipp, WH Zimmermann, Teresa Casar Tena, Allessandra Moretti, Farah Raad, Michael Kühl, Martina S. Burczyk, Sabrina Matysik, Martin D. Burkhalter, Cornelia Donow, Jürgen Wess

المصدر: JCI Insight

مصطلحات موضوعية: 0301 basic medicine, Embryo, Nonmammalian, Tolterodine Tartrate, Organogenesis, Muscarinic Antagonists, Mice, Xenopus laevis, 03 medical and health sciences, 0302 clinical medicine, Heart Conduction System, Muscarinic acetylcholine receptor, Heart rate, medicine, Animals, Humans, Myocytes, Cardiac, Receptor, Zebrafish, Mice, Knockout, Receptor, Muscarinic M3, Sinoatrial node, business.industry, fungi, Muscarinic acetylcholine receptor M3, Arrhythmias, Cardiac, General Medicine, Embryo, Mammalian, medicine.disease, 3. Good health, Disease Models, Animal, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Heart failure, Atrioventricular canal, Electrical conduction system of the heart, business, Neuroscience, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d95a3d11c2efe67a92a1fc8c1ec423aTest
https://doi.org/10.1172/jci.insight.121971Test

المؤلفون: Michael Decker, Ulrike Holzgrabe

المصدر: Expert Opinion on Therapeutic Patents. 27:121-125

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Allosteric regulation, Muscarinic Antagonists, Muscarinic Agonists, Ligands, Patents as Topic, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Functional selectivity, Humans, Receptor, Benzoic acid, Pharmacology, Chemistry, General Medicine, Neuromuscular Blocking Agents, Receptors, Muscarinic, 030104 developmental biology, Drug Design, Selectivity, Allosteric Site, Acetylcholine, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3d3f30b52505cc487ddb5ce3d946a4Test
https://doi.org/10.1080/13543776.2017.1272577Test

المؤلفون: Mithat Gonen, Young Rock Chung, Omar Abdel-Wahab, Lillian Bitner, Gaurang Trivedi, Justin Taylor, Jürgen Wess, Daichi Inoue, Lingbo Zhang, Cynthia Chen

المصدر: Sci Transl Med

مصطلحات موضوعية: Erythrocytes, Muscarinic Antagonists, Biology, CREB, Article, Mice, Erythroid Cells, hemic and lymphatic diseases, Muscarinic acetylcholine receptor, Animals, Humans, Erythropoiesis, Progenitor cell, Cell Self Renewal, Receptor, Transcription factor, Erythroid Precursor Cells, Acetylcholine receptor, Stem Cells, Anemia, General Medicine, Receptors, Muscarinic, Cell biology, Mice, Inbred C57BL, Haematopoiesis, Gene Expression Regulation, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f59361c573e1cabd6a557f2e13f30dTest
https://pubmed.ncbi.nlm.nih.gov/31554738Test

المؤلفون: Naoto Hoshi, Anastasia Kosenko, Seungwoo Kang, Derek L. Greene, Hee Yeon Kay

المصدر: The Journal of clinical investigation, vol 125, iss 10

مصطلحات موضوعية: Male, medicine.medical_treatment, A Kinase Anchor Proteins, Action Potentials, Neurodegenerative, Phenylenediamines, Pharmacology, Inbred C57BL, Medical and Health Sciences, Hippocampus, Mice, chemistry.chemical_compound, Epilepsy, Muscarinic acetylcholine receptor, M current, Drug Interactions, Phosphorylation, Cells, Cultured, Anthracenes, Neurons, Valproic Acid, Cultured, Kainic Acid, Retigabine, General Medicine, 5.1 Pharmaceuticals, Neurological, Anticonvulsants, Female, lipids (amino acids, peptides, and proteins), Development of treatments and therapeutic interventions, medicine.symptom, Receptor, Research Article, Signal Transduction, medicine.drug, Kainic acid, Cells, Lipoylation, Recombinant Fusion Proteins, Immunology, Muscarinic Antagonists, Superior Cervical Ganglion, Muscarinic Agonists, Seizures, Potassium Channel Blockers, medicine, Animals, Humans, KCNQ2 Potassium Channel, Protein Processing, Receptor, Muscarinic M1, Post-Translational, Neurosciences, medicine.disease, Brain Disorders, Rats, Mice, Inbred C57BL, Anticonvulsant, Mechanism of action, chemistry, Muscarinic M1, Carbamates, Protein Processing, Post-Translational

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e342ece078cc114a100a3f031b5abfTest
https://doi.org/10.1172/jci79727Test

المؤلفون: Osamu Nishiyama, Hiroaki Kume, Takaaki Isoya, Yukihiro Noda, Yuji Tohda, Yuji Higashimoto

المصدر: International Journal of Molecular Sciences
Volume 19
Issue 7
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1999 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Intrinsic activity, β2-adrenoceptor agonists, Pharmacology, lcsh:Chemistry, Potassium Channels, Calcium-Activated, large-conductance Ca2+-activated K+ channels, Muscarinic acetylcholine receptor, Receptor, lcsh:QH301-705.5, Spectroscopy, Chemistry, Muscarinic acetylcholine receptor M2, General Medicine, Computer Science Applications, Trachea, Atropine, synergistic effects, L-type voltage-dependent Ca2+ channels, medicine.drug, G protein, Procaterol, Allosteric regulation, Guinea Pigs, Muscarinic Antagonists, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Allosteric Regulation, medicine, COPD, Animals, Physical and Theoretical Chemistry, Molecular Biology, muscarinic receptor antagonists, Adrenergic beta-2 Receptor Agonists, Receptor, Muscarinic M2, Organic Chemistry, Muscle, Smooth, asthma, respiratory tract diseases, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, Receptors, Adrenergic, beta-2

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d31c33c2a52479bb7a0b24088ba389Test
http://europepmc.org/articles/PMC6073859Test

المؤلفون: Mahmoud Saifeddine, Morley D. Hollenberg, Koichiro Mihara, William K. Stell, Brittany J. Carr, Rithwik Ramachandran, Neil M. Nathanson

المصدر: Physiology and Pharmacology Publications

مصطلحات موضوعية: Off-target, 0301 basic medicine, Atropine, Muscarinic antagonist, Muscarinic Antagonists, Pharmacology, Cholinergic Agonists, Ligands, Transfection, Dicyclomine, Clonidine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Receptors, Adrenergic, alpha-2, CRISPR-Associated Protein 9, Muscarinic acetylcholine receptor, medicine, Adrenergic alpha-2 Receptor Agonists, Myopia, Animals, Humans, Receptor, Receptor, Muscarinic M3, Receptor, Muscarinic M4, Nonspecific binding, Antagonist, General Medicine, Pirenzepine, Receptors, Muscarinic, Form-deprivation myopia, 030104 developmental biology, HEK293 Cells, chemistry, Alpha2a-adrenoceptor, Himbacine, Gene Knockdown Techniques, 030221 ophthalmology & optometry, Carbachol, Chickens, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c596f5c5f823bc2790d2c265817a823Test
https://pubmed.ncbi.nlm.nih.gov/29860464Test

المؤلفون: Luigino Calzetta, Mario Cazzola, Josuel Ora, Paola Rogliani, Maria Gabriella Matera

المساهمون: Rogliani, Paola, Ora, Josuel, Matera, Maria Gabriella, Cazzola, Mario, Calzetta, Luigino

مصطلحات موضوعية: LABA/LAMA FDC, Settore MED/10 - Malattie dell'Apparato Respiratorio, Bioinformatics, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Cardiovascular Disease, Drug Combination, Muscarinic acetylcholine receptor, Delayed-Action Preparation, Pharmacology (medical), 030212 general & internal medicine, Receptor, media_common, COPD, biology, Muscarinic acetylcholine receptor M2, General Medicine, Lama, Bronchodilator Agents, Muscarinic Antagonist, Drug Combinations, Cardiovascular Diseases, Drug, hormones, hormone substitutes, and hormone antagonists, Human, Adrenergic beta-2 Receptor Agonist, Chronic Obstructive, media_common.quotation_subject, LABA/LAMA FDCs, cardiovascular safety, Adrenergic beta-2 Receptor Agonists, Delayed-Action Preparations, Dose-Response Relationship, Drug, Humans, Muscarinic Antagonists, Dose-Response Relationship, Pulmonary Disease, 03 medical and health sciences, medicine, Adverse effect, Bronchodilator Agent, business.industry, medicine.disease, biology.organism_classification, Dual bronchodilation, 030228 respiratory system, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aff21ada85ba37c98962c3b639e0c4aTest
http://hdl.handle.net/2108/209474Test

المؤلفون: Misha F. Vrolijk, Ming Zhang, Guido R.M.M. Haenen

المساهمون: RS: NUTRIM - R3 - Respiratory & Age-related Health, Promovendi NTM, Farmacologie en Toxicologie, RS: CARIM - R2.03 - ECM + Wnt signaling

المصدر: International Journal of Molecular Sciences, Vol 19, Iss 1, p 18 (2017)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 1; Pages: 18
International journal of molecular sciences, 19(1):18. Multidisciplinary Digital Publishing Institute (MDPI)

مصطلحات موضوعية: 0301 basic medicine, Atropine, Male, anticholinergic accumulation, BLOOD, Traditional Chinese medicine, Pharmacology, Rats, Inbred WKY, lcsh:Chemistry, 0302 clinical medicine, EQUATION, Traditional Chinese Medicine, Receptors, Cholinergic, Medicine, Chinese Traditional, Receptor, lcsh:QH301-705.5, Spectroscopy, POPULATION, education.field_of_study, OUTCOMES, Chemistry, General Medicine, Risperidone, Computer Science Applications, RECEPTORS, RISK SCALES, Cimetidine, medicine.drug, medicine.drug_class, Population, Muscarinic Antagonists, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, ANTIOXIDANT CAPACITY, Theophylline, medicine, Anticholinergic, Journal Article, Total Atropine Equivalents, DRUGS, Animals, Humans, OLDER-PEOPLE, Physical and Theoretical Chemistry, education, Molecular Biology, Acetylcholine receptor, Ephedra sinica, Organic Chemistry, Pirenzepine, Rats, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, ASTHMA, 030217 neurology & neurosurgery, Drugs, Chinese Herbal

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9cdddef36c96a5d2d0d4b3b2997ac6Test
https://www.mdpi.com/1422-0067/19/1/18Test