نتائج البحث - "Lipoxygenase"

1

Natural Inhibitors against Potential Targets of Cyclooxygenase, Lipoxygenase and Leukotrienes

المؤلفون: Sisir Nandi, Sudatta Dey, Rishita Dey, Asmita Samadder, Anil Saxena

المصدر: Combinatorial Chemistry & High Throughput Screening. 25:2341-2357

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fbd5d995ba1b23b58e403774b6fef7Test
https://doi.org/10.2174/1386207325666210917111847Test

2

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition

المؤلفون: Mosaad S. Mohamed, Shahenda Mahgoub, Hend Medhat El-Shanbaky, Rania H. Abd El-Hameed, Sahar A. Ali

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 977-986 (2021)

مصطلحات موضوعية: Chemokine, medicine.drug_class, Inflammation, RM1-950, 01 natural sciences, Anti-inflammatory, Lipoxygenase, Structure-Activity Relationship, 4-Butyrolactone, Heterocyclic Compounds, Drug Discovery, medicine, Humans, 15-LOX inhibitors, Lipoxygenase Inhibitors, Pyridazinone, anti-inflammatory, Pharmacology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Tumor Necrosis Factor-alpha, TNF-α inhibitor, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Cyclooxygenase 2, biology.protein, Tumor necrosis factor alpha, selective COX-2 inhibitor, Cyclooxygenase, Therapeutics. Pharmacology, medicine.symptom, Research Article, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19667daf6d13bb3c9f348e6d97dfab69Test
http://europepmc.org/articles/PMC8118430Test

3

Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR

المؤلفون: Minakshi A. Meshram, Venkata Rao Kaki, Priyanka N. Makhal, Utkarsha O. Bhise

المصدر: European journal of medicinal chemistry. 225

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec66a875b168f9d4ad2cf49b8353df6Test
https://pubmed.ncbi.nlm.nih.gov/34479036Test

4

Anti-inflammatory and anti-virus potential of poxytrins, especially protectin DX

المؤلفون: Michel Lagarde, Nathalie Bernoud-Hubac, Michel Guichardant

المساهمون: Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CCSD, Accord Elsevier

المصدر: Biochimie
Biochimie, 2020, 179, pp.281-284. ⟨10.1016/j.biochi.2020.09.008⟩

مصطلحات موضوعية: 0301 basic medicine, Docosahexaenoic Acids, medicine.drug_class, [SDV]Life Sciences [q-bio], Anti-Inflammatory Agents, Inflammation, Review, Virus Replication, Antiviral Agents, Biochemistry, Anti-inflammatory, 03 medical and health sciences, Lipoxygenase, medicine, Animals, Humans, chemistry.chemical_classification, Reactive oxygen species, 030102 biochemistry & molecular biology, biology, Chemistry, Glutathione peroxidase, Brain, General Medicine, 3. Good health, [SDV] Life Sciences [q-bio], 030104 developmental biology, Prostaglandin-Endoperoxide Synthases, Docosahexaenoic acid, Fatty Acids, Unsaturated, biology.protein, Cyclooxygenase, medicine.symptom, Reactive Oxygen Species, Polyunsaturated fatty acid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cfe088263c9c22b38120640d127912Test
https://doi.org/10.1016/j.biochi.2020.09.008Test

5

The Protective Roles of Butein on Indomethacin Induced Gastric Ulcer in Mice

المؤلفون: Rustem Anil Ugan, Harun Un

المساهمون: Belirlenecek

المصدر: Eurasian Journal of Medicine, Vol 52, Iss 3, Pp 265-270 (2020)
Eurasian J Med

مصطلحات موضوعية: 0301 basic medicine, mice, Extract, Lipoxygenase, Generation, Pharmacology, Butein, medicine.disease_cause, Superoxide dismutase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, indomethacin, medicine, Inhibition, Flavonoids, ulcer, lcsh:R5-920, biology, Rhus-Verniciflua Stokes, business.industry, Stomach, Induced Expression, Antioxidant Activity, General Medicine, Glutathione, Malondialdehyde, Nitric-Oxide, Famotidine, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, biology.protein, Original Article, Quercetin, Gastritis, medicine.symptom, business, lcsh:Medicine (General), Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0260ae15552b67c92eff2b96d64de3Test
https://eajm.org/en/the-protective-roles-of-butein-on-indomethacin-induced-gastric-ulcer-in-mice-133299Test

6

Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation

المساهمون: Cheung, Sun-Yee, Werner, Marku, Esposito, Lucia, Troisi, Fabiana, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Gerstmeier, Jana, Koeberle, Andrea, Bilancia, Rossella, Rizza, Roberta, Rossi, Antonietta, Roviezzo, Fiorentina, Temml, Veronika, Schuster, Daniela, Stuppner, Hermann, Schubert-Zsilavecz, Manfred, Werz, Oliver, Hanke, Thoma, Pace, Simona

المصدر: European Journal of Medicinal Chemistry. 156:815-830

مصطلحات موضوعية: Male, 0301 basic medicine, Macrophage, Prostaglandin, Inflammation, Lipoxygenase Inhibitor, Proximity ligation assay, Pharmacology, Sulfonamide, Prostaglandin-E Synthase, Mice, 03 medical and health sciences, chemistry.chemical_compound, HEK293 Cell, Biosynthesis, Drug Discovery, medicine, Microsomal prostaglandin E2 synthase-1, Prostaglandin E2, Cells, Cultured, 5-Lipoxygenase, Arachidonate 5-Lipoxygenase, biology, Animal, Drug Discovery3003 Pharmaceutical Science, Specialized pro-resolving mediator, Organic Chemistry, General Medicine, Lipid signaling, Transfection, Molecular Docking Simulation, Anti-Inflammatory Agent, 030104 developmental biology, chemistry, Lipid mediator, Arachidonate 5-lipoxygenase, biology.protein, medicine.symptom, Human, medicine.drug