نتائج البحث - "Lipoxygenase"

1

The Protective Roles of Butein on Indomethacin Induced Gastric Ulcer in Mice

المؤلفون: Rustem Anil Ugan, Harun Un

المساهمون: Belirlenecek

المصدر: Eurasian Journal of Medicine, Vol 52, Iss 3, Pp 265-270 (2020)
Eurasian J Med

مصطلحات موضوعية: 0301 basic medicine, mice, Extract, Lipoxygenase, Generation, Pharmacology, Butein, medicine.disease_cause, Superoxide dismutase, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, indomethacin, medicine, Inhibition, Flavonoids, ulcer, lcsh:R5-920, biology, Rhus-Verniciflua Stokes, business.industry, Stomach, Induced Expression, Antioxidant Activity, General Medicine, Glutathione, Malondialdehyde, Nitric-Oxide, Famotidine, 030104 developmental biology, medicine.anatomical_structure, chemistry, 030220 oncology & carcinogenesis, biology.protein, Original Article, Quercetin, Gastritis, medicine.symptom, business, lcsh:Medicine (General), Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0260ae15552b67c92eff2b96d64de3Test
https://eajm.org/en/the-protective-roles-of-butein-on-indomethacin-induced-gastric-ulcer-inTest-mice-133299

2

Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation

المساهمون: Cheung, Sun-Yee, Werner, Marku, Esposito, Lucia, Troisi, Fabiana, Cantone, Vincenza, Liening, Stefanie, König, Stefanie, Gerstmeier, Jana, Koeberle, Andrea, Bilancia, Rossella, Rizza, Roberta, Rossi, Antonietta, Roviezzo, Fiorentina, Temml, Veronika, Schuster, Daniela, Stuppner, Hermann, Schubert-Zsilavecz, Manfred, Werz, Oliver, Hanke, Thoma, Pace, Simona

المصدر: European Journal of Medicinal Chemistry. 156:815-830

مصطلحات موضوعية: Male, 0301 basic medicine, Macrophage, Prostaglandin, Inflammation, Lipoxygenase Inhibitor, Proximity ligation assay, Pharmacology, Sulfonamide, Prostaglandin-E Synthase, Mice, 03 medical and health sciences, chemistry.chemical_compound, HEK293 Cell, Biosynthesis, Drug Discovery, medicine, Microsomal prostaglandin E2 synthase-1, Prostaglandin E2, Cells, Cultured, 5-Lipoxygenase, Arachidonate 5-Lipoxygenase, biology, Animal, Drug Discovery3003 Pharmaceutical Science, Specialized pro-resolving mediator, Organic Chemistry, General Medicine, Lipid signaling, Transfection, Molecular Docking Simulation, Anti-Inflammatory Agent, 030104 developmental biology, chemistry, Lipid mediator, Arachidonate 5-lipoxygenase, biology.protein, medicine.symptom, Human, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424c429e9a07ec2db7a177be38704e75Test
https://doi.org/10.1016/j.ejmech.2018.07.031Test

3

Lipoxygenase inhibitor ML351 dysregulated an innate inflammatory response leading to impaired cardiac repair in acute heart failure

المؤلفون: Ganesh V. Halade, Laurence M. Black, Vasundhara Kain, Bochra Tourki

المصدر: Biomedicine & Pharmacotherapy, Vol 139, Iss, Pp 111574-(2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Population, Inflammation, RM1-950, Naphthalenes, Pharmacology, Arachidonate 12-Lipoxygenase, Systemic inflammation, Proinflammatory cytokine, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Leukocytes, Animals, Arachidonate 15-Lipoxygenase, Medicine, Lipoxygenase Inhibitors, Myocardial infarction, education, Heart Failure, education.field_of_study, Arachidonate 5-Lipoxygenase, biology, business.industry, Anti-Inflammatory Agents, Non-Steroidal, Isoxazoles, General Medicine, Macrophage Activation, Lipoxygenases, medicine.disease, Immunity, Innate, Resolution of inflammation, Mice, Inbred C57BL, 030104 developmental biology, Integrin alpha M, Echocardiography, 030220 oncology & carcinogenesis, Heart failure, Macrophages, Peritoneal, biology.protein, Therapeutics. Pharmacology, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c66644e33199c9ea3d5948237bbb430Test
https://doi.org/10.1016/j.biopha.2021.111574Test

4

Structural insight into the optimization of ethyl 5-hydroxybenzo[g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/mPGES-1 dual inhibitors able to suppress inflammation

المؤلفون: Oliver Werz, Maxim B. Nawrozkij, Suann Errico, Antonio Fiorentino, Francesca Guida, Abdurrahman Olğaç, Sabatino Maione, Arthur S. Mkrtchyan, Simona Pace, Mario De Rosa, Rosa Maisto, Ferdinando Bruno, Rosanna Filosa, Michele D'Amico, Erden Banoglu

المساهمون: Bruno, Ferdinando, Errico, Suann, Pace, Simona, Nawrozkij, Maxim B., Mkrtchyan, Arthur S., Guida, Francesca, Maisto, Rosa, Olgaç, Abdurrahman, D'Amico, Michele, Maione, Sabatino, DE ROSA, Mario, C, Erden Banoglu, Werz, Oliver, Fiorentino, Antonio, Filosa, Rosanna

مصطلحات موضوعية: 0301 basic medicine, Male, Indoles, Stereochemistry, Neutrophils, Inflammation, Carrageenan, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, 0302 clinical medicine, Drug Discovery, medicine, Structure–activity relationship, Animals, Edema, Humans, Lipoxygenase Inhibitors, Prostaglandin E2, Prostaglandin-E Synthases, Pharmacology, Mice, Inbred ICR, Arachidonate 5-Lipoxygenase, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, 030104 developmental biology, Key factors, 030220 oncology & carcinogenesis, Microsome, Structure based, lipids (amino acids, peptides, and proteins), Arachidonic acid, medicine.symptom, medicine.drug